Page last updated: 2024-08-18

pyrazolanthrone and curcumin

pyrazolanthrone has been researched along with curcumin in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (35.00)29.6817
2010's12 (60.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Chokchaisiri, R; Chuprajob, T; Lin, Y; Lu, X; Shen, X; Sornkaew, N; Suksamrarn, A; Wang, F; Wang, P; Wongkrajang, K; Yang, L; Yang, N; Zhang, G; Zhou, Z1
An, F; Gajate, C; Mollinedo, F1
Campbell, FC; Collett, GP1
Kang, S; Kwon, KS; Suh, HW1
Fukumori, S; Hashimoto, Y; Murata, T; Taguchi, M1
Binion, DG; Floer, M; Manley, S; Nelson, VM; Rafiee, P; Shaker, R; Wellner, M1
Chen, HM; Cheng, SJ; Chiang, CP; Deng, YT; Kuo, MY1
Chen, YF; Li, ST; Li, Y; Na, LX; Sun, CH; Wang, SL; Wen, Y1
Kaji, T; Shinkai, Y; Yamamoto, C1
Bai, QX; Zhang, XY1
Chang, CH; Chen, HT; Tang, CH; Tsou, HK; Yang, WY1
Ahmad, R; Chaudry, A; El Mabrouk, M; Sylvester, J; Zafarullah, M1
Chang, HH; Chang, JZ; Deng, YT; Kuo, MY; Liu, CM; Yang, WH1
Bai, PS; Chen, NZ; Da, R; Kong, Y; Ma, JQ; Ma, LQ; Nan, KJ; Qi, XG; Sun, H; Zhao, RM1
Cai, L; Li, X; Liang, G; Liu, Q; Pan, Y; Ren, L; Tang, L; Wang, J; Wang, Y; Zhang, X; Zhao, Y1
Cai, L; Liang, G; Liu, Q; Liu, Y; Miao, X; Sun, J; Tan, Y; Wang, Y; Zheng, Y; Zhou, S1
Giri, RK; Sidhar, H1
Chen, Y; Geng, S; Jiang, Y; Li, X; Li, Y; Meng, Y; Wang, S; Wang, X; Wu, J; Xie, C; Yang, X; Zhong, C; Zhu, J; Zhu, W1
Anuchapreeda, S; Chiampanichayakul, S; Krig, SR; Rungrojsakul, M; Tima, S1
Bai, B; Guo, L; Liang, G; Shan, X; Xiao, Z; Xu, F; Zhang, B; Zhang, Y; Zhao, Y; Zhu, X1

Other Studies

20 other study(ies) available for pyrazolanthrone and curcumin

ArticleYear
Discovery of diarylheptanoids that activate α7 nAchR-JAK2-STAT3 signaling in macrophages with anti-inflammatory activity in vitro and in vivo.
    Bioorganic & medicinal chemistry, 2022, 07-15, Volume: 66

    Topics: Animals; Anti-Inflammatory Agents; Diarylheptanoids; Janus Kinase 2; Lipopolysaccharides; Macrophages; Mice; NF-kappa B; Sepsis; STAT3 Transcription Factor

2022
Rapid and selective apoptosis in human leukemic cells induced by Aplidine through a Fas/CD95- and mitochondrial-mediated mechanism.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:4

    Topics: Anthracenes; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Blotting, Western; Carrier Proteins; Caspase 3; Caspases; Cell Line, Tumor; Cells, Cultured; Curcumin; Cytochromes c; Depsipeptides; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; fas Receptor; Flow Cytometry; Glutathione Transferase; Hepatocytes; HL-60 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia; MAP Kinase Kinase 4; Microscopy, Fluorescence; Mitochondria; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Peptides, Cyclic; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Time Factors; Tumor Cells, Cultured

2003
Curcumin induces c-jun N-terminal kinase-dependent apoptosis in HCT116 human colon cancer cells.
    Carcinogenesis, 2004, Volume: 25, Issue:11

    Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Curcumin; Enzyme Inhibitors; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; NF-kappa B; Pyridines; Signal Transduction

2004
Curcumin attenuates glutamate-induced HT22 cell death by suppressing MAP kinase signaling.
    Molecular and cellular biochemistry, 2007, Volume: 298, Issue:1-2

