pyrazines has been researched along with propranolol in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (60.87) | 18.7374 |
| 1990's | 6 (26.09) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Festen, CM; Slegers, JF | 1 |
| de Sousa, RC; Li, JH | 1 |
| Futaki, S; Goto, Y; Hata, K; Kawaguchi, O; Nishioka, T; Saeki, A; Suga, H; Takasago, T | 1 |
| Das, AM; Harris, DA | 1 |
| Giles, RE; Hwang, TF; Kau, ST; Keith, RA; Murthy, VS; Salama, AI | 1 |
| Giles, RE; Hwang, TF; Kau, ST; Keith, RA; Murthy, VS; Salama, AI; Wurm, R; Zagar, ME | 1 |
| Clineschmidt, BV; Pettibone, DJ; Reiss, DR; Robinson, JL | 1 |
| Davies, GE | 1 |
| Bonta, IL; Frankhuyzen, AL | 1 |
| Davies, GE; Rose, FL; Somerville, AR | 1 |
| Dhasmana, KM; Dixit, KS; Tangri, KK | 1 |
| Naidoo, DN; Seedat, YK | 1 |
| Savoie, LL | 1 |
| Boucard, M; Chapat, JP; Cros, GH; McNeill, JH; Milhavet, JC; Rechenq, E; Sablayrolles, C; Serrano, JJ | 1 |
| Ando, H; Kobayashi-Ando, S; Takeya, K; Yajima, M | 1 |
| Zeng, GY; Zhang, LY; Zhang, Y; Zhou, YP | 1 |
| Ando, H; Ando, S; Nomura, H; Takeya, K; Yajima, M | 1 |
| Dhalla, NS; Elimban, V; Rupp, H | 1 |
| Bompart, J; Bonnet, PA; Boucard, M; Chapat, JP; Hadj-Kaddour, K; Laurent, F; Michel, A | 1 |
| Bolli, GB | 1 |
| Chen, D; Li, X; Zou, J | 1 |
| Chen, L; Huang, F; Li, W; Li, X; Liu, Z; Luo, Z; Wu, H; Xu, Y; Young, C; Zhou, S | 1 |
| Akerman, S; Goadsby, PJ; Martins-Oliveira, M; Zhao, Y | 1 |
1 trial(s) available for pyrazines and propranolol
| Article | Year |
|---|---|
[A randomized controlled study of ligustrazine in combination with propranolol for prevention of recurrent esophageal varices bleeding].
Topics: Adult; Aged; Drug Therapy, Combination; Esophageal and Gastric Varices; Female; Gastrointestinal Hemorrhage; Hemodynamics; Humans; Male; Middle Aged; Propranolol; Prospective Studies; Pyrazines; Recurrence | 2000 |
22 other study(ies) available for pyrazines and propranolol
| Article | Year |
|---|---|
The influence of ions, ouabain, propranolol and amiloride on the transepithelial potential and resistance of rabbit cornea.
Topics: Amiloride; Animals; Chlorides; Cornea; Electric Conductivity; Epithelium; Intraocular Pressure; Membrane Potentials; Ouabain; Potassium; Propranolol; Pyrazines; Rabbits; Sodium; Time Factors | 1979 |
Inhibitory and stimulatory effects of amiloride analogues on sodium transport in frog skin.
Topics: Amiloride; Animals; Anura; Biological Transport, Active; Drug Interactions; In Vitro Techniques; Lanthanum; Oxytocin; Propranolol; Pyrazines; Ranidae; Skin; Sodium; Structure-Activity Relationship | 1979 |
Left ventricular contractility and energetic cost in disease models--an approach from the pressure-volume diagram.
Topics: Animals; Calcium; Disease Models, Animal; Dogs; Epinephrine; Heart Diseases; Myocardial Contraction; Oxygen Consumption; Propranolol; Pyrazines; Quinolines; Rabbits | 1992 |
Control of mitochondrial ATP synthase in heart cells: inactive to active transitions caused by beating or positive inotropic agents.
Topics: Animals; Calcium; Cardiotonic Agents; Cells, Cultured; Enzyme Activation; Isoproterenol; Male; Mitochondria, Heart; Multienzyme Complexes; Myocardial Contraction; NADH, NADPH Oxidoreductases; Propranolol; Proton-Translocating ATPases; Pyrazines; Rats; Rats, Inbred Strains; Ruthenium Red | 1990 |
ICI 147,798: a slowly dissociable beta adrenoceptor antagonist that causes insurmountable beta-1 and surmountable beta-2 adrenoceptor antagonism in isolated tissues.
Topics: Adrenergic beta-Antagonists; Animals; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Norepinephrine; Propranolol; Pyrazines; Rabbits; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta | 1989 |
Insurmountable beta receptor blockade by ICI 147,798 in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Female; Heart Rate; Male; Propranolol; Pyrazines; Rabbits; Receptors, Adrenergic, beta; Theophylline | 1989 |
Characterization of 5-hydroxytryptamine receptors in rat stomach fundus.
Topics: Animals; Binding, Competitive; Brain Chemistry; Gastric Fundus; In Vitro Techniques; Ketanserin; Male; Muscle Contraction; Piperazines; Piperidines; Propranolol; Pyrazines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tritium | 1985 |
Antibronchoconstrictor activity of two new phosphodiesterase inhibitors, a triazolopyrazine (ICI 58 301) and a triazolopyrimidine (ICI 63 197).
