Compounds > pyrazines
Page last updated: 2024-08-21

pyrazines and pteridines

pyrazines has been researched along with pteridines in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199011 (61.11)18.7374
1990's0 (0.00)18.2507
2000's1 (5.56)29.6817
2010's5 (27.78)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Bonner, JT; Hall, EM; Pan, P1
Kubo, S; Takamatsu, Y; Tanabe, T; Uesaka, I; Yamada, K1
Furumoto, S; Mitsuda, H; Suzuki, Y1
Haddow, A; Ross, WC; Timmis, GM1
Hieda, M; Yurugi, S1
Albert, A; Ota, K1
Beach, RL; Plaut, GW1
Brade, W; Propping, P1
Cragoe, EJ; Jones, JH1
Bicking, JB; Cragoe, EJ; Jones, JH1
Dneprovskaia, E; Doukas, J; Fine, RM; Hood, J; Kang, X; Lohse, D; Martin, M; Noronha, G; Palanki, MS; Soll, RM; Wrasidlo, W; Yee, S; Zhu, H1
CAIN, CK; MALLETTE, MF; TAYLOR, EC1
Feng, Y; Lee, J; Liu, ZJ; Titushin, MS; Vysotski, ES1
Elemento, O; Houghtaling, BR; Kapoor, TM; Wacker, SA1
Arvanitis, AG; Bronson, JJ; Combs, AP; Dasgupta, B; Dzierba, CD; Galka, A; Gilligan, PJ; Johnson, TL; Kasireddy-Polam, P; Lodge, NJ; Macor, JE; Molski, TF; Rafalski, M; Sielecki, TM; Takvorian, AG; Trainor, GL; Vig, S; Wong, H; Zaczek, RC; Zhang, G1
Bertomeu, T; Bucur, O; Dewar, R; Goganau, I; Khosravi-Far, R; Pennarun, B; Petrescu, SM; Stancu, AL1
Klewe, A; Kruse, T; Lindel, T1
Classe, JM; Ferron, G; Floquet, A; Freyer, G; Hardy-Bessard, AC; Kurtz, JE; Lécuru, F; Motte-Rouge, T; Pautier, P1

Reviews

2 review(s) available for pyrazines and pteridines

ArticleYear
Protein-protein complexation in bioluminescence.
    Protein & cell, 2011, Volume: 2, Issue:12

    Topics: Animals; Anthozoa; Aquatic Organisms; Bacteria; Binding Sites; Calcium; Crystallography, X-Ray; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; Hydrozoa; Imidazoles; Luciferases; Luminescent Measurements; Luminescent Proteins; Models, Molecular; Protein Binding; Pteridines; Pyrazines; Scyphozoa; Spectrometry, Fluorescence

2011
Prise en charge médicale de la récidive du cancer épithélial de l'ovaire: Medical management of recurrent epithelial ovarian cancer.
    Bulletin du cancer, 2021, Volume: 108, Issue:9S1

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Azepines; Bevacizumab; Carcinoma, Ovarian Epithelial; Female; Genes, BRCA1; Genes, BRCA2; Humans; Immunoconjugates; Immunotherapy; Isoxazoles; Maintenance Chemotherapy; Maytansine; Neoplasm Recurrence, Local; Ovarian Neoplasms; Platinum Compounds; Poly(ADP-ribose) Polymerase Inhibitors; Pteridines; Pyrazines; Pyrimidines

2021

Other Studies

16 other study(ies) available for pyrazines and pteridines

ArticleYear
Determination of the active portion of the folic acid molecule in cellular slime mold chemotaxis.
    Journal of bacteriology, 1975, Volume: 122, Issue:1

    Topics: Agar; Aminobenzoates; Biological Assay; Cell-Free System; Cellophane; Chemical Phenomena; Chemistry; Chemotaxis; Chromatography, Thin Layer; Cyclic AMP; Drug Synergism; Folic Acid; Glutamates; Myxomycetes; Pteridines; Pyrazines; Pyrimidines; Species Specificity

1975
[Studies on diazabicycloalkanes. I. Pharmacological studies of octahydro-2H-pyrido(1,2-a)pyrazine derivatives and related compounds, especially their antihistaminic activities].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1972, Volume: 92, Issue:11

    Topics: Anesthetics, Local; Animals; Barium; Female; Guinea Pigs; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Male; Muscle, Smooth; Parasympatholytics; Pteridines; Pyrazines; Pyridines; Rats; Serotonin Antagonists; Structure-Activity Relationship

1972
An extreme diminution in the strong affinity of 2-amino-4-hydroxy-6-formylpteridine for xanthine oxidase by reduction of a 7, 8-double bond or a formyl group at position 6 of its pyrazine ring.
    Journal of nutritional science and vitaminology, 1974, Volume: 20, Issue:4

    Topics: Amines; Animals; Binding Sites; Binding, Competitive; Kinetics; Mathematics; Milk; Models, Chemical; Oxidation-Reduction; Polarography; Pteridines; Pyrazines; Structure-Activity Relationship; Xanthine Oxidase; Xanthines

1974
The chain of unexpected discovery: xanthopterin-stimulated renal mitosis.
    Perspectives in biology and medicine, 1972,Winter, Volume: 15, Issue:2

