pyrazole has been researched along with arachidonic acid in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cederbaum, AI; Wu, D | 2 |
| Cederbaum, AI; Marí, M; Nieto, N | 1 |
| Zhuge, J | 1 |
4 other study(ies) available for pyrazole and arachidonic acid
| Article | Year |
|---|---|
Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1.
Topics: Animals; Arachidonic Acid; Caspases; Cells, Cultured; Chromans; Cytochrome c Group; Cytochrome P-450 CYP2E1; Cytosol; Disulfides; Enzyme Activation; Ethanol; Flow Cytometry; Liver; Male; Oligopeptides; Oxidative Stress; Pyrazoles; Rats; Rats, Sprague-Dawley | 2000 |
Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes.
Topics: Allyl Compounds; Animals; Antioxidants; Apoptosis; Arachidonic Acid; Carcinoma, Hepatocellular; Cell Survival; Cells, Cultured; Chromans; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Synergism; Hepatocytes; Humans; Lipid Peroxidation; Male; Mixed Function Oxygenases; Protein Synthesis Inhibitors; Pyrazoles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium Salicylate; Sulfides | 2001 |
Cytochrome P450 2E1 responsiveness in the promoter of glutamate-cysteine ligase catalytic subunit.
Topics: 5' Flanking Region; Allyl Compounds; Animals; Antioxidants; Arachidonic Acid; Carcinoma, Hepatocellular; Catalase; Catalytic Domain; Central Nervous System Depressants; Cytochrome P-450 CYP2E1; Enzyme Inhibitors; Ethanol; Gene Deletion; Gene Expression; Genes, Reporter; Glutamate-Cysteine Ligase; Glutathione; Humans; Iron; Liver Neoplasms; Luciferases; Promoter Regions, Genetic; Pyrazoles; Rats; Response Elements; RNA, Messenger; Sulfides; Tumor Cells, Cultured | 2003 |
A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1.
Topics: Animals; Apoptosis; Arachidonic Acid; Cell Survival; Cycloleucine; Cytochrome P-450 CYP2E1; Cytotoxins; Drug Synergism; Hepatocytes; Lipid Peroxidation; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; S-Adenosylmethionine | 2008 |