Compounds > pyrazolanthrone
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pyrazolanthrone and sb 202190

pyrazolanthrone has been researched along with sb 202190 in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's18 (36.00)29.6817
2010's32 (64.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atteridge, CE; Azimioara, MD; Benedetti, MG; Biggs, WH; Carter, TA; Ciceri, P; Edeen, PT; Fabian, MA; Floyd, M; Ford, JM; Galvin, M; Gerlach, JL; Grotzfeld, RM; Herrgard, S; Insko, DE; Insko, MA; Lai, AG; Lélias, JM; Lockhart, DJ; Mehta, SA; Milanov, ZV; Patel, HK; Treiber, DK; Velasco, AM; Wodicka, LM; Zarrinkar, PP1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Chaipech, S; Hayakawa, T; Matsuda, H; Matsumoto, T; Morikawa, T; Muraoka, O; Ninomiya, K; Nomura, Y; Pongpiriyadacha, Y; Sueyoshi, M; Yabe, M; Yoshikawa, M1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A1
Warmka, JK; Wattenberg, EV; Zeliadt, NA1
Baik, EJ; Jung, YS; Kim, CS; Lee, BH; Lee, SH; Moon, CH; Moon, CK; Park, HS; Sohn, S1
Ahn, NS; Cho, SD; Hwang, JW; Jo, EH; Jung, JW; Kang, KS; Kim, SH; Lee, BH; Lee, YS; Park, JS; Yang, SR1
Berk, BC; Che, ZQ; Gao, PJ; Ji, KD; Shen, WL; Yan, C; Yin, M; Zhu, DL1
Batty, S; Chow, EM; Der, SD; Kassam, A; Mogridge, J1
Bowden, GT; Zhang, Y; Zhu, M1
Beers, A; Haas, MJ; Mooradian, AD; Wong, NC1
Hatter, A; Liu, B; Zhang, P1
Clair, DK; García-Cazarín, ML; Piascik, MT; Smith, JL1
Cheng, C; Gao, S; Li, X; Niu, S; Qin, Y; Shen, A; Tao, T; Wang, H1
Fujita, H; Kasai, H; Mitsuhashi, S; Oda, A; Sasaki, T; Urushibara, N; Yoshimizu, M1
Dobreva, ZG; Miteva, LD; Stanilova, SA1
Croons, V; De Meyer, GR; Herman, AG; Martinet, W; Timmermans, JP1
Chang, LS; Chen, KC; Kao, PH; Liu, WH1
Du, X; Geng, W; Lin, N; Shan, Y; Wang, S; Wang, X; Zhao, R1
Jiang, H; Lu, X; Tan, X; Wang, DB; Wei, H; Yang, ZJ; Zhu, R; Zhu, SS1
Do, EK; Kim, JH; Kim, KH; Kim, MY; Shin, SH; Song, HY1
Hu, Y; Shi, Y; Song, Y; Wang, Y; Yang, K; Yu, H1
Aarstad, HJ; Olofsson, J; Olsnes, C1
Aggarwal, S; Rao, RK; Samak, G1
Liedhegner, EA; Mieyal, JJ; Steller, KM1
Barker, G; Lappas, M; Lim, R; Menon, R; Permezel, M; Rice, GE; Riley, C1
Kim, CE; Kim, MH; Kim, SW1
Casagrande, R; Cunha, FQ; Cunha, TM; Ferreira, SH; Mizokami, SS; Pavao-de-Souza, GF; Sanson, JS; Tedeschi, GC; Verri, WA; Zarpelon, AC1
Beyer, EM; MacBeath, G1
Fan, HQ; Li, Y; Wang, JG; Zou, J1
Cho, JE; Cho, SN; Kim, YS; Lee, H; Park, S1
Im, SY; Kim, HA; Kim, KJ; Lee, HK; Seo, KH1
Bian, XW; Chen, GL; Cui, YH; Duan, JJ; Gu, A; Li, TT; Qian, C; Shi, Y; Xin, YH; Xu, C; Yang, XJ; Yu, SC; Zhang, X1
Muthusamy, V; Piva, TJ1
Chen, G; Duan, Z; Li, Y; Liu, J; Nie, X; Wan, C; Xu, G; Zhao, J1
Hahm, ER; Lee, J; Singh, SV1
Chen, G; Han, F; Li, L; Tang, X; Wang, F; Zhou, W1
Anan, H; Iida, H; Inai, T; Kitagawa, N; Minakami, M1
Blank, V; Garcia-Santos, D; Gasiorek, JJ; Hui, ST; Mikhael, M; Ponka, P1
Jiang, X; Wu, Y; Xia, L; Xu, Y; Zhou, Y1
Bauer, D; Darling-Reed, S; Day, A; Flores-Rozas, H; Mazzio, E; Redmon, N; Reuben, JS; Sadrud-Din, S; Soliman, KF; Taka, E1
Fukami, K; Kudo, K; Nakamura, Y; Sawada, M; Uchida, T; Yoneda, A1
Chen, G; Hu, Q; Jiang, S; Li, T; Mao, J; Nie, X; Wang, C; Wang, X; Xu, L; Yang, J; Zhang, Y1
Saito, T; Tang, J1
Wang, J; Zhang, YL; Zhuang, N1
Chen, X; Chen, Y; Hou, X; Lin, X; Su, S; Tian, Y; Zhang, Q1

