pyrazole has been researched along with phenobarbital in 27 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (37.04) | 18.7374 |
1990's | 14 (51.85) | 18.2507 |
2000's | 3 (11.11) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Berthou, F; Cauvin, JM; Deitrich, RA; Lucas, D; Ménez, JF | 1 |
Khan, S; O'Brien, PJ; Quan, Z | 1 |
Hahnemann, B; Honkakoski, P; Juvonen, R; Lang, MA; Mäenpää, J; Pasanen, M; Pelkonen, O; Raunio, H; Salonpää, P | 1 |
Cederbaum, AI; Clejan, LA | 1 |
Cederbaum, AI; Winters, DK | 2 |
Aida, K; Negishi, M | 1 |
Burnett, AK; Craft, JA; Lambard, SE; Wolf, CR | 1 |
Elovaara, E; Gelboin, HV; Hietanen, E; Nakajima, T; Park, SS; Vainio, H | 1 |
Gelboin, HV; Honkakoski, P; Järvinen, P; Juvonen, R; Kojo, A; Lang, MA; Park, SS; Pelkonen, O; Raunio, H; Vähäkangas, K | 1 |
Brunk, G; Gold, B | 1 |
Farber, J; Gold, B; Rogan, E | 1 |
Cederbaum, AI; Feierman, DE | 1 |
Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
Dietz, D; Kornbrust, D | 1 |
Kasuya, Y; Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
Abdel-Tawab, GA; El-Bassiouni, EA; El-Sebae, AH; El-Sewedy, SM; El-Zoghby, SM; Mostafa, MH; Ramadan, M | 1 |
Ingelman-Sundberg, M; Jörnvall, H | 1 |
Bartsch, H; Kirby, GM; Lang, MA; Pelkonen, P; Wild, CP | 1 |
Kharasch, ED; Thummel, KE | 1 |
Geneste, O; Lang, MA; Raffalli, F | 1 |
Commandeur, JN; Ploemen, JH; van Bladeren, P; van Ommen, B; Vermeulen, NP; Wormhoudt, LW | 1 |
Elovaara, E; Lautala, P; Luukkanen, L; Taskinen, J; Vainio, H | 1 |
De Curtis, V; Fabrizi, L; Gemma, S; Gervasi, P; Testai, E; Vittozzi, L | 1 |
Strobel, H; Vasquez, H | 1 |
Amato, G; Chiappe, C; De Rubertis, A; Gervasi, PG; Piegari, G | 1 |
Bergström, U; Brittebo, EB; Fernández, EL; Franzén, A; Lang, M; Piras, E; Raffalli-Mathieu, F | 1 |
27 other study(ies) available for pyrazole and phenobarbital
Article | Year |
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Differences in hepatic microsomal cytochrome P-450 isoenzyme induction by pyrazole, chronic ethanol, 3-methylcholanthrene, and phenobarbital in high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats.
Topics: Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Isoenzymes; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenotype; Pyrazoles; Rats; Rats, Inbred Strains; Selection, Genetic; Species Specificity | 1992 |
Role of cytochrome P-450IIE1 in N-nitroso-N-methylaniline induced hepatocyte cytotoxicity.
Topics: Alcohols; Animals; Aryl Hydrocarbon Hydroxylases; Cell Survival; Chloroform; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Liver; Male; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Steroid Hydroxylases | 1992 |
Effect of pyrazole, cobalt and phenobarbital on mouse liver cytochrome P-450 2a-4/5 (Cyp2a-4/5) expression.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Western; Cell Nucleus; Cobalt; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Isoenzymes; Kinetics; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Molecular Sequence Data; Oligodeoxyribonucleotides; Phenobarbital; Polymerase Chain Reaction; Pyrazoles; RNA, Messenger; Steroid Hydroxylases | 1992 |
Role of cytochrome P450 in the oxidation of glycerol by reconstituted systems and microsomes.
Topics: Animals; Antibodies; Antibodies, Monoclonal; Antioxidants; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Glycerol; Kinetics; Miconazole; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Oxidants; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats | 1992 |
The content and activity of cytochrome P450 2E1 in liver microsomes from alcohol-preferring and non-preferring rats.
