pyrazinoic acid has been researched along with niacin in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Averbuj, C; Boatman, PD; Chen, R; Cherrier, MC; Colletti, SL; Connolly, DT; Decaire, M; Duong, T; Gharbaoui, T; Johnson, BR; Jung, JK; Lindstrom, A; Richman, JG; Rodriguez, N; Sage, CR; Schrader, TO; Semple, G; Shin, YJ; Skinner, PJ; Smith, BM; Tamura, SY; Tata, JR; Uy, J; Webb, PJ; Xu, J; Zou, N | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Bao, R; He, L; Ju, Y; Li, C; Luo, Y; Sang, Z; Song, R; Sun, K; Yang, T; Yang, Y; Zhou, Y | 1 |
| Aldrich, CC; Aragaw, WW; Cole, MS; Dick, T; Grüber, G; Harikishore, A; Hegde, PV; Jachak, G; Ragunathan, P; Sharma, S | 1 |
| Aronson, PS; Guggino, SE | 1 |
| Cynamon, MH; Speirs, RJ; Welch, JT | 1 |
| Heinzmann, K; Kiener, A; Tinschert, A; Tschech, A | 1 |
| Fukuwatari, T; Shibata, K; Sugimoto, E | 1 |
| FERRARI, S; MORELLINI, M | 1 |
| AOKI, T; ITO, F; NISHIO, K | 1 |
| BERGER, L; GUTMAN, AB; STONE, DJ; WOLF, J; YU, TF | 1 |
| BUGIE, EJ; GREGORY, FJ; IRONSON, EJ; O'NEILL, RC; PFISTER, R; SOLOTOROVSKY, M | 1 |
| Akashi, I; Hirano, T; Kagami, K; Oka, K | 1 |
| Anzai, N; Nakanishi, T; Ohya, K; Shimada, S; Tamai, I | 1 |
14 other study(ies) available for pyrazinoic acid and niacin
| Article | Year |
|---|---|
Agonist lead identification for the high affinity niacin receptor GPR109a.
Topics: Acids, Heterocyclic; Adipocytes; Animals; Chemistry, Pharmaceutical; Cyclic AMP; Drug Design; Humans; Kinetics; Models, Chemical; Niacin; Pyrazoles; Rats; Receptors, G-Protein-Coupled; Receptors, Nicotinic; Spleen | 2007 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Discovery of Novel Peptidomimetic Boronate ClpP Inhibitors with Noncanonical Enzyme Mechanism as Potent Virulence Blockers
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Boron Compounds; Boronic Acids; Endopeptidase Clp; Female; Glycine; Humans; Methicillin-Resistant Staphylococcus aureus; Mice, Inbred BALB C; Molecular Docking Simulation; Molecular Structure; Peptidomimetics; Protein Binding; Serine Proteinase Inhibitors; Skin; Small Molecule Libraries; Staphylococcal Skin Infections; Structure-Activity Relationship; Virulence | 2020 |
Structure activity relationship of pyrazinoic acid analogs as potential antimycobacterial agents.
Topics: Amidohydrolases; Antitubercular Agents; Carboxylic Acids; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Mutation; Mycobacterium tuberculosis; Pyrazinamide; Structure-Activity Relationship; Tuberculosis | 2022 |
Paradoxical effects of pyrazinoate and nicotinate on urate transport in dog renal microvillus membranes.
Topics: Animals; Biological Transport, Active; Dogs; Hydrogen-Ion Concentration; Kidney Cortex; Lactates; Lactic Acid; Membranes; Microvilli; Models, Biological; Niacin; Nigericin; Pyrazinamide; Sodium; Uric Acid; Valinomycin | 1985 |
Activity of n-propyl pyrazinoate against pyrazinamide-resistant Mycobacterium tuberculosis: investigations into mechanism of action of and mechanism of resistance to pyrazinamide.
Topics: Amidohydrolases; Antibiotics, Antitubercular; Drug Resistance, Microbial; Esterases; Microbial Sensitivity Tests; Mycobacterium; Mycobacterium tuberculosis; Niacin; Pyrazinamide; Structure-Activity Relationship | 1995 |
Novel regioselective hydroxylations of pyridine carboxylic acids at position C2 and pyrazine carboxylic acids at position C3.
Topics: Biotransformation; Carboxylic Acids; Culture Media; Gram-Negative Aerobic Rods and Cocci; Hydroxylation; Niacin; Nicotinic Acids; Pyrazinamide; Pyridines; Spectrophotometry, Ultraviolet; Time Factors | 2000 |
Growth-promoting activity of pyrazinoic acid, a putative active compound of antituberculosis drug pyrazinamide, in niacin-deficient rats through the inhibition of ACMSD activity.
Topics: Animals; Antitubercular Agents; Carboxy-Lyases; Diet; Eating; Injections, Intraperitoneal; Kidney; Kynurenic Acid; Liver; Male; NAD; Niacin; Pyrazinamide; Rats; Rats, Wistar; Tryptophan; Weight Gain; Xanthurenates | 2002 |
[Activity of pyrazinamide (pyrazine-2-carboxylic acid amide) in experimental tuberculosis of the cavy].
Topics: Amides; Guinea Pigs; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis | 1956 |
[Research on the metabolic fate of pyrazinamide; pyrazinoic acid formation by liver homogenates in vitro].
Topics: In Vitro Techniques; Liver; Niacin; Nicotinic Acids; Pyrazinamide; Research | 1957 |
Effect of pyrazinamide and pyrazinoic acid on urate clearance and other discrete renal functions.
Topics: Humans; Kidney Function Tests; Niacin; Nicotinic Acids; Pyrazinamide; Uric Acid; Urinary Tract Physiological Phenomena | 1957 |
Pyrazinoic acid amide; an agent active against experimental murine tuberculosis.
Topics: Amides; Animals; Humans; Mice; Niacin; Nicotinic Acids; Pyrazinamide; Tuberculosis | 1952 |
Protective effects of coffee-derived compounds on lipopolysaccharide/D-galactosamine induced acute liver injury in rats.
Topics: Alanine Transaminase; Alkaloids; Animals; Aspartate Aminotransferases; Caffeine; Chemical and Drug Induced Liver Injury; Chlorogenic Acid; Coffee; Galactosamine; Interleukin-10; Lipopolysaccharides; Liver Diseases; Male; Niacin; Pyrazinamide; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha | 2009 |
Functional cooperation of URAT1 (SLC22A12) and URATv1 (SLC2A9) in renal reabsorption of urate.
Topics: Animals; Benzbromarone; Cells, Cultured; Dogs; Fluorescent Antibody Technique; Glucose Transport Proteins, Facilitative; Humans; Kidney; Lactic Acid; Madin Darby Canine Kidney Cells; Niacin; Oocytes; Organic Anion Transporters; Organic Cation Transport Proteins; Pyrazinamide; Uric Acid; Uricosuric Agents; Vasodilator Agents; Xenopus laevis | 2013 |