Other Studies

50 other study(ies) available for pyrazolanthrone and sb 202190

ArticleYear
A small molecule-kinase interaction map for clinical kinase inhibitors.
    Nature biotechnology, 2005, Volume: 23, Issue:3

    Topics: Benzamides; Drug Design; Escherichia coli; Escherichia coli Proteins; Imatinib Mesylate; Microchemistry; Pharmaceutical Preparations; Piperazines; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Pyrimidines

2005
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
The selectivity of protein kinase inhibitors: a further update.
    The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3

    Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera

2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Suppressive effects of coumarins from Mammea siamensis on inducible nitric oxide synthase expression in RAW264.7 cells.
    Bioorganic & medicinal chemistry, 2012, Aug-15, Volume: 20, Issue:16

    Topics: Animals; Cells, Cultured; Coumarins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flowers; Mammea; Mice; Molecular Structure; Nitric Oxide Synthase Type II; Stereoisomerism; Structure-Activity Relationship

2012
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.
    The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2

    Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase

2013
Mitogen activated protein kinases selectively regulate palytoxin-stimulated gene expression in mouse keratinocytes.
    Toxicology and applied pharmacology, 2003, Nov-01, Volume: 192, Issue:3

    Topics: Acrylamides; Animals; Anthracenes; Cell Line, Transformed; Cnidarian Venoms; Collagenases; Dexamethasone; Enzyme Activation; Enzyme Inhibitors; Gene Expression; Imidazoles; Keratinocytes; Matrix Metalloproteinase 13; Mice; Mitogen-Activated Protein Kinases; Pyridines; Signal Transduction

2003
N-nitrosocarbofuran induces apoptosis in mouse brain microvascular endothelial cells (bEnd.3).
    Journal of pharmacological sciences, 2003, Volume: 93, Issue:4

    Topics: Animals; Annexin A5; Anthracenes; Apoptosis; Brain; Carbofuran; Cell Survival; Cells, Cultured; Endothelium, Vascular; Flavonoids; Flow Cytometry; Imidazoles; Mice; Microcirculation; Microscopy, Electron; Mitogen-Activated Protein Kinases; Pesticides; Pyridines; Signal Transduction; Time Factors

2003
The role of p38 MAP kinase and c-Jun N-terminal protein kinase signaling in the differentiation and apoptosis of immortalized neural stem cells.
    Mutation research, 2005, Nov-11, Volume: 579, Issue:1-2

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Cell Differentiation; Cell Line, Transformed; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Stem Cells; Telencephalon; Tumor Suppressor Protein p53

