pyrazines has been researched along with stilbenes in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (4.55) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (31.82) | 29.6817 |
| 2010's | 14 (63.64) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perry, SF; Randall, DJ | 1 |
| Adams, J; Elliott, PJ | 1 |
| Cherrington, NJ; Klaassen, CD; Maher, JM; Slitt, AL | 1 |
| Aggarwal, BB; Bhardwaj, A; Bueso-Ramos, C; Gaur, U; Nair, AS; Sethi, G; Shishodia, S; Takada, Y; Vadhan-Raj, S | 1 |
| Chan, TH; Chen, D; Dou, QP; Landis-Piwowar, KR; Milacic, V; Yan, B; Yang, H; Zhao, Y | 1 |
| Chapple, S; Collins, C; Fairman, DA | 1 |
| Anderson, KC; Ciccarelli, B; Dammacco, F; Ghobrial, IM; Hatjiharissi, E; Jia, X; Leleu, X; Moreau, AS; Ngo, HT; Patterson, CJ; Roccaro, AM; Russo, D; Sacco, A; Treon, SP; Vacca, A; Xu, L | 1 |
| Gajate, C; Mollinedo, F; Reis-Sobreiro, M | 1 |
| Resmi, H | 1 |
| Kupisiewicz, K | 1 |
| Chen, H; Deng, L; Guo, X; Liu, X; Song, Y; Wu, J; Zhai, L; Zhan, P | 1 |
| Guo, XL; Liu, WG; Liu, XY; Sun, RY; Zhai, L; Zhang, P | 1 |
| Cavenagh, J; Cook, G; Cook, M; Davies, F; Elliott, P; Gumbleton, T; Jacobson, E; Oakervee, H; Plesner, T; Popat, R | 1 |
| Chen, S; Li, Z; Ma, X; Pan, J; Zheng, Z | 1 |
| El-Shentenawy, A; Mohammed, AA | 1 |
| Hoseki, J; Maharjan, S; Oku, M; Sakai, Y; Tsuda, M | 1 |
| Blondiaux, J; Haque, A; Hober, D | 1 |
| Ding, Y; He, X; Liao, W; Lu, Q; Xiang, W | 1 |
| Ding, Y; Gao, H; Liao, W; Sun, X; Wang, J; Wang, M; Wang, P; Xu, C; Zhong, Y | 1 |
| Chen, L; Liu, J; Liu, T; Wang, Q | 1 |
| Li, J; Li, ZF; Zhang, J; Zhang, S; Zhou, R | 1 |
| Jiao, Y; Liu, H; Peng, C; Su, G; Zhang, S; Zhu, Y | 1 |
6 review(s) available for pyrazines and stilbenes
| Article | Year |
|---|---|
New agents in cancer clinical trials.
Topics: Antineoplastic Agents; Benzamides; Benzoquinones; Boronic Acids; Bortezomib; Clinical Trials as Topic; Dioxoles; Enzyme Inhibitors; Humans; Hydroxamic Acids; Imatinib Mesylate; Isoquinolines; Lactams, Macrocyclic; Neoplasms; Piperazines; Pyrazines; Pyrimidines; Rifabutin; Stilbenes; Tetrahydrofolates; Tetrahydroisoquinolines; Trabectedin; Vorinostat | 2000 |
The proteasome as a potential target for novel anticancer drugs and chemosensitizers.
Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Catechin; Clinical Trials as Topic; Curcumin; Drug Resistance, Neoplasm; Drug Therapy, Combination; Genistein; Humans; Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Structure-Activity Relationship; Ubiquitin | 2006 |
Biological aspects of altered bone remodeling in multiple myeloma and possibilities of pharmacological intervention.
Topics: Antineoplastic Agents, Phytogenic; Bone and Bones; Bone Remodeling; Bone Resorption; Boronic Acids; Bortezomib; Calcium-Binding Proteins; Humans; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Multiple Myeloma; Osteoblasts; Osteoclasts; Protease Inhibitors; Pyrazines; Resveratrol; Signal Transduction; Stilbenes; Wnt Proteins | 2011 |
Advanced thyroid cancers: new era of treatment.
Topics: Anilides; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Differentiation; Cell Proliferation; ErbB Receptors; Genetic Therapy; Histone Deacetylase Inhibitors; Humans; Immunotherapy; Lithium; Molecular Targeted Therapy; Piperidines; Protein Kinase Inhibitors; Pyrazines; Pyridines; Quinazolines; Stilbenes; Thalidomide; Thyroid Neoplasms | 2014 |
Addressing Therapeutic Options for Ebola Virus Infection in Current and Future Outbreaks.