Topics: Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Fomepizole; Immunoblotting; Methylcholanthrene; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1992 |
Posttranscriptional regulation of coumarin 7-hydroxylase induction by xenobiotics in mouse liver: mRNA stabilization by pyrazole.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Blotting, Northern; Cell Nucleus; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Enzyme Induction; Gene Expression Regulation, Enzymologic; Kinetics; Liver; Male; Mice; Mice, Inbred DBA; Mixed Function Oxygenases; Phenobarbital; Pyrazoles; RNA, Messenger; Transcription, Genetic; Xenobiotics | 1991 |
The role of specific cytochromes P450 in the formation of 7,12-dimethylbenz(a)anthracene-protein adducts in rat liver microsomes in vitro.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Azo Compounds; Benzoflavones; Blotting, Western; Clofibrate; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Female; Isoenzymes; Metyrapone; Microsomes, Liver; Phenobarbital; Pyrazoles; Rats; Troleandomycin | 1991 |
Oxidation of glycerol to formaldehyde by rat liver microsomes. Effects of cytochrome P-450 inducing agents.
Topics: Acetone; Aldehyde Oxidoreductases; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Fomepizole; Formaldehyde; Glycerol; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NAD; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1990 |
Immunochemical characterization of cytochrome P-450 isozymes responsible for benzene oxidation in the rat liver.
Topics: Animals; Benzene; Cytochrome P-450 Enzyme System; Ethanol; Fasting; Isoenzymes; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Reference Values | 1989 |
Mouse hepatic cytochrome P-450 isozyme induction by 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene, pyrazole, and phenobarbital.
Topics: Animals; Antibodies, Monoclonal; Blotting, Western; Cytochrome P-450 Enzyme System; Enzyme Induction; Glutamate-Cysteine Ligase; Isoenzymes; Mice; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; Phenobarbital; Pyrazoles; Pyridines | 1988 |
The effect of pyrazole, phenobarbital, ethanol and 3-methylcholanthrene pretreatment on the in vivo and in vitro genotoxicity of N-nitrosopyrrolidine.
Topics: Animals; DNA Damage; Ethanol; Liver; Male; Methylcholanthrene; Mutagenicity Tests; Mutagens; Mutation; N-Nitrosopyrrolidine; Nitrosamines; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1988 |
An investigation of the metabolism of N-nitroso-N-methylaniline by phenobarbital- and pyrazole-induced Sprague-Dawley rat liver and esophagus derived S-9.
Topics: Animals; Biotransformation; Electrochemistry; Enzyme Induction; Esophagus; In Vitro Techniques; Liver; Male; Mutagenicity Tests; Mutagens; Nitrosamines; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains; Subcellular Fractions | 1987 |
Increased sensitivity of the microsomal oxidation of ethanol to inhibition by pyrazole and 4-methylpyrazole after chronic ethanol treatment.
Topics: Animals; Cytochrome P-450 Enzyme System; Ethanol; Fomepizole; Male; Methylcholanthrene; Microsomes; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1987 |
Different effects of chemicals on metabolism of N-nitrosamines in rat liver.
Topics: Animals; Dimethylnitrosamine; Ethanol; Liver; Methylcholanthrene; Nitrosamines; Phenobarbital; Pyrazoles; Rats | 1987 |
Effects of pretreatment with pyrazole and inducers of mixed function oxidases on DNA repair elicited by dimethylnitrosamine in rat hepatocytes in vivo and in vitro.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP2E1; DDT; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Liver; Male; Methyl Methanesulfonate; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1985 |
Nature of N-nitrosodimethylamine demethylase in hepatic microsomes of rats.
Topics: Aminoacetonitrile; Aminopyrine N-Demethylase; Aniline Compounds; Animals; Benzoflavones; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Imidazoles; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Monoamine Oxidase; Niacinamide; Oxidoreductases, N-Demethylating; Phenobarbital; Proadifen; Pyrazoles; Rats; Rats, Inbred Strains; Tranylcypromine | 1984 |
Effect of some xenobiotics on kynurenine hydrolase and kynurenine aminotransferase of mouse liver.
Topics: Animals; Aroclors; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carcinogens; Chlorodiphenyl (54% Chlorine); Chlorpromazine; Female; Hydrolases; Liver; Lyases; Methylcholanthrene; Mice; Phenobarbital; Pyrazoles; Transaminases | 1983 |
Induction of the ethanol-inducible form of rabbit liver microsomal cytochrome P-450 by inhibitors of alcohol dehydrogenase.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acids; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Imidazoles; Immunodiffusion; Male; Microsomes, Liver; Phenobarbital; Pyrazoles; Rabbits | 1984 |
Metabolism of nitrosamines and aflatoxin B1 by hamster liver CYP2A enzymes.