2005
NAD(P)H oxidase-derived reactive oxygen species regulate angiotensin-II induced adventitial fibroblast phenotypic differentiation.
    Biochemical and biophysical research communications, 2006, Jan-06, Volume: 339, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anthracenes; Aorta, Thoracic; Cell Differentiation; Cells, Cultured; Connective Tissue; Fibroblasts; Free Radical Scavengers; Imidazoles; JNK Mitogen-Activated Protein Kinases; Losartan; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oligodeoxyribonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2006
Inhibition of mitogen-activated protein kinase signalling by Bacillus anthracis lethal toxin causes destabilization of interleukin-8 mRNA.
    Cellular microbiology, 2006, Volume: 8, Issue:1

    Topics: 3' Untranslated Regions; Anthracenes; Antigens, Bacterial; Bacillus anthracis; Bacterial Toxins; Butadienes; Cells, Cultured; Endothelial Cells; Humans; Imidazoles; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Nitriles; Promoter Regions, Genetic; Pyridines; RNA Stability; RNA, Messenger; Signal Transduction

2006
Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes.
    Cancer letters, 2006, Dec-08, Volume: 244, Issue:2

    Topics: Acetophenones; Anthracenes; Antioxidants; Benzopyrans; Cells, Cultured; Enzyme Inhibitors; Green Fluorescent Proteins; Humans; Hydroquinones; Imidazoles; JNK Mitogen-Activated Protein Kinases; Keratinocytes; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Protein Kinase C; Pyridines; Response Elements; Rhodamines; Signal Transduction; Staurosporine; Ultraviolet Rays

2006
Inhibition of apolipoprotein AI gene expression by tumor necrosis factor alpha: roles for MEK/ERK and JNK signaling.
    Biochemistry, 2006, Feb-21, Volume: 45, Issue:7

    Topics: Anthracenes; Apolipoprotein A-I; Cell Line, Tumor; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Peptides; Promoter Regions, Genetic; Pyridines; RNA, Small Interfering; Signal Transduction; Sulfones; Transfection; Tumor Necrosis Factor-alpha

2006
Manganese chloride stimulates rat microglia to release hydrogen peroxide.
    Toxicology letters, 2007, Sep-10, Volume: 173, Issue:2

    Topics: Animals; Animals, Newborn; Anthracenes; Butadienes; Cell Line; Cells, Cultured; Chlorides; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Hydrogen Peroxide; Imidazoles; Manganese Compounds; Microglia; NADPH Oxidases; Nitriles; Onium Compounds; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Rats, Inbred F344; Time Factors

2007
The alpha1D-adrenergic receptor induces vascular smooth muscle apoptosis via a p53-dependent mechanism.
    Molecular pharmacology, 2008, Volume: 74, Issue:4

    Topics: Acetophenones; Adrenergic alpha-1 Receptor Antagonists; Anthracenes; Aorta; Apoptosis; Benzothiazoles; Cells, Cultured; Culture Media, Serum-Free; Dioxanes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Humans; Imidazoles; Mitochondria; Muscle, Smooth, Vascular; Phenylephrine; Piperazines; Prazosin; Pyridines; Reactive Oxygen Species; Receptors, Adrenergic, alpha-1; Time Factors; Toluene; Tumor Suppressor Protein p53

2008
Role of mitogen-activated protein kinase cascades in inducible nitric oxide synthase expression by lipopolysaccharide in a rat Schwann cell line.
    Neurochemical research, 2009, Volume: 34, Issue:3

    Topics: Animals; Anthracenes; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Signaling System; Nitric Oxide; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Schwann Cells

2009
JNK and p38 MAPK are independently involved in tributyltin-mediated cell death in rainbow trout (Oncorhynchus mykiss) RTG-2 cells.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2009, Volume: 149, Issue:4

    Topics: Amino Acid Chloromethyl Ketones; Animals; Anthracenes; Apoptosis; Caspase Inhibitors; Caspases; Cell Death; Cells, Cultured; Enzyme Activation; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Oncorhynchus mykiss; p38 Mitogen-Activated Protein Kinases; Pyridines; Trialkyltin Compounds

2009
The inhibition of JNK and p38 MAPKs downregulates IL-10 and differentially affects c-Jun gene expression in human monocytes.
    Immunopharmacology and immunotoxicology, 2009, Volume: 31, Issue:2