Topics: Amides; Amidines; Androstenes; Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antiviral Agents; Benzofurans; Cytosine; Disease Models, Animal; Disease Outbreaks; Ebolavirus; Hemorrhagic Fever, Ebola; Humans; Immune Sera; Organophosphonates; Pyrazines; RNA, Small Interfering; Stilbenes; Virus Replication | 2015 |
Perspectives of traditional Chinese medicine in pancreas protection for acute pancreatitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Apigenin; Artemisinins; Drugs, Chinese Herbal; Emodin; Flavanones; Glucuronates; Humans; Medicine, Chinese Traditional; Pancreas; Pancreatitis; Patient Safety; Phytotherapy; Plant Extracts; Pyrazines; Resveratrol; Rheum; Salvia miltiorrhiza; Stilbenes; Sulfates | 2017 |
1 trial(s) available for pyrazines and stilbenes
| Article | Year |
|---|---|
A phase 2 study of SRT501 (resveratrol) with bortezomib for patients with relapsed and or refractory multiple myeloma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Boronic Acids; Bortezomib; Creatinine; Dehydration; Drug Resistance, Neoplasm; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Multiple Myeloma; Pyrazines; Recurrence; Remission Induction; Resveratrol; Salvage Therapy; Stilbenes; Treatment Failure; Vomiting | 2013 |
15 other study(ies) available for pyrazines and stilbenes
| Article | Year |
|---|---|
Effects of amiloride and SITS on branchial ion fluxes in rainbow trout, Salmo gairdneri.
Topics: 4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid; Amiloride; Animals; Biological Transport; Chlorides; Epithelium; Gills; Hydrogen-Ion Concentration; Pyrazines; Stilbenes; Trout | 1981 |
Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites.
Topics: Acetaminophen; Allyl Compounds; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Branched DNA Signal Amplification Assay; Drug Resistance, Multiple; Kidney; Liver; Male; Mitochondrial Proteins; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Ribosomal Proteins; RNA, Messenger; Saccharomyces cerevisiae Proteins; Stilbenes; Sulfides; Thiones; Thiophenes; Time Factors | 2003 |
Resveratrol inhibits proliferation, induces apoptosis, and overcomes chemoresistance through down-regulation of STAT3 and nuclear factor-kappaB-regulated antiapoptotic and cell survival gene products in human multiple myeloma cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Boronic Acids; Bortezomib; Caspase 3; Cell Proliferation; Cell Survival; Down-Regulation; Drug Resistance, Neoplasm; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Interleukin-6; Multiple Myeloma; NF-kappa B; Proto-Oncogene Proteins c-akt; Pyrazines; Resveratrol; STAT3 Transcription Factor; Stilbenes; Syndecan-1; Thalidomide; Tumor Cells, Cultured | 2007 |
Progress curve analysis of CYP1A2 inhibition: a more informative approach to the assessment of mechanism-based inactivation?
Topics: Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Dihydralazine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Interactions; Enzyme Inhibitors; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Models, Biological; NADP; Paroxetine; Pyrazines; Resveratrol; Stilbenes; Theophylline; Thiones; Thiophenes | 2007 |
Resveratrol exerts antiproliferative activity and induces apoptosis in Waldenström's macroglobulinemia.
Topics: Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; beta Catenin; Boronic Acids; Bortezomib; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; Dexamethasone; Drug Evaluation, Preclinical; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Leukocytes; Oligonucleotide Array Sequence Analysis; Pyrazines; Resveratrol; Signal Transduction; Stilbenes; TCF Transcription Factors; Vidarabine; Waldenstrom Macroglobulinemia | 2008 |
Involvement of mitochondria and recruitment of Fas/CD95 signaling in lipid rafts in resveratrol-mediated antimyeloma and antileukemia actions.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Boronic Acids; Bortezomib; Caspase 10; Caspase 8; Cell Line, Tumor; Drug Synergism; fas Receptor; Fas-Associated Death Domain Protein; Flow Cytometry; Fluorescent Antibody Technique; Humans; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia, T-Cell; Membrane Microdomains; Microscopy, Confocal; Mitochondria; Multiple Myeloma; Phosphorylcholine; Pyrazines; Resveratrol; Signal Transduction; Stilbenes | 2009 |
The combination of bortezomib and resveratrol may prevent muscle wasting in diabetes.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Boronic Acids; Bortezomib; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Humans; Inflammation; Models, Biological; Muscular Atrophy; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrazines; Rats; Resveratrol; Stilbenes | 2011 |
Ligustrazine derivatives. Part 4: design, synthesis, and biological evaluation of novel ligustrazine-based stilbene derivatives as potential cardiovascular agents.
