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pyrazolanthrone and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

pyrazolanthrone has been researched along with 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one in 62 studies

Research

Studies (62)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	30 (48.39)	29.6817
2010's	31 (50.00)	24.3611
2020's	1 (1.61)	2.80

Authors

Authors	Studies
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Alessi, DR; Arthur, JS; Bain, J; Cohen, P; Elliott, M; Hastie, CJ; Klevernic, I; McLauchlan, H; Plater, L; Shpiro, N	1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M	1
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB	1
Augustin, M; Davies, SP; Gao, Y; Harvey, KJ; Kovelman, R; Patel, UA; Woodward, A	1
Caballero, E; García-Cárceles, J; Gil, C; Martínez, A	1
Dobashi, K; Ishizuka, T; Masubuchi, K; Mori, M; Nakazawa, T; Shimizu, Y; Utsugi, M	1
Coppens, A; Hooghe-Peters, E; Kooijman, R	1
Allen, WE; Campbell, M; Sawyer, C; Trimble, ER; Vanhaesebroeck, B	1
Chang, CC; Lee, TS; Shyy, JY; Zhu, Y	1
Chiou, WF; Tsai, HR; Tsai, WJ; Yang, LM	1
Berl, T; Capasso, JM; Rivard, CJ	1
Dent, P; Gao, N; Grant, S; Rahmani, M	1
Chang, SH; Chen, LM; Hsu, HH; Huang, CY; Hwang, JM; Kuo, WW; Lee, SD; Lin, JA; Lu, MC; Wang, CK; Wu, CC	1
Beales, IL; Ogunwobi, O	1
Chayama, K; Kuwahara, K; Miyata, H; Sasaki, T; Serikawa, M	1
Nam, SI	1
Clough, RL; Stefanis, L	1
Han, J; Jeong, YI; Jung, ID; Lee, CM; Lee, JS; Park, WS; Park, YM	1
Carmona-Cuenca, I; Del Castillo, G; Fabregat, I; Fernández, M; Murillo, MM; Ortiz, C; Roncero, C; Sánchez, A	1
Pagliassotti, MJ; Wang, D; Wei, Y	1
Choi, YH; Kim, GY; Lee, KJ; Moon, DO	1
Chen, LN; Fan, CM; Jia, JF; Wang, CH; Wang, YH; Zhu, P	1
Berger, F; Champelovier, P; El Atifi, M; Pautre, V; Rostaing, B; Seigneurin, D	1
Chen, Y; Di, J; Lin, Y; Saito, S; Shen, W; Zeng, S; Zhong, Y	1
Ding, Z; Masamune, A; Maubach, G; Zhuo, L	1
Deng, J; Feng, X; Geng, L; Jiang, G; Liu, J; Qian, Y; Wang, Y; Xie, H; Ye, Z; Yin, S; Zheng, S; Zhou, L	1
Norlin, M; Pettersson, H; Tang, W	1
Hanada, K; Iwasaki, Y; Kageyama, K; Nigawara, T; Sakihara, S; Suda, T; Takayasu, S	1
González, I; Jiménez, E; Montiel, M; Pérez de la Blanca, E; Salas, J; Urso, L	1
Camins, A; Casadesús, G; Folch, J; Pallàs, M; Smith, MA; Yeste-Velasco, M	1
Asano, S; Itoh, M; Nishiwaki-Yasuda, K; Sekiguchi, S; Shibata, M; Suzuki, A	1
Chung, EJ; Jung, SA; Lee, JH; Moon, SW	1
Boulukos, K; Clavel, S; Coldefy, AS; Dérijard, B; Pisani, DF; Siffroi-Fernandez, S	1
Biffo, S; Brina, D; Gandin, V; Marchisio, PC	1
Hosokawa, I; Hosokawa, Y; Matsuo, T; Nakae, H; Ozaki, K; Yumoto, H	1
Dong, J; He, YL; Lei, JX; Liao, EY; Sui, GL; Xiao, LW; Xie, H; Yang, M; Yuan, X	1
Fu, G; Qiu, F; Xu, S; Yu, L; Zhao, Y	1
Doudican, NA; Orlow, SJ; Quay, E; Zhang, S	1
Chang, KC; Jun, MS; Kim, HJ; Kim, HS; Kim, YM; Kim, YS; Lee, JH; Lee, KR; Park, EJ	1
Bai, SZ; Guo, J; He, W; Kong, FJ; Li, GW; Li, HX; Li, HZ; Tian, Y; Wang, R; Wu, LY; Xi, YH; Xing, WJ; Xu, CQ; Yang, GD	1
Bourque, SD; Khatchadourian, A; Maysinger, D; Richard, VR; Titorenko, VI	1
Chen, GJ; Li, XS; Ran, JH; Tan, Y; Tang, WY; Yan, Y; Zhang, XD; Zhong, D	1
Fernández-Galilea, M; Martinez, JA; Moreno-Aliaga, MJ; Pérez-Matute, P; Prieto-Hontoria, PL	2
Bian, XW; Chen, GL; Cui, YH; Duan, JJ; Gu, A; Li, TT; Qian, C; Shi, Y; Xin, YH; Xu, C; Yang, XJ; Yu, SC; Zhang, X	1
Kim, M; Noh, M; Shin, DW; Shin, H; Shin, JH	1
Hwangbo, C; Kim, N; Lee, JH; Lee, S	1
Chen, Z; Gu, X; Lu, L; Qian, S; Wang, L; Wang, Y; Xiang, J	1
Elsum, IA; Humbert, PO; Martin, C	1
Angel, JB; Blahoianu, MA; Kozlowski, M; Kumar, A; Rahimi, AA	1
Alain, LA; Huang, W; Luo, G; Wu, X	1
Chang, HH; Huang, YM; Juan, CC; Kao, CC; Kao, YH; Kuo, YC; Liu, CW; Tang, YC	1
Handa, K; Inukai, K; Ishida, H; Katsuta, H; Kitahara, A; Moriya, R; Nishida, S; Ohno, H; Onuma, H; Sakurai, T; Sumitani, Y; Takahashi, K; Tanaka, T	1
Angel, J; Busca, A; Iqbal, S; Kumar, A; Saxena, M	1
Cai, M; Lou, S; Zhou, B; Zhou, Y	1
Kluftinger, A; Little, JP; Mah, D; Simtchouk, S; Wan, Z	1
Eliopoulos, AG; Sourvinos, G; Vlahava, VM	1
Chou, MY; Hu, FW; Lee, SS; Tsai, CH; Wang, TH; Yang, LC; Yu, CC	1
Choi, S; Jiao, HY; Jun, JY; Kim, MW; Kim, SW; Lee, MJ; Na, J; Park, CG; Park, IK; Shin, DH; So, I	1
Du, D; Li, Y; Liu, Y; Yin, Y; Zong, J	1
Bao, GH; He, BQ; Hu, QM; Liang, JY; Shen, YH; Wang, LY; Wang, P; Wu, FH; Zhang, BB	1

Reviews

1 review(s) available for pyrazolanthrone and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

Article	Year
Kinase Inhibitors as Underexplored Antiviral Agents. Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2 Topics: Animals; Antiviral Agents; Drug Repositioning; Humans; Protein Kinase Inhibitors; Virus Diseases; Viruses	2022

