Page last updated: 2024-08-21

pyrazines and pyrazinamide

pyrazines has been researched along with pyrazinamide in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199029 (56.86)18.7374
1990's6 (11.76)18.2507
2000's9 (17.65)29.6817
2010's6 (11.76)24.3611
2020's1 (1.96)2.80

Authors

AuthorsStudies
Cadenhead, A; Cameron, JS; Hatfield, PJ; Simmonds, HA1
Bohn, DL; Fanelli, GM; Zacchei, AG1
Roboz, J; Suzuki, R; Yü, TF1
Bravo, TC; Ellard, GA; Mitchison, DA1
Foks, H; Manowska, W; Sienicka, J1
Ellard, GA; Haslam, RM1
Beyer, KH; Gelarden, RT; Jeszenka, EV; Passananti, GT; Vesell, ES1
Erdos, G; Gonzalez-Rothi, RJ; Guo, XD; Liu, ZZ; Prankerd, RJ; Schreier, H; Straub, LE1
Kobayashi, M; Nagasawa, T; Yamada, H; Yanaka, N1
Wayne, LG1
Dulin, WE; Wyse, BM1
Lucchesi, M; Mancini, P; Matzeu, M1
Singer, MA1
Fanelli, GM; Weiner, IM1
Tinker, JP; Weiner, IM1
Toida, I1
Pavlov, EP; Soloviev, VN1
Zierski, M3
Calò, A; Cardini, C; Quercia, V1
Gialdronigrassi, G; Grassi, C1
Gajewska, E; Zierski, M1
Lachowicz, D; Siekierzyńska, A; Styszewska, H1
Stastná, J; Tousek, J; Viklický, J; Zítková, L1
Imai, H; Nasu, S; Sakakibara, S; Ueda, I; Yamaguchi, K1
A-Rahim, YI; Beyer, KH; Vesell, ES1
Beyer, KH; Vesell, ES1
Heifets, L; Higgins, M; Simon, B1
Bohme, GA; Boireau, A; Bouquerel, J; Damour, D; Debono, MW; Genevois-Borella, A; Hardy, JC; Hubert, P; Jimonet, P; Manfré, F; Mignani, S; Nemecek, P; Pratt, J; Randle, JC; Ribeill, Y; Stutzmann, JM; Vuilhorgne, M1
Teyssier, L1
Abrigo, C; Calvino, R; Gennaro, MC1
Reynolds, RC; Seitz, LE; Suling, WJ1
CALABRESE, L; MIGLIOLI, S1
DUSI, U; GRECO, S; MENOZZI, V1
BOENICKE, R; FREERKSEN, E; ROSENFELD, M1
FELDER, E; TIEPOLO, U1
FOKS, H; SAWLEWICZ, J1
BISETTI, A; CORATO, P; FORTUNI, M; LOSCHI, GC; MARIANI, B; SALOMONE, G1
Foks, H; Janowiec, M; Orlewska, C1
Berkers, CR; Groll, M; Ovaa, H; Ploegh, HL1
Buchta, V; Dolezal, M; Dvorák, J; Jampílek, J; Palek, L; Svobodová, M1
Gyepes, R; Pacigová, S; Sivák, M; Tatiersky, J1
Dolezal, M; Kesetovicová, D; Kunes, J; Svobodová, M; Zitko, J1
Cole, EL; Desmond, TJ; Fawaz, MV; Quesada, C; Scott, PJ; Shao, X; Sherman, P1
Charushin, VN; Chupakhin, ON; Evstigneeva, NP; Kravchenko, MA; Kungurov, NV; Rusinov, GL; Skornyakov, SN; Slepukhin, PA; Verbitskiy, EV; Zil'berberg, NV1
Dolezal, M; Konecna, K; Kralova, K; Kubicek, V; Kunes, J; Marek, J; Naesens, L; Novakova, L; Paterova, P; Pesko, M; Semelkova, L; Zitko, J1
Gonnade, RG; Sahu, SK; Thorat, SH1
Dolezal, M; Holas, O; Jandourek, O; Konecna, K; Kubicek, V; Navratilova, L; Paterova, P; Tauchman, M; Zitko, J1
Bakuradze, T; Buckel, L; Eisenbrand, G; Glaß-Theis, A; Kremer, JI; Pickard, S; Richling, E; Stadlmair, LF1
Achanta, PS; Chen, SN; Pauli, GF1

