pyrazolanthrone has been researched along with sirolimus in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (41.18) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A | 1 |
| Allen, WE; Campbell, M; Sawyer, C; Trimble, ER; Vanhaesebroeck, B | 1 |
| Beck, A; Fiedler, H; Häring, HU; Kellerer, M; Moeschel, K; Müssig, K; Staiger, H | 1 |
| Hanai, Y; Harada, A; Kato, H; Kozawa, O; Matsushima-Nishiwaki, R; Ogura, S; Ohta, T; Takai, S; Tokuda, H; Yasuda, E | 1 |
| Easton, JB; Houghton, PJ; Huang, S; Kriwacki, RW; Lacy, ER; Mishra, A; Xiao, L; Zhan, J | 1 |
| Choe, TB; Hong, SI; Jin, HO; Kim, ES; Kim, JI; Lee, HC; Park, IC; Seo, SK; Woo, SH; Yoo, DH | 1 |
| Asano, S; Itoh, M; Nishiwaki-Yasuda, K; Sekiguchi, S; Shibata, M; Suzuki, A | 1 |
| Kline, K; Sanders, BG; Tiwary, R; Yu, W | 1 |
| Benoit, M; Demartines, N; Dormond, O; Dormond-Meuwly, A | 1 |
| Bitterman, PB; Farassati, F; Jacobson, BA; Jay-Dixon, J; Jirakulaporn, T; Kratzke, RA; Patel, MR; Sadiq, AA | 1 |
| Chang, KT; Chen, HC; Hung, CC; Hung, CH; Hwang, SJ; Kuo, CH; Lin, HY; Lin, SF | 1 |
| Chen, L; Dong, X; Huang, S; Liu, C; Liu, L; Wang, X; Xu, C; Zhang, H; Zhu, Y | 1 |
| Fujita, K; Kainuma, S; Kawabata, T; Kozawa, O; Kuroyanagi, G; Matsushima-Nishiwaki, R; Otsuka, T; Sakai, G; Tokuda, H; Yamamoto, N | 1 |
| Das, HK; Hontiveros, SS | 1 |
| Bao, B; Chen, W; Guo, J; Pan, J; Zhang, D; Zhang, M | 1 |
17 other study(ies) available for pyrazolanthrone and sirolimus
| Article | Year |
|---|---|
The selectivity of protein kinase inhibitors: a further update.
Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera | 2007 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase | 2013 |
Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways.
Topics: Alkyl and Aryl Transferases; Androstadienes; Anthracenes; Antibodies, Monoclonal; Cells, Cultured; Chemotaxis; Chromones; Class I Phosphatidylinositol 3-Kinases; Farnesyltranstransferase; Flavonoids; Glucose; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lovastatin; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyisoprenyl Phosphates; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; ras Proteins; Sesquiterpenes; Sirolimus; TOR Serine-Threonine Kinases; Wortmannin | 2004 |
Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1.
Topics: Androstadienes; Animals; Anthracenes; Blotting, Western; Cells, Cultured; Chromatography, High Pressure Liquid; Densitometry; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Gene Transfer Techniques; Glutathione Transferase; Immunoassay; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Mice; Peptides; Phorbol Esters; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Rats; Retroviridae; Serine; Signal Transduction; Sirolimus; Transfection; Tumor Necrosis Factor-alpha; Wortmannin | 2005 |
Negative regulation by p70 S6 kinase of FGF-2-stimulated VEGF release through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts.
Topics: Animals; Anthracenes; Cells, Cultured; Fibroblast Growth Factor 2; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase 3; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Ribosomal Protein S6 Kinases, 70-kDa; RNA, Small Interfering; Sirolimus; Time Factors; Vascular Endothelial Growth Factor A | 2007 |
Negative regulation of ASK1 by p21Cip1 involves a small domain that includes Serine 98 that is phosphorylated by ASK1 in vivo.
