Page last updated: 2024-08-18

pyrazolanthrone and cytochrome c-t

pyrazolanthrone has been researched along with cytochrome c-t in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's24 (63.16)29.6817
2010's14 (36.84)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
An, F; Gajate, C; Mollinedo, F1
Bravo, R; Bruna, A; Caelles, C; Camarasa, J; Camins, A; Canudas, AM; Escubedo, E; Jiménez, A; Jorda, EG; Pallàs, M; Pubill, D; Verdaguer, E1
Debatin, KM; Herr, I; Krilleke, D; Pulte, D; Schulze-Osthoff, K; Ucur, E1
Dent, P; Grant, S; Rahmani, M; Yu, C1
Al-Lamki, R; Bai, L; Bradley, J; Miano, JM; Min, W; Streb, JW; Zhang, R1
Berglund, CM; Budd Haeberlein, SL; Persson, MA; Radesäter, AC1
Eminel, S; Herdegen, T; Klettner, A; Roemer, L; Waetzig, V1
Chang, YC; Hsu, JD; Huang, HP; Wang, CJ; Yang, SF1
Boisvieux-Ulrich, E; Marano, F; Sourdeval, M1
Foo, CP; Lachapelle, G; Mosser, DD; Radicioni, SM; Stankiewicz, AR1
Biswas, KK; Hashiguchi, T; Kawahara, K; Maruyama, I; Sarker, KP; Tancharoen, S; Tancharon, S1
Hiura, T; Ishikawa, M; Kanno, S; Kimura, K; Ohtake, T; Osanai, Y; Takeshita, M; Tomizawa, A; Ujibe, M; Uwai, K1
Barna, G; Hernlund, E; Ihrlund, LS; Linder, S; Panaretakis, T; Sabapathy, K; Shoshan, MC; Viktorsson, K1
Alemán-Lazarini, L; Arce-Popoca, E; Cabrales-Romero, Mdel P; Fattel-Fazenda, S; Márquez-Rosado, L; Trejo-Solís, C; Villa-Treviño, S1
Guan, QH; Liu, XM; Pei, DS; Wang, XT; Xu, TL; Zhang, GY1
Baile, CA; Della-Fera, MA; Yang, JY1
Huang, L; Li, F; Lu, Y; Ma, D; Meng, L; Wang, S; Xing, H; Xu, G; Zhou, J; Zhu, H1
Beerheide, W; Boelsterli, UA; Latchoumycandane, C; Sattabongkot, J; Seah, QM; Tan, RC1
Aranbayeva, Z; Dickinson, D; Digumarthi, H; Hsu, S; Lewis, J; Messer, R; Osaki, T; Qin, H; Schuster, GS; Wataha, J; Yamamoto, T1
Nguyen, TV; Pike, CJ; Yao, M1
Aizu-Yokota, E; Kasahara, T; Murakami, Y; Ohta, S; Sonoda, Y1
Chen, M; Gao, X; Liu, L; Xing, D; Zhang, L1
Hou, Q1
Cheng, JL; Li, H; Li, QS; Peng, CH; Shi, S; Tian, Y; Xu, CQ; Xu, M; Zhang, L1
Jiang, H; Lu, X; Tan, X; Wang, DB; Wei, H; Yang, ZJ; Zhu, R; Zhu, SS1
Agrawal, M; Bala Bhaskar, AS; Gupta, N; Lakshmana Rao, PV; Ravindran, J1
Hu, Y; Shi, Y; Song, Y; Wang, Y; Yang, K; Yu, H1
Balazs, L; Bezawada, L; Ghosh, MC; Gorantla, VK; Luellen, C; Makena, PS; Parthasarathi, K; Sinclair, SE; Waters, CM1
Du Pasquier, D; Dupré, A; Jessus, C1
Fu, G; Qiu, F; Xu, S; Yu, L; Zhao, Y1
Kim, HR; Kim, JI; Lee, MS; Park, NG; Utsuki, T1
Liu, X; Wang, J; Wang, Y; Wu, W; Xiao, H; Yuan, L1
Cao, Q; Cao, X; Du, S; Kong, D; Que, J; Sui, T1
Chen, JY; Qin, LP; Su, L; Zhang, H; Zhang, L1
Baek, MW; Chung, HJ; Jeong, YJ; Jung, JY; Kim, GM; Kim, SH; Kim, WJ; Park, HJ; Seong, KJ1
Cao, S; Guo, W; Li, J; Yan, B; Zhang, G; Zhang, S; Zhao, Y1
Chen, JX; Ding, KF; Du, CJ; Gao, F; Hu, SM; Li, SJ; Li, Y; Mao, XW; Miyamoto, H; Wen, JM; Zhang, N; Zhang, SG1
Geng, C; Wei, J; Wu, C1

