Page last updated: 2024-08-21

pyrazines and threonine

pyrazines has been researched along with threonine in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (6.25)18.2507
2000's4 (25.00)29.6817
2010's8 (50.00)24.3611
2020's3 (18.75)2.80

Authors

AuthorsStudies
Shu, CK1
Biggs, JR; Garcia, M; Kraft, AS; Peterson, LF; Zhang, DE; Zhang, Y1
Morris, AP; Sellin, JH; Umar, S; Wang, Y1
Ludwig, A; Meiners, S; Stangl, K; Stangl, V1
Allievi, C; Berkers, C; Bernareggi, A; Bussolati, B; Camussi, G; Cassin, M; Coscia, M; Costa, G; de Feudis, P; di Giovine, S; Ferracini, R; Ferrero, D; Giai, V; Hunter, K; Inghirami, G; Jones-Bolin, S; Massaia, M; Neri, A; Nicoli, P; Ovaa, H; Palumbo, A; Peola, S; Pescalli, N; Pezzoni, G; Piva, R; Roato, I; Ruggeri, B; Strepponi, I; Tamagno, I; Williams, M; Zhao, H1
Berenson, JR; Bonavida, B; Chen, H; Li, M; Li, ZW; Sanchez, E; Shen, J; Steinberg, JA; Wang, C1
Kay, LE; Ruschak, AM; Schimmer, AD; Slassi, M1
Appel, A1
Gallastegui, N; Groll, M1
Hu, Y; Wu, P; Zhang, J1
Camidge, DR; Ching, KA; Christensen, JG; Clark, JW; Diamond, JR; Eckhardt, SG; Kanteti, R; Lira, ME; LoRusso, PM; Salgia, R; Schoenmakers, EF; Varella-Garcia, M; Wilner, K; Xu, LG1
Clardy, J; Currie, CR; Nascimento, FS; Paludo, CR; Pupo, MT; Ruzzini, AC; Silva-Junior, EA1
Cao, Y; Tong, J; Xu, Y; Zhang, L1
Liu, L; Xu, J; Yu, H; Zhang, W1
Hu, M; Rao, Z; Shao, M; Xu, M; Yang, C; Yang, T; Yi, G; You, J; Zhang, R; Zhang, X1
Berglöf, A; Estupiñán, HY; Mohammad, DK; Schaafsma, GCP; Shi, Y; Smith, CIE; Vihinen, M; Wang, Q; Yu, L; Zain, R; Zhou, L1

Reviews

3 review(s) available for pyrazines and threonine

ArticleYear
Proteasome inhibitors: poisons and remedies.
    Medicinal research reviews, 2008, Volume: 28, Issue:2

    Topics: Binding Sites; Boronic Acids; Bortezomib; Dose-Response Relationship, Drug; Endothelium, Vascular; Humans; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Threonine

2008
Novel proteasome inhibitors to overcome bortezomib resistance.
    Journal of the National Cancer Institute, 2011, Jul-06, Volume: 103, Issue:13

    Topics: Allosteric Site; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line, Tumor; Chloroquine; Clioquinol; Drug Resistance, Neoplasm; Humans; Hydroxyquinolines; Lactones; Neoplasms; Oligopeptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Threonine; Ubiquitinated Proteins; Ubiquitination

2011
Clinical and marketed proteasome inhibitors for cancer treatment.
    Current medicinal chemistry, 2013, Volume: 20, Issue:20

    Topics: Boron Compounds; Boronic Acids; Bortezomib; Glycine; Humans; Lactones; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Structure-Activity Relationship; Threonine

2013

Other Studies

13 other study(ies) available for pyrazines and threonine

ArticleYear
Pyrazine formation from serine and threonine.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:10

    Topics: Flame Ionization; Food Preservation; Gas Chromatography-Mass Spectrometry; Hot Temperature; Humans; Pyrazines; Serine; Threonine

1999
Phosphorylation of AML1/RUNX1 regulates its degradation and nuclear matrix association.
    Molecular cancer research : MCR, 2005, Volume: 3, Issue:7

    Topics: Animals; Boronic Acids; Bortezomib; Core Binding Factor Alpha 2 Subunit; DNA-Binding Proteins; Immunoprecipitation; Mice; Mice, Knockout; Mutation; Nuclear Matrix; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins; Pyrazines; Serine; Threonine; Transcription Factors; Transcription, Genetic; Ubiquitin

2005
Dual alterations in casein kinase I-epsilon and GSK-3beta modulate beta-catenin stability in hyperproliferating colonic epithelia.
    American journal of physiology. Gastrointestinal and liver physiology, 2007, Volume: 292, Issue:2