    Topics: Anthracenes; Down-Regulation; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Imidazoles; Interleukin-10; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Kinase 4; Monocytes; p38 Mitogen-Activated Protein Kinases; Pyridines; Transcription Factor RelA; Transcription, Genetic

2009
The protein synthesis inhibitor anisomycin induces macrophage apoptosis in rabbit atherosclerotic plaques through p38 mitogen-activated protein kinase.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 329, Issue:3

    Topics: Animals; Anisomycin; Anthracenes; Aorta; Apoptosis; Butadienes; Carotid Arteries; Carotid Stenosis; Cell Line, Tumor; Cells, Cultured; Extracellular Signal-Regulated MAP Kinases; Imidazoles; Macrophages; Macrophages, Alveolar; Mice; Mitogen-Activated Protein Kinases; Myocytes, Smooth Muscle; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Rabbits; Tunica Intima; Tunica Media

2009
Calcium-stimulated mitogen-activated protein kinase activation elicits Bcl-xL downregulation and Bak upregulation in notexin-treated human neuroblastoma SK-N-SH cells.
    Journal of cellular physiology, 2010, Volume: 222, Issue:1

    Topics: Activating Transcription Factor 2; Anthracenes; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-X Protein; Calcium; Caspase 9; Cell Line, Tumor; Down-Regulation; Egtazic Acid; Elapid Venoms; Enzyme Activation; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mitogen-Activated Protein Kinases; Neuroblastoma; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Pyridines; Reactive Oxygen Species; Signal Transduction; Up-Regulation

2010
Protective effect of sulforaphane on human vascular endothelial cells against lipopolysaccharide-induced inflammatory damage.
    Cardiovascular toxicology, 2010, Volume: 10, Issue:2

    Topics: Anisomycin; Anthracenes; Anticarcinogenic Agents; Blotting, Western; Cell Line; Cyclooxygenase 2; Drug Antagonism; Endothelium, Vascular; Enzyme Inhibitors; Heme Oxygenase-1; Humans; Imidazoles; Isothiocyanates; Lipopolysaccharides; Membrane Proteins; Mitogen-Activated Protein Kinases; Neoplasm Proteins; Nitric Oxide Synthase Type II; Phosphorylation; Pyridines; Sulfoxides; Thiocyanates; Vasculitis

2010
Doxorubicin induces apoptosis in H9c2 cardiomyocytes: role of overexpressed eukaryotic translation initiation factor 5A.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:10

    Topics: Animals; Anthracenes; Antibiotics, Antineoplastic; Apoptosis; Calcium; Cardiotoxins; Caspases; Cell Line; Cytochromes c; Doxorubicin; Eukaryotic Translation Initiation Factor 5A; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mitochondria; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Pyridines; Rats; Reactive Oxygen Species; RNA-Binding Proteins; RNA, Small Interfering; Signal Transduction

2010
Platelet-activating factor receptor mediates oxidized low density lipoprotein-induced migration of bone marrow-derived mesenchymal stem cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2010, Volume: 26, Issue:4-5

    Topics: Anthracenes; Becaplermin; Bone Marrow Cells; Butadienes; Cell Movement; Humans; Imidazoles; Lipoproteins, LDL; Mesenchymal Stem Cells; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Platelet Activating Factor; Platelet Membrane Glycoproteins; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyridines; Receptors, G-Protein-Coupled; RNA Interference; RNA, Small Interfering

2010
p,p'-Dichlorodiphenoxydichloroethylene induced apoptosis of Sertoli cells through oxidative stress-mediated p38 MAPK and mitochondrial pathway.
    Toxicology letters, 2011, Apr-10, Volume: 202, Issue:1

    Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Survival; Cytochromes c; Dichlorodiphenyl Dichloroethylene; Gene Expression; Imidazoles; Insecticides; Male; Mitochondria; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sertoli Cells

2011
MAPKs ERK and p38, but not JNK phosphorylation, modulate IL-6 and TNF-α secretion following OK-432 in vitro stimulation of purified human monocytes.
    Scandinavian journal of immunology, 2011, Volume: 74, Issue:2