Trials

2 trial(s) available for pyrazines and pyrazinamide

ArticleYear
[Comparison between morphazinamide and pyrazinamide in retreatment of pulmonary tuberculosis].
    Minerva medica, 1965, Sep-05, Volume: 56, Issue:71

    Topics: Antitubercular Agents; Clinical Trials as Topic; Humans; Pyrazinamide; Pyrazines; Tuberculosis, Pulmonary

1965
Studies on pyrazinoylguanidine. 7. Effects of single oral doses in normal human subjects.
    Pharmacology, 1999, Volume: 58, Issue:3

    Topics: Adult; Blood Glucose; Cross-Over Studies; Fatty Acids, Nonesterified; Guanidines; Hormones; Humans; Hypolipidemic Agents; Lipids; Male; Pyrazinamide; Pyrazines; Single-Blind Method

1999

Other Studies

49 other study(ies) available for pyrazines and pyrazinamide

ArticleYear
Uric acid excretion by the pig kidney.
    The American journal of physiology, 1976, Volume: 230, Issue:6

    Topics: Animals; Blood Proteins; Diuresis; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Kidney; Male; Probenecid; Pyrazinamide; Pyrazines; Swine; Uric Acid; Urine

1976
Renal excretion of a slauretic-uricosuric agent (MK-196) and interaction with a urate-retaining drug, pyrazinoate, in the chimpanzee.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 200, Issue:2

    Topics: Acetazolamide; Animals; Diuresis; Drug Interactions; Glomerular Filtration Rate; Hydrogen-Ion Concentration; Indans; Indenes; Kidney; Male; p-Aminohippuric Acid; Pan troglodytes; Probenecid; Pyrazinamide; Pyrazines; Sodium Chloride; Time Factors; Uric Acid; Uricosuric Agents

1977
Mass fragmentographic determination of pyrazinamide and its metabolites in serum and urine.
    Journal of chromatography, 1978, Jan-11, Volume: 147

    Topics: Gas Chromatography-Mass Spectrometry; Humans; Methods; Pyrazinamide; Pyrazines

1978
Reappraisal of the activity of morphazinamide against M. tuberculosis.
    Tubercle, 1975, Volume: 56, Issue:3

    Topics: Animals; Female; Formaldehyde; Humans; Hydrolysis; Mice; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines; Time Factors; Tuberculosis, Pulmonary

1975
[Synthesis and tuberculostatic activity of some derivatives of pyrazine-2-carboxylic acid].
    Acta poloniae pharmaceutica, 1976, Volume: 33, Issue:6

    Topics: Antitubercular Agents; Chemical Phenomena; Chemistry; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines

1976
Observations on the reduction of the renal elimination of urate in man caused by the administration of pyrazinamide.
    Tubercle, 1976, Volume: 57, Issue:2

    Topics: Humans; Male; Pyrazinamide; Pyrazines; Time Factors; Uric Acid

1976
Pharmacokinetics of pyrazinoyl-guanidine, 3-aminopyrazinoyl-guanidine and their corresponding pyrazinoic acid metabolites in humans and dogs.
    Pharmacology, 1992, Volume: 45, Issue:3

    Topics: Animals; Chromatography, High Pressure Liquid; Dogs; Dose-Response Relationship, Drug; Drug Stability; Guanidines; Half-Life; Humans; Hydrolysis; Molecular Structure; Pyrazinamide; Pyrazines; Uremia

1992
Lipophilic N-acylpyrazinamide derivatives: synthesis, physicochemical characterization, liposome incorporation, and in vitro activity against Mycobacterium avium-intracellulare.
    Drug design and discovery, 1991, Volume: 8, Issue:1

    Topics: Acetylation; Anti-Bacterial Agents; Antitubercular Agents; Chemical Phenomena; Chemistry, Physical; Humans; Liposomes; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Pyrazinamide; Pyrazines

1991
Nitrilase-catalyzed production of pyrazinoic acid, an antimycobacterial agent, from cyanopyrazine by resting cells of Rhodococcus rhodochrous J1.
    The Journal of antibiotics, 1990, Volume: 43, Issue:10

