Compounds > pyrazole

pyrazole and allopurinol

pyrazole has been researched along with allopurinol in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's2 (22.22)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cederbaum, AI; Puntarulo, S1
Sultatos, LG1
Berl, L; Cederbaum, AI1
Dudley, BF; Winston, GW1
Casciano, D; Fu, PP; Heinze, TM; Kadlubar, FF; Lloyd, RV; Ni, YC; Shelton, S; Wong, TY1
Decker, RW; Malejka-Giganti, D; Ritter, CL1
Akaho, E; Ali, HI; Fujita, T; Nagamatsu, T1
Beedkar, SD; Chobe, SS; Dawane, BS; Khobragade, CN; Yemul, OS1
Ding, WZ; Li, Z; Sun, ZG; Zhou, XJ; Zhu, HL; Zhu, ML1

Other Studies

9 other study(ies) available for pyrazole and allopurinol

ArticleYear
Production of 4-hydroxypyrazole from the interaction of the alcohol dehydrogenase inhibitor pyrazole with hydroxyl radical.
    Archives of biochemistry and biophysics, 1987, Volume: 255, Issue:2

    Topics: Alcohol Dehydrogenase; Animals; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Male; Microsomes, Liver; Pyrazoles; Rats; Rats, Inbred Strains; Xanthine Oxidase

1987
Effects of acute ethanol administration on the hepatic xanthine dehydrogenase/oxidase system in the rat.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:3

    Topics: Acetaldehyde; Animals; Dithiothreitol; Dose-Response Relationship, Drug; Ethanol; Glutathione; Glutathione Disulfide; Ketone Oxidoreductases; Liver; Pyrazoles; Rats; Rats, Inbred Strains; Xanthine Dehydrogenase; Xanthine Oxidase

1988
Pyrazole and 4-methylpyrazole inhibit oxidation of ethanol and dimethyl sulfoxide by hydroxyl radicals generated from ascorbate, xanthine oxidase, and rat liver microsomes.
    Archives of biochemistry and biophysics, 1982, Volume: 216, Issue:2

    Topics: Animals; Ascorbic Acid; Dimethyl Sulfoxide; Ethanol; Fomepizole; Free Radicals; Hydroxides; Hydroxyl Radical; Kinetics; Male; Microsomes, Liver; Oxidation-Reduction; Pyrazoles; Rats; Rats, Inbred Strains; Xanthine Oxidase

1982
p-nitrosophenol reduction by liver cytosol from ADH-positive and -negative deermice (Peromyscus maniculatus).
    Archives of biochemistry and biophysics, 1995, Feb-01, Volume: 316, Issue:2

    Topics: Alcohol Dehydrogenase; Aldehyde Oxidase; Aldehyde Oxidoreductases; Aminophenols; Animals; Animals, Laboratory; Cytosol; Dicumarol; Liver; Mutation; NAD; NAD(P)H Dehydrogenase (Quinone); NADP; Nitroso Compounds; Peromyscus; Pyrazoles; Xanthine Oxidase

1995
Mouse liver microsomal metabolism of chloral hydrate, trichloroacetic acid, and trichloroethanol leading to induction of lipid peroxidation via a free radical mechanism.
    Drug metabolism and disposition: the biological fate of chemicals, 1996, Volume: 24, Issue:1

    Topics: Allopurinol; Animals; Catalysis; Cell Line; Chloral Hydrate; Ethylene Chlorohydrin; Free Radicals; Gas Chromatography-Mass Spectrometry; Horseradish Peroxidase; Humans; Lipid Peroxidation; Male; Mice; Microsomes, Liver; NAD; NADP; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Trichloroacetic Acid; Xanthine Oxidase

1996
Reductions of nitro and 9-Oxo groups of environmental nitrofluorenes by the rat mammary gland in vitro.
    Chemical research in toxicology, 2000, Volume: 13, Issue:8

    Topics: Air Pollutants; Allopurinol; Animals; Breast; Cytosol; Dicumarol; Female; Fluorenes; Hypoxanthine; Indomethacin; Microsomes; Niacinamide; Oxidation-Reduction; Oxygen; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Rutin; Vitamin K; Xanthine

2000
A comparative study of AutoDock and PMF scoring performances, and SAR of 2-substituted pyrazolotriazolopyrimidines and 4-substituted pyrazolopyrimidines as potent xanthine oxidase inhibitors.
    Journal of computer-aided molecular design, 2010, Volume: 24, Issue:1

    Topics: Animals; Catalytic Domain; Cattle; Enzyme Inhibitors; Models, Molecular; Protein Binding; Pyrazoles; Pyrimidines; Structure-Activity Relationship; Xanthine Oxidase

2010
Novel thiazolo-pyrazolyl derivatives as xanthine oxidase inhibitors and free radical scavengers.
    International journal of biological macromolecules, 2012, May-01, Volume: 50, Issue:4

    Topics: Allopurinol; Animals; Catalytic Domain; Drug Design; Enzyme Inhibitors; Free Radical Scavengers; Gout; Inhibitory Concentration 50; Models, Molecular; Pyrazoles; Rats; Thiazoles; Xanthine Oxidase

2012
Synthesis and Biological Evaluation of Novel Aryl-2H-pyrazole Derivatives as Potent Non-purine Xanthine Oxidase Inhibitors.
    Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:8

    Topics: Animals; Catalytic Domain; Cattle; Enzyme Inhibitors; Molecular Docking Simulation; Pyrazoles; Structure-Activity Relationship; Xanthine Oxidase

2015