    Topics: Anthracenes; Antineoplastic Agents; Butadienes; Cells, Cultured; Enzyme Inhibitors; Humans; Imidazoles; Interleukin-6; Leukocytes, Mononuclear; Lipopolysaccharides; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Picibanil; Pyridines; Teichoic Acids; Tumor Necrosis Factor-alpha

2011
ERK is involved in EGF-mediated protection of tight junctions, but not adherens junctions, in acetaldehyde-treated Caco-2 cell monolayers.
    American journal of physiology. Gastrointestinal and liver physiology, 2011, Volume: 301, Issue:1

    Topics: Acetaldehyde; Actins; Adherens Junctions; Anthracenes; beta Catenin; Butadienes; Caco-2 Cells; Cadherins; Claudin-3; Enzyme Inhibitors; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Humans; Imidazoles; Inulin; Membrane Proteins; Nitriles; Occludin; Permeability; Phosphoproteins; Pyridines; Tight Junctions; Zonula Occludens-1 Protein

2011
Levodopa activates apoptosis signaling kinase 1 (ASK1) and promotes apoptosis in a neuronal model: implications for the treatment of Parkinson's disease.
    Chemical research in toxicology, 2011, Oct-17, Volume: 24, Issue:10

    Topics: Anthracenes; Antiparkinson Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Dopaminergic Neurons; Enzyme Inhibitors; Gene Knockdown Techniques; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Levodopa; MAP Kinase Kinase Kinase 5; NF-kappa B; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Parkinson Disease; Pyridines

2011
MAPK and AP-1 proteins are increased in term pre-labour fetal membranes overlying the cervix: regulation of enzymes involved in the degradation of fetal membranes.
    Placenta, 2011, Volume: 32, Issue:12

    Topics: Anthracenes; Butadienes; Cervix Uteri; Extracellular Signal-Regulated MAP Kinases; Extraembryonic Membranes; Female; Gentian Violet; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Nitriles; p38 Mitogen-Activated Protein Kinases; Pregnancy; Pyridines; Quaternary Ammonium Compounds; Transcription Factor AP-1

2011
Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells.
    Biochemical and biophysical research communications, 2011, Dec-02, Volume: 415, Issue:4

    Topics: Anthracenes; Butadienes; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Flavanones; Glucose; Hesperidin; Humans; Hyperglycemia; Imidazoles; Intercellular Adhesion Molecule-1; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Resveratrol; Stilbenes; Up-Regulation; Veins

2011
Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI(3)K and microglia in mice.
    Pharmacology, biochemistry, and behavior, 2012, Volume: 101, Issue:3

    Topics: Acetic Acid; Androstadienes; Animals; Anthracenes; Benzoquinones; Disease Models, Animal; Flavonoids; Imidazoles; Injections, Spinal; Male; MAP Kinase Signaling System; Mice; Microglia; Nociception; Nociceptive Pain; Pain; Pain Measurement; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Spinal Cord; Wortmannin

2012
Cross-talk between receptor tyrosine kinase and tumor necrosis factor-α signaling networks regulates apoptosis but not proliferation.
    Molecular & cellular proteomics : MCP, 2012, Volume: 11, Issue:6

    Topics: Anthracenes; Apoptosis; Cell Proliferation; HEK293 Cells; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Mitogen-Activated Protein Kinases; Phenotype; Protein Interaction Maps; Proto-Oncogene Proteins c-raf; Pyridines; Receptor Cross-Talk; Receptor Protein-Tyrosine Kinases; Signal Transduction; Tumor Necrosis Factor-alpha

2012
Effects of dihydropyridine calcium channel blockers on oxidized low-density lipoprotein induced proliferation and oxidative stress of vascular smooth muscle cells.
    BMC research notes, 2012, Jul-06, Volume: 5

    Topics: Amlodipine; Anthracenes; Butadienes; Calcium Channel Blockers; Cell Proliferation; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipoproteins, LDL; MAP Kinase Signaling System; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitriles; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; Time Factors

2012
c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinase (p38 MAPK) are involved in Mycobacterium tuberculosis-induced expression of Leukotactin-1.
    BMB reports, 2012, Volume: 45, Issue:10