    Topics: Aminohydrolases; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Mass Spectrometry; Pyrazinamide; Pyrazines; Rhodococcus; Spectrophotometry, Infrared; Temperature

1990
Simple pyrazinamidase and urease tests for routine identification of mycobacteria.
    The American review of respiratory disease, 1974, Volume: 109, Issue:1

    Topics: Amidohydrolases; Bacteriological Techniques; Carboxylic Acids; Culture Media; Mycobacterium; Mycobacterium bovis; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines; Spectrophotometry; Urease

1974
Studies on the ability of compounds to block the diabetogenic activity of streptozotocin.
    Diabetes, 1969, Volume: 18, Issue:7

    Topics: Amino Acids; Animals; Diabetes Mellitus; Diaphragm; Diazoxide; Epinephrine; Ethanol; Glucosamine; Glucose; Hyperglycemia; Hypoglycemic Agents; Male; NAD; Niacinamide; Nitroso Compounds; Pyrazinamide; Pyrazines; Pyrazoles; Rats; Tolbutamide

1969
[Drug sensitivity of the so-called atypical mycobacteria].
    Annali dell'Istituto "Carlo Forlanini", 1968, Volume: 28, Issue:1

    Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; In Vitro Techniques; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Morpholines; Mycobacterium; Pyrazinamide; Pyrazines; Rifampin; Streptomycin; Viomycin

1968
Effects of amiloride and dibucaine on a model phospholipid membrane--structure-activity relationships.
    Biochemical pharmacology, 1974, Nov-01, Volume: 23, Issue:21

    Topics: Amiloride; Calcium; Chemical Phenomena; Chemistry; Cholesterol; Dibucaine; Diuretics; Eggs; Electrophoresis; Guanidines; Kinetics; Liposomes; Membranes, Artificial; Models, Chemical; Permeability; Phosphatidylcholines; Phospholipids; Pyrazinamide; Pyrazines; Radioisotopes; Sodium Isotopes; Structure-Activity Relationship; Surface Properties

1974
Bidirectional renal urate transport in the chimpanzee. Effects of drugs on secretory and reabsorptive fluxes.
    Progress in biochemical pharmacology, 1974, Volume: 9

    Topics: Aminohippuric Acids; Animals; Biological Transport; Glomerular Filtration Rate; Kidney Tubules; Kidney Tubules, Distal; Male; Mersalyl; Pan troglodytes; Probenecid; Pyrazinamide; Pyrazines; Salicylates; Uric Acid; Uricosuric Agents

1974
Pharmacology of pyrazinamide: metabolic and renal function studies related to the mechanism of drug-induced urate retention.
    The Journal of pharmacology and experimental therapeutics, 1972, Volume: 180, Issue:2

    Topics: Adsorption; Allopurinol; Animals; Biological Transport, Active; Biotransformation; Carboxylic Acids; Colorimetry; Dogs; Female; Filtration; Haplorhini; Humans; Inulin; Kidney; Kidney Function Tests; Kidney Tubules; Male; Metabolism; Pyrazinamide; Pyrazines; Uric Acid; Uricosuric Agents

1972
Metabolism of pyrazinamide. Pyrazinamide deamidase of animal tissues.
    The American review of respiratory disease, 1973, Volume: 107, Issue:4

    Topics: Amidohydrolases; Animals; Carboxylic Acids; Female; Guinea Pigs; Hydrogen-Ion Concentration; Kidney; Liver; Lung; Mice; Mice, Inbred Strains; Pyrazinamide; Pyrazines; Rabbits; Rats; Time Factors

1973
Significance of intracellular medium for antimycobacterial activity of some pyrazin-2-carbonic acid derivatives.
    Chemotherapy, 1966, Volume: 11, Issue:6

    Topics: Animals; Antitubercular Agents; Culture Media; Culture Techniques; Hydrogen-Ion Concentration; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines

1966
[Use of gas chromatography in pharmaceutical analysis. X. Further studies on antitubercular drugs].
    Bollettino chimico farmaceutico, 1969, Volume: 108, Issue:3