Other Studies

38 other study(ies) available for pyrazolanthrone and cytochrome c-t

ArticleYear
Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:4

    Topics: Anthracenes; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carrier Proteins; Caspase 3; Caspases; Cell Line, Tumor; Cells, Cultured; Curcumin; Cytochromes c; Depsipeptides; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; fas Receptor; Flow Cytometry; Glutathione Transferase; Hepatocytes; HL-60 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia; MAP Kinase Kinase 4; Microscopy, Fluorescence; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Peptides, Cyclic; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Time Factors; Tumor Cells, Cultured

2003
Neuroprotective action of flavopiridol, a cyclin-dependent kinase inhibitor, in colchicine-induced apoptosis.
    Neuropharmacology, 2003, Volume: 45, Issue:5

    Topics: Amino Acid Chloromethyl Ketones; Animals; Animals, Newborn; Anthracenes; Anti-Bacterial Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Bromodeoxyuridine; Carrier Proteins; Caspase 3; Caspases; CDC2-CDC28 Kinases; Cell Count; Cell Survival; Cells, Cultured; Cerebellum; Chromatin; Colchicine; Cyclin E; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase 5; Cyclin-Dependent Kinases; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Flavonoids; Flow Cytometry; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Kainic Acid; MAP Kinase Kinase 4; Microtubules; Minocycline; Mitogen-Activated Protein Kinase Kinases; Neurons; Neuroprotective Agents; Piperidines; Purines; Rats; Rats, Sprague-Dawley; Roscovitine; Time Factors; Tubulin

2003
Inhibition of JNK signaling diminishes early but not late cellular stress-induced apoptosis.
    International journal of cancer, 2003, Nov-20, Volume: 107, Issue:4

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Caspases; Cisplatin; Cytochromes c; Doxorubicin; Enzyme Activation; Fas Ligand Protein; fas Receptor; Genes, Dominant; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; MAP Kinase Kinase 4; Membrane Glycoproteins; Membrane Potentials; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Oxidative Stress; Phosphatidylserines; Poly(ADP-ribose) Polymerases; Signal Transduction

2003
The hierarchical relationship between MAPK signaling and ROS generation in human leukemia cells undergoing apoptosis in response to the proteasome inhibitor Bortezomib.
    Experimental cell research, 2004, May-01, Volume: 295, Issue:2

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Caspases; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia; MAP Kinase Signaling System; Membrane Potentials; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Protease Inhibitors; Pyrazines; Pyridines; Reactive Oxygen Species; Signal Transduction; U937 Cells

2004
Thioredoxin-2 inhibits mitochondria-located ASK1-mediated apoptosis in a JNK-independent manner.
    Circulation research, 2004, Jun-11, Volume: 94, Issue:11

    Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Cytochromes c; Cytoplasm; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; Membrane Proteins; Mitochondria; Protein Interaction Mapping; Protein Structure, Tertiary; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Thioredoxins; Tumor Necrosis Factor-alpha

2004
UV-induced apoptosis in SH-SY5Y cells: contribution to apoptosis by JNK signaling and cytochrome c.
    Journal of neuroscience research, 2004, Nov-15, Volume: 78, Issue:4

    Topics: Anthracenes; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Mitochondria; Neuroblastoma; Proto-Oncogene Proteins c-jun; Time Factors; Ultraviolet Rays

2004
JNK2 translocates to the mitochondria and mediates cytochrome c release in PC12 cells in response to 6-hydroxydopamine.
    The Journal of biological chemistry, 2004, Dec-31, Volume: 279, Issue:53

