pyrazines has been researched along with warfarin in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Legrum, W; Meyer, S | 1 |
| Hsu, PL; Luzzi, LA; Ma, JK | 1 |
| Huang, JC; Sun, AX; Wang, RX; Wang, XR | 1 |
| Davis, MC; Franzblau, SG; Martin, AR; Wächter, GA | 1 |
| Nicholson, NS; Parlow, JJ; Salyers, AK; South, MS; Suleymanov, OD; Szalony, JA; Wood, RS | 1 |
| Hintz, KK; Ren, J | 1 |
| Anselmino, A; Atzori, C; Cargnel, A; Mazza, F; Piccinini, M; Rinaudo, MT; Tronconi, E; Valerio, A | 1 |
| Dolcet, X; Encinas, M; Eritja, N; Llobet, D; Llombart-Cussac, A; Marti, RM; Matias-Guiu, X; Schoenenberger, JA; Sorolla, A; Yeramian, A | 1 |
| Casadonte, F; Focà, D; Macrina, L; Malara, N; Santoro, L; Savino, R; Scaramuzzino, M; Sesto, MF; Terracciano, R | 1 |
| Childers, A; Itoh, K; Kleiner, HE; Li, Y; Prince, M; Yamamoto, M | 1 |
| Herman, GA; Johnson-Levonas, AO; Liu, Q; Maes, A; Wagner, JA; Wright, DH | 1 |
| Andreeff, M; Asou, H; Inaba, T; Jin, L; Kimura, S; Konopleva, M; Kuroda, J; Miida, T; Tabe, Y; Zhou, Y | 1 |
| Brioli, A; Cavo, M; Pantani, L; Tacchetti, P; Zamagni, E; Zannetti, B | 1 |
| Bruderer, S; Dingemanse, J; Mant, T; Mukai, H; Okubo, K | 1 |
| Ambrose, AJ; Axelrod, J; Beuzer, P; Cang, H; Chapman, E; Costa-Lotufo, LV; Fuchs, PL; Jimenez, PC; Kumar Kanduluru, A; La Clair, JJ; Rocha, DD; Santos, EA; Wilke, DV | 1 |
| Chen, KY; Fagin, JA; Ghossein, R; Knauf, JA; Luckett, KA; Socci, ND; Voza, F | 1 |
| Dai, X; Liao, Y; Sheng, M; Shi, X; Wu, X | 1 |
| Chiba, N; Hata, M; Hidaka, S; Imai, T; Kikuchi, N; Sakurai, A; Sekimoto, M | 1 |
2 trial(s) available for pyrazines and warfarin
| Article | Year |
|---|---|
Multiple doses of sitagliptin, a selective DPP-4 inhibitor, do not meaningfully alter pharmacokinetics and pharmacodynamics of warfarin.
Topics: Adolescent; Adult; Anticoagulants; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Drug Administration Schedule; Drug Interactions; Female; Humans; International Normalized Ratio; Male; Middle Aged; Prothrombin Time; Pyrazines; Sitagliptin Phosphate; Triazoles; Warfarin | 2009 |
Investigation of Potential Pharmacodynamic and Pharmacokinetic Interactions Between Selexipag and Warfarin in Healthy Male Subjects.
Topics: Acetamides; Acetates; Adolescent; Adult; Anticoagulants; Cross-Over Studies; Double-Blind Method; Drug Interactions; Humans; International Normalized Ratio; Male; Middle Aged; Pyrazines; Warfarin; Young Adult | 2016 |
16 other study(ies) available for pyrazines and warfarin
| Article | Year |
|---|---|
The combinations of inducers of the coumarin hydroxylase-locus help investigate their mode of action.
Topics: Amitrole; Animals; Aryl Hydrocarbon Hydroxylases; Coumarins; Cytochrome P-450 CYP2A6; Enzyme Induction; Liver; Male; Mice; Mice, Inbred DBA; Mixed Function Oxygenases; Phenobarbital; Pyrazines; Pyrazoles | 1989 |
Interactions of sulfonylureas with plasma proteins.
Topics: Acetohexamide; Acridines; Aniline Compounds; Animals; Binding Sites; Blood Proteins; Cattle; Chlorpropamide; Cyclohexanes; Glyburide; Humans; Hypoglycemic Agents; Naphthalenesulfonates; Protein Binding; Pyrazines; Serum Albumin; Serum Albumin, Bovine; Spectrometry, Fluorescence; Sulfonylurea Compounds; Tolbutamide; Warfarin | 1974 |
[Effects of scoparone on hemodynamics in anesthetized rabbits].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cerebrovascular Circulation; Coumarins; Dose-Response Relationship, Drug; Male; Papaverine; Pyrazines; Rabbits; Vasodilator Agents | 1993 |
Antimycobacterial activity of substituted isosteres of pyridine- and pyrazinecarboxylic acids.
Topics: Antitubercular Agents; Coumarins; Esters; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazines; Pyridines; Structure-Activity Relationship | 1998 |
Assessment of bleeding propensity in non-human primates by combination of selective tissue factor/VIIa inhibition and aspirin compared to warfarin and aspirin treatment.