Other Studies

61 other study(ies) available for pyrazolanthrone and 2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one

Article	Year
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
The selectivity of protein kinase inhibitors: a further update. The Biochemical journal, 2007, Dec-15, Volume: 408, Issue:3 Topics: Amino Acid Sequence; Animals; Cell Line; Drug Design; Enzyme Activation; Humans; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; Spodoptera	2007
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51 Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases	2007
Navigating the kinome. Nature chemical biology, 2011, Volume: 7, Issue:4 Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology	2011
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. The Biochemical journal, 2013, Apr-15, Volume: 451, Issue:2 Topics: Aurora Kinases; Cluster Analysis; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; ErbB Receptors; Humans; Intracellular Signaling Peptides and Proteins; MAP Kinase Kinase 4; p38 Mitogen-Activated Protein Kinases; Protein Kinase Inhibitors; Protein Kinases; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Recombinant Proteins; Reproducibility of Results; Signal Transduction; Small Molecule Libraries; Structure-Activity Relationship; Syk Kinase	2013
C-Jun-NH2-terminal kinase mediates expression of connective tissue growth factor induced by transforming growth factor-beta1 in human lung fibroblasts. American journal of respiratory cell and molecular biology, 2003, Volume: 28, Issue:6 Topics: Androstadienes; Anthracenes; Cells, Cultured; Chromones; Connective Tissue Growth Factor; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gene Expression Regulation; Humans; Imidazoles; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; JNK Mitogen-Activated Protein Kinases; Lung; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Morpholines; Oligonucleotides, Antisense; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pyridines; RNA, Messenger; Smad2 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1; Wortmannin	2003
IGF-I stimulates IL-8 production in the promyelocytic cell line HL-60 through activation of extracellular signal-regulated protein kinase. Cellular signalling, 2003, Volume: 15, Issue:12 Topics: Androstadienes; Anthracenes; Apoptosis; Butadienes; Cell Survival; Chromones; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Hydrogen Peroxide; Imidazoles; Insulin-Like Growth Factor I; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Kinetics; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oxazoles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Receptor, IGF Type 1; RNA, Messenger; Wortmannin	2003
Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways. Circulation research, 2004, Aug-20, Volume: 95, Issue:4 Topics: Alkyl and Aryl Transferases; Androstadienes; Anthracenes; Antibodies, Monoclonal; Cells, Cultured; Chemotaxis; Chromones; Class I Phosphatidylinositol 3-Kinases; Farnesyltranstransferase; Flavonoids; Glucose; Humans; Imidazoles; Isoenzymes; JNK Mitogen-Activated Protein Kinases; Lovastatin; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Polyisoprenyl Phosphates; Protein Kinases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; ras Proteins; Sesquiterpenes; Sirolimus; TOR Serine-Threonine Kinases; Wortmannin	2004
Simvastatin induces heme oxygenase-1: a novel mechanism of vessel protection. Circulation, 2004, Sep-07, Volume: 110, Issue:10 Topics: Animals; Anthracenes; Aorta; Cell Division; Cells, Cultured; Chromones; Endothelial Cells; Endothelium, Vascular; Enzyme Activation; Enzyme Induction; Flavonoids; Heme Oxygenase (Decyclizing); Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Macrophages; Mice; Mice, Inbred C57BL; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-kappa B; Nitric Oxide; Organ Specificity; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protoporphyrins; Rats; Rats, Sprague-Dawley; RNA, Small Interfering; Signal Transduction; Simvastatin	2004
Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration. European journal of pharmacology, 2004, Sep-13, Volume: 498, Issue:1-3 Topics: Androstadienes; Animals; Anthracenes; Cell Line; Cell Movement; Cell Survival; Chemokine CCL4; Chemotaxis; Chromones; Complement C5a; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flavonoids; Imidazoles; JNK Mitogen-Activated Protein Kinases; Macrophage Inflammatory Proteins; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Wortmannin	2004
