pyrazines has been researched along with serine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Sänger, U; Ziegler, K | 1 |
| Shu, CK | 1 |
| Biggs, JR; Garcia, M; Kraft, AS; Peterson, LF; Zhang, DE; Zhang, Y | 1 |
| Birle, D; Degendorfer, P; Hedley, D; Mackay, H; Mackenzie, M; Major, P; Moore, M; Nicklee, T; Oza, A; Siu, L; Townsley, C; Tsao, MS; Vincent, M; Wright, J | 1 |
| Kim, SG; Lee, SJ | 1 |
| Morris, AP; Sellin, JH; Umar, S; Wang, Y | 1 |
| Adams, A; De Kimpe, N; Van Lancker, F | 1 |
| Cheng, Y; Gong, JB; Jiang, SS; Lv, L; Xu, J | 1 |
| Bassell, GJ; Gross, C; Muddashetty, RS; Nalavadi, VC | 1 |
| Akahoshi, F; Ishii, S; Kadowaki, T; Kishida, H; Miyaguchi, I; Nabeno, M; Tanaka, Y | 1 |
| Cui, YJ; Fei, HR; Li, ZM; Sun, BL; Sun, YK; Wang, FZ; Wang, XY; Yang, XY; Zhang, JG | 1 |
| Dai, X; Foretz, M; Liu, J; Liu, Z; Lu, Q; Ouyang, C; Song, P; Viollet, B; Wu, J; Wu, Y; Xie, Z; Yuan, Z; Zhang, W; Zhao, Z; Zhuo, X; Zou, MH | 1 |
| Faggi, C; Innocenti, R; Lenci, E; Menchi, G; Trabocchi, A | 1 |
| Abdel-Fatah, TM; Aleskandarany, MA; Alsubhi, N; Arora, A; Chan, SY; Curtin, NJ; Doherty, R; Ellis, IO; Green, AR; Madhusudan, S; Martin, SG; Middleton, F; Moseley, PM; Rakha, EA; Stephens, P | 1 |
| Donnelly, L; Elghobashi-Meinhardt, N; Li, X; Liu, Y; Long, T; Qi, X; Sun, Y; Wang, B; Zhou, RW | 1 |
1 trial(s) available for pyrazines and serine
| Article | Year |
|---|---|
A phase II trial with pharmacodynamic endpoints of the proteasome inhibitor bortezomib in patients with metastatic colorectal cancer.
Topics: Aged; Aged, 80 and over; Antigens, Neoplasm; Antineoplastic Agents; Biopsy; Boronic Acids; Bortezomib; Carbonic Anhydrase IX; Carbonic Anhydrases; Colorectal Neoplasms; Disease Progression; Enzyme Inhibitors; Female; Humans; Immunohistochemistry; Infusions, Intravenous; Liver; Male; Microcirculation; Middle Aged; Neoplasm Metastasis; Neoplasm Transplantation; NF-kappa B; Phosphorylation; Proteasome Inhibitors; Pyrazines; Serine; Time Factors; Treatment Outcome; Tumor Suppressor Protein p53 | 2005 |
14 other study(ies) available for pyrazines and serine
| Article | Year |
|---|---|
Binding proteins for linear renin-inhibiting peptides in basolateral plasma membranes of rat liver.
Topics: Animals; Biological Transport; Cell Membrane; Cholic Acids; Chromatography, Affinity; Dipeptides; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Male; Molecular Structure; Oleic Acids; Oligopeptides; Protein Binding; Pyrazines; Pyrimidines; Rats; Rats, Inbred Strains; Renin; Serine; Solubility; Taurocholic Acid; Thiamine | 1992 |
Pyrazine formation from serine and threonine.
Topics: Flame Ionization; Food Preservation; Gas Chromatography-Mass Spectrometry; Hot Temperature; Humans; Pyrazines; Serine; Threonine | 1999 |
Phosphorylation of AML1/RUNX1 regulates its degradation and nuclear matrix association.
Topics: Animals; Boronic Acids; Bortezomib; Core Binding Factor Alpha 2 Subunit; DNA-Binding Proteins; Immunoprecipitation; Mice; Mice, Knockout; Mutation; Nuclear Matrix; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins; Pyrazines; Serine; Threonine; Transcription Factors; Transcription, Genetic; Ubiquitin | 2005 |
Role of p90 ribosomal S6-kinase-1 in oltipraz-induced specific phosphorylation of CCAAT/enhancer binding protein-beta for GSTA2 gene transactivation.
Topics: Amino Acid Sequence; Animals; CCAAT-Enhancer-Binding Protein-beta; Cell Line; Chromatin Immunoprecipitation; Glutathione Transferase; Humans; Isoenzymes; Mice; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphorylation; Pyrazines; Rats; Ribosomal Protein S6 Kinases, 90-kDa; RNA, Small Interfering; Sequence Homology, Amino Acid; Serine; Thiones; Thiophenes; Transcriptional Activation; Transfection | 2006 |
Dual alterations in casein kinase I-epsilon and GSK-3beta modulate beta-catenin stability in hyperproliferating colonic epithelia.