    Topics: Animals; Anthracenes; Apoptosis; Blotting, Western; Caspase 3; Caspases; Cell Nucleus; Cytochromes c; Cytoplasm; Databases as Topic; DNA, Complementary; Genes, Dominant; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitochondria; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinase Kinases; Oxidopamine; PC12 Cells; Phosphorylation; Plasmids; Poly(ADP-ribose) Polymerases; Protein Isoforms; Protein Transport; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Time Factors; Transfection; Trypan Blue

2004
Hibiscus anthocyanins rich extract-induced apoptotic cell death in human promyelocytic leukemia cells.
    Toxicology and applied pharmacology, 2005, Jun-15, Volume: 205, Issue:3

    Topics: Androstadienes; Anthocyanins; Anthracenes; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; Caspases; Cell Survival; Cytochromes c; DNA, Mitochondrial; Dose-Response Relationship, Drug; Fas Ligand Protein; Flavonoids; Flowers; Hibiscus; HL-60 Cells; Humans; Imidazoles; Membrane Glycoproteins; p38 Mitogen-Activated Protein Kinases; Plant Extracts; Proto-Oncogene Proteins c-jun; Pyridines; RNA, Messenger; Time Factors; Wortmannin

2005
CD437, a synthetic retinoid, induces apoptosis in human respiratory epithelial cells via caspase-independent mitochondrial and caspase-8-dependent pathways both up-regulated by JNK signaling pathway.
    Experimental cell research, 2005, Jul-01, Volume: 307, Issue:1

    Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 8; Caspases; Cell Culture Techniques; Cell Line; Cell Nucleus; Cell Survival; Cytochromes c; Cytosol; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Mitochondria; Models, Biological; Olfactory Mucosa; Proto-Oncogene Proteins c-bcl-2; Respiratory Mucosa; Retinoids; S Phase; Signal Transduction; Up-Regulation

2005
Hsp70 inhibits heat-induced apoptosis upstream of mitochondria by preventing Bax translocation.
    The Journal of biological chemistry, 2005, Nov-18, Volume: 280, Issue:46

    Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspases; Cell Death; Cell Line, Tumor; Cell Membrane; Cross-Linking Reagents; Cytochromes c; Cytosol; Dimerization; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Genes, Dominant; HeLa Cells; Hot Temperature; HSP70 Heat-Shock Proteins; Humans; Immunoprecipitation; MAP Kinase Kinase 4; Microscopy, Fluorescence; Mitochondria; Mutation; Protein Binding; Protein Conformation; Protein Transport; Proto-Oncogene Proteins c-bcl-2; T-Lymphocytes; Temperature; Tetracycline; Time Factors

2005
Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt.
    FEBS letters, 2006, Jan-23, Volume: 580, Issue:2

    Topics: Alkaloids; Animals; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Benzylisoquinolines; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cell Line, Tumor; Collagen Type XI; Cytochromes c; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species

2006
Trimidox induces apoptosis via cytochrome c release in NALM-6 human B cell leukaemia cells.
    Basic & clinical pharmacology & toxicology, 2006, Volume: 98, Issue:1

    Topics: Anthracenes; Apoptosis; Benzamidines; Butadienes; Caspase 3; Caspase 9; Caspases; Cell Line, Tumor; Cytochromes c; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; Leukemia, B-Cell; Nitriles; Oligopeptides; Ribonucleotide Reductases; Signal Transduction; Time Factors

2006
Two distinct steps of Bak regulation during apoptotic stress signaling: different roles of MEKK1 and JNK1.
    Experimental cell research, 2006, May-15, Volume: 312, Issue:9

    Topics: Animals; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; Bcl-2-Like Protein 11; BH3 Interacting Domain Death Agonist Protein; Caspase 3; Caspases; Cell Line, Tumor; Cisplatin; Cytochromes c; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 1; Membrane Proteins; Mice; Mitogen-Activated Protein Kinase 8; Models, Biological; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins; Signal Transduction; Sorbitol; Transfection

2006
S-adenosyl-methionine decreases ethanol-induced apoptosis in primary hepatocyte cultures by a c-Jun N-terminal kinase activity-independent mechanism.
    World journal of gastroenterology, 2006, Mar-28, Volume: 12, Issue:12