Topics: Cardiovascular Agents; Drug Design; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Oxidative Stress; Pyrazines; Stilbenes; Structure-Activity Relationship | 2012 |
Cytoprotective effects of CSTMP, a novel stilbene derivative, against H2O2-induced oxidative stress in human endothelial cells.
Topics: Antioxidants; Cells, Cultured; Cytoprotection; Dose-Response Relationship, Drug; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Oxidative Stress; Pyrazines; Stilbenes | 2011 |
Tetramethylpyrazine attenuates TNF-α-induced iNOS expression in human endothelial cells: Involvement of Syk-mediated activation of PI3K-IKK-IκB signaling pathways.
Topics: Cell Nucleus; Endothelial Cells; Endothelium, Vascular; Human Umbilical Vein Endothelial Cells; Humans; I-kappa B Kinase; I-kappa B Proteins; Intracellular Signaling Peptides and Proteins; NF-kappa B; Nitric Oxide Synthase Type II; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Proteolysis; Pyrazines; Signal Transduction; Stilbenes; Syk Kinase; Transcription, Genetic; Tumor Necrosis Factor-alpha | 2013 |
Mitochondrial impairment triggers cytosolic oxidative stress and cell death following proteasome inhibition.
Topics: Animals; Antioxidants; Apoptosis; Boronic Acids; Bortezomib; CHO Cells; Cricetinae; Cricetulus; Membrane Potential, Mitochondrial; Mitochondria; Neurodegenerative Diseases; Oxidative Stress; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proteolysis; Pyrazines; Reactive Oxygen Species; Resveratrol; Stilbenes; Ubiquitination | 2014 |
CSTMP Exerts Anti-Inflammatory Effects on LPS-Induced Human Renal Proximal Tubular Epithelial Cells by Inhibiting TLR4-Mediated NF-κB Pathways.
Topics: Active Transport, Cell Nucleus; Anti-Inflammatory Agents; Cells, Cultured; Epithelial Cells; Humans; Hydrogen Peroxide; I-kappa B Kinase; Inflammation Mediators; Interleukin-1 Receptor-Associated Kinases; Kidney Tubules, Proximal; Lipopolysaccharides; Lupus Nephritis; MAP Kinase Kinase Kinases; Myeloid Differentiation Factor 88; NF-kappa B; NF-kappa B p50 Subunit; NF-KappaB Inhibitor alpha; Oxidative Stress; Phosphorylation; Pyrazines; Stilbenes; TNF Receptor-Associated Factor 6; Toll-Like Receptor 4; Transcription Factor RelA | 2016 |
CSTMP induces apoptosis and mitochondrial dysfunction in human myeloma RPMI8226 cells via CHOP-dependent endoplasmic reticulum stress.
Topics: Apoptosis; Caspases; Cell Line, Tumor; Cell Survival; Cytochromes c; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Humans; Mitochondria; Multiple Myeloma; Pyrazines; Resveratrol; Stilbenes; Transcription Factor CHOP; Unfolded Protein Response | 2016 |
Anti-inflammatory effect of combined tetramethylpyrazine, resveratrol and curcumin in vivo.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Aspartate Aminotransferases; Cartilage; Curcumin; Cytokines; Drug Combinations; Edema; Female; Inflammation; Joints; Kidney; Liver; Male; Mice; NF-kappa B; Phytotherapy; Plant Extracts; Pyrazines; Rats, Sprague-Dawley; Resveratrol; Stilbenes | 2017 |
A newly synthesized Ligustrazine stilbene derivative inhibits PDGF-BB induced vascular smooth muscle cell phenotypic switch and proliferation via delaying cell cycle progression.
Topics: Actins; Animals; Becaplermin; Cell Cycle; Cell Proliferation; Gene Expression Regulation, Enzymologic; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Muscle, Smooth, Vascular; Osteopontin; Phenotype; Proto-Oncogene Proteins c-sis; Pyrazines; Rats; Rats, Sprague-Dawley; Stilbenes | 2017 |