Topics: Animals; Axin Protein; beta Catenin; Boronic Acids; Bortezomib; Casein Kinase 1 epsilon; Cell Nucleus; Citrobacter rodentium; Colon; Cyclic AMP Response Element-Binding Protein; Cytoskeleton; DNA; Enterobacteriaceae Infections; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperplasia; Immunoprecipitation; Intestinal Mucosa; Mice; Phosphorylation; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Binding; Protein Kinase C; Pyrazines; Repressor Proteins; Serine; TCF Transcription Factors; Threonine; Transcription Factor 7-Like 2 Protein | 2007 |
Formation of pyrazines in Maillard model systems of lysine-containing dipeptides.
Topics: Cystine; Dipeptides; Food Analysis; Gas Chromatography-Mass Spectrometry; Glucose; Leucine; Lysine; Maillard Reaction; Peptides; Phenylalanine; Pyrazines; Serine | 2010 |
Protective effect of ligustrazine against myocardial ischaemia reperfusion in rats: the role of endothelial nitric oxide synthase.
Topics: Animals; Apoptosis; Cardiotonic Agents; Caspase 3; Enzyme Inhibitors; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction | 2012 |
Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation.
Topics: Analysis of Variance; Animals; Boronic Acids; Bortezomib; Cells, Cultured; Dendrites; Disks Large Homolog 4 Protein; Drosophila Proteins; Embryo, Mammalian; Enzyme Inhibitors; Female; Fragile X Mental Retardation Protein; Gene Expression Regulation; Green Fluorescent Proteins; Hippocampus; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Leupeptins; Male; Membrane Proteins; Methoxyhydroxyphenylglycol; Mutation; Neurons; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Protein Biosynthesis; Pyrazines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; RNA, Messenger; Serine; Signal Transduction; Synapses; Transfection; Ubiquitination | 2012 |
A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site.
Topics: Adamantane; Catalytic Domain; Crystallography, X-Ray; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Humans; Multiprotein Complexes; Nitriles; Oligopeptides; Piperidines; Protein Binding; Protein Interaction Mapping; Pyrazines; Pyrazoles; Pyrrolidines; Serine; Sitagliptin Phosphate; Structure-Activity Relationship; Thiazolidines; Triazoles; Uracil; Vildagliptin; X-Ray Diffraction | 2013 |
The checkpoint 1 kinase inhibitor LY2603618 induces cell cycle arrest, DNA damage response and autophagy in cancer cells.
Topics: Antineoplastic Agents; Antirheumatic Agents; Autophagy; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Checkpoint Kinase 1; Chloroquine; DNA Damage; DNA Repair; G2 Phase Cell Cycle Checkpoints; Humans; Lung Neoplasms; MAP Kinase Kinase 4; Nuclear Proteins; p38 Mitogen-Activated Protein Kinases; Phenylurea Compounds; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Pyrazines; Serine | 2014 |
Activation of AMPKα2 in adipocytes is essential for nicotine-induced insulin resistance in vivo.
Topics: Adipocytes; Adiposity; AMP-Activated Protein Kinases; Animals; Body Composition; Body Weight; Dual Specificity Phosphatase 1; Enzyme Activation; HEK293 Cells; Homeostasis; Humans; Hypolipidemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Phosphorylation; Pyrazines; Rats; Serine; Smoking | 2015 |
Two-step one-pot synthesis of dihydropyrazinones as Xaa-Ser dipeptide isosteres through morpholine acetal rearrangement.
Topics: Acetals; Acylation; Crystallography, X-Ray; Dipeptides; Models, Molecular; Morpholines; Pyrazines; Pyridines; Serine | 2015 |
Chk1 phosphorylated at serine345 is a predictor of early local recurrence and radio-resistance in breast cancer.
Topics: Ataxia Telangiectasia Mutated Proteins; Breast Neoplasms; Checkpoint Kinase 1; Cohort Studies; DNA Repair; DNA-Binding Proteins; Female; Gene Knockdown Techniques; Humans; Indoles; MCF-7 Cells; Neoplasm Recurrence, Local; Neoplasm Staging; Phosphorylation; Protein Kinases; Pyrazines; Pyridones; Radiation Tolerance; RNA Interference; RNA, Small Interfering; Serine; Sulfones; Up-Regulation | 2016 |
Mechanisms and inhibition of Porcupine-mediated Wnt acylation.
Topics: Acylation; Acyltransferases; Antineoplastic Agents; Binding Sites; Coenzyme A; Cryoelectron Microscopy; Histidine; Humans; Membrane Proteins; Neoplasms; Palmitoyl Coenzyme A; Pyrazines; Pyridines; Serine; Substrate Specificity; Wnt Signaling Pathway; Wnt3A Protein | 2022 |