pyrazines has been researched along with thapsigargin in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (63.64) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abbruzzese, JL; Boise, LH; Carew, JS; Chiao, PJ; Dunner, K; Huang, P; McConkey, DJ; Nawrocki, ST | 1 |
| Abbruzzese, JL; Carew, JS; Dunner, K; Highshaw, RA; Huang, P; McConkey, DJ; Nawrocki, ST; Pino, MS | 1 |
| Chan, HC; Chung, YW; Connie Wong, HY; Yang, N; Zhang, GH; Zhu, JX | 1 |
| Reilly, CA; Sabnis, AS; Shadid, M; Yost, GS | 1 |
| Fels, DR; Koong, AC; Koumenis, C; Kridel, SJ; Olson, M; Segan, AT; Spiotto, M; Ye, J | 1 |
| Chen, L; Chen, X; Dong, B; Dong, H; Gao, G; Gao, Y; Gu, H | 1 |
| Benavides, A; Frost, P; Hoang, B; Lichtenstein, A; Shi, Y | 1 |
| Ambinder, RF; Chen, J; Hayward, SD; Li, H; Shamay, M; Shirley, CM; Zahnow, CA | 1 |
| Chen, L; Huang, F; Li, W; Li, X; Liu, Z; Luo, Z; Wu, H; Xu, Y; Young, C; Zhou, S | 1 |
| Cheng, Y; Harvey, H; Huber-Keener, KJ; Jefferson, LS; Kimball, SR; Ren, X; Shan, Y; Yang, JM; Zhang, L; Zhang, Y | 1 |
| Bodeen, WJ; Han, YG; Marada, S; Ogden, SK; Stewart, DP | 1 |
11 other study(ies) available for pyrazines and thapsigargin
| Article | Year |
|---|---|
Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Boronic Acids; Bortezomib; Calcium; Caspase Inhibitors; Caspases; Caspases, Initiator; Cycloheximide; eIF-2 Kinase; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Heat-Shock Proteins; Humans; Molecular Chaperones; Oxidative Stress; Pancreas; Pancreatic Neoplasms; Phosphorylation; Protein Biosynthesis; Protein Processing, Post-Translational; Pyrazines; RNA, Small Interfering; Thapsigargin; Transcription Factor CHOP; Ubiquitin | 2005 |
Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Calcium; Carcinogens; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cisplatin; Cytochromes c; Drug Interactions; Endoplasmic Reticulum; Enzyme Activation; Humans; Immunoblotting; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Pyrazines; RNA, Small Interfering; Thapsigargin; Tumor Stem Cell Assay; Tunicamycin | 2005 |
Involvement of intracellular and extracellular Ca2+ in tetramethylpyrazine-induced colonic anion secretion.
Topics: Adenosine Triphosphate; Anions; Caco-2 Cells; Calcium; Calcium Signaling; Colon; Humans; Intestinal Mucosa; Pyrazines; Thapsigargin | 2006 |
Human lung epithelial cells express a functional cold-sensing TRPM8 variant.
Topics: Amino Acid Sequence; Animals; Bronchi; Capsaicin; Cell Line; Cold Temperature; Cytokines; Endoplasmic Reticulum; Epithelial Cells; Humans; Lung; Menthol; Molecular Sequence Data; Pyrazines; Pyridines; Thapsigargin; Thermoreceptors; Thermosensing; TRPM Cation Channels | 2008 |
Preferential cytotoxicity of bortezomib toward hypoxic tumor cells via overactivation of endoplasmic reticulum stress pathways.
Topics: Activating Transcription Factor 4; Antineoplastic Agents; Apoptosis; Autophagy; Boronic Acids; Bortezomib; Cell Hypoxia; Cell Line, Tumor; DNA-Binding Proteins; Endoplasmic Reticulum; Humans; Microtubule-Associated Proteins; Necrosis; Protease Inhibitors; Protein Folding; Pyrazines; Regulatory Factor X Transcription Factors; Signal Transduction; Stress, Physiological; Thapsigargin; Transcription Factors | 2008 |
Dysregulation of unfolded protein response partially underlies proapoptotic activity of bortezomib in multiple myeloma cells.
Topics: Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Brefeldin A; Cell Line, Tumor; Cell Proliferation; DNA-Binding Proteins; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Gene Expression; Heat-Shock Proteins; Humans; Protease Inhibitors; Pyrazines; Regulatory Factor X Transcription Factors; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Thapsigargin; Transcription Factor CHOP; Transcription Factors; X-Box Binding Protein 1 | 2009 |
Effect of autophagy on multiple myeloma cell viability.
Topics: Adenine; Antifungal Agents; Antimalarials; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Boronic Acids; Bortezomib; Cell Proliferation; Chloroquine; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Immunoblotting; Membrane Proteins; Microscopy, Fluorescence; Multiple Myeloma; Pyrazines; RNA, Small Interfering; Sirolimus; Thapsigargin; Tumor Cells, Cultured | 2009 |
Bortezomib induction of C/EBPβ mediates Epstein-Barr virus lytic activation in Burkitt lymphoma.
Topics: Activating Transcription Factor 4; Activating Transcription Factor 6; Antineoplastic Agents; Boronic Acids; Bortezomib; Burkitt Lymphoma; CCAAT-Enhancer-Binding Protein-beta; Cell Line, Tumor; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Viral; HEK293 Cells; Herpesvirus 4, Human; Humans; Pyrazines; Regulatory Factor X Transcription Factors; Response Elements; Thapsigargin; Trans-Activators; Transcription Factor CHOP; Transcription Factors; Unfolded Protein Response; Virus Activation; X-Box Binding Protein 1 | 2011 |
The novel compound liguzinediol exerts positive inotropic effects in isolated rat heart via sarcoplasmic reticulum Ca2+ ATPase-dependent mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart; Male; Myocardial Contraction; Myocytes, Cardiac; Nimodipine; Ouabain; Prazosin; Propranolol; Pyrazines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin | 2012 |
Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells.
Topics: Apoptosis; Autophagy; Boronic Acids; Bortezomib; Cell Line, Tumor; Cell Lineage; Curcumin; Elongation Factor 2 Kinase; Endoplasmic Reticulum Stress; Enzyme Activation; Gene Silencing; Humans; Models, Biological; Phosphorylation; Phosphoserine; Pyrazines; Thapsigargin; Transcription Factors; Tunicamycin | 2013 |
The unfolded protein response selectively targets active smoothened mutants.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Benzoquinones; Boronic Acids; Bortezomib; Carcinoma, Basal Cell; Cell Line; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Enzyme Inhibitors; Green Fluorescent Proteins; Hedgehog Proteins; Heterocyclic Compounds, 4 or More Rings; HSP90 Heat-Shock Proteins; Lactams, Macrocyclic; Medulloblastoma; Mice; Mutant Proteins; Pyrazines; Receptors, G-Protein-Coupled; RNA Interference; RNA, Small Interfering; Signal Transduction; Smoothened Receptor; Thapsigargin; Ubiquitin-Protein Ligases; Unfolded Protein Response | 2013 |