    Topics: Animals; Axin Protein; beta Catenin; Boronic Acids; Bortezomib; Casein Kinase 1 epsilon; Cell Nucleus; Citrobacter rodentium; Colon; Cyclic AMP Response Element-Binding Protein; Cytoskeleton; DNA; Enterobacteriaceae Infections; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperplasia; Immunoprecipitation; Intestinal Mucosa; Mice; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Kinase C; Pyrazines; Repressor Proteins; Serine; TCF Transcription Factors; Threonine; Transcription Factor 7-Like 2 Protein

2007
CEP-18770: A novel, orally active proteasome inhibitor with a tumor-selective pharmacologic profile competitive with bortezomib.
    Blood, 2008, Mar-01, Volume: 111, Issue:5

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Cell Line; Cell Proliferation; Cell Survival; Drug Screening Assays, Antitumor; Endothelial Cells; Enzyme Inhibitors; Humans; Macrophage Colony-Stimulating Factor; Mice; Mice, Nude; Multiple Myeloma; Neoplasms; NF-kappa B; Osteogenesis; Proteasome Inhibitors; Pyrazines; RANK Ligand; Threonine; Treatment Outcome; Ubiquitin; Xenograft Model Antitumor Assays

2008
The proteasome inhibitor CEP-18770 enhances the anti-myeloma activity of bortezomib and melphalan.
    British journal of haematology, 2010, Volume: 148, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Death; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Male; Melphalan; Mice; Mice, SCID; Multiple Myeloma; Proteasome Inhibitors; Pyrazines; Threonine; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2010
Drugs: More shots on target.
    Nature, 2011, Dec-14, Volume: 480, Issue:7377

    Topics: Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Clinical Trials as Topic; Drug Resistance, Neoplasm; Glycine; Humans; Immunologic Factors; Lenalidomide; Multiple Myeloma; Oligopeptides; Protease Inhibitors; Pyrazines; Survival Rate; Thalidomide; Threonine

2011
Analysing properties of proteasome inhibitors using kinetic and X-ray crystallographic studies.
    Methods in molecular biology (Clifton, N.J.), 2012, Volume: 832

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Lactones; Multiple Myeloma; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Saccharomyces cerevisiae; Threonine

2012
Initial clinical sensitivity and acquired resistance to MET inhibition in MET-mutated papillary renal cell carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2013, Jun-01, Volume: 31, Issue:16

    Topics: Antineoplastic Agents; Biopsy; Carcinoma, Renal Cell; Disease Progression; Drug Resistance, Neoplasm; Heterozygote; Humans; In Situ Hybridization, Fluorescence; Kidney Neoplasms; Male; Methionine; Middle Aged; Point Mutation; Proto-Oncogene Proteins c-met; Pyrazines; Receptor Protein-Tyrosine Kinases; Sequence Analysis, DNA; Threonine; Treatment Failure; Triazoles

2013
Pyrazines from bacteria and ants: convergent chemistry within an ecological niche.
    Scientific reports, 2018, 02-07, Volume: 8, Issue:1

    Topics: Animals; Ants; Ecosystem; Gas Chromatography-Mass Spectrometry; Pheromones; Pyrazines; Serratia marcescens; Sodium Acetate; Threonine

2018
An Alkylpyrazine Synthesis Mechanism Involving l-Threonine-3-Dehydrogenase Describes the Production of 2,5-Dimethylpyrazine and 2,3,5-Trimethylpyrazine by Bacillus subtilis.
    Applied and environmental microbiology, 2019, 12-15, Volume: 85, Issue:24

    Topics: Acetone; Acetyl Coenzyme A; Acetyltransferases; Alcohol Oxidoreductases; Bacillus subtilis; Catalysis; Flavoring Agents; Glycine; Pyrazines; Threonine

2019
[Biosynthesis of 2,5-dimethylpyrazine from L-threonine by whole-cell biocatalyst of recombinant Escherichia coli].
    Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2021, Jan-25, Volume: 37, Issue:1

    Topics: Escherichia coli; Lactococcus; Metabolic Engineering; Pyrazines; Threonine

2021
Redistribution of Intracellular Metabolic Flow in
    Journal of agricultural and food chemistry, 2021, Mar-03, Volume: 69, Issue:8

    Topics: Carbon; Escherichia coli; Metabolic Engineering; Pyrazines; Threonine

2021
BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib.
    Leukemia, 2021, Volume: 35, Issue:5

    Topics: Adenine; Agammaglobulinaemia Tyrosine Kinase; Animals; Benzamides; Cell Line; Cell Line, Tumor; Chickens; Chlorocebus aethiops; COS Cells; Cysteine; Drug Resistance, Neoplasm; HEK293 Cells; Humans; Mutation; Piperidines; Protein Kinase Inhibitors; Pyrazines; Pyrazoles; Pyrimidines; Threonine

2021