    Topics: Anthracenes; Cell Line, Tumor; Chemokines, CC; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mycobacterium tuberculosis; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction; Tuberculosis; Up-Regulation

2012
PTEN/MAPK pathways play a key role in platelet-activating factor-induced experimental pulmonary tumor metastasis.
    FEBS letters, 2012, Dec-14, Volume: 586, Issue:24

    Topics: Androstadienes; Animals; Anthracenes; Butadienes; Cell Line; Humans; Imidazoles; Lung Neoplasms; MAP Kinase Signaling System; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Nitriles; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Platelet Activating Factor; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyridines; Wortmannin

2012
TGF-β1 enhances tumor-induced angiogenesis via JNK pathway and macrophage infiltration in an improved zebrafish embryo/xenograft glioma model.
    International immunopharmacology, 2013, Volume: 15, Issue:2

    Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Anthracenes; Cell Line, Tumor; Cell Movement; Chromones; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glioma; High-Throughput Screening Assays; Humans; Imidazoles; Macrophages; MAP Kinase Kinase 4; Morpholines; Neovascularization, Pathologic; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Signal Transduction; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays; Zebrafish

2013
UVB-stimulated TNFα release from human melanocyte and melanoma cells is mediated by p38 MAPK.
    International journal of molecular sciences, 2013, Aug-19, Volume: 14, Issue:8

    Topics: Anisomycin; Anthracenes; Cell Line, Tumor; Cell Survival; Humans; Imidazoles; Interleukin-1alpha; MAP Kinase Signaling System; Melanocytes; Melanoma; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Processing, Post-Translational; Pyridines; Sulfasalazine; Tumor Necrosis Factor-alpha

2013
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) induces microglial nitric oxide production and subsequent rat primary cortical neuron apoptosis through p38/JNK MAPK pathway.
    Toxicology, 2013, Oct-04, Volume: 312

    Topics: Animals; Anthracenes; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Microglia; Nitric Oxide; p38 Mitogen-Activated Protein Kinases; Polychlorinated Dibenzodioxins; Pyridines; Rats; Rats, Sprague-Dawley

2013
Role of mitogen-activated protein kinases and Mcl-1 in apoptosis induction by withaferin A in human breast cancer cells.
    Molecular carcinogenesis, 2014, Volume: 53, Issue:11

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Female; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MCF-7 Cells; Myeloid Cell Leukemia Sequence 1 Protein; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; RNA Interference; RNA, Small Interfering; Superoxide Dismutase; Triple Negative Breast Neoplasms; Withanolides

2014
[Effect of MAPK/NF-kappaB signaling pathway on extracellular release of HMGB1 induced by hypoxia in laryngeal Hep-2 carcinoma cells].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2013, Volume: 27, Issue:19

    Topics: Anthracenes; Cell Hypoxia; Cell Line, Tumor; Flavonoids; HMGB1 Protein; Humans; Imidazoles; MAP Kinase Signaling System; NF-kappa B; Protein Kinase Inhibitors; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates

2013
p38 Mitogen-activated protein kinase and c-Jun NH2-terminal protein kinase regulate the accumulation of a tight junction protein, ZO-1, in cell-cell contacts in HaCaT cells.
    Tissue & cell, 2015, Volume: 47, Issue:1

    Topics: Anisomycin; Anthracenes; Cell Communication; Cell Line; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Keratinocytes; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Zonula Occludens-1 Protein

2015
Thioredoxin-interacting protein regulates the differentiation of murine erythroid precursors.
    Experimental hematology, 2015, Volume: 43, Issue:5

    Topics: Animals; Anthracenes; Butadienes; Carrier Proteins; Cell Differentiation; Cell Line; Cell Line, Tumor; Erythroblasts; Erythropoiesis; Extracellular Signal-Regulated MAP Kinases; Gene Expression; Heme; Imidazoles; Immunoblotting; Iron; JNK Mitogen-Activated Protein Kinases; Leukemia, Erythroblastic, Acute; Mice, Inbred C57BL; Mice, Knockout; Nitriles; p38 Mitogen-Activated Protein Kinases; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; Thioredoxins

