Page last updated: 2024-08-21

pyrazines and thromboplastin

pyrazines has been researched along with thromboplastin in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
LaChance, RM; Nicholson, NS; Parlow, JJ; Salyers, AK; South, MS; Suleymanov, OD; Szalony, JA; Wood, RS1
Case, BL; Clare, M; Dice, TA; Fenton, RL; Girard, TJ; Hayes, MJ; Jones, DE; Kurumbail, RG; Lachance, RM; Neumann, WL; Nicholson, NS; Parlow, JJ; South, MS; Stallings, WC; Stegeman, RA; Stevens, AM; Wood, RS1
Nicholson, NS; Parlow, JJ; Salyers, AK; South, MS; Suleymanov, OD; Szalony, JA; Wood, RS1
Cheng, CY; He, SL; He, XF; Jiang, HH; Lin, GQ; Sun, Y; Tian, XM; Wang, GF; Wen, ZB1
Auwerda, JJ; Bertina, RM; de Maat, MP; Leebeek, FW; Osanto, S; Sonneveld, P; Yuana, Y1
Chen, Z; Huo, JR; Yang, L; Zhu, HY1
Chen, XY; Jin, J; Li, WP; Rao, SM; Yan, FZ; Yan, JS; Yang, Y; Zhao, J1
Arai, R; Fujimoto, K; Isozumi, Y; Koyama, T1

Trials

1 trial(s) available for pyrazines and thromboplastin

ArticleYear
Microparticle-associated tissue factor activity and venous thrombosis in multiple myeloma.
    Thrombosis and haemostasis, 2011, Volume: 105, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Case-Control Studies; Cell-Derived Microparticles; Dexamethasone; Doxorubicin; Female; Humans; Male; Middle Aged; Multiple Myeloma; Pyrazines; Thalidomide; Thromboplastin; Venous Thrombosis; Vincristine

2011

Other Studies

7 other study(ies) available for pyrazines and thromboplastin

ArticleYear
Pharmacological interruption of acute thrombus formation with minimal hemorrhagic complications by a small molecule tissue factor/factor VIIa inhibitor: comparison to factor Xa and thrombin inhibition in a nonhuman primate thrombosis model.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:3

    Topics: Aminobenzoates; Animals; Bleeding Time; Dose-Response Relationship, Drug; Factor VIIa; Factor Xa Inhibitors; Fibrinolytic Agents; Forearm; Hemodynamics; Macaca fascicularis; Male; Prothrombin Time; Pyrazines; Sodium Chloride; Thrombin; Thromboplastin; Thrombosis

2003
Design, parallel synthesis, and crystal structures of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.
    Journal of medicinal chemistry, 2003, Sep-11, Volume: 46, Issue:19

    Topics: Antithrombin III; Binding Sites; Combinatorial Chemistry Techniques; Crystallography, X-Ray; Drug Design; Factor VIIa; Fibrinolytic Agents; Humans; Inhibitory Concentration 50; Models, Molecular; Pyrazines; Recombinant Proteins; Serine Proteinase Inhibitors; Structure-Activity Relationship; Thiazoles; Thrombin; Thromboplastin

2003
Assessment of bleeding propensity in non-human primates by combination of selective tissue factor/VIIa inhibition and aspirin compared to warfarin and aspirin treatment.
    Pharmacology, 2004, Volume: 70, Issue:2

    Topics: Aminobenzoates; Animals; Anticoagulants; Aspirin; Bleeding Time; Dose-Response Relationship, Drug; Drug Combinations; Factor VIIa; Hemorrhage; Macaca fascicularis; Male; Platelet Aggregation Inhibitors; Prothrombin Time; Pyrazines; Thromboplastin; Warfarin; Whole Blood Coagulation Time

2004
[Effects of tetramethylpyrazine on thrombin-induced tissue factor expression in vascular endothelial cells].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2009, Volume: 29, Issue:8

    Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Endothelial Cells; Gene Expression Regulation; Humans; Pyrazines; RNA, Messenger; Thrombin; Thromboplastin; Time Factors

2009
Effect of ligustrazine on mice model of hepatic veno-occlusive disease induced by Gynura segetum.
    Journal of gastroenterology and hepatology, 2011, Volume: 26, Issue:6

    Topics: Animals; Asteraceae; Bilirubin; Biomarkers; Blotting, Western; Disease Models, Animal; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Early Growth Response Protein 1; Female; Gene Expression Regulation; Hepatic Veno-Occlusive Disease; Liver; Mice; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; Serum Albumin; Thromboplastin; Time Factors; Transaminases; Transcription Factor RelA

2011
[Screening drugs for regulating tissue factor gene expression].
    Zhongguo shi yan xue ye xue za zhi, 2011, Volume: 19, Issue:1

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Drug Screening Assays, Antitumor; Gene Expression; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Pyrazines; Thromboplastin; Transcription Factors; Transcriptional Activation; U937 Cells

2011
Activation of coagulation by lenalidomide-based regimens for the treatment of multiple myeloma.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Blood Coagulation; Boronic Acids; Bortezomib; Cell Line; Cell Line, Tumor; Dexamethasone; Humans; Lenalidomide; Multiple Myeloma; Phosphatidylserines; Pyrazines; Thalidomide; Thromboplastin

2013