Synthesis of the Na-K-ATPase gamma-subunit is regulated at both the transcriptional and translational levels in IMCD3 cells. American journal of physiology. Renal physiology, 2005, Volume: 288, Issue:1 Topics: Animals; Anthracenes; Cell Line; Chromones; Down-Regulation; Gene Expression Regulation, Enzymologic; JNK Mitogen-Activated Protein Kinases; Kidney Cortex; Kidney Medulla; Kidney Tubules, Collecting; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Protein Biosynthesis; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Transcription, Genetic	2005
2-Methoxyestradiol-induced apoptosis in human leukemia cells proceeds through a reactive oxygen species and Akt-dependent process. Oncogene, 2005, May-26, Volume: 24, Issue:23 Topics: 2-Methoxyestradiol; Anthracenes; Apoptosis; Chromones; Dose-Response Relationship, Drug; Estradiol; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Morpholines; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; U937 Cells; X-Linked Inhibitor of Apoptosis Protein	2005
Porphyromonas gingivalis-related cardiac cell apoptosis was majorly co-activated by p38 and extracellular signal-regulated kinase pathways. Journal of periodontal research, 2006, Volume: 41, Issue:1 Topics: Animals; Anthracenes; Apoptosis; Butadienes; Calcineurin Inhibitors; Caspases; Cell Nucleus; Chromones; Cyclosporine; DNA Fragmentation; Enzyme Inhibitors; Fluorescent Dyes; Imidazoles; Indoles; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Morpholines; Myocardium; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphoinositide-3 Kinase Inhibitors; Porphyromonas gingivalis; Pyridines; Rats	2006
Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways. Molecular and cellular endocrinology, 2006, Mar-09, Volume: 247, Issue:1-2 Topics: Anthracenes; Apoptosis; Celecoxib; Cell Line, Tumor; Cell Survival; Chromones; Colonic Neoplasms; Gastrins; Humans; Janus Kinase 2; JNK Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrazoles; Signal Transduction; STAT3 Transcription Factor; Sulfonamides; Transcription Factor AP-1; Tyrosine; Tyrphostins	2006
The effects of ZD1839 (Iressa), a highly selective EGFR tyrosine kinase inhibitor, as a radiosensitiser in bile duct carcinoma cell lines. International journal of oncology, 2006, Volume: 28, Issue:4 Topics: Anthracenes; Bile Duct Neoplasms; Butadienes; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromones; Clone Cells; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Gefitinib; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Morpholines; Nitriles; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Kinase Inhibitors; Pyridines; Quinazolines; Radiation-Sensitizing Agents	2006
Interleukin-1beta up-regulates inducible nitric oxide by way of phosphoinositide 3-kinase-dependent in a cochlear cell model. The Laryngoscope, 2006, Volume: 116, Issue:12 Topics: Animals; Anthracenes; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Chromones; Enzyme Inhibitors; Flavonoids; Imidazoles; Interleukin-1beta; Mice; Morpholines; Nitric Oxide Synthase Type II; Organ of Corti; Phosphatidylinositol 3-Kinases; Pyridines; Signal Transduction; Transcriptional Activation; Up-Regulation	2006
A novel pathway for transcriptional regulation of alpha-synuclein. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007, Volume: 21, Issue:2 Topics: alpha-Synuclein; Animals; Anthracenes; Blotting, Western; Butadienes; Chromones; Enzyme Inhibitors; Fibroblast Growth Factor 2; Gene Expression Regulation; Humans; Imidazoles; Introns; JNK Mitogen-Activated Protein Kinases; Models, Biological; Morpholines; Nerve Growth Factor; Nitriles; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Rats; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic	2007
Differential regulation of indoleamine 2,3-dioxygenase by lipopolysaccharide and interferon gamma in murine bone marrow derived dendritic cells. FEBS letters, 2007, Apr-03, Volume: 581, Issue:7 Topics: Animals; Anthracenes; Bone Marrow Cells; Butadienes; Chromones; Dendritic Cells; Gene Expression; Gene Expression Regulation, Enzymologic; Imidazoles; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Janus Kinase 1; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Male; Mice; Mice, Inbred Strains; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Pyridines	2007
