pyrazole and celecoxib

pyrazole has been researched along with celecoxib in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Abd El Razik, HA; Bekhit, AA; Bistawroos, AA; El-Mallah, A; Mohy El-Din, MM; Nour El-Din, NA; Senbel, AM1
Abdelall, EK; Kamel, GM1
Baset, MA; El-Eraky, WI; Fahmy, HH; Khalifa, NM; Nossier, ES1
Abdellatif, KR; Amin, NH; El-Saadi, MT; Elzayat, SG1
Abdellatif, KRA; Elshaier, YAMM; Fadaly, WAA; Hassanein, EHM1

Other Studies

5 other study(ies) available for pyrazole and celecoxib

ArticleYear
A novel COX-2 inhibitor pyrazole derivative proven effective as an anti-inflammatory and analgesic drug.
    Basic & clinical pharmacology & toxicology, 2011, Volume: 108, Issue:4

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Benzenesulfonamides; Carrageenan; Celecoxib; Chronic Disease; Cyclooxygenase 2 Inhibitors; Drug Evaluation, Preclinical; Edema; Female; Formaldehyde; Hyperalgesia; Indomethacin; Inflammation; Male; Mice; Pyrazoles; Rats; Sulfonamides; Ulcer

2011
Synthesis of new thiazolo-celecoxib analogues as dual cyclooxygenase-2/15-lipoxygenase inhibitors: Determination of regio-specific different pyrazole cyclization by 2D NMR.
    European journal of medicinal chemistry, 2016, Aug-08, Volume: 118

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 15-Lipoxygenase; Cattle; Celecoxib; Chemistry Techniques, Synthetic; Cyclization; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Lipoxygenase Inhibitors; Magnetic Resonance Spectroscopy; Male; Pyrazoles; Rats; Stereoisomerism; Thiazoles; Ulcer

2016
Design and Synthesis of Novel Pyrazole-Substituted Different Nitrogenous Heterocyclic Ring Systems as Potential Anti-Inflammatory Agents.
    Molecules (Basel, Switzerland), 2017, Mar-24, Volume: 22, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Celecoxib; Cyclooxygenase Inhibitors; Drug Design; Edema; Heterocyclic Compounds; Injections; Male; Molecular Docking Simulation; Piperidines; Pyrazoles; Rats; Rimonabant

2017
New substituted pyrazole derivatives targeting COXs as potential safe anti-inflammatory agents.
    Future medicinal chemistry, 2019, Volume: 11, Issue:15

    Topics: Animals; Anti-Inflammatory Agents; Binding Sites; Catalytic Domain; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Edema; Hydrogen Bonding; Male; Molecular Docking Simulation; Pyrazoles; Rats; Rats, Wistar; Structure-Activity Relationship

2019
New 1,2,4-triazole/pyrazole hybrids linked to oxime moiety as nitric oxide donor celecoxib analogs: Synthesis, cyclooxygenase inhibition anti-inflammatory, ulcerogenicity, anti-proliferative activities, apoptosis, molecular modeling and nitric oxide relea
    Bioorganic chemistry, 2020, Volume: 98

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Celecoxib; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Models, Molecular; Molecular Structure; Nitric Oxide; Oximes; PC-3 Cells; Pyrazoles; Rats; Rats, Wistar; Stomach Ulcer; Structure-Activity Relationship; Triazoles

2020