Topics: Aminobenzoates; Animals; Anticoagulants; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Drug Combinations; Factor VIIa; Hemorrhage; Macaca fascicularis; Male; Platelet Aggregation Inhibitors; Prothrombin Time; Pyrazines; Thromboplastin; Warfarin; Whole Blood Coagulation Time | 2004 |
Tetramethylpyrazine elicits disparate responses in cardiac contraction and intracellular Ca(2+) transients in isolated adult rat ventricular myocytes.
Topics: Amidines; Animals; Calcium Signaling; Coumarins; Enzyme Inhibitors; Fluorescent Dyes; Fura-2; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Myocytes, Cardiac; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyrazines; Rats; Vasodilator Agents | 2003 |
Detection of a proteasome in Pneumocystis carinii and its modulation by specific proteasome inhibitors.
Topics: Acetylcysteine; Animals; Boronic Acids; Bortezomib; Cell Line; Coumarins; Genes, Fungal; HIV Protease Inhibitors; Humans; Lopinavir; Models, Animal; Oligopeptides; Pneumocystis carinii; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrimidinones; Rats | 2006 |
Antioxidants block proteasome inhibitor function in endometrial carcinoma cells.
Topics: Antioxidants; Antipyrine; Apoptosis; Ascorbic Acid; Blotting, Western; Boronic Acids; Bortezomib; Butylated Hydroxyanisole; Caspase 3; Caspase 9; Caspase Inhibitors; Cell Line, Tumor; Cell Survival; Coumarins; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Edaravone; Endometrial Neoplasms; Ergothioneine; Female; Humans; Leupeptins; Oligopeptides; Proteasome Inhibitors; Pyrazines; Ubiquitin; Vitamin E; Vitamins | 2008 |
Simultaneous inhibition of the constitutively activated nuclear factor kappaB and of the interleukin-6 pathways is necessary and sufficient to completely overcome apoptosis resistance of human U266 myeloma cells.
Topics: Adenoviridae; Animals; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Coumarins; Ergosterol; Genetic Vectors; Humans; Interleukin-6; Multiple Myeloma; NF-kappa B; Protease Inhibitors; Pyrazines; S Phase; Signal Transduction; STAT3 Transcription Factor; Withanolides | 2008 |
Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Basic-Leucine Zipper Transcription Factors; Cell Line, Tumor; Citrus; Coumarins; Cytosol; Female; Glutathione Transferase; Green Fluorescent Proteins; Humans; Liver; Male; Mice; Mice, Knockout; NAD(P)H Dehydrogenase (Quinone); NADPH Dehydrogenase; Pyrazines; Response Elements; Thiones; Thiophenes; Transfection | 2009 |
Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma.
Topics: Antineoplastic Agents; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; Blotting, Western; Boronic Acids; Bortezomib; Cell Cycle; Cell Proliferation; Coumarins; Cyclin D1; Drug Synergism; Drug Therapy, Combination; Flow Cytometry; HSP90 Heat-Shock Proteins; Humans; Immunoenzyme Techniques; Immunoprecipitation; Lymphoma, Mantle-Cell; Mutation; Oncogene Protein v-akt; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-raf; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2011 |
Multiple myeloma, venous thromboembolism, and treatment-related risk of thrombosis.
Topics: Activated Protein C Resistance; Aged; Anticoagulants; Aspirin; Boronic Acids; Bortezomib; Dexamethasone; Humans; Immunologic Factors; International Normalized Ratio; Lenalidomide; Multiple Myeloma; Proteasome Inhibitors; Pyrazines; Risk Factors; Thalidomide; Thrombosis; Venous Thromboembolism; Warfarin | 2011 |
Ritterostatin G
Topics: Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Coumarins; Drug Delivery Systems; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Molecular Probes; Molecular Structure; Phenazines; Protein Binding; Pyrazines; Steroids | 2017 |
Hgf/Met activation mediates resistance to BRAF inhibition in murine anaplastic thyroid cancers.
Topics: Amino Acid Substitution; Animals; Antineoplastic Agents; Cell Line, Tumor; Coumarins; Crizotinib; Disease Models, Animal; Drug Resistance, Neoplasm; Genes, p53; Humans; Indoles; MAP Kinase Signaling System; Mice; Mice, Transgenic; Mutation, Missense; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-met; Pyrazines; Sulfonamides; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Triazoles | 2018 |
Investigation on drug entrapment location in liposomes and transfersomes based on molecular dynamics simulation.
Topics: Coumarins; Drug Carriers; Fluorouracil; Liposomes; Molecular Dynamics Simulation; Pyrazines; Solubility | 2021 |
Elevated INR in a COVID-19 patient after concomitant administration of favipiravir and warfarin: A case report.
Topics: Amides; Anticoagulants; COVID-19 Drug Treatment; Drug Interactions; Humans; International Normalized Ratio; Pyrazines; Warfarin | 2022 |