Page last updated: 2024-08-21

pyrazines and t 1105

pyrazines has been researched along with t 1105 in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (10.00)29.6817
2010's5 (50.00)24.3611
2020's4 (40.00)2.80

Authors

AuthorsStudies
Barnard, DL; Furuta, Y; Gowen, BB; Julander, JG; Morrey, JD; Sakamoto, K; Shiraki, K; Smee, DF; Takahashi, K1
Billiet, A; De Clercq, K; De Vleeschauwer, AR; Goris, N; Lefebvre, DJ; Murao, LE; Neyts, J; Paul, G; Willems, T1
Bei, Z; Cai, L; Dou, Y; Song, Y; Sun, Y; Wang, H; Xu, L; Zhang, D1
Bonnac, LF; Geraghty, RJ; Patterson, SE; Qiu, L1
Huchting, J; Meier, C; Naesens, L; Nasser, H; Vanderlinden, E; Winkler, M1
Huchting, J; Meier, C; Naesens, L; Van Berwaer, R; Vanderlinden, E1
Canard, B; Coutard, B; Decroly, E; Fattorini, V; Ferron, F; Huchting, J; Le, NT; Meier, C; Peersen, O; Piorkowski, G; Selisko, B; Shannon, A; Touret, F1
Chen, YC; Ho, YJ; Huang, CK; Lin, KC; Lu, JW1
Bonnac, LF; Cheeran, MC; Dreis, CD; Edwards, TC; Geraghty, RJ; Krishna, VD; Qiu, L; Soto-Acosta, R; Xie, J1
Fukai, K; Furuta, Y; Ikezawa, M; Kawaguchi, R; Komeno, T; Kurosaki, C; Masujin, K; Morioka, K; Nakajima, N; Nishi, T; Sakamoto, K; Sugihara, H; Yamada, M1

Reviews

1 review(s) available for pyrazines and t 1105

ArticleYear
T-705 (favipiravir) and related compounds: Novel broad-spectrum inhibitors of RNA viral infections.
    Antiviral research, 2009, Volume: 82, Issue:3

    Topics: Amides; Animals; Antiviral Agents; Nucleosides; Pyrazines; RNA Virus Infections; RNA Viruses; RNA-Dependent RNA Polymerase; Viral Proteins

2009

Other Studies

9 other study(ies) available for pyrazines and t 1105

ArticleYear
A Refined Guinea Pig Model of Foot-and-Mouth Disease Virus Infection for Assessing the Efficacy of Antiviral Compounds.
    Transboundary and emerging diseases, 2016, Volume: 63, Issue:2

    Topics: Animals; Antibodies, Viral; Antiviral Agents; Disease Models, Animal; Europe; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Guinea Pigs; Pyrazines; RNA, Viral; Vaccination; Viral Vaccines

2016
Viral polymerase inhibitors T-705 and T-1105 are potential inhibitors of Zika virus replication.
    Archives of virology, 2017, Volume: 162, Issue:9

    Topics: Amides; Animals; Antiviral Agents; Cell Survival; Chlorocebus aethiops; Dose-Response Relationship, Drug; Molecular Structure; Pyrazines; Vero Cells; Virus Replication; Zika Virus

2017
Nucleobases and corresponding nucleosides display potent antiviral activities against dengue virus possibly through viral lethal mutagenesis.
    PLoS neglected tropical diseases, 2018, Volume: 12, Issue:4

    Topics: Amides; Antiviral Agents; Dengue; Dengue Virus; Humans; Mutagenesis; Mutation; Nucleosides; Pyrazines; Virus Replication

2018
Prodrugs of the Phosphoribosylated Forms of Hydroxypyrazinecarboxamide Pseudobase T-705 and Its De-Fluoro Analogue T-1105 as Potent Influenza Virus Inhibitors.
    Journal of medicinal chemistry, 2018, Jul-26, Volume: 61, Issue:14

    Topics: Amides; Animals; Antiviral Agents; Dogs; Madin Darby Canine Kidney Cells; Orthomyxoviridae; Prodrugs; Pyrazines; Ribonucleotides

2018
Cell line-dependent activation and antiviral activity of T-1105, the non-fluorinated analogue of T-705 (favipiravir).
    Antiviral research, 2019, Volume: 167

    Topics: Amides; Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Dogs; HEK293 Cells; Humans; Madin Darby Canine Kidney Cells; Pyrazines; Ribonucleosides; RNA Viruses; Vero Cells

2019
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis.
    Nature communications, 2020, 09-17, Volume: 11, Issue:1

    Topics: Amides; Animals; Antiviral Agents; Betacoronavirus; Chlorocebus aethiops; Coronavirus Infections; Coronavirus RNA-Dependent RNA Polymerase; COVID-19; COVID-19 Drug Treatment; Models, Molecular; Mutagenesis; Pandemics; Pneumonia, Viral; Pyrazines; RNA-Dependent RNA Polymerase; RNA, Viral; SARS-CoV-2; Sequence Analysis; Vero Cells; Viral Nonstructural Proteins; Virus Replication

2020
Synergistic in-vitro antiviral effects of combination treatment using anidulafungin and T-1105 against Zika virus infection.
    Antiviral research, 2021, Volume: 195

    Topics: Anidulafungin; Animals; Antiviral Agents; Chlorocebus aethiops; Drug Synergism; Humans; Inhibitory Concentration 50; Pyrazines; RNA, Viral; Vero Cells; Virion; Virus Attachment; Zika Virus; Zika Virus Infection

2021
Enhancing the Antiviral Potency of Nucleobases for Potential Broad-Spectrum Antiviral Therapies.
    Viruses, 2021, 12-14, Volume: 13, Issue:12

    Topics: Adenosine Triphosphate; Amides; Animals; Antimetabolites; Antiviral Agents; Cell Line; Drug Synergism; Guanosine Triphosphate; Humans; Methylthioinosine; Mutation; Phosphoribosyl Pyrophosphate; Pyrazines; RNA Viruses; RNA, Viral; Virus Replication

2021
Administration of the antiviral agent T-1105 fully protects pigs from foot-and-mouth disease infection.
    Antiviral research, 2022, Volume: 208

    Topics: Animals; Antiviral Agents; Foot-and-Mouth Disease; Foot-and-Mouth Disease Virus; Pyrazines; Swine

2022