    Topics: Antitubercular Agents; Chromatography, Gas; Ethionamide; Morpholines; Pyrazinamide; Pyrazines

1969
[Metabolism of morphazinamide in patients with pulmonary tuberculosis].
    Minerva medica, 1965, Sep-01, Volume: 56, Issue:70

    Topics: Antitubercular Agents; Humans; Pyrazinamide; Pyrazines; Tuberculosis, Pulmonary

1965
[Research on metabolic degradation of morphazinamide].
    Minerva medica, 1965, Sep-01, Volume: 56, Issue:70

    Topics: Animals; Antitubercular Agents; Chromatography; Humans; In Vitro Techniques; Pyrazinamide; Pyrazines; Rats; Urine

1965
[Comparison of the effect of morphazinamide and pyrazinamide in the treatment of chronic tuberculosis].
    Gruzlica i choroby pluc; tuberculosis et pneumonologia, 1965, Volume: 33, Issue:9

    Topics: Antitubercular Agents; Humans; Pyrazinamide; Pyrazines; Tuberculosis, Pulmonary

1965
[On the metabolism of morphazinamide in the treatment of chronic pulmonary tuberculosis].
    Gruzlica i choroby pluc; tuberculosis et pneumonologia, 1965, Volume: 33, Issue:9

    Topics: Blood Proteins; Humans; Pyrazinamide; Pyrazines; Tuberculosis, Pulmonary

1965
[Morphazinamide--clinical tolerance and side effects].
    Gruzlica i choroby pluc; tuberculosis et pneumonologia, 1967, Volume: 35, Issue:5

    Topics: Adolescent; Adult; Aged; Antitubercular Agents; Ethionamide; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Pyrazinamide; Pyrazines; Tuberculosis, Pulmonary

1967
Toxicity of morphazinamide compared with pyrazinamide.
    Czechoslovak medicine, 1983, Volume: 6, Issue:3

    Topics: Animals; Blood Chemical Analysis; Body Weight; Eating; Liver; Male; Pyrazinamide; Pyrazines; Rats; Rats, Inbred Strains

1983
The effect of pyrazines on the metabolism of tryptophan and nicotinamide adenine dinucleotide in the rat. Evidence of the formation of a potent inhibitor of aminocarboxy-muconate-semialdehyde decarboxylase from pyrazinamide.
    Biochimica et biophysica acta, 1981, Sep-18, Volume: 677, Issue:1

    Topics: Animals; Carboxy-Lyases; Kidney; Liver; Male; NAD; Nicotinic Acids; Poly(ADP-ribose) Polymerases; Pyrazinamide; Pyrazines; Rats; Rats, Inbred Strains; Tryptophan

1981
Studies on pyrazinoylguanidine. 2. Comparative drug and dose effects on glucose and lipid metabolism in streptozotocin-induced diabetic rats.
    Pharmacology, 1996, Volume: 52, Issue:3

    Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glyburide; Guanidines; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Metabolism; Male; Metformin; Pyrazinamide; Pyrazines; Rats; Rats, Sprague-Dawley; Streptozocin

1996
Pyrazinamide is not active against Mycobacterium tuberculosis residing in cultured human monocyte-derived macrophages.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2000, Volume: 4, Issue:6

    Topics: Antitubercular Agents; Cells, Cultured; Humans; Isoniazid; Macrophages; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines

2000
Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action.
    Bioorganic & medicinal chemistry letters, 2001, Jan-22, Volume: 11, Issue:2

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Combinatorial Chemistry Techniques; Disease Models, Animal; Excitatory Amino Acid Antagonists; Imidazoles; Inhibitory Concentration 50; Male; Mice; Oocytes; Pyrazinamide; Pyrazines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship

2001
Higher activity of morphazinamide over pyrazinamide against intracellular.
    The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2001, Volume: 5, Issue:4

    Topics: Antitubercular Agents; Humans; Isoniazid; Macrophages; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines; Sensitivity and Specificity

2001
Ion interaction reagent reversed-phase high-performance liquid chromatography determination of anti-tuberculosis drugs and metabolites in biological fluids.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, Apr-25, Volume: 754, Issue:2

    Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Calibration; Chromatography, High Pressure Liquid; Ethionamide; Humans; Isoniazid; Isonicotinic Acids; Niacin; Pyrazinamide; Pyrazines; Quality Control; Rats

