Compounds > pyrazines
Page last updated: 2024-08-21

pyrazines and sitagliptin phosphate, metformin hydrochloride drug combination

pyrazines has been researched along with sitagliptin phosphate, metformin hydrochloride drug combination in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, RK; Neumiller, JJ; Reynolds, JK1
Gottesdiener, KM; Gutierrez, M; Johnson-Levonas, AO; Liu, Q; Matthews, CZ; Migoya, EM; Miller, JL; Wagner, JA; Zheng, W1
Scheen, AJ1
Scheen, AJ; Van Gaal, LF1

Reviews

1 review(s) available for pyrazines and sitagliptin phosphate, metformin hydrochloride drug combination

ArticleYear
Janumet: a combination product suitable for use in patients with Type 2 diabetes.
    Expert opinion on investigational drugs, 2008, Volume: 17, Issue:10

    Topics: Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Drug Interactions; Glucagon-Like Peptide 1; Humans; Hypoglycemic Agents; Metformin; Pyrazines; Sitagliptin Phosphate; Sitagliptin Phosphate, Metformin Hydrochloride Drug Combination; Triazoles

2008

Trials

1 trial(s) available for pyrazines and sitagliptin phosphate, metformin hydrochloride drug combination

ArticleYear
Bioequivalence of sitagliptin/metformin fixed-dose combination tablets and concomitant administration of sitagliptin and metformin in healthy adult subjects: a randomized, open-label, crossover study.
    Clinical drug investigation, 2010, Volume: 30, Issue:12

    Topics: Administration, Oral; Adult; Blood Glucose; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypoglycemic Agents; Male; Metformin; Middle Aged; Pyrazines; Sitagliptin Phosphate; Sitagliptin Phosphate, Metformin Hydrochloride Drug Combination; Tablets; Therapeutic Equivalency; Treatment Outcome; Triazoles; United States; Young Adult

2010

Other Studies

3 other study(ies) available for pyrazines and sitagliptin phosphate, metformin hydrochloride drug combination

ArticleYear
Sitagliptin + metformin: new combination. Do not use this combination. Sitagliptin provides a slight increase of glucose-lowering effects, but there is a disturbing potential for long-term adverse effects: infections, depression, and cancer.
    Prescrire international, 2009, Volume: 18, Issue:101

    Topics: Biguanides; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Approval; Drug Combinations; Drug Synergism; Europe; Humans; Hypoglycemic Agents; Metformin; Pyrazines; Sitagliptin Phosphate; Sitagliptin Phosphate, Metformin Hydrochloride Drug Combination; Sulfonylurea Compounds; Triazoles

2009
[Medication of the month. Sitagliptin-metformin fixed combination (Janumet)].
    Revue medicale de Liege, 2010, Volume: 65, Issue:11

    Topics: Diabetes Mellitus, Type 2; Drug Combinations; Humans; Hypoglycemic Agents; Metformin; Pyrazines; Sitagliptin Phosphate, Metformin Hydrochloride Drug Combination

2010
[Sitagliptin in the treatment of type 2 diabetes: insights five years after commercialisation].
    Revue medicale de Liege, 2013, Volume: 68, Issue:10

    Topics: Belgium; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hypoglycemic Agents; Metformin; Pyrazines; Renal Insufficiency; Sitagliptin Phosphate; Sitagliptin Phosphate, Metformin Hydrochloride Drug Combination; Triazoles

2013