Topics: Acetamides; Acetylcholine; Albuterol; Animals; Bronchi; Bronchial Spasm; Cyclic AMP; Epinephrine; Female; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Isoproterenol; Lung; Male; Perfusion; Phosphodiesterase Inhibitors; Practolol; Propranolol; Pyrazines; Pyrimidines | 1973 |
Effect of mianserin, a potent anti-serotonin agent, on the isolated rat stomach fundus preparation.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Animals; Binding Sites; Calcium; Chlorpromazine; Cyproheptadine; Dextroamphetamine; Dibenzazepines; Dioxins; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Methysergide; Morphine; Muscle Contraction; Phenoxybenzamine; Piperidines; Propranolol; Pyrazines; Rats; Receptors, Drug; Scopolamine; Serotonin; Serotonin Antagonists; Stomach; Tryptamines | 1974 |
New inhibitor of phosphodiesterase with anti-bronchoconstrictor properties.
Topics: Acetamides; Animals; Bronchi; Bronchial Spasm; Cyclic AMP; Drug Synergism; Epinephrine; Guinea Pigs; Histamine; Lung; Myocardium; Phosphoric Monoester Hydrolases; Propranolol; Pyrazines; Triazoles | 1971 |
An analysis of the central vasomotor effects of monoamine oxidase inhibitor, modaline sulphate.
Topics: Animals; Atropine; Blood Pressure; Carbachol; Carotid Arteries; Cerebral Ventricles; Dogs; Female; Hemicholinium 3; Injections; Male; Phenoxybenzamine; Propranolol; Pyrazines; Stimulation, Chemical; Tachyphylaxis; Tetrabenazine; Transducers; Vagus Nerve; Vasomotor System | 1972 |
Evaluation of amiloride combined with hydrochlorothiazide (Moduretic) in the treatment of hypertension.
Topics: Adult; Aged; Amiloride; Benzothiadiazines; Diuretics; Drug Combinations; Female; Guanethidine; Humans; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Potassium; Propranolol; Pyrazines; Urea; Uremia | 1973 |
[Role of antikaliuretics and catecholamines in the prevention of cardiac necroses of metabolic origin].
Topics: Adrenal Cortex Hormones; Amiloride; Animals; Catecholamines; Digitoxin; Diuretics; Epinephrine; Heart Diseases; Kidney; Magnesium; Metabolic Diseases; Necrosis; Oils; Phenoxybenzamine; Potassium; Potassium Chloride; Propranolol; Pyrazines; Rats; Sodium; Stress, Physiological | 1971 |
Synthesis of imidazo[1,2-a]pyrazine derivatives with uterine-relaxing, antibronchospastic, and cardiac-stimulating properties.
Topics: Animals; Atrial Function; Bronchial Spasm; Chemical Phenomena; Chemistry; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Female; Guinea Pigs; Heart; Heart Rate; Imidazoles; Isoproterenol; Male; Myocardial Contraction; Propranolol; Pyrazines; Rats; Stimulation, Chemical; Structure-Activity Relationship; Uterine Contraction | 1984 |
Positive inotropic effect of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1 -piperazinyl]-2(1H)-quinolinone (OPC-8212) and mechanism of action in guinea pig ventricular myocardium.
Topics: Animals; Carbachol; Cardiotonic Agents; Cimetidine; Cyclic AMP; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Membrane Potentials; Myocardial Contraction; Propranolol; Pyrazines; Quinolines; Reserpine | 1984 |
[Effects of tetramethylpyrazine on cardiac haemodynamics in dogs (author's transl)].
Topics: Animals; Cardiovascular Agents; Dogs; Hemodynamics; Oxygen Consumption; Propranolol; Pyrazines; Reserpine | 1982 |
Relaxing effect of vesnarinone (OPC-8212) on the tracheal muscle strips isolated from guinea pigs.
Topics: 1-Methyl-3-isobutylxanthine; Airway Resistance; Animals; Carbachol; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Potassium; Propranolol; Pyrazines; Quinolines; Reserpine; Trachea | 1993 |
Modification of myosin isozymes and SR Ca(2+)-pump ATPase of the diabetic rat heart by lipid-lowering interventions.
Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Transporting ATPases; Cyclopropanes; Diabetes Mellitus, Experimental; Epoxy Compounds; Heart; Heart Rate; Hypolipidemic Agents; Imidazoles; Male; Myosins; Propranolol; Pyrazines; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum | 1994 |
Cardiovascular effects of SCA40, a novel potassium channel opener, in rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Dose-Response Relationship, Drug; Drug Interactions; Heart Atria; Heart Rate; Imidazoles; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Parasympatholytics; Potassium Channels; Propranolol; Pyrazines; Rats; Rats, Wistar | 1993 |
Importance of catecholamines in defense against insulin hypoglycemia in humans.
Topics: Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Heparin; Homeostasis; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypolipidemic Agents; Insulin; Lipolysis; Phentolamine; Propranolol; Pyrazines | 1998 |
The novel compound liguzinediol exerts positive inotropic effects in isolated rat heart via sarcoplasmic reticulum Ca2+ ATPase-dependent mechanism.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Caffeine; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart; Male; Myocardial Contraction; Myocytes, Cardiac; Nimodipine; Ouabain; Prazosin; Propranolol; Pyrazines; Rats; Rats, Sprague-Dawley; Ruthenium Red; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Thapsigargin | 2012 |
Comparative effects of traditional Chinese and Western migraine medicines in an animal model of nociceptive trigeminovascular activation.
Topics: Animals; Benzyl Alcohols; Disease Models, Animal; Dura Mater; Glucosides; Levetiracetam; Male; Medicine, Chinese Traditional; Migraine Disorders; Neurons, Afferent; Nociceptive Pain; Pain Management; Propranolol; Pyrazines; Rats, Sprague-Dawley; Trigeminal Nerve | 2018 |