pyrazolanthrone and dinoprostone

Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

Topics: 6-Ketoprostaglandin F1 alpha; Amino Acid Substitution; Angiotensin-Converting Enzyme Inhibitors; Animals; Anthracenes; Aorta; Binding, Competitive; Celecoxib; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; DNA; Endothelial Cells; Endothelium, Vascular; Enzyme Induction; Humans; JNK Mitogen-Activated Protein Kinases; Lung; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mutation, Missense; Oligodeoxyribonucleotides; Peptidyl-Dipeptidase A; Phosphorylation; Promoter Regions, Genetic; Prostaglandin-Endoperoxide Synthases; Prostaglandins I; Protein Processing, Post-Translational; Pyrazoles; Ramipril; Recombinant Fusion Proteins; Signal Transduction; Sulfonamides; Sus scrofa; Thromboxane A2; Transcription Factor AP-1; Transcription, Genetic; Transfection; Umbilical Veins

Topics: Anthracenes; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Enzymologic; Humans; Imidazoles; Interleukin-1; Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; Signal Transduction

Topics: Animals; Anthracenes; Benzazepines; Cell Line; Cyclin-Dependent Kinase 2; Cycloheximide; Cyclooxygenase 2; Dactinomycin; Dinoprostone; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Indoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Macrophages; Mice; Oximes; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-jun; RNA, Messenger; Transcription, Genetic

Topics: Anthracenes; Bone and Bones; Calcium; Calcium Signaling; Cations, Divalent; Cyclooxygenase 2; Dinoprostone; Estrenes; Fibroblasts; Flavonoids; Humans; Imidazoles; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrrolidinones; Receptors, Calcium-Sensing; RNA, Messenger; Type C Phospholipases

Topics: Anthracenes; Caco-2 Cells; Cell Line, Tumor; Cells, Cultured; Cyclooxygenase 2; Dinoprostone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Gene Expression; HT29 Cells; Humans; Imidazoles; Interleukin-8; Intestines; Lipopolysaccharides; Lymphocyte Antigen 96; Mitogen-Activated Protein Kinases; Monocytes; NF-kappa B; Pyridines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Toll-Like Receptor 4; Transfection

Topics: Anthracenes; Cell Line; Chemokines; Chondrocytes; Cyclooxygenase 2; Dinoprostone; Humans; Interleukin-1; MAP Kinase Kinase 4; Nitric Oxide Synthase Type II; Transcription Factor AP-1; Tretinoin

Topics: Animals; Anthracenes; Blotting, Western; Cell Line; Dinoprostone; Forkhead Box Protein O1; Forkhead Transcription Factors; Glucose; Homeodomain Proteins; Insulin; Insulin Secretion; Insulin-Secreting Cells; JNK Mitogen-Activated Protein Kinases; Luciferases; Mice; Mice, Inbred ICR; Microscopy, Fluorescence; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Trans-Activators; Transfection

Topics: Androstadienes; Anthracenes; Cell Line; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Enzyme Inhibitors; Heme Oxygenase-1; Humans; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Metalloporphyrins; NF-kappa B; Nicotine; Nitric Oxide; Nitric Oxide Synthase Type II; Periodontal Ligament; Phosphoinositide-3 Kinase Inhibitors; Protoporphyrins; RNA, Small Interfering; Transfection; Wortmannin

Topics: Acute Lung Injury; Anthracenes; Butadienes; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase 1; Cyclooxygenase 2; Dinoprostone; Endothelial Cells; Humans; Imidazoles; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Lung; MAP Kinase Signaling System; Methyl Ethers; Microvessels; Naphthalenes; Neutrophils; Nitriles; p38 Mitogen-Activated Protein Kinases; Phenylbutyrates; Pyridines; Receptors, Prostaglandin E, EP4 Subtype; Respiratory Distress Syndrome; RNA, Messenger; Thionucleotides

Topics: Anthracenes; Benzamides; Catechin; Cell Line; Cells, Cultured; Connective Tissue Growth Factor; Dinoprostone; Dioxoles; Dose-Response Relationship, Drug; Fibroblasts; Flavonoids; Humans; Imidazoles; Lung; MAP Kinase Kinase 4; Mouth Mucosa; Oral Submucous Fibrosis; p38 Mitogen-Activated Protein Kinases; Protease Inhibitors; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta1

Topics: Adult; Aggregatibacter actinomycetemcomitans; Anthracenes; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacteriological Techniques; Cell Survival; Cells, Cultured; Chitosan; Dinoprostone; Fibroblasts; Gingiva; Humans; Indicators and Reagents; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; MAP Kinase Signaling System; Nanoparticles; NF-kappa B; Periodontal Diseases; Phosphorylation; Porphyromonas gingivalis; Signal Transduction; Tetrazolium Salts; Thiazoles; Transcription Factor RelA

Topics: 3T3 Cells; Animals; Anthracenes; Dinoprostone; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinase 1; Osteoblasts; Osteoprotegerin; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Resveratrol; Sirtuin 1; Stilbenes

Topics: Animals; Anthracenes; Astrocytes; Butadienes; Cyclooxygenase 2; Dinoprostone; Imidazoles; Inflammation Mediators; Lipopolysaccharides; Mice; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase Type II; Nitriles; Primary Cell Culture; Protein Deglycase DJ-1; Pyridines; Tumor Necrosis Factor-alpha