pyrazines has been researched along with uk 66914 in 9 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gwilt, M; Henderson, CG; Orme, J; Rourke, JD | 2 |
| Blackburn, KJ; Burges, RA; Cross, PE; Dalrymple, HW; Dickinson, RP; Gwilt, M; Higgins, AJ | 1 |
| Baskin, EP; Brookes, LM; Claremon, DA; Lynch, JJ; Selnick, HG; Serik, CM; Wallace, AA | 1 |
| Brookes, LM; Claremon, DA; Lynch, JJ; Selnick, HG; Stupienski, RF; Wallace, AA | 1 |
| MacKenzie, I; Saville, VL; Waterfall, JF | 1 |
| Henderson, C; Kane, K; Tweedie, D | 1 |
| Curtis, MJ; Rees, SA | 1 |
| Powell, T; Rees, SA; Vandenberg, JI; Wright, AR; Yoshida, A | 1 |
9 other study(ies) available for pyrazines and uk 66914
| Article | Year |
|---|---|
Effects of drugs on ventricular fibrillation and ischaemic K+ loss in a model of ischaemia in perfused guinea-pig hearts in vitro.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Benzothiazoles; Calcium Channel Blockers; Disease Models, Animal; Glipizide; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Myocardial Ischemia; Piperidines; Potassium; Potassium Channels; Pyrazines; Pyridines; Sympatholytics; Thiazoles; Ventricular Fibrillation | 1992 |
Electrophysiologic properties of UK-66,914, a novel class III antiarrhythmic agent.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Dogs; Dose-Response Relationship, Drug; Heart; Heart Conduction System; In Vitro Techniques; Male; Purkinje Fibers; Pyrazines; Pyridines; Refractory Period, Electrophysiological | 1991 |
Effects of new and potent methanesulfonanilide class III antiarrhythmic agents on myocardial refractoriness and contractility in isolated cardiac muscle.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Ferrets; Heart; Hypoxia; In Vitro Techniques; Male; Myocardial Contraction; Phenethylamines; Piperidines; Pyrazines; Pyridines; Refractory Period, Electrophysiological; Sotalol; Sulfonamides; Temperature | 1991 |
Cardiac electrophysiologic and inotropic actions of new and potent methanesulfonanilide class III antiarrhythmic agents in anesthetized dogs.
Topics: Animals; Anti-Arrhythmia Agents; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Electrophysiology; Female; Heart; Hemodynamics; Male; Myocardial Contraction; Phenethylamines; Piperidines; Pyrazines; Pyridines; Refractory Period, Electrophysiological; Sotalol; Sulfonamides | 1991 |
K(+)-channel blockers and coronary vasoconstriction in guinea-pig perfused hearts in-vitro.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Coronary Vessels; Glipizide; Glyburide; Guinea Pigs; In Vitro Techniques; Male; Perfusion; Phentolamine; Potassium Channels; Pyrazines; Pyridines; Vasoconstriction | 1993 |
Differential class III and glibenclamide effects on action potential duration in guinea-pig papillary muscle during normoxia and hypoxia/ischaemia.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Electrophysiology; Glyburide; Guinea Pigs; Heart; Hypoxia; In Vitro Techniques; Microelectrodes; Myocardial Ischemia; Papillary Muscles; Piperidines; Potassium Channels; Pyrazines; Pyridines; Sotalol | 1993 |
Glibenclamide, but not class III drugs, prevents ischaemic shortening of the refractory period in guinea-pig hearts.
Topics: Analysis of Variance; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Electrocardiography; Glyburide; Guinea Pigs; Heart; Male; Myocardial Ischemia; Phenethylamines; Phentolamine; Pyrazines; Pyridines; Refractory Period, Electrophysiological; Sulfonamides; Temperature | 1993 |
Selective IK blockade as an antiarrhythmic mechanism: effects of UK66,914 on ischaemia and reperfusion arrhythmias in rat and rabbit hearts.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Heart; Hemodynamics; In Vitro Techniques; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Potassium; Pyrazines; Pyridines; Rabbits; Rats; Rats, Wistar; Ventricular Fibrillation | 1993 |
Cell swelling has differential effects on the rapid and slow components of delayed rectifier potassium current in guinea pig cardiac myocytes.
Topics: Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Kinetics; Membrane Potentials; Nifedipine; Phenethylamines; Potassium Channels; Pyrazines; Pyridines; Sulfonamides | 1995 |