Page last updated: 2024-08-21

pyrazines and sch 1473759

pyrazines has been researched along with sch 1473759 in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Basso, AD; Esposite, S; Gray, K; Hicklin, DJ; Kerekes, AD; Kirschmeier, P; Lee, S; Liang, L; Liu, M; Monsma, FJ; Ponery, A; Smith, EB; Tagat, JR; Tevar, S; Xiao, Y; Yu, T; Zhang, Y	1
Ferraz Nogueira Filho, MA; Figg, WD; Helman, L; McCalla, A; Nguyen, J; Peer, CJ	1

Other Studies

2 other study(ies) available for pyrazines and sch 1473759

Article	Year
SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors. Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:4 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Aurora Kinases; Cell Line, Tumor; Drug Administration Schedule; Female; Humans; Imidazoles; Kinesins; Male; Mice; Mice, Nude; Neoplasms; Protein Serine-Threonine Kinases; Pyrazines; Taxoids; Xenograft Model Antitumor Assays	2011
A simple and rapid UHPLC-MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma. Journal of pharmaceutical and biomedical analysis, 2017, Jan-05, Volume: 132 Topics: Administration, Oral; Animals; Aurora Kinase A; Aurora Kinase B; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Half-Life; Imidazoles; Linear Models; Liquid-Liquid Extraction; Mice; Plasma; Pyrazines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry	2017

Article

Year

SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors.

Cancer chemotherapy and pharmacology, 2011, Volume: 68, Issue:4

Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aurora Kinase A; Aurora Kinases; Cell Line, Tumor; Drug Administration Schedule; Female; Humans; Imidazoles; Kinesins; Male; Mice; Mice, Nude; Neoplasms; Protein Serine-Threonine Kinases; Pyrazines; Taxoids; Xenograft Model Antitumor Assays

2011

A simple and rapid UHPLC-MS/MS method for the quantitation of the dual aurora kinase A/B inhibitor SCH-1473759 in murine plasma.

Journal of pharmaceutical and biomedical analysis, 2017, Jan-05, Volume: 132

Topics: Administration, Oral; Animals; Aurora Kinase A; Aurora Kinase B; Biological Availability; Chromatography, High Pressure Liquid; Drug Stability; Half-Life; Imidazoles; Linear Models; Liquid-Liquid Extraction; Mice; Plasma; Pyrazines; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry

2017