Activation of NADPH oxidase by transforming growth factor-beta in hepatocytes mediates up-regulation of epidermal growth factor receptor ligands through a nuclear factor-kappaB-dependent mechanism. The Biochemical journal, 2007, Jul-15, Volume: 405, Issue:2 Topics: Acetophenones; Animals; Anthracenes; Benzamides; Chromones; Dioxoles; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Heparin-binding EGF-like Growth Factor; Hepatocytes; Humans; Imidazoles; Intercellular Signaling Peptides and Proteins; Morpholines; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 4; NADPH Oxidases; NF-kappa B; Onium Compounds; Peptides; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Quinazolines; rac1 GTP-Binding Protein; Rats; Reactive Oxygen Species; Transforming Growth Factor beta; Tyrphostins; Up-Regulation	2007
Insulin protects liver cells from saturated fatty acid-induced apoptosis via inhibition of c-Jun NH2 terminal kinase activity. Endocrinology, 2007, Volume: 148, Issue:7 Topics: Androstadienes; Animals; Anthracenes; Apoptosis; Caspase 3; Cell Line, Tumor; Cells, Cultured; Chromones; DNA Fragmentation; Enzyme Activation; Fatty Acids; Female; Hepatocytes; Immunoblotting; Inhibitor of Apoptosis Proteins; Insulin; JNK Mitogen-Activated Protein Kinases; Morpholines; Palmitates; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thapsigargin; Wortmannin	2007
Beta-sitosterol-induced-apoptosis is mediated by the activation of ERK and the downregulation of Akt in MCA-102 murine fibrosarcoma cells. International immunopharmacology, 2007, Volume: 7, Issue:8 Topics: Animals; Anthracenes; Apoptosis; Apoptosis Regulatory Proteins; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Survival; Chromones; Dose-Response Relationship, Drug; Down-Regulation; Extracellular Signal-Regulated MAP Kinases; Fibrosarcoma; G1 Phase; Hypolipidemic Agents; Imidazoles; Mice; Models, Biological; Morpholines; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Pyridines; Signal Transduction; Sitosterols; Tumor Suppressor Protein p53	2007
[CD147 stimulates the angiogenesis in rheumatoid synovium via the activation of vascular endothelial growth factor]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2007, Volume: 23, Issue:5 Topics: Adult; Aged; Anthracenes; Arthritis, Rheumatoid; Basigin; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chromones; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Female; Flavonoids; Humans; Lymphocytes; Macrophages; Male; Middle Aged; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Osteoarthritis; Phosphoinositide-3 Kinase Inhibitors; Polymerase Chain Reaction; Signal Transduction; Synovial Membrane; Vascular Endothelial Growth Factor A; Young Adult	2007
Specific inhibition of basal mitogen-activated protein kinases and phosphatidylinositol 3 kinase activities in leukemia cells: a possible therapeutic role for the kinase inhibitors. Experimental hematology, 2008, Volume: 36, Issue:1 Topics: Anthracenes; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Differentiation; Cell Division; Cell Line, Tumor; Chromones; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Imidazoles; Leukemia; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Monocytes; Morpholines; Neoplasm Proteins; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Pyridines; U937 Cells	2008
Characterization of natural killer cells in nonobese diabetic/severely compromised immunodeficient mice during pregnancy. Fertility and sterility, 2009, Volume: 91, Issue:6 Topics: Animals; Anthracenes; Chromones; Female; Flavonoids; Interleukin-10; Killer Cells, Natural; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Mice, SCID; Morpholines; Placenta; Pregnancy; Pregnancy, Animal; Spleen; Thy-1 Antigens; Toll-Like Receptor 2; Toll-Like Receptor 4	2009
Glial fibrillary acidic protein promoter targets pancreatic stellate cells. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2009, Volume: 41, Issue:3 Topics: Animals; Anthracenes; Butadienes; Cell Line; Chromones; Enzyme Inhibitors; Gene Expression; Glial Fibrillary Acidic Protein; Lac Operon; Mice; Mice, Transgenic; Morpholines; Nitriles; Pancreas; Promoter Regions, Genetic; Transfection; Transforming Growth Factor beta1; Tumor Necrosis Factor-alpha; Vitamin A; Vitamins	2009
TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells. Cancer investigation, 2008, Volume: 26, Issue:8 Topics: Anthracenes; Antigens, CD; B7-H1 Antigen; Carcinoma, Transitional Cell; Cell Line, Tumor; Chromones; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; Imidazoles; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharide Receptors; Lipopolysaccharides; MAP Kinase Signaling System; Morpholines; Neoplasm Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyridines; Toll-Like Receptor 4; Up-Regulation; Urinary Bladder Neoplasms	2008
