Compounds > pyrazines
Page last updated: 2024-08-21

pyrazines and sar 020106

pyrazines has been researched along with sar 020106 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aherne, GW; Box, G; Boxall, KJ; Collins, I; De Haven Brandon, A; Eccles, SA; Eve, PD; Garrett, MD; Hayes, A; Raynaud, FI; Reader, JC; Valenti, M; Walton, MI; Williams, DH1
Borst, GR; Collins, I; Garrett, MD; Good, J; Harrington, KJ; Khan, A; Kyula, JN; McLaughlin, M; Meier, P; Neijenhuis, S; Powell, NG; Verheij, M; Zaidi, S1
Borst, G; Clayton, J; Collins, I; Federspiel, MJ; Garrett, M; Harrington, KJ; Karapanagiotou, EM; Khan, AA; Kyula, J; Mansfield, D; McLaughlin, M; Pencavel, T; Roulstone, V; Russell, SJ; Touchefeu, Y; Zaidi, SH1

Other Studies

3 other study(ies) available for pyrazines and sar 020106

ArticleYear
The preclinical pharmacology and therapeutic activity of the novel CHK1 inhibitor SAR-020106.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Camptothecin; Cell Death; Cell Line, Tumor; Checkpoint Kinase 1; Deoxycytidine; DNA Damage; Drug Synergism; G2 Phase; Gemcitabine; Humans; Irinotecan; Isoquinolines; Mice; Mice, Nude; Mutagens; Phosphorylation; Protein Kinase Inhibitors; Protein Kinases; Pyrazines; Xenograft Model Antitumor Assays

2010
Targeted radiosensitization by the Chk1 inhibitor SAR-020106.
    International journal of radiation oncology, biology, physics, 2013, Mar-15, Volume: 85, Issue:4

    Topics: Animals; Apoptosis; Cell Cycle; Cell Line, Tumor; Checkpoint Kinase 1; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; DNA Repair; G2 Phase; HeLa Cells; Histones; Humans; Immunohistochemistry; Isoquinolines; Mice; Mice, Nude; Microscopy; Mitosis; Papillomaviridae; Protein Kinases; Pyrazines; Radiation Tolerance; Radiation-Sensitizing Agents; Time-Lapse Imaging; Tumor Stem Cell Assay; Tumor Suppressor Protein p53

2013
Optimising measles virus-guided radiovirotherapy with external beam radiotherapy and specific checkpoint kinase 1 inhibition.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:1

    Topics: Animals; Cell Line, Tumor; Checkpoint Kinase 1; Colorectal Neoplasms; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Iodine Radioisotopes; Isoquinolines; Measles virus; Mice; Oncolytic Virotherapy; Protein Kinase Inhibitors; Protein Kinases; Pyrazines; Radiation-Sensitizing Agents; Symporters; Virus Replication; Xenograft Model Antitumor Assays

2013