    Topics: Animals; Anthracenes; Antioxidants; Cell Death; Cell Line; Curcumin; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Glutamic Acid; Glutathione; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; Neuroprotective Agents; Oxidative Stress; Phosphorylation; Reactive Oxygen Species; Transcription Factor AP-1

2007
Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells.
    Drug metabolism and pharmacokinetics, 2007, Volume: 22, Issue:5

    Topics: Anthracenes; Calcitriol; Cell Line; Curcumin; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Hydroxylation; Intestinal Mucosa; JNK Mitogen-Activated Protein Kinases; Lithocholic Acid; Molecular Structure; Protein Kinase Inhibitors; Receptors, Calcitriol; RNA, Messenger; Staurosporine; Time Factors; Vitamin D

2007
Effect of curcumin on acidic pH-induced expression of IL-6 and IL-8 in human esophageal epithelial cells (HET-1A): role of PKC, MAPKs, and NF-kappaB.
    American journal of physiology. Gastrointestinal and liver physiology, 2009, Volume: 296, Issue:2

    Topics: Anthracenes; Anti-Inflammatory Agents; Benzophenanthridines; Cell Line; Curcumin; Enzyme Activation; Epithelial Cells; Esophagus; Flavonoids; Humans; Hydrogen-Ion Concentration; Imidazoles; Interleukin-6; Interleukin-8; Mitogen-Activated Protein Kinases; Mucous Membrane; NF-kappa B; Peptides; Protein Kinase C; Protein Kinase Inhibitors; Pyridines; Signal Transduction; Telomerase; Time Factors; Transcription, Genetic; Up-Regulation

2009
Arecoline-stimulated connective tissue growth factor production in human buccal mucosal fibroblasts: Modulation by curcumin.
    Oral oncology, 2009, Volume: 45, Issue:9

    Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Arecoline; Cheek; Cholinergic Agonists; Connective Tissue Growth Factor; Curcumin; Endothelial Cells; Epithelial Cells; Fibroblasts; Flavonoids; Humans; Imidazoles; Mouth Mucosa; Nitriles; Oral Submucous Fibrosis; Pyridines; Sulfones

2009
Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway.
    Biomedical and environmental sciences : BES, 2009, Volume: 22, Issue:1

    Topics: 3T3-L1 Cells; Animals; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Curcumin; Glucose; Insulin; Insulin Resistance; Interleukin-6; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice; NF-kappa B; Palmitates; Protein Kinase Inhibitors; Tumor Necrosis Factor-alpha; Up-Regulation

2009
Lead induces the expression of endoplasmic reticulum chaperones GRP78 and GRP94 in vascular endothelial cells via the JNK-AP-1 pathway.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 114, Issue:2

    Topics: Animals; Anthracenes; Aorta; Cattle; Curcumin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endothelium, Vascular; Environmental Pollutants; Gene Silencing; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; Lead; Membrane Proteins; Nitrates; Phosphorylation; Transcription Factor AP-1

2010
Curcumin enhances cytotoxic effects of bortezomib in human multiple myeloma H929 cells: potential roles of NF-κB/JNK.
    International journal of molecular sciences, 2012, Volume: 13, Issue:4

    Topics: Anthracenes; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Curcumin; Drug Synergism; Extracellular Signal-Regulated MAP Kinases; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Multiple Myeloma; p38 Mitogen-Activated Protein Kinases; Pyrazines; Transcription Factor RelA

2012
Apoptosis signal-regulating kinase 1 is mediated in TNF-α-induced CCL2 expression in human synovial fibroblasts.
    Journal of cellular biochemistry, 2012, Volume: 113, Issue:11

    Topics: Anthracenes; Antibodies; Bursa, Synovial; Chemokine CCL2; Curcumin; Dose-Response Relationship, Drug; Fibroblasts; Gene Expression Regulation; Genes, Reporter; Humans; Imidazoles; Luciferases; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 5; Osteoarthritis; p38 Mitogen-Activated Protein Kinases; Primary Cell Culture; Pyridines; Receptors, Tumor Necrosis Factor, Type I; Signal Transduction; Thioredoxins; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2012
Interleukin-1 induction of aggrecanase gene expression in human articular chondrocytes is mediated by mitogen-activated protein kinases.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 30, Issue:3