    Topics: Animals; Anthracenes; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Caspase 3; Caspases; Cells, Cultured; Cytochromes c; Ethanol; Glutathione; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Male; Mitochondria; Rats; Rats, Inbred F344; Reactive Oxygen Species; S-Adenosylmethionine; Signal Transduction

2006
Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis.
    Brain research, 2006, May-30, Volume: 1092, Issue:1

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Brain Ischemia; Caspase 3; Caspases; Cerebral Infarction; Cytochromes c; Enzyme Inhibitors; Fas Ligand Protein; Hippocampus; JNK Mitogen-Activated Protein Kinases; Male; Membrane Glycoproteins; Nerve Degeneration; Neuroprotective Agents; Proto-Oncogene Proteins c-jun; Rats; Rats, Sprague-Dawley; Signal Transduction; Tumor Necrosis Factors

2006
Esculetin induces mitochondria-mediated apoptosis in 3T3-L1 adipocytes.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:8

    Topics: 3T3-L1 Cells; Animals; Anthracenes; Apoptosis; Caspase 3; Cell Survival; Cytochromes c; JNK Mitogen-Activated Protein Kinases; Mice; Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Umbelliferones

2006
Essential role of c-Jun-NH2-terminal kinase on synergy induction of apoptosis by TRAIL plus ADM in ADM resistant MCF-7/ADM cells.
    Apoptosis : an international journal on programmed cell death, 2006, Volume: 11, Issue:7

    Topics: Anthracenes; Antibiotics, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Breast Neoplasms; Caspase 8; Caspase 9; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cytochromes c; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Synergism; Female; Flow Cytometry; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Glycoproteins; Mitochondria; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha

2006
Leflunomide or A77 1726 protect from acetaminophen-induced cell injury through inhibition of JNK-mediated mitochondrial permeability transition in immortalized human hepatocytes.
    Toxicology and applied pharmacology, 2006, Nov-15, Volume: 217, Issue:1

    Topics: Acetaminophen; Aniline Compounds; Anthracenes; Antirheumatic Agents; Caspase 3; Cell Death; Cell Line; Crotonates; Cytochromes c; Dose-Response Relationship, Drug; Enzyme Activation; Glutathione; Hepatocytes; Humans; Hydroxybutyrates; Isoxazoles; JNK Mitogen-Activated Protein Kinases; Leflunomide; Mitochondria, Liver; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Nitriles; Phosphorylation; Protein Carbonylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Toluidines

2006
EGCG-targeted p57/KIP2 reduces tumorigenicity of oral carcinoma cells: role of c-Jun N-terminal kinase.
    Toxicology and applied pharmacology, 2007, Nov-01, Volume: 224, Issue:3

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Catechin; Cell Line; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p57; Cytochromes c; Disease-Free Survival; Enzyme Inhibitors; Female; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Nude; Mouth Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Signal Transduction; Transfection; Xenograft Model Antitumor Assays

2007
Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Feb-07, Volume: 27, Issue:6

    Topics: Amyloid beta-Peptides; Animals; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Carrier Proteins; Cerebral Cortex; Cytochromes c; Enzyme Activation; Estradiol; Estrogen Receptor Modulators; Fulvestrant; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Membrane Proteins; Mitochondria; Mitochondrial Proteins; Nerve Tissue Proteins; Neurons; Neuroprotective Agents; Peptide Fragments; Protein Kinase Inhibitors; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Transfection

2007
Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2.
    Journal of biochemistry, 2007, Volume: 141, Issue:3

    Topics: Animals; Anthracenes; Apoptosis; bcl-X Protein; Brefeldin A; Caspase 2; Caspase 9; Cytochromes c; Endoplasmic Reticulum; Enzyme Activation; Imidazoles; JNK Mitogen-Activated Protein Kinases; NFI Transcription Factors; PC12 Cells; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Transfection

2007
TNFalpha induces apoptosis through JNK/Bax-dependent pathway in differentiated, but not naïve PC12 cells.
    Cell cycle (Georgetown, Tex.), 2007, Jun-15, Volume: 6, Issue:12