2015
Icariin induces osteogenic differentiation of bone mesenchymal stem cells in a MAPK-dependent manner.
    Cell proliferation, 2015, Volume: 48, Issue:3

    Topics: Alkaline Phosphatase; Animals; Anthracenes; Bone Density Conservation Agents; Cell Differentiation; Cell Proliferation; Collagen Type I; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Gene Expression Regulation, Developmental; Imidazoles; JNK Mitogen-Activated Protein Kinases; Male; Mesenchymal Stem Cells; Osteoblasts; Osteocalcin; Osteogenesis; Osteopontin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction

2015
Diallyl disulfide inhibits TNFα induced CCL2 release through MAPK/ERK and NF-Kappa-B signaling.
    Cytokine, 2015, Volume: 75, Issue:1

    Topics: Allyl Compounds; Anthracenes; Anticarcinogenic Agents; Butadienes; Cell Line, Tumor; Chemokine CCL2; Disulfides; Garlic; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Macrophages; MAP Kinase Kinase 4; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; NF-kappa B p50 Subunit; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Tumor Necrosis Factor-alpha

2015
Phospholipase C δ1 in macrophages negatively regulates TLR4-induced proinflammatory cytokine production and Fcγ receptor-mediated phagocytosis.
    Advances in biological regulation, 2016, Volume: 61

    Topics: Animals; Anthracenes; Butadienes; Cell Line; Gene Expression Regulation; Imidazoles; Interleukin-1beta; Lipopolysaccharides; Macrophages; Mice; Mice, Knockout; Mutation; Nitriles; p38 Mitogen-Activated Protein Kinases; Phagocytosis; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C delta; Primary Cell Culture; Protein Kinase Inhibitors; Pyridines; Receptors, IgG; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4

2016
Arsenic trioxide mediates HAPI microglia inflammatory response and subsequent neuron apoptosis through p38/JNK MAPK/STAT3 pathway.
    Toxicology and applied pharmacology, 2016, 07-15, Volume: 303

    Topics: Animals; Anthracenes; Apoptosis; Arsenic Trioxide; Arsenicals; Cell Line; Cell Line, Tumor; Humans; Imidazoles; Inflammation; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Microglia; Neurons; Oxides; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Pyridines; Rats; Signal Transduction; STAT3 Transcription Factor

2016
Elucidation on Predominant Pathways Involved in the Differentiation and Mineralization of Odontoblast-Like Cells by Selective Blockade of Mitogen-Activated Protein Kinases.
    BioMed research international, 2018, Volume: 2018

    Topics: Alkaline Phosphatase; Animals; Anthracenes; Biomarkers; Cell Differentiation; Cell Line; Dexamethasone; Down-Regulation; Enzyme Inhibitors; Flavonoids; Imidazoles; Integrin-Binding Sialoprotein; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Odontoblasts; Osteogenesis; Osteopontin; p38 Mitogen-Activated Protein Kinases; Pyridines; Rats; Signal Transduction; Up-Regulation

2018
[Salidroside inhibits inflammatory factor release in BV-2 cells through p38 and JNK pathways].
    Sheng li xue bao : [Acta physiologica Sinica], 2018, Jun-25, Volume: 70, Issue:3

    Topics: Animals; Anthracenes; Apoptosis; Cell Survival; Cells, Cultured; Glucosides; Imidazoles; Inflammation; Interleukin-6; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Microglia; p38 Mitogen-Activated Protein Kinases; Phenols; Phosphorylation; Pyridines; Tumor Necrosis Factor-alpha

2018
The Drug Combination of SB202190 and SP600125 Significantly Inhibit the Growth and Metastasis of Olaparib-resistant Ovarian Cancer Cell.
    Current pharmaceutical biotechnology, 2018, Volume: 19, Issue:6

    Topics: Animals; Anthracenes; Autophagy; Cell Line, Tumor; Cell Proliferation; Drug Combinations; Female; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Ovarian Neoplasms; p38 Mitogen-Activated Protein Kinases; Phthalazines; Piperazines; Protein Kinase Inhibitors; Pyridines

2018