Topics: Aflatoxin B1; Animals; Blotting, Western; Coumarins; Cricetinae; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Female; Kinetics; Male; Mesocricetus; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Phenobarbital; Pyrazoles; Steroid Hydroxylases | 1994 |
Human alfentanil metabolism by cytochrome P450 3A3/4. An explanation for the interindividual variability in alfentanil clearance?
Topics: Alfentanil; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 Enzyme System; Humans; In Vitro Techniques; Liver; Male; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Pyrazoles; Rats; Rats, Sprague-Dawley | 1993 |
Identification and characterization of a 44 kDa protein that binds specifically to the 3'-untranslated region of CYP2a5 mRNA: inducibility, subcellular distribution and possible role in mRNA stabilization.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Binding Sites; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; DNA, Complementary; Drug Stability; Liver; Male; Mice; Mice, Inbred DBA; Mixed Function Oxygenases; Molecular Sequence Data; Molecular Weight; Phenobarbital; Poly A; Pyrazoles; RNA-Binding Proteins; RNA, Messenger; Subcellular Fractions | 1996 |
Cytochrome P450 catalyzed metabolism of 1,2-dibromoethane in liver microsomes of differentially induced rats.
Topics: Acetaldehyde; Adenosine; Animals; Benzoflavones; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Ethylene Dibromide; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Isoenzymes; Kinetics; Male; Microsomes, Liver; Molecular Structure; NADP; Phenobarbital; Pyrazoles; Rats; Rats, Wistar; Temperature | 1996 |
Characterization of 1-hydroxypyrene as a novel marker substrate of 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase(s).
Topics: Acetone; Animals; Carcinogens; Chromatography, High Pressure Liquid; Creosote; Enzyme Induction; Enzyme Inhibitors; Glucuronates; Glucuronosyltransferase; Magnetic Resonance Spectroscopy; Male; Methylcholanthrene; Methylenebis(chloroaniline); Microsomes, Liver; Mutagens; Phenobarbital; Polychlorinated Biphenyls; Pyrazoles; Pyrenes; Rats; Rats, Wistar; Substrate Specificity | 1997 |
The role of different cytochrome P450 isoforms in in vitro chloroform metabolism.
Topics: Acetone; Animals; Aryl Hydrocarbon Hydroxylases; beta-Naphthoflavone; Biotransformation; Chloroform; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Cytochrome P450 Family 2; Dexamethasone; Drug Synergism; Enzyme Induction; Isoenzymes; Male; Microsomes, Liver; Phenobarbital; Pyrazoles; Rats; Rats, Sprague-Dawley; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 1996 |
Role of cytochrome P450 in DNA damage produced by treatment of colon cells with 1,2-dimethylhydrazine.
Topics: 1,2-Dimethylhydrazine; Benz(a)Anthracenes; Carcinogens; Colon; Cytochrome P-450 Enzyme System; DNA; DNA Damage; Enzyme Activators; Glutathione; Guanine; Humans; Hypnotics and Sedatives; Methyltransferases; Phenobarbital; Pyrazoles | 2001 |
Stereochemical aspects in the 4-vinylcyclohexene biotransformation with rat liver microsomes and purified cytochrome P450s: diepoxide formation and hydrolysis.
Topics: Animals; Biotransformation; Chromatography, Gas; Cyclohexanes; Cyclohexenes; Cytochrome P-450 Enzyme System; Dexamethasone; Enzyme Induction; Epoxy Compounds; Hydrolysis; Isoenzymes; Male; Microsomes, Liver; Molecular Conformation; Phenobarbital; Pyrazoles; Rats; Rats, Sprague-Dawley | 2003 |
Cell-specific expression of CYP2A5 in the mouse respiratory tract: effects of olfactory toxicants.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P450 Family 2; Environmental Pollutants; Enzyme Induction; Female; Immunohistochemistry; In Situ Hybridization; Male; Methimazole; Mice; Mice, Inbred DBA; Mixed Function Oxygenases; Nasolacrimal Duct; Nitriles; Olfactory Mucosa; Phenobarbital; Pyrazoles; Respiratory System; Salivary Glands | 2003 |