Page last updated: 2024-08-21

pyrazines and pyrazolo(1,5-a)pyrimidine

pyrazines has been researched along with pyrazolo(1,5-a)pyrimidine in 1 studies

Research

Studies (1)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	1 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ashizawa, T; Hoffman, ID; Imada, H; Iwashita, H; Kamiguchi, N; Kawasaki, M; Kokubo, H; Mikami, S; Nakamura, S; Nakashima, K; Nomura, I; Oki, H; Sasaki, S; Suzuki, N; Taniguchi, T; Uchiyama, N; Zou, H	1

Other Studies

1 other study(ies) available for pyrazines and pyrazolo(1,5-a)pyrimidine

Article	Year
Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor Journal of medicinal chemistry, 2017, 09-28, Volume: 60, Issue:18 Topics: Animals; Brain; Cognition; Cognition Disorders; Crystallography, X-Ray; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Drug Design; Halogenation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Phosphodiesterase Inhibitors; Pyrazines; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley	2017

Article

Year

Discovery of Clinical Candidate N-((1S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-2-methoxyethyl)-7-methoxy-2-oxo-2,3-dihydropyrido[2,3-b]pyrazine-4(1H)-carboxamide (TAK-915): A Highly Potent, Selective, and Brain-Penetrating Phosphodiesterase 2A Inhibitor

Journal of medicinal chemistry, 2017, 09-28, Volume: 60, Issue:18

Topics: Animals; Brain; Cognition; Cognition Disorders; Crystallography, X-Ray; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Drug Design; Halogenation; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Phosphodiesterase Inhibitors; Pyrazines; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley

2017