    Topics: Animals; Biochemistry; Creativity; History, 20th Century; Hyperplasia; Hypertrophy; Hypoxanthines; Kidney; Kidney Diseases; Mitosis; Pteridines; Purines; Pyrazines; Pyrimidines; Quinoxalines; Rats; Stimulation, Chemical; Structure-Activity Relationship; United Kingdom; Xanthine Oxidase; Xanthopterin

1972
[Studies on the syntheses of N-heterocyclic compounds. X. Syntheses of 2-phenyl-pyrazino(2,3-d)pyridazine derivatives].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1972, Volume: 92, Issue:11

    Topics: Chemical Phenomena; Chemistry; Pteridines; Pyrazines; Pyridazines

1972
Pteridine studies. XLI. New routes to 4-aminopteridines via 3-(dimethylaminomethyleneamino)pyrazine-2-carbonitrile and related compounds.
    Journal of the Chemical Society. Perkin transactions 1, 1971, Volume: 22

    Topics: Amines; Methods; Nitriles; Pteridines; Pyrazines

1971
Investigations of structures of substituted lumazines by deuterium exchange and nuclear magnetic resonance spectroscopy.
    Biochemistry, 1970, Feb-17, Volume: 9, Issue:4

    Topics: Chemical Phenomena; Chemistry; Chromatography, Paper; Deuterium; Hot Temperature; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Pteridines; Pyrazines; Spectrophotometry; Water

1970
[Acute renal failure after pteridine administration].
    Klinische Wochenschrift, 1970, Oct-15, Volume: 48, Issue:20

    Topics: Acute Kidney Injury; Animals; Anuria; Chlorothiazide; Diuretics; Folic Acid; Furosemide; Glomerular Filtration Rate; Kidney Function Tests; Kidney Tubules; Male; Pteridines; Pyrazines; Rats; Water-Electrolyte Balance; Xanthopterin

1970
Pyrazine diuretics. V. N-Amidino-3-aminopyrazinecarboxamidines and analogous 2,4-diaminopteridines.
    Journal of medicinal chemistry, 1968, Volume: 11, Issue:2

    Topics: Adrenal Glands; Adrenalectomy; Animals; Chemical Phenomena; Chemistry, Physical; Diuretics; Dogs; Pteridines; Pyrazines; Rats; Spironolactone; Triamterene

1968
Pyrazine diuretics. IV. N-amidino-3-amino-6-substituted pyrazinecarboxamides.
    Journal of medicinal chemistry, 1967, Volume: 10, Issue:5

    Topics: Amides; Animals; Carbon; Diuretics; Hydrogen; Nitrogen; Pteridines; Pyrazines; Rats

1967
Discovery of 3,3'-(2,4-diaminopteridine-6,7-diyl)diphenol as an isozyme-selective inhibitor of PI3K for the treatment of ischemia reperfusion injury associated with myocardial infarction.
    Journal of medicinal chemistry, 2007, Sep-06, Volume: 50, Issue:18

    Topics: Animals; Antigens, CD; Cadherins; Capillary Permeability; Cell Proliferation; Cells, Cultured; Endothelial Cells; Humans; Isoenzymes; Male; Models, Molecular; Myocardial Infarction; Myocardial Reperfusion Injury; Phenols; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Pteridines; Pyrazines; Pyridines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Umbilical Veins; Vascular Endothelial Growth Factor A

2007
Pyrimido [4,5-b]pyrazines (pteridines) pteridinemono- and -dicarboxylic acids.
    Journal of the American Chemical Society, 1948, Volume: 70, Issue:9

    Topics: Dicarboxylic Acids; Pteridines; Pyrazines

1948
Using transcriptome sequencing to identify mechanisms of drug action and resistance.
    Nature chemical biology, 2012, Feb-12, Volume: 8, Issue:3

    Topics: Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Cycle Proteins; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pteridines; Pyrazines; Sequence Analysis, DNA; Transcriptome

2012
Synthesis and structure-activity relationships of pyrido[3,2-b]pyrazin-3(4H)-ones and pteridin-7(8H)-ones as corticotropin-releasing factor-1 receptor antagonists.
    Bioorganic & medicinal chemistry letters, 2012, Aug-01, Volume: 22, Issue:15

    Topics: Animals; Anti-Anxiety Agents; Half-Life; Pteridines; Pyrazines; Rats; Receptors, Corticotropin-Releasing Hormone; Structure-Activity Relationship

2012
Combination of bortezomib and mitotic inhibitors down-modulate Bcr-Abl and efficiently eliminates tyrosine-kinase inhibitor sensitive and resistant Bcr-Abl-positive leukemic cells.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Benzamides; Boronic Acids; Bortezomib; Caspases; Cell Death; Cell Line, Tumor; Dasatinib; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Fusion Proteins, bcr-abl; Heterocyclic Compounds, 2-Ring; Humans; Imatinib Mesylate; JNK Mitogen-Activated Protein Kinases; Leukemia; Mitosis; Models, Biological; p38 Mitogen-Activated Protein Kinases; Paclitaxel; Phosphorylation; Piperazines; Protein Kinase Inhibitors; Pteridines; Pyrazines; Pyrimidines; Signal Transduction; STAT5 Transcription Factor; Thiazoles

2013
Aminopyrazine Pathway to the Moco Metabolite Dephospho Form A.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Aug-22, Volume: 23, Issue:47

    Topics: Coenzymes; Fungal Proteins; Metalloproteins; Molybdenum Cofactors; Neurospora crassa; Nitrate Reductase; Oxidation-Reduction; Pteridines; Pyrazines; Recombinant Proteins

2017