Page last updated: 2024-08-21

pyrazines and tak 029

pyrazines has been researched along with tak 029 in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (75.00)18.2507
2000's2 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukushi, H; Imura, Y; Kawamura, M; Kita, S; Moriya, N; Nishikawa, K; Sugihara, H; Terashita, Z1
Kawamura, M; Moriya, N; Terashita, Z; Tsuji, N1
Iwasa, S; Kurokawa, T; Miyazaki, K; Ogawa, Y; Takada, S1
Fujisawa, Y; Fukushi, H; Imai, Y; Kawamura, M; Kita, S; Miyawaki, T; Sugihara, H; Terashita, Z1
Fujimura, A; Fuse, K; Kawahito, K; Kobayashi, E; Misawa, Y1
Coleman, JC; Coller, BS; Hillman, RS; Lee, TT; Lincoff, AM; Smith, JW; Steinhubl, SR1
Abe, T; Fukuuchi, Y; Inoue, K; Satoh, H; Tanahashi, N; Tomita, M; Tomita, Y1
Affeld, K; Dohmen, PM; Kertzscher, U; Konertz, W; Linneweber, J1

Other Studies

8 other study(ies) available for pyrazines and tak 029

ArticleYear
Antithrombotic effects of TAK-029, a novel GPIIb/IIIa antagonist, in guinea pigs: comparative studies with ticlopidine, clopidogrel, aspirin, prostaglandin E1 and argatroban.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 277, Issue:1

    Topics: Alprostadil; Animals; Arginine; Aspirin; Clopidogrel; Dogs; Fibrinolytic Agents; Guanidines; Guinea Pigs; Humans; Macaca fascicularis; Male; Pipecolic Acids; Platelet Adhesiveness; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrazines; Sulfonamides; Ticlopidine

1996
Effects of TAK-029, a novel GPIIb/IIIa antagonist, on arterial thrombosis in guinea pigs, dogs and monkeys.
    Thrombosis research, 1997, May-15, Volume: 86, Issue:4

    Topics: Animals; Basilar Artery; Bleeding Time; Carotid Artery Thrombosis; Coronary Thrombosis; Disease Models, Animal; Dogs; Female; Guanidines; Guinea Pigs; Injections, Intravenous; Macaca fascicularis; Male; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrazines; Thrombosis

1997
Utilization of an amorphous form of a water-soluble GPIIb/IIIa antagonist for controlled release from biodegradable microspheres.
    Pharmaceutical research, 1997, Volume: 14, Issue:9

    Topics: Animals; Arginine; Biocompatible Materials; Drug Delivery Systems; Fibrinolytic Agents; Guanidines; Lactic Acid; Male; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pyrazines; Rats; Rats, Sprague-Dawley

1997
Novel non-peptide fibrinogen receptor antagonists. 1. Synthesis and glycoprotein IIb-IIIa antagonistic activities of 1,3,4-trisubstituted 2-oxopiperazine derivatives incorporating side-chain functions of the RGDF peptide.
    Journal of medicinal chemistry, 1998, Feb-12, Volume: 41, Issue:4

    Topics: Animals; Drug Design; Fibrinogen; Guanidines; Guinea Pigs; Humans; In Vitro Techniques; Kinetics; Molecular Structure; Oligopeptides; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrazines; Structure-Activity Relationship

1998
Platelet protective effect of TAK-029, a novel glycoprotein IIb/IIIa antagonist: an in vitro study.
    Artificial organs, 1998, Volume: 22, Issue:4

    Topics: beta-Thromboglobulin; Blood Platelets; Cardiopulmonary Bypass; Centrifugation; Fibrinolytic Agents; Guanidines; Humans; In Vitro Techniques; Models, Biological; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrazines; Stress, Mechanical

1998
Rapid platelet-function assay: an automated and quantitative cartridge-based method.
    Circulation, 1999, Feb-09, Volume: 99, Issue:5

    Topics: Abciximab; Adenosine Diphosphate; Antibodies, Monoclonal; Autoanalysis; Guanidines; Humans; Immunoglobulin Fab Fragments; Nephelometry and Turbidimetry; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrazines; Radiometry; Time Factors

1999
Adhesion of adenosine diphosphate-activated platelets to human brain microvascular endothelial cells under flow in vitro is mediated via GPIIb/IIIa.
    Neuroscience letters, 2001, Mar-23, Volume: 301, Issue:1

    Topics: Adenosine Diphosphate; Brain; Cells, Cultured; Endothelium, Vascular; Fibrinolytic Agents; Guanidines; Humans; Microcirculation; Platelet Adhesiveness; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrazines

2001
Local glycoprotein IIb/IIIa receptor inhibitor delivery from the pump surface attenuates platelet adhesion in continuous flow ventricular assist devices.
    Artificial organs, 2008, Volume: 32, Issue:10

    Topics: Adsorption; Blood Platelets; Delayed-Action Preparations; Fibrinogen; Guanidines; Heart-Assist Devices; Hemorheology; Humans; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyrazines

2008