    Topics: Animals; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Bcl-2-Like Protein 11; Cysteine Proteinase Inhibitors; Cytochromes c; MAP Kinase Kinase 4; Membrane Proteins; Microscopy, Confocal; Mitochondria; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Oligopeptides; PC12 Cells; Protein Transport; Proto-Oncogene Proteins; Rats; RNA, Messenger; Signal Transduction; Tumor Necrosis Factor-alpha

2007
[Effect of staurosporine induced apoptosis of MCF7/GFP-Bax stable cell line on Bax translocation from cytosol into mitochondria].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2008, Volume: 43, Issue:4

    Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cytochromes c; Cytosol; Humans; MAP Kinase Kinase 4; Membrane Potentials; Mitochondria; Protein Transport; Staurosporine

2008
Anti-apoptotic action of hydrogen sulfide is associated with early JNK inhibition.
    Cell biology international, 2009, Volume: 33, Issue:10

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Cells, Cultured; Cytochromes c; Cytoprotection; Hydrogen Sulfide; JNK Mitogen-Activated Protein Kinases; Myocytes, Cardiac; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar

2009
Doxorubicin induces apoptosis in H9c2 cardiomyocytes: role of overexpressed eukaryotic translation initiation factor 5A.
    Biological & pharmaceutical bulletin, 2010, Volume: 33, Issue:10

    Topics: Animals; Anthracenes; Antibiotics, Antineoplastic; Apoptosis; Calcium; Cardiotoxins; Caspases; Cell Line; Cytochromes c; Doxorubicin; Eukaryotic Translation Initiation Factor 5A; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mitochondria; Myocytes, Cardiac; p38 Mitogen-Activated Protein Kinases; Peptide Initiation Factors; Pyridines; Rats; Reactive Oxygen Species; RNA-Binding Proteins; RNA, Small Interfering; Signal Transduction

2010
Modulation of ROS/MAPK signaling pathways by okadaic acid leads to cell death via, mitochondrial mediated caspase-dependent mechanism.
    Apoptosis : an international journal on programmed cell death, 2011, Volume: 16, Issue:2

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Apoptosis Inducing Factor; Blotting, Western; Caspase 3; Caspase 7; Caspase 9; Cell Line, Tumor; Cyclosporins; Cytochromes c; DNA Damage; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glutathione; Humans; Imidazoles; Immunoblotting; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Poly(ADP-ribose) Polymerases; Pyridines; Reactive Oxygen Species; U937 Cells

2011
p,p'-Dichlorodiphenoxydichloroethylene induced apoptosis of Sertoli cells through oxidative stress-mediated p38 MAPK and mitochondrial pathway.
    Toxicology letters, 2011, Apr-10, Volume: 202, Issue:1

    Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Cell Survival; Cytochromes c; Dichlorodiphenyl Dichloroethylene; Gene Expression; Imidazoles; Insecticides; Male; Mitochondria; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Proteins c-bcl-2; Pyridines; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sertoli Cells

2011
Lung injury caused by high tidal volume mechanical ventilation and hyperoxia is dependent on oxidant-mediated c-Jun NH2-terminal kinase activation.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:5

    Topics: Acetylcysteine; Animals; Anthracenes; Apoptosis; Caspase 3; Caspase Inhibitors; Cell Line; Cytochromes c; Epithelial Cells; Hyperoxia; JNK Mitogen-Activated Protein Kinases; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mitochondria; Oxidants; Oxidative Stress; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Respiration, Artificial; Tidal Volume

2011
Unfertilized Xenopus eggs die by Bad-dependent apoptosis under the control of Cdk1 and JNK.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Animals; Anthracenes; Apoptosis; bcl-Associated Death Protein; Blotting, Western; Butadienes; Caspases; CDC2 Protein Kinase; Cyclin B; Cytochromes c; Female; JNK Mitogen-Activated Protein Kinases; Mitochondria; Mitogen-Activated Protein Kinase 3; Models, Biological; Molecular Sequence Data; Nitriles; Oocytes; Ovum; Phosphorylation; Progesterone; Time Factors; Xenopus laevis; Xenopus Proteins

2011
Thymosin β4 activates integrin-linked kinase and decreases endothelial progenitor cells apoptosis under serum deprivation.
    Journal of cellular physiology, 2011, Volume: 226, Issue:11

