pyrazole has been researched along with dimethylnitrosamine in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 5 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Khan, S; Lauriault, VV; O'Brien, PJ | 1 |
| Cederbaum, AI; Winters, DK | 1 |
| Cederbaum, AI; Dicker, E | 1 |
| Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
| Tu, YY; Yang, CS | 1 |
| Dietz, D; Kornbrust, D | 1 |
| Kasuya, Y; Kawanishi, T; Ohno, Y; Omori, Y; Takahashi, A; Takanaka, A | 1 |
| Brown, C; Evarts, RP; Haliday, E; Raab, MM | 1 |
| Bartsch, H; Béréziat, JC; Camus, AM; Geneste, O; Henderson, CJ; Honkakoski, P; Lang, MA; Wolf, CR | 1 |
| Cederbaum, AI; Wu, D | 1 |
10 other study(ies) available for pyrazole and dimethylnitrosamine
| Article | Year |
|---|---|
Hepatocyte cytotoxicity induced by various hepatotoxins mediated by cytochrome P-450IIE1: protection with diethyldithiocarbamate administration.
Topics: Animals; Carbon Disulfide; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Disulfiram; Ditiocarb; Liver Diseases; Male; Microsomes, Liver; NADP; Oxidoreductases, N-Demethylating; Pyrazoles; Rats; Rats, Inbred Strains | 1992 |
Time course characterization of the induction of cytochrome P-450 2E1 by pyrazole and 4-methylpyrazole.
Topics: Animals; Base Sequence; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Induction; Fomepizole; Immunoblotting; Male; Molecular Sequence Data; Nitrophenols; Oligonucleotide Probes; Oxazines; Oxidoreductases, N-Demethylating; Pyrazoles; Rats; Rats, Inbred Strains; RNA, Messenger; Time Factors | 1992 |
Increased oxidation of dimethylnitrosamine in pericentral microsomes after pyrazole induction of cytochrome P-4502E1.
Topics: Animals; Culture Techniques; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Induction; gamma-Glutamyltransferase; Glutamate-Ammonia Ligase; Male; Microsomes, Liver; Pyrazoles; Rats; Rats, Inbred Strains | 1991 |
Different effects of chemicals on metabolism of N-nitrosamines in rat liver.
Topics: Animals; Dimethylnitrosamine; Ethanol; Liver; Methylcholanthrene; Nitrosamines; Phenobarbital; Pyrazoles; Rats | 1987 |
Demethylation and denitrosation of nitrosamines by cytochrome P-450 isozymes.
Topics: Amitrole; Animals; Benzphetamine; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ethanol; Free Radicals; Isoenzymes; Kinetics; Male; Microsomes, Liver; Nitrosamines; Phenethylamines; Proadifen; Pyrazoles; Rats; Rats, Inbred Strains; Substrate Specificity; Superoxide Dismutase | 1985 |
Effects of pretreatment with pyrazole and inducers of mixed function oxidases on DNA repair elicited by dimethylnitrosamine in rat hepatocytes in vivo and in vitro.
Topics: Animals; Aroclors; Benzoflavones; beta-Naphthoflavone; Cells, Cultured; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 CYP2E1; DDT; Diethylnitrosamine; Dimethylnitrosamine; DNA Repair; Enzyme Induction; Liver; Male; Methyl Methanesulfonate; Methylcholanthrene; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1985 |
New method for quantitative measurement of N-nitrosodimethylamine formation in the whole mouse.
Topics: Aminopyrine; Animals; Chromatography, Gas; Dimethylnitrosamine; Dose-Response Relationship, Drug; Half-Life; Male; Mice; Pyrazoles; Sodium Nitrite | 1983 |
Pyrazole effects on mutagenicity and toxicity of dimethylnitrosamine in Wistar rats.
Topics: Animals; Dimethylnitrosamine; Lethal Dose 50; Male; Microsomes, Liver; Mutagenicity Tests; Mutation; Proteins; Pyrazoles; Rats; Rats, Inbred Strains | 1983 |
High variability of nitrosamine metabolism among individuals: role of cytochromes P450 2A6 and 2E1 in the dealkylation of N-nitrosodimethylamine and N-nitrosodiethylamine in mice and humans.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP2A6; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Diethylnitrosamine; Dimethylnitrosamine; Humans; Kinetics; Male; Mice; Mice, Inbred DBA; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases, N-Demethylating; Pyrazoles; Reference Values | 1993 |
Induction of liver cytochrome P4502E1 by pyrazole and 4-methylpyrazole in neonatal rats.
Topics: Animals; Animals, Newborn; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Enzyme Induction; Female; Fomepizole; Liver; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Pregnancy; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger | 1993 |