Involvement of the PI3K/Akt pathway in estrogen-mediated regulation of human CYP7B1: identification of CYP7B1 as a novel target for PI3K/Akt and MAPK signalling. The Journal of steroid biochemistry and molecular biology, 2008, Volume: 112, Issue:1-3 Topics: Anthracenes; Base Sequence; Cell Line, Tumor; Chromones; Cytochrome P450 Family 7; Elafin; Enzyme Activation; Estradiol; Estrogens; Flavonoids; Gene Expression Regulation; Humans; Imidazoles; MAP Kinase Signaling System; Molecular Sequence Data; Morpholines; Promoter Regions, Genetic; Proto-Oncogene Proteins c-akt; Pyridines; Steroid Hydroxylases	2008
Involvement of regulatory elements on corticotropin-releasing factor gene promoter in hypothalamic 4B cells. Journal of endocrinological investigation, 2008, Volume: 31, Issue:12 Topics: Anthracenes; Cell Line; Chromones; Colforsin; Corticotropin-Releasing Hormone; Dexamethasone; Flavonoids; Genes, Reporter; Humans; Hypothalamus; Imidazoles; Isoquinolines; Morpholines; Promoter Regions, Genetic; Protein Kinase Inhibitors; Pyridines; Regulatory Elements, Transcriptional; Sequence Deletion; Sulfonamides; Transfection	2008
Angiotensin II induces MMP 2 activity via FAK/JNK pathway in human endothelial cells. Biochemical and biophysical research communications, 2009, Mar-20, Volume: 380, Issue:4 Topics: Androstadienes; Angiotensin II; Anthracenes; Cells, Cultured; Chromones; Endothelium, Vascular; Enzyme Activation; Focal Adhesion Kinase 1; Humans; JNK Mitogen-Activated Protein Kinases; Matrix Metalloproteinase 2; Morpholines; Oligonucleotides, Antisense; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Umbilical Veins; Wortmannin	2009
Neuroprotection by c-Jun NH2-terminal kinase inhibitor SP600125 against potassium deprivation-induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry. Neuroscience, 2009, Mar-31, Volume: 159, Issue:3 Topics: Animals; Anthracenes; Apoptosis; Cell Cycle; Cells, Cultured; Cerebellum; Chromones; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase 5; Enzyme Inhibitors; Forkhead Transcription Factors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; JNK Mitogen-Activated Protein Kinases; Morpholines; Nerve Tissue Proteins; Neuroprotective Agents; Oxidative Stress; Phosphotransferases; Potassium; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction	2009
Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells. Prostaglandins, leukotrienes, and essential fatty acids, 2009, Volume: 81, Issue:4 Topics: 3T3 Cells; Animals; Anthracenes; Butadienes; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Imidazoles; Mice; Morpholines; Naphthalenes; Nitriles; Osteoblasts; Phosphates; Prostaglandin D2; Pyridines; Signal Transduction; Sirolimus; Sodium	2009
PDGF stimulation of Müller cell proliferation: Contributions of c-JNK and the PI3K/Akt pathway. Biochemical and biophysical research communications, 2009, Oct-09, Volume: 388, Issue:1 Topics: Animals; Anthracenes; Cell Proliferation; Chromones; Enzyme Inhibitors; JNK Mitogen-Activated Protein Kinases; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred BN; Receptors, Platelet-Derived Growth Factor; Retina; Vitreoretinopathy, Proliferative	2009
Regulation of the intracellular localization of Foxo3a by stress-activated protein kinase signaling pathways in skeletal muscle cells. Molecular and cellular biology, 2010, Volume: 30, Issue:2 Topics: Animals; Anthracenes; Cell Line; Cell Nucleus; Chromones; Exportin 1 Protein; Forkhead Box Protein O3; Forkhead Transcription Factors; Humans; Isoquinolines; Karyopherins; MAP Kinase Kinase 3; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; Morpholines; Muscle Cells; Muscle Fibers, Skeletal; Muscle Proteins; Muscular Atrophy; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptors, Cytoplasmic and Nuclear; Signal Transduction; SKP Cullin F-Box Protein Ligases; Sulfonamides; Thiophenes; Transfection	2010
JNK inhibition arrests cotranslational degradation. Biochimica et biophysica acta, 2010, Volume: 1803, Issue:7 Topics: Animals; Anthracenes; Cell Adhesion; Cell Line; Chromones; Cytoskeleton; Enzyme Inhibitors; Fibroblasts; Fibronectins; JNK Mitogen-Activated Protein Kinases; Mice; Morpholines; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases; Protein Biosynthesis	2010
Proinflammatory effects of muramyldipeptide on human gingival fibroblasts. Journal of periodontal research, 2010, Volume: 45, Issue:2 Topics: Acetylmuramyl-Alanyl-Isoglutamine; Adult; Anthracenes; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Chemokine CCL2; Chemokine CXCL10; Chemokine CXCL11; Chromones; Chronic Periodontitis; Enzyme Inhibitors; Female; Fibroblasts; Flavonoids; Gingiva; Humans; Imidazoles; Inflammation Mediators; Interferon-gamma; Interleukin-6; Interleukin-8; JNK Mitogen-Activated Protein Kinases; Male; Middle Aged; Morpholines; Nod2 Signaling Adaptor Protein; Periodontal Attachment Loss; Periodontal Pocket; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Tumor Necrosis Factor-alpha	2010