2001
Synthesis and antimycobacterial activity of pyrazine and quinoxaline derivatives.
    Journal of medicinal chemistry, 2002, Dec-05, Volume: 45, Issue:25

    Topics: Anti-Bacterial Agents; Microbial Sensitivity Tests; Mycobacterium avium; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines; Quinoxalines; Structure-Activity Relationship

2002
[THE THERAPY OF PULMONARY TUBERCULOSIS WITH MORPHAZINAMIDE. CLINICAL CONTRIBUTION].
    La Clinica terapeutica, 1963, Aug-31, Volume: 26

    Topics: Antitubercular Agents; Humans; Pyrazinamide; Pyrazines; Tuberculosis; Tuberculosis, Pulmonary

1963
[PRELIMINARY FUNCTIONAL AND MORPHOLOGICAL HEPATIC FINDINGS IN PATIENTS TREATED WITH MORPHAZINAMIDE].
    Rivista di anatomia patologica e di oncologia, 1963, Volume: 23

    Topics: Antitubercular Agents; Fatty Liver; Humans; Liver Function Tests; Pyrazinamide; Pyrazines; Silicotuberculosis; Toxicology; Tuberculosis; Tuberculosis, Pulmonary

1963
[COMPARATIVE STUDIES ON THE TUBERCULOSTATIC ACTIVITY OF N-MORPHOLINOMETHYLPYRAZINAMIDE AND PYRAZINE-2-CARBOXAMIDE (PYRAZINAMIDE) IN VITRO AND IN VIVO].
    Arzneimittel-Forschung, 1963, Volume: 13

    Topics: Animals; Antitubercular Agents; In Vitro Techniques; Mice; Morpholines; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines; Research

1963
[PYRAZINE CARBOXYLIC ACID AMINOMETHYLAMIDES. 1. ON THE LATENT FORMS OF CHEMOTHERAPEUTICALLY ACTIVE PRINCIPLES].
    Arzneimittel-Forschung, 1964, Volume: 14

    Topics: Carboxylic Acids; Chemistry, Pharmaceutical; Formaldehyde; Pharmacology; Pyrazinamide; Pyrazines; Research

1964
[N-OXIDES OF 2-PYRAZINECARBOXYLIC ACID].
    Acta poloniae pharmaceutica, 1964, Volume: 21

    Topics: Chemistry, Pharmaceutical; Oxides; Pyrazinamide; Pyrazines; Research

1964
[On the therapeutic and side effects of morfazinamide in the treatment of tuberculosis].
    Minerva medica, 1962, Jun-02, Volume: 53

    Topics: Humans; Pyrazinamide; Pyrazines; Tuberculosis

1962
[Study of the synthesis of pyrazine derivates. Part XXVIII. Reaction of pyrazineamide with CS-2].
    Acta poloniae pharmaceutica, 1992, Volume: 49, Issue:5-6

    Topics: Azo Compounds; Chemistry, Pharmaceutical; Pyrazinamide; Pyrazines; Thiadiazoles; Triazoles

1992
Crystal structure of the boronic acid-based proteasome inhibitor bortezomib in complex with the yeast 20S proteasome.
    Structure (London, England : 1993), 2006, Volume: 14, Issue:3

    Topics: Animals; Antineoplastic Agents; Boronic Acids; Bortezomib; Catalytic Domain; Crystallization; Leucine; Mammals; Models, Molecular; Peptides; Phenylalanine; Proteasome Endopeptidase Complex; Protein Structure, Quaternary; Pyrazinamide; Pyrazines; Structure-Activity Relationship; Substrate Specificity; Yeasts

2006
Synthesis, antimycobacterial and antifungal evaluation of 3-arylaminopyrazine-2,5-dicarbonitriles.
    Archiv der Pharmazie, 2008, Volume: 341, Issue:1

    Topics: Absidia; Antifungal Agents; Antitubercular Agents; Aspergillus fumigatus; Candida; Chromatography, High Pressure Liquid; Microbial Sensitivity Tests; Mycobacterium; Nitriles; Pyrazinamide; Pyrazines; Structure-Activity Relationship; Trichosporon