    Topics: Androstadienes; Annexin A5; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Proliferation; Cell Survival; Cells, Cultured; Chromones; Culture Media, Serum-Free; Cytochromes c; Endothelial Cells; Enzyme Inhibitors; Humans; Morpholines; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stem Cells; Thymosin; Wortmannin

2011
Cytoprotective effects of phlorofucofuroeckol A isolated from Ecklonia stolonifera against tacrine-treated HepG2 cells.
    Fitoterapia, 2012, Volume: 83, Issue:6

    Topics: Anthracenes; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Benzofurans; Caspase 3; Caspase 8; Cholinesterase Inhibitors; Cytochromes c; Cytosol; Dioxins; Dose-Response Relationship, Drug; Fas Ligand Protein; fas Receptor; Hep G2 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Mitochondria; Oxidative Stress; Phaeophyceae; Phosphorylation; Plant Extracts; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Tacrine

2012
MAPK signaling pathways regulate mitochondrial-mediated apoptosis induced by isoorientin in human hepatoblastoma cancer cells.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 53

    Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Caspase 3; Cell Survival; Cytochromes c; Electrophoresis, Polyacrylamide Gel; Hep G2 Cells; Hepatoblastoma; Humans; Luteolin; MAP Kinase Signaling System; Mitochondria; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Plant Extracts; Reactive Oxygen Species

2013
Effect of FK506 in reducing scar formation by inducing fibroblast apoptosis after sciatic nerve injury in rats.
    Cell death & disease, 2013, Mar-07, Volume: 4

    Topics: Anastomosis, Surgical; Animals; Anthracenes; Apoptosis; Caspase 3; Cell Proliferation; Cells, Cultured; Cicatrix; Cytochromes c; Cytoprotection; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Flavonoids; Immunosuppressive Agents; JNK Mitogen-Activated Protein Kinases; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Tacrolimus

2013
Triggering of p38 MAPK and JNK signaling is important for oleanolic acid-induced apoptosis via the mitochondrial death pathway in hypertrophic scar fibroblasts.
    Phytotherapy research : PTR, 2014, Volume: 28, Issue:10

    Topics: Anthracenes; Apoptosis; Apoptotic Protease-Activating Factor 1; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line; Cicatrix, Hypertrophic; Cytochromes c; Fibroblasts; Humans; Imidazoles; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Oleanolic Acid; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyridines; Signal Transduction

2014
Nitric oxide induces apoptosis in human gingival fibroblast through mitochondria-dependent pathway and JNK activation.
    International endodontic journal, 2015, Volume: 48, Issue:3

    Topics: Anthracenes; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Butadienes; Cell Survival; Cells, Cultured; Cytochromes c; Enzyme Inhibitors; Fibroblasts; Gingiva; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Membrane Potentials; Mitochondria; Nitric Oxide; Nitriles; Nitroprusside; Pyridines; Signal Transduction

2015
Myocardial protective effects of a c-Jun N-terminal kinase inhibitor in rats with brain death.
    Journal of cellular and molecular medicine, 2016, Volume: 20, Issue:7

    Topics: Animals; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Brain Death; Cardiotonic Agents; Caspase 3; Cytochromes c; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; Male; Mitochondria; Myocardium; Phosphorylation; Protein Kinase Inhibitors; Rats, Sprague-Dawley; RNA, Messenger

2016
Thymol inhibits bladder cancer cell proliferation via inducing cell cycle arrest and apoptosis.
    Biochemical and biophysical research communications, 2017, 09-16, Volume: 491, Issue:2

    Topics: Acetylcysteine; Anthracenes; Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 9; Cell Line, Transformed; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Epithelial Cells; Free Radical Scavengers; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Pyridines; Reactive Oxygen Species; Thymol; Urothelium

2017
Mammalian STE20-like Kinase 1 Knockdown Attenuates TNFα-Mediated Neurodegenerative Disease by Repressing the JNK Pathway and Mitochondrial Stress.
    Neurochemical research, 2019, Volume: 44, Issue:7

    Topics: Animals; Anthracenes; Apoptosis; Cell Line, Tumor; Cytochromes c; Dose-Response Relationship, Drug; Gene Knockdown Techniques; Inflammation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Reactive Oxygen Species; Tumor Necrosis Factor-alpha

2019