Topics: Anthracenes; Cell Line; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; Mutation; Nuclear Localization Signals; Phosphoserine; Protein Binding; Protein Kinase Inhibitors; Sirolimus | 2007 |
SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression.
Topics: Activating Transcription Factor 4; Anthracenes; HeLa Cells; Humans; Mitogen-Activated Protein Kinase Kinases; Protein Kinase Inhibitors; Protein Kinases; RNA, Small Interfering; Sirolimus; TOR Serine-Threonine Kinases; Transcription Factors | 2009 |
Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells.
Topics: 3T3 Cells; Animals; Anthracenes; Butadienes; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Imidazoles; Mice; Morpholines; Naphthalenes; Nitriles; Osteoblasts; Phosphates; Prostaglandin D2; Pyridines; Signal Transduction; Sirolimus; Sodium | 2009 |
α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways.
Topics: 1-Phosphatidylinositol 4-Kinase; alpha-Tocopherol; Androstadienes; Anthracenes; Antioxidants; Apoptosis; Blotting, Western; Breast Neoplasms; Butadienes; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Immunosuppressive Agents; Insulin Receptor Substrate Proteins; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Nitriles; Phosphorylation; RNA, Small Interfering; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Tumor Cells, Cultured; Wortmannin | 2011 |
Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells.
Topics: Adenocarcinoma; Animals; Anthracenes; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Enzyme Inhibitors; Female; Humans; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Nude; Models, Animal; Phosphorylation; Signal Transduction; Sirolimus; Xenograft Model Antitumor Assays | 2011 |
Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation.
Topics: Adaptor Proteins, Signal Transducing; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma, Non-Small-Cell Lung; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Eukaryotic Initiation Factor-4G; Humans; JNK Mitogen-Activated Protein Kinases; Nucleocytoplasmic Transport Proteins; Phosphoproteins; Phosphorylation; Protein Binding; Protein Biosynthesis; RNA Caps; Sirolimus; TOR Serine-Threonine Kinases | 2012 |
Effects of the mTOR inhibitor rapamycin on monocyte-secreted chemokines.
Topics: Anthracenes; Cell Line; Cell Survival; Chemokines; Flavonoids; Humans; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Phosphorylation; Protein Kinase Inhibitors; Sirolimus; TOR Serine-Threonine Kinases | 2014 |
Rapamycin ameliorates cadmium-induced activation of MAPK pathway and neuronal apoptosis by preventing mitochondrial ROS inactivation of PP2A.
Topics: Animals; Anthracenes; Apoptosis; Butadienes; Cadmium; Genes, jun; MAP Kinase Signaling System; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinases; Neurons; Nitriles; PC12 Cells; Phosphorylation; Protein Phosphatase 2; Rats; Reactive Oxygen Species; Signal Transduction; Sirolimus | 2016 |
Heat shock protein 27 (HSPB1) suppresses the PDGF-BB-induced migration of osteoblasts.
Topics: Animals; Anthracenes; Becaplermin; Cell Line; Cell Movement; Flavonoids; HSP27 Heat-Shock Proteins; Imidazoles; Mice; Mitogen-Activated Protein Kinases; Osteoblasts; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-sis; Pyridines; Sirolimus | 2017 |
Inhibition of p-mTOR represses PS1 transcription by reducing p-JNK.
Topics: Anthracenes; Blotting, Western; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Humans; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Phosphorylation; Presenilin-1; RNA, Messenger; Signal Transduction; Sirolimus; TOR Serine-Threonine Kinases; Transcription, Genetic | 2020 |
Protective effect of berberine against LPS-induced endothelial cell injury via the JNK signaling pathway and autophagic mechanisms.
Topics: Adenine; Anthracenes; Autophagy; Berberine; Cell Proliferation; Cell Survival; Endothelial Cells; Human Umbilical Vein Endothelial Cells; Humans; Lipopolysaccharides; MAP Kinase Signaling System; Protective Agents; Sirolimus | 2021 |