pyrazole and disulfiram

pyrazole has been researched along with disulfiram in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19909 (60.00)18.7374
1990's4 (26.67)18.2507
2000's1 (6.67)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Khan, S; Lauriault, VV; O'Brien, PJ1
Horvath, JJ; Witmer, CM; Witz, G1
Cunningham, ML; McMahon, TF1
Beck, O; Eriksson, CJ; Kiianmaa, K; Lundman, A1
Ohno, Y; Ormstad, K; Orrenius, S; Ross, D1
Jones, TW; Ohno, Y; Ormstad, K1
George, WJ; Gershanik, JJ; Lertora, JJ; McCloskey, SE; White, L1
Cook, MW; Creasy, DM; Foster, PM; Gray, TJ; Moss, EJ; Thomas, LV; Walters, DG1
Eriksson, CJ1
Fukui, Y; Matsubara, K; Nakahara, M; Takahashi, S1
Creasy, DM; Foster, JR; Foster, PM; Gray, TJ1
Iwasaki, K; Noguchi, H1
Perilli, E; Perin, A; Sessa, A; Tunici, P1
Howes, D; Lockley, DJ; Williams, FM1
Beike, J; Bender, K; Jübner, M; Käferstein, H; Lenz, D; Rothschild, MA; Wintermeyer, A1

Other Studies

15 other study(ies) available for pyrazole and disulfiram

ArticleYear
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration.
    Chemico-biological interactions, 1992, Volume: 81, Issue:3

    Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfiram; Ditiocarb; Liver Diseases; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Pyrazoles; Rats; Rats, Inbred Strains

1992
Nephrotoxicity of the 1:1 acrolein-glutathione adduct in the rat.
    Toxicology and applied pharmacology, 1992, Volume: 117, Issue:2

    Topics: Acrolein; Animals; Disulfiram; Glutathione; Isoxazoles; Kidney Diseases; Kidney Tubules, Proximal; Male; Probenecid; Pyrazoles; Rats; Rats, Sprague-Dawley

1992
Mutagenicity of methylazoxymethanol acetate in the presence of alcohol dehydrogenase, aldehyde dehydrogenase, and rat liver microsomes in Salmonella typhimurium His G46.
    Environmental and molecular mutagenesis, 1991, Volume: 18, Issue:3

    Topics: Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Biotransformation; Cytosol; Disulfiram; Esterases; Kinetics; Liver; Male; Methylazoxymethanol Acetate; Microsomes, Liver; Mutagenicity Tests; Mutagens; NAD; NADP; Pyrazoles; Rats; Rats, Inbred F344; Salmonella typhimurium; Swine

1991
5-Hydroxyindoleacetic acid and 5-hydroxytryptophol levels in rat brain: effects of ethanol, pyrazole, cyanamide and disulfiram treatment.
    Drug and alcohol dependence, 1986, Volume: 16, Issue:4

    Topics: Animals; Brain; Cyanamide; Cyanides; Diencephalon; Disulfiram; Ethanol; Hydroxyindoleacetic Acid; Hydroxytryptophol; Indoles; Male; Medulla Oblongata; Pons; Pyrazoles; Rats; Serotonin

1986
Mechanism of allyl alcohol toxicity and protective effects of low-molecular-weight thiols studied with isolated rat hepatocytes.
    Toxicology and applied pharmacology, 1985, Volume: 78, Issue:2

    Topics: 1-Propanol; Acrolein; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Animals; Cell Survival; Chromatography, High Pressure Liquid; Cytosol; Disulfiram; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; Liver; Male; Propanols; Pyrazoles; Rats; Rats, Inbred Strains

1985
Allyl alcohol toxicity in isolated renal epithelial cells: protective effects of low molecular weight thiols.
    Chemico-biological interactions, 1985, Volume: 52, Issue:3

