Page last updated: 2024-08-21

pyrazines and oseltamivir

pyrazines has been researched along with oseltamivir in 24 studies

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (8.33)	29.6817
2010's	13 (54.17)	24.3611
2020's	9 (37.50)	2.80

Authors

Authors	Studies
Egawa, H; Fukuda, Y; Furuta, Y; Kamiyama, T; Kozaki, K; Kuno, M; Minami, S; Nomura, N; Shiraki, K; Takahashi, K	1
Bailey, KW; Barnard, DL; Day, CW; Furuta, Y; Morrey, JD; Sidwell, RW; Smee, DF; Wong, MH	1
Bailey, KW; Furuta, Y; Hurst, BL; Morrey, JD; Smee, DF; Tarbet, EB; Wong, MH	1
Furuta, Y; Kawaoka, Y; Kiso, M; Le, QM; Ozawa, M; Sakabe, S; Sakai-Tagawa, Y; Shinya, K; Takahashi, K	1
Cao, B; Cao, RY; Kumaki, Y; Li, S; Xiao, JH; Zhong, W	1
Barnard, DL; Furuta, Y; Hurst, BL; Smee, DF; Tarbet, EB; Vollmer, AH	1
Bae, JY; Baek, LJ; Cheong, HJ; Heo, J; Hwang, MW; Jang, SI; Kim, D; Kim, H; Kim, JI; Lee, I; Lee, S; Park, MS; Park, S; Song, JW; Song, KJ	1
Cheong, HJ; Choi, WS; Kim, WJ; Noh, JY; Song, JY	1
Garcia-Alcalde, F; Govorkova, EA; Marathe, BM; Najera, I; Vogel, P; Webby, RJ; Webster, RG; Wong, SS	1
Bank, C; Bolon, DN; Finberg, RW; Jensen, JD; Kowalik, TF; Liu, P; Matuszewski, S; Ormond, L; Renzette, N; Wang, JP; Zeldovich, K	1
Favié, LM; Meijer, A; Murk, JL; Nijstad, AL; Sikma, MA; van Maarseveen, EM	1
Hasegawa, H; Ito, M; Kawaoka, Y; Kiso, M; Lopes, TJS; Nakajima, N; Neumann, G; Yamashita, M; Yamayoshi, S	1
Baz, M; Boivin, G; Carbonneau, J; Cavanagh, MH; Rhéaume, C	1
Hayden, FG; Hurt, AC; Mifsud, EJ	1
Daikoku, T; Fukuda, Y; Kawai, M; Morita, N; Nomura, N; Okuda, T; Shiraki, K; Takahashi, K; Takemoto, M; Tanaka, T	1
Cao, B; Chen, C; Fan, G; Guo, L; Hayden, FG; Horby, P; Lu, B; Pan, J; Salam, A; Wang, C; Wang, Y; Zheng, J	1
Martin-Loeches, I; O