    Topics: Anthracenes; Butadienes; Cartilage, Articular; Cells, Cultured; Chondrocytes; Curcumin; Endopeptidases; Gene Expression Regulation; Humans; Imidazoles; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Lipoxygenases; Masoprocol; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; NF-kappa B; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Pyrrolidines; RNA, Messenger; Thiocarbamates; Transcription Factor AP-1

2012
Curcumin inhibits TGFβ1-induced CCN2 via Src, JNK, and Smad3 in gingiva.
    Journal of dental research, 2013, Volume: 92, Issue:7

    Topics: Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Catechin; Cell Culture Techniques; Cell Movement; Cells, Cultured; Connective Tissue Growth Factor; Curcumin; Enzyme Inhibitors; Fibroblasts; Flavonoids; Gingiva; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Lovastatin; MAP Kinase Kinase 4; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Signal Transduction; Smad3 Protein; src-Family Kinases; Transforming Growth Factor beta1

2013
Helicobacter pylori promotes invasion and metastasis of gastric cancer cells through activation of AP-1 and up-regulation of CACUL1.
    The international journal of biochemistry & cell biology, 2013, Volume: 45, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Animals; Anthracenes; Cell Line, Tumor; Cullin Proteins; Curcumin; Female; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Helicobacter pylori; Humans; Male; Matrix Metalloproteinase 9; Mice; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-fos; Stomach; Stomach Neoplasms; Transcription Factor AP-1; Transcriptional Activation; Up-Regulation; Young Adult

2013
Targeting JNK by a new curcumin analog to inhibit NF-kB-mediated expression of cell adhesion molecules attenuates renal macrophage infiltration and injury in diabetic mice.
    PloS one, 2013, Volume: 8, Issue:11

    Topics: Animals; Anthracenes; Cell Line; Chemokine CCL2; Curcumin; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enzyme Inhibitors; Gene Expression Regulation; Intercellular Adhesion Molecule-1; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mice; NF-kappa B; Phosphorylation; Vascular Cell Adhesion Molecule-1

2013
Inhibition of JNK by compound C66 prevents pathological changes of the aorta in STZ-induced diabetes.
    Journal of cellular and molecular medicine, 2014, Volume: 18, Issue:6

    Topics: Animals; Anthracenes; Anti-Inflammatory Agents, Non-Steroidal; Aorta; Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Curcumin; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; JNK Mitogen-Activated Protein Kinases; Male; Mast Cells; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; Phosphorylation; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger

2014
Induction of Bex genes by curcumin is associated with apoptosis and activation of p53 in N2a neuroblastoma cells.
    Scientific reports, 2017, 02-01, Volume: 7

    Topics: Androstadienes; Animals; Anthracenes; Apoptosis; Benzothiazoles; Cell Line, Tumor; Curcumin; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Neoplastic; JNK Mitogen-Activated Protein Kinases; Mice; Models, Biological; Nerve Tissue Proteins; Neuroblastoma; Phosphatidylinositol 3-Kinases; Phosphorylation; Promoter Regions, Genetic; Signal Transduction; Time Factors; Toluene; Tumor Suppressor Protein p53; Wortmannin

2017
Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 97

    Topics: Anthracenes; Benzhydryl Compounds; Cell Line; Curcumin; Enzyme Activation; Humans; Imidazoles; Inflammation; Insulin Resistance; MAP Kinase Signaling System; NF-kappa B; Oxidative Stress; Phenols; Pyridines; Pyrrolidines; Thiocarbamates

2018
Co-activation of WT1 and AP-1 proteins on WT1 gene promoter to induce WT1 gene expression in K562 cells.
    Cellular signalling, 2019, Volume: 53

    Topics: Abietanes; Anthracenes; Antineoplastic Agents; Curcumin; Gene Expression Regulation, Leukemic; Humans; K562 Cells; Leukemia; Promoter Regions, Genetic; Protein Kinase Inhibitors; Transcription Factor AP-1; WT1 Proteins

2019
Inhibition Of JNK Phosphorylation By Curcumin Analog C66 Protects LPS-Induced Acute Lung Injury.
    Drug design, development and therapy, 2019, Volume: 13

    Topics: Acute Lung Injury; Animals; Anthracenes; Cells, Cultured; Curcumin; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Injections, Intravenous; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Phosphorylation; Structure-Activity Relationship

2019