pyrazolanthrone has been researched along with simvastatin in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, CC; Lee, TS; Shyy, JY; Zhu, Y | 1 |
| Gong, CH; Jin, SM; Kim, KS; Kim, SJ; Lee, SY; Park, CG; Park, SK; Shin, JS | 1 |
| Chen, H; Jin, WY; Ren, JY | 1 |
| Kim, YS; Lee, SK | 1 |
| Aoki, H; Furutani, A; Hamano, K; Kudo, J; Morikage, N; Nagasawa, A; Onoda, M; Yoshimura, K | 1 |
| Chung, KH; Jung, EJ; Kim, CW | 1 |
7 other study(ies) available for pyrazolanthrone and simvastatin
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection.
Topics: Animals; Anthracenes; Aorta; Cell Division; Cells, Cultured; Chromones; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Flavonoids; Heme Oxygenase (Decyclizing); Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Nitric Oxide; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Simvastatin | 2004 |
The sequential combination of a JNK inhibitor and simvastatin protects porcine islets from peritransplant apoptosis and inflammation.
Topics: Animals; Anthracenes; Anticholesteremic Agents; Apoptosis; Cell Survival; Cells, Cultured; Inflammation Mediators; Islets of Langerhans; Islets of Langerhans Transplantation; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred NOD; Niacinamide; Simvastatin; Swine | 2011 |
[Simvastatin suppress lipopolysaccharides induced upregulation of lipoprotein associated phospholipase A(2) expression in macrophages via inactivation of p38MAPK pathway].
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Anthracenes; Butadienes; Cells, Cultured; Humans; Imidazoles; Lipopolysaccharides; Macrophages; Monocytes; Nitriles; p38 Mitogen-Activated Protein Kinases; Phospholipases A2; Phosphorylation; Pyridines; RNA, Messenger; Simvastatin | 2010 |
Phosphorylation of eIF2α attenuates statin-induced apoptosis by inhibiting the stabilization and translocation of p53 to the mitochondria.
Topics: Animals; Anthracenes; Anticholesteremic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Survival; Cinnamates; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Eukaryotic Initiation Factor-2; Fibrosarcoma; Heat-Shock Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mevalonic Acid; Mice; Mitochondria; Phosphorylation; Polyisoprenyl Phosphates; Protein Transport; RNA Interference; RNA, Small Interfering; Sesquiterpenes; Signal Transduction; Simvastatin; Thiourea; Transcription Factor CHOP; Tumor Suppressor Protein p53 | 2013 |
Inhibitory effect of statins on inflammation-related pathways in human abdominal aortic aneurysm tissue.
Topics: Aged; Aged, 80 and over; Aminoquinolines; Anthracenes; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Chemokine CCL8; Chemokine CXCL5; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; JNK Mitogen-Activated Protein Kinases; Male; Matrix Metalloproteinase 9; Middle Aged; NF-kappa B; Pyrimidines; rac1 GTP-Binding Protein; Signal Transduction; Simvastatin; Tumor Necrosis Factor-alpha | 2015 |
Identification of simvastatin-regulated targets associated with JNK activation in DU145 human prostate cancer cell death signaling.
Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Docetaxel; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein K; Humans; JNK Mitogen-Activated Protein Kinases; Male; Phosphorylation; Prostatic Neoplasms; Proteomics; Signal Transduction; Simvastatin; Taxoids | 2017 |