    Topics: 1-Propanol; Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Biotransformation; Chromatography, High Pressure Liquid; Disulfiram; Drug Interactions; Female; Glutathione; Kidney; Liver; Male; Propanols; Pyrazoles; Rats; Rats, Inbred Strains; Sex Factors; Sulfhydryl Compounds

1985
Toxicity of benzyl alcohol in adult and neonatal mice.
    Journal of pharmaceutical sciences, 1986, Volume: 75, Issue:7

    Topics: Aging; Animals; Animals, Newborn; Benzaldehydes; Benzyl Alcohol; Benzyl Alcohols; Benzyl Compounds; Disulfiram; Lethal Dose 50; Male; Mice; Pyrazoles

1986
The role of metabolism in 2-methoxyethanol-induced testicular toxicity.
    Toxicology and applied pharmacology, 1985, Volume: 79, Issue:3

    Topics: Acetates; Animals; Chromatography, High Pressure Liquid; Disulfiram; Ethylene Glycols; Gas Chromatography-Mass Spectrometry; Male; Mass Spectrometry; Pyrazoles; Rats; Rats, Inbred Strains; Seminiferous Tubules; Testis

1985
Endogenous acetaldehyde in rats. Effects of exogenous ethanol, pyrazole, cyanamide and disulfiram.
    Biochemical pharmacology, 1985, Nov-15, Volume: 34, Issue:22

    Topics: Acetaldehyde; Animals; Cyanamide; Cyanides; Disulfiram; Eating; Ethanol; Male; Pyrazoles; Rats

1985
Acute effects of ethanol and acetaldehyde on plasma phosphate level.
    The Journal of pharmacy and pharmacology, 1982, Volume: 34, Issue:6

    Topics: Acetaldehyde; Acetates; Acetic Acid; Animals; Disulfiram; Ethanol; Male; Phosphates; Pyrazoles; Rabbits; Time Factors

1982
Testicular toxicity produced by ethylene glycol monomethyl and monoethyl ethers in the rat.
    Environmental health perspectives, 1984, Volume: 57

    Topics: Acetates; Animals; Biotransformation; Cells, Cultured; Disulfiram; Ethylene Glycols; Male; Organ Size; Pargyline; Pyrazoles; Rats; Seminiferous Tubules; Testicular Diseases; Testis; Time Factors; Tissue Distribution

1984
Metabolism of tiaramide in vitro. II. Oxidation of piperazineethanol group in tiaramide by 105 000 g supernatants from monkey and rat liver.
    Xenobiotica; the fate of foreign compounds in biological systems, 1982, Volume: 12, Issue:8

    Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Benzothiazoles; Disulfiram; In Vitro Techniques; Isoelectric Focusing; Liver; Macaca mulatta; Male; Oxidation-Reduction; Piperazines; Pyrazoles; Rats; Rats, Inbred Strains; Subcellular Fractions

1982
Transglutaminase activity in rat liver after acute ethanol administration.
    Biochimica et biophysica acta, 1995, Dec-14, Volume: 1245, Issue:3

    Topics: Animals; Disulfiram; Enzyme Inhibitors; Ethanol; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Transglutaminases

1995
Cutaneous metabolism of glycol ethers.
    Archives of toxicology, 2005, Volume: 79, Issue:3

    Topics: Alcohol Dehydrogenase; Alcohol Deterrents; Aldehyde Dehydrogenase; Animals; Cytosol; Disulfiram; Enzyme Inhibitors; Ethanol; Ethylene Glycols; In Vitro Techniques; Liver; Male; NAD; Oxidation-Reduction; Pyrazoles; Rats; Rats, Wistar; Skin; Skin Absorption; Solvents

2005
Inhibition of 1,4-butanediol metabolism in human liver in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:6

    Topics: Adult; Aged; Antidotes; Butylene Glycols; Cimetidine; Disulfiram; Drug Interactions; Ethanol; Female; Fomepizole; Gas Chromatography-Mass Spectrometry; Humans; Hydroxybutyrates; In Vitro Techniques; Liver; Male; Middle Aged; Pyrazoles

2011