pyrazofurin has been researched along with 3-deazaguanine* in 2 studies
2 other study(ies) available for pyrazofurin and 3-deazaguanine
| Article | Year |
|---|---|
Use of lactate dehydrogenase to evaluate the anti-viral activity against influenza A virus.
The detection of lactate dehydrogenase (LDH) can be used to evaluate efficiently anti-influenza A virus agents. LDH levels in the virus-infected Madin-Darby canine kidney cell cultures were significantly higher than in controls, were in proportion to the degree of virus infection, and corresponded to a decrease in mitochondrial dehydrogenase activity as assayed using a tetrazolium colorimetric assay (MTT method). The EC50 value and cytotoxicity of ribavirin, 3-deazaguanine, pyrazofurin, and carbodine against influenza A virus as measured by the LDH detection method was equivalent to that derived by the MTT method. Topics: Amides; Animals; Antiviral Agents; Cell Line; Colorimetry; Coloring Agents; Cytidine; Dogs; Guanine; Influenza A virus; L-Lactate Dehydrogenase; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Tetrazolium Salts; Thiazoles | 1995 |
Inhibitory effects of several antiviral compounds on the replication of respiratory syncytial virus in vitro.
Topics: Amides; Antiviral Agents; Cytidine; Dose-Response Relationship, Drug; Guanine; HeLa Cells; Humans; Pyrazoles; Respiratory Syncytial Viruses; Ribavirin; Ribonucleosides; Ribose; Tubercidin; Virus Replication | 1985 |