2008
Interpretation of the multiple vanadium-oxygen bonds in the central VO(eta2-O2)+ group. Synthesis, structure, supramolecular interactions and DFT studies for complexes with 2,2'-bipyridine, 1,10-phenanthroline, pyrazinato(1-) and pyrazinamide ligands.
    Dalton transactions (Cambridge, England : 2003), 2008, Jan-07, Issue:1

    Topics: 2,2'-Dipyridyl; Crystallography, X-Ray; Hydrogen Bonding; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Organometallic Compounds; Phenanthrolines; Pyrazinamide; Pyrazines; Thermodynamics; Vanadates

2008
Substituted N-Phenylpyrazine-2-carboxamides: synthesis and antimycobacterial evaluation.
    Molecules (Basel, Switzerland), 2009, Oct-20, Volume: 14, Issue:10

    Topics: Antitubercular Agents; Mycobacterium avium; Mycobacterium kansasii; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines

2009
Synthesis and evaluation of [(11)C]PyrATP-1, a novel radiotracer for PET imaging of glycogen synthase kinase-3β (GSK-3β).
    Nuclear medicine and biology, 2014, Volume: 41, Issue:6

    Topics: Animals; Brain; Carbon Radioisotopes; Chemistry Techniques, Synthetic; Female; Glycogen Synthase Kinase 3; Positron-Emission Tomography; Protein Kinase Inhibitors; Pyrazinamide; Pyrazines; Radioactive Tracers; Radiochemistry; Rats; Sulfonamides

2014
Synthesis, antimycobacterial and antifungal evaluation of some new 1-ethyl-5-(hetero)aryl-6-styryl-1,6-dihydropyrazine-2,3-dicarbonitriles.
    Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3

    Topics: Antifungal Agents; Antitubercular Agents; Crystallography, X-Ray; Drug Resistance, Bacterial; Fungi; Microbial Sensitivity Tests; Molecular Conformation; Mycobacterium tuberculosis; Nitriles; Oxidation-Reduction; Pyrazinamide; Pyrazines; Silanes; Stereoisomerism; Structure-Activity Relationship

2015
Synthesis and Biological Evaluation of N-Alkyl-3-(alkylamino)-pyrazine-2-carboxamides.
    Molecules (Basel, Switzerland), 2015, May-14, Volume: 20, Issue:5

    Topics: Antitubercular Agents; Bacterial Proteins; Chloroplasts; Electron Transport; Fatty Acid Synthases; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines; Spinacia oleracea; Structure-Activity Relationship

2015
Crystal structures of the pyrazinamide-p-aminobenzoic acid (1/1) cocrystal and the transamidation reaction product 4-(pyrazine-2-carboxamido)benzoic acid in the molten state.
    Acta crystallographica. Section C, Structural chemistry, 2015, Volume: 71, Issue:Pt 11

    Topics: Aminobenzoates; Antitubercular Agents; Benzoates; Benzoic Acid; Crystallography, X-Ray; Hydrogen Bonding; Models, Molecular; Pyrazinamide; Pyrazines

2015
Synthesis of Novel Pyrazinamide Derivatives Based on 3-Chloropyrazine-2-carboxamide and Their Antimicrobial Evaluation.
    Molecules (Basel, Switzerland), 2017, Feb-02, Volume: 22, Issue:2

    Topics: Amides; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitubercular Agents; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Pyrazinamide; Pyrazines; Structure-Activity Relationship

2017
Alkylpyrazines from Coffee are Extensively Metabolized to Pyrazine Carboxylic Acids in the Human Body.
    Molecular nutrition & food research, 2019, Volume: 63, Issue:14

    Topics: Adult; Carboxylic Acids; Chromatography, High Pressure Liquid; Coffee; Female; Healthy Volunteers; Humans; Male; Pyrazinamide; Pyrazines; Spectrometry, Mass, Electrospray Ionization

2019
Plain
    Magnetic resonance in chemistry : MRC, 2021, Volume: 59, Issue:7

    Topics: Amides; Antiviral Agents; Drug Contamination; Niacinamide; Proton Magnetic Resonance Spectroscopy; Pyrazinamide; Pyrazines; Quality Control; World Health Organization

2021