Stretch-inducible expression of connective tissue growth factor (CTGF) in human osteoblasts-like cells is mediated by PI3K-JNK pathway. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2011, Volume: 28, Issue:2 Topics: Anthracenes; Cell Line; Chromones; Connective Tissue Growth Factor; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Humans; JNK Mitogen-Activated Protein Kinases; Morpholines; Osteoblasts; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Stress, Mechanical	2011
Thymosin β4 activates integrin-linked kinase and decreases endothelial progenitor cells apoptosis under serum deprivation. Journal of cellular physiology, 2011, Volume: 226, Issue:11 Topics: Androstadienes; Annexin A5; Anthracenes; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Proliferation; Cell Survival; Cells, Cultured; Chromones; Culture Media, Serum-Free; Cytochromes c; Endothelial Cells; Enzyme Inhibitors; Humans; Morpholines; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Stem Cells; Thymosin; Wortmannin	2011
Fluvastatin enhances sorafenib cytotoxicity in melanoma cells via modulation of AKT and JNK signaling pathways. Anticancer research, 2011, Volume: 31, Issue:10 Topics: Anthracenes; Benzenesulfonates; Cell Death; Cell Line, Tumor; Cell Proliferation; Chromones; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; Melanoma; Morpholines; Niacinamide; Phenylurea Compounds; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction; Sorafenib	2011
Ethanol extract of Prunella vulgaris var. lilacina inhibits HMGB1 release by induction of heme oxygenase-1 in LPS-activated RAW 264.7 cells and CLP-induced septic mice. Phytotherapy research : PTR, 2012, Volume: 26, Issue:4 Topics: Animals; Anthracenes; Cecum; Cell Line; Cell Survival; Chromones; Cyclooxygenase 2; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Activation; Enzyme Induction; Ethanol; Flavonoids; Flowers; Genetic Vectors; Heme Oxygenase-1; HMGB1 Protein; Imidazoles; Lipopolysaccharides; Lung; Macrophages; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Morpholines; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type II; Plant Extracts; Protein Transport; Prunella; Pyridines; Sepsis; Signal Transduction; Transfection	2012
Involvement of calcium-sensing receptor in oxLDL-induced MMP-2 production in vascular smooth muscle cells via PI3K/Akt pathway. Molecular and cellular biochemistry, 2012, Volume: 362, Issue:1-2 Topics: Adamantane; Animals; Anthracenes; Aorta; Atherosclerosis; Cells, Cultured; Chromones; Gadolinium; JNK Mitogen-Activated Protein Kinases; Lipoproteins, LDL; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Morpholines; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Calcium-Sensing	2012
Dynamics and regulation of lipid droplet formation in lipopolysaccharide (LPS)-stimulated microglia. Biochimica et biophysica acta, 2012, Volume: 1821, Issue:4 Topics: Animals; Anthracenes; Blotting, Western; Cells, Cultured; Chromones; Cytoplasmic Granules; Enzyme Activation; Enzyme Inhibitors; Group IV Phospholipases A2; Imidazoles; JNK Mitogen-Activated Protein Kinases; Kinetics; Lipids; Lipopolysaccharides; Membrane Proteins; Mice; Microglia; Microscopy, Confocal; Models, Biological; Morpholines; Oleic Acid; p38 Mitogen-Activated Protein Kinases; Perilipin-2; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Time Factors; Triglycerides	2012
Mda-9/syntenin promotes human brain glioma migration through focal adhesion kinase (FAK)-JNK and FAK-AKT signaling. Asian Pacific journal of cancer prevention : APJCP, 2012, Volume: 13, Issue:6 Topics: Anthracenes; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Chromones; Focal Adhesion Protein-Tyrosine Kinases; Glioma; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Morpholines; Neoplasm Invasiveness; Phosphorylation; Proto-Oncogene Proteins c-akt; Syntenins	2012
Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes. Journal of lipid research, 2012, Volume: 53, Issue:11 Topics: 3T3-L1 Cells; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anthracenes; Carrier Proteins; Chromones; Isoquinolines; JNK Mitogen-Activated Protein Kinases; Lipase; Lipolysis; Mice; Morpholines; Perilipin-1; Phosphoproteins; Phosphorylation; Quinolones; Ribonucleotides; Sterol Esterase; Sulfonamides; Thioctic Acid	2012
