Page last updated: 2024-08-21

pyrazines and pr-957

pyrazines has been researched along with pr-957 in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Al, M; Assaraf, YG; Chan, ET; de Gruijl, TD; den Uyl, D; Dijkmans, BA; Jansen, G; Kirk, CJ; Oerlemans, R; Peters, GJ; Scheffer, GL; Scheper, RJ; van der Heijden, JW; Verbrugge, SE1
Claas, FH; Heidt, S; Mulder, A; Roelen, DL; Vergunst, M1
Anderl, J; Assaraf, YG; Blank, JL; Cloos, J; Jansen, G; Kaspers, GJ; Kirk, CJ; Niewerth, D; van de Ven, PM; van Meerloo, J; Zweegman, S1
Groll, M; Heinemeyer, W; Huber, EM1

Trials

1 trial(s) available for pyrazines and pr-957

ArticleYear
Inactivating PSMB5 mutations and P-glycoprotein (multidrug resistance-associated protein/ATP-binding cassette B1) mediate resistance to proteasome inhibitors: ex vivo efficacy of (immuno)proteasome inhibitors in mononuclear blood cells from patients with
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 341, Issue:1

    Topics: Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Boronic Acids; Bortezomib; Cell Line, Tumor; Drug Resistance, Neoplasm; HEK293 Cells; Humans; Leukocytes, Mononuclear; Mutation; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Treatment Outcome

2012

Other Studies

3 other study(ies) available for pyrazines and pr-957

ArticleYear
Proteasome inhibition profoundly affects activated human B cells.
    Transplantation, 2013, Jun-15, Volume: 95, Issue:11

    Topics: Apoptosis; B-Lymphocytes; Boronic Acids; Bortezomib; Cell Proliferation; Cells, Cultured; Humans; Immunoglobulin G; Immunoglobulin M; In Vitro Techniques; Oligopeptides; Plasma Cells; Proteasome Endopeptidase Complex; Pyrazines

2013
Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines.
    Journal of hematology & oncology, 2014, Jan-13, Volume: 7

    Topics: Apoptosis; Blotting, Western; Boronic Acids; Bortezomib; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Hematologic Neoplasms; Histocompatibility Antigens Class I; HLA Antigens; Humans; Interferon-gamma; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Subunits; Pyrazines; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Up-Regulation

2014
Bortezomib-resistant mutant proteasomes: structural and biochemical evaluation with carfilzomib and ONX 0914.
    Structure (London, England : 1993), 2015, Feb-03, Volume: 23, Issue:2

    Topics: Boronic Acids; Bortezomib; Catalytic Domain; Crystallography, X-Ray; Drug Resistance, Neoplasm; Models, Molecular; Molecular Structure; Mutagenesis; Mutation; Oligopeptides; Proteasome Endopeptidase Complex; Protein Conformation; Pyrazines; X-Ray Diffraction; Yeasts

2015