pyrazines has been researched along with u 0126 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Edvinsson, L; Maddahi, A | 1 |
| Chen, X; Liu, Y; Shi, Q; Tian, Y; Yang, P; Zhang, H; Zhang, J | 1 |
| Eckhardt, SG; Flanigan, SA; Kachaeva, MI; Kulikowski, GN; Leong, S; McManus, MC; Newton, TP; Pitts, TM; Selby, HM; Spreafico, A; Tan, AC; Tentler, JJ | 1 |
| Amin, HM; Chen, Z; He, Y; Shen, C; Song, YH; Wang, Y; Wu, D; Xing, S; Yang, S; Yue, Y | 1 |
| Barreiro, E; Chacon-Cabrera, A; de Kier Joffé, ED; Diament, MJ; Fermoselle, C; Mateu-Jimenez, M; Sandri, M; Urtreger, AJ | 1 |
| Bogachkov, Y; Doscas, ME; Kaufman, H; Li, Y; Rao, GS; Ruby, C; Usha, L; Wang, Y; Williams, JW; Williamson, AJ; Xiao, F; Xu, X; Zhou, J | 1 |
| Bonetti, B; Cavenee, WK; Chopra, R; Cloughesy, TF; Ding, X; Gini, B; Gu, Y; Heath, JR; Herrmann, K; Hwang, K; Ikegami, S; James, CD; Johnson, D; Kim, J; Li, X; Masui, K; Matsutani, T; Mischel, PS; Shin, YS; Su, Y; Wei, W; Xue, M; Yang, H; Zhou, J | 1 |
7 other study(ies) available for pyrazines and u 0126
| Article | Year |
|---|---|
Cerebral ischemia induces microvascular pro-inflammatory cytokine expression via the MEK/ERK pathway.
Topics: Animals; Brain; Butadienes; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Infarction, Middle Cerebral Artery; Male; MAP Kinase Kinase Kinases; Neurologic Examination; Nitric Oxide Synthase Type II; Nitriles; Pyrazines; Rats; Rats, Wistar; Signal Transduction; Sulfonamides; Time Factors | 2010 |
Tetramethylpyrazine promotes proliferation and differentiation of neural stem cells from rat brain in hypoxic condition via mitogen-activated protein kinases pathway in vitro.
Topics: Animals; Butadienes; Cell Differentiation; Cell Hypoxia; Cell Proliferation; Cerebral Cortex; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neurons; Neuroprotective Agents; Nitriles; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyrazines; Rats; Rats, Sprague-Dawley; Stem Cells | 2010 |
Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzimidazoles; Butadienes; Caspase 3; Caspase 7; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Humans; Imidazoles; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mice; Mice, Nude; Neoplasm Transplantation; Nitriles; Protein Kinase Inhibitors; Pyrazines; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction; Transplantation, Heterologous | 2013 |
Reversal of bortezomib resistance in myelodysplastic syndrome cells by MAPK inhibitors.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Bone Marrow Cells; Boronic Acids; Bortezomib; Butadienes; Cell Cycle Proteins; Cell Line, Tumor; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; Flavonoids; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Nitriles; Nuclear Proteins; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazines | 2014 |
Pharmacological strategies in lung cancer-induced cachexia: effects on muscle proteolysis, autophagy, structure, and weakness.
Topics: Animals; Autophagy; Boronic Acids; Bortezomib; Butadienes; Cachexia; Cell Line, Tumor; Inflammation; Lung Neoplasms; Mice; Mice, Inbred BALB C; Muscle Contraction; Muscle Proteins; Muscle Weakness; Muscle, Skeletal; NF-kappa B; Nitriles; Oxidation-Reduction; Proteolysis; Pyrazines; Signal Transduction; Sulfasalazine; Tyrosine; Weight Gain | 2014 |
Inhibition of p70 S6 kinase (S6K1) activity by A77 1726 and its effect on cell proliferation and cell cycle progress.
Topics: Aniline Compounds; Butadienes; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Chromones; Crotonates; Feedback, Physiological; Gene Knockdown Techniques; Humans; Hydroxybutyrates; Imidazoles; Isoxazoles; Leflunomide; MAP Kinase Signaling System; Morpholines; Nitriles; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Pyrazines; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases, 70-kDa; Toluidines | 2014 |
Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma.
Topics: Adaptation, Physiological; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Butadienes; Dasatinib; Drug Resistance, Neoplasm; Drug Synergism; ErbB Receptors; Gene Expression Profiling; Genes, erbB-1; Glioblastoma; Humans; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Mice; Models, Biological; Molecular Targeted Therapy; Multiprotein Complexes; Mutation; Neoplasm Proteins; Nitriles; Phosphoproteins; Protein Kinase Inhibitors; Proteomics; Pyrazines; Selection, Genetic; Signal Transduction; Single-Cell Analysis; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2016 |