TGF-β1 enhances tumor-induced angiogenesis via JNK pathway and macrophage infiltration in an improved zebrafish embryo/xenograft glioma model. International immunopharmacology, 2013, Volume: 15, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Anthracenes; Cell Line, Tumor; Cell Movement; Chromones; Extracellular Signal-Regulated MAP Kinases; Flavonoids; Glioma; High-Throughput Screening Assays; Humans; Imidazoles; Macrophages; MAP Kinase Kinase 4; Morpholines; Neovascularization, Pathologic; Phosphoinositide-3 Kinase Inhibitors; Pyridines; Signal Transduction; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays; Zebrafish	2013
Tensile stimuli increase nerve growth factor in human dermal fibroblasts independent of tension-induced TGFβ production. Experimental dermatology, 2013, Volume: 22, Issue:1 Topics: Anthracenes; Antibodies, Neutralizing; Butadienes; Chromones; Fibroblasts; Humans; Morpholines; Nerve Growth Factor; Nitriles; RNA, Messenger; Signal Transduction; Skin; Stress, Mechanical; Transcription, Genetic; Transforming Growth Factor beta; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Up-Regulation	2013
Eupatolide inhibits PDGF-induced proliferation and migration of aortic smooth muscle cells through ROS-dependent heme oxygenase-1 induction. Phytotherapy research : PTR, 2013, Volume: 27, Issue:11 Topics: Acetylcysteine; Animals; Anthracenes; Aorta; Butadienes; Cell Movement; Cell Proliferation; Cells, Cultured; Chromones; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Imidazoles; Inula; Male; Morpholines; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NF-E2-Related Factor 2; Nitriles; Platelet-Derived Growth Factor; Pyridines; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Sesquiterpenes	2013
Lipoic acid inhibits adiponectin production in 3T3-L1 adipocytes. Journal of physiology and biochemistry, 2013, Volume: 69, Issue:3 Topics: 3T3-L1 Cells; Adiponectin; Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Animals; Anthracenes; Chromones; Enzyme Inhibitors; Flavonoids; MAP Kinase Kinase 4; Mice; Morpholines; Phosphatidylinositol 3-Kinases; Ribonucleotides; RNA, Messenger; Thioctic Acid	2013
Interferon- γ triggers hepatic stellate cell-mediated immune regulation through MEK/ERK signaling pathway. Clinical & developmental immunology, 2013, Volume: 2013 Topics: Animals; Anthracenes; Antibodies, Neutralizing; Apoptosis; B7-H1 Antigen; Cell Proliferation; Chromones; Gene Expression Regulation; Hepatic Stellate Cells; Immune Tolerance; Interferon-gamma; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Signal Transduction; T-Lymphocytes	2013
Scribble regulates an EMT polarity pathway through modulation of MAPK-ERK signaling to mediate junction formation. Journal of cell science, 2013, Sep-01, Volume: 126, Issue:Pt 17 Topics: Anthracenes; Chromones; Down-Regulation; Epithelial-Mesenchymal Transition; Flavonoids; HEK293 Cells; Homeodomain Proteins; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 1; MAP Kinase Signaling System; Membrane Glycoproteins; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; RNA Interference; RNA, Small Interfering; Tight Junctions; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Tumor Suppressor Proteins; Zinc Finger E-box-Binding Homeobox 1	2013
IFN-γ-induced IL-27 and IL-27p28 expression are differentially regulated through JNK MAPK and PI3K pathways independent of Jak/STAT in human monocytic cells. Immunobiology, 2014, Volume: 219, Issue:1 Topics: Anthracenes; Blotting, Western; Cells, Cultured; Chromones; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Gene Expression; Humans; Interferon-gamma; Interleukin-27; Janus Kinases; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Monocytes; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; STAT Transcription Factors	2014
Hypoxia induces connexin 43 dysregulation by modulating matrix metalloproteinases via MAPK signaling. Molecular and cellular biochemistry, 2013, Volume: 384, Issue:1-2 Topics: Animals; Anthracenes; Butadienes; Cell Hypoxia; Cell Survival; Cells, Cultured; Chromones; Connexin 43; Down-Regulation; Doxycycline; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Morpholines; Myocytes, Cardiac; NF-kappa B; Nitriles; Phenylenediamines; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Rats; Transcription Factor AP-1	2013
Endothelin-1 stimulates resistin gene expression. Endocrinology, 2014, Volume: 155, Issue:3 Topics: 3T3-L1 Cells; Adipose Tissue; Androstadienes; Animals; Anthracenes; Butadienes; Chromones; Dactinomycin; Endothelin-1; Flavonoids; Gene Expression Profiling; Gene Expression Regulation; Male; MAP Kinase Kinase 4; Mice; Mice, Inbred C57BL; Morpholines; Nitriles; Oligopeptides; Piperidines; Proto-Oncogene Proteins c-akt; Resistin; Signal Transduction; STAT3 Transcription Factor; Tyrphostins; Wortmannin	2014
Ghrelin augments the expressions and secretions of proinflammatory adipokines, VEGF120 and MCP-1, in differentiated 3T3-L1 adipocytes. Journal of cellular physiology, 2015, Volume: 230, Issue:1 Topics: 3T3 Cells; Adipocytes; Adiponectin; AMP-Activated Protein Kinases; Androstadienes; Animals; Anthracenes; Cell Line; Chemokine CCL2; Chromones; Diabetes Mellitus, Type 2; Endoplasmic Reticulum Stress; Ghrelin; Interleukin-10; JNK Mitogen-Activated Protein Kinases; Mice; Morpholines; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Proto-Oncogene Proteins c-akt; Vascular Endothelial Growth Factor A; Wortmannin	2015
PI3K/Akt regulates survival during differentiation of human macrophages by maintaining NF-κB-dependent expression of antiapoptotic Bcl-xL. Journal of leukocyte biology, 2014, Volume: 96, Issue:6 Topics: Anthracenes; Apoptosis; bcl-X Protein; Caffeic Acids; Cell Line, Tumor; Chromones; Flavonoids; Gene Expression Regulation, Developmental; Hematopoiesis; Humans; Macrophage Colony-Stimulating Factor; Macrophages; MAP Kinase Signaling System; Monocytes; Morpholines; NF-kappa B; Phenylethyl Alcohol; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Sesquiterpenes; Signal Transduction; Tetradecanoylphorbol Acetate	2014
Hypoxic conditioned medium from rat cerebral cortical cells enhances the proliferation and differentiation of neural stem cells mainly through PI3-K/Akt pathways. PloS one, 2014, Volume: 9, Issue:11 Topics: Animals; Anthracenes; Brain-Derived Neurotrophic Factor; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cerebral Cortex; Chromones; Culture Media, Conditioned; Hypoxia; Morpholines; Neural Stem Cells; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Vascular Endothelial Growth Factor A	2014
Human adipose tissue conditioned media from lean subjects is protective against H2O2 induced neurotoxicity in human SH-SY5Y neuronal cells. International journal of molecular sciences, 2015, Jan-06, Volume: 16, Issue:1 Topics: Adipose Tissue; Alzheimer Disease; Anthracenes; Cell Line, Tumor; Cell Survival; Chromones; Culture Media, Conditioned; Flavonoids; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction	2015
CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism. Cellular signalling, 2015, Volume: 27, Issue:6 Topics: Anthracenes; Antiviral Agents; Autophagy; Autophagy-Related Protein 5; Benzylamines; CD40 Ligand; Cell Line, Tumor; Cell Nucleus; Chromones; Herpes Simplex Virus Protein Vmw65; Herpesvirus 1, Human; Humans; JNK Mitogen-Activated Protein Kinases; Macrolides; Microtubule-Associated Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinazolines; RNA Interference; RNA, Small Interfering; Signal Transduction; Virus Replication	2015
Knockdown of S100A4 impairs arecoline-induced invasiveness of oral squamous cell carcinomas. Oral oncology, 2015, Volume: 51, Issue:7 Topics: Anthracenes; Areca; Carcinoma, Squamous Cell; Chromones; Enzyme Inhibitors; Female; Humans; Lymphatic Metastasis; Male; Mastication; Morpholines; Mouth Mucosa; Mouth Neoplasms; Neoplasm Invasiveness; S100 Calcium-Binding Protein A4; S100 Proteins; Survival Rate	2015
Regulatory Roles of Endogenous Mitogen-Activated Protein Kinases and Tyrosine Kinases in the Pacemaker Activity of Colonic Interstitial Cells of Cajal. Pharmacology, 2015, Volume: 96, Issue:1-2 Topics: Animals; Anthracenes; Benzophenanthridines; Cells, Cultured; Chromones; Colon; Flavonoids; Genistein; Imidazoles; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mitogen-Activated Protein Kinases; Morpholines; Naphthalenes; Protein-Tyrosine Kinases; Pyridines; Rifabutin	2015
CD147 induces up-regulation of vascular endothelial growth factor in U937-derived foam cells through PI3K/AKT pathway. Archives of biochemistry and biophysics, 2016, Nov-01, Volume: 609 Topics: Anthracenes; Atherosclerosis; Basigin; Butadienes; Chromones; Flow Cytometry; Foam Cells; Gene Expression Regulation; Gene Silencing; Humans; Imidazoles; Lipoproteins, LDL; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction; U937 Cells; Up-Regulation; Vascular Endothelial Growth Factor A	2016
Ethyl Rosmarinate Protects High Glucose-Induced Injury in Human Endothelial Cells. Molecules (Basel, Switzerland), 2018, Dec-19, Volume: 23, Issue:12 Topics: Anthracenes; Apoptosis; Cell Survival; Cells, Cultured; Chromones; Cinnamates; Depsides; Endothelial Cells; Glucose; Humans; Molecular Docking Simulation; Morpholines; NF-kappa B; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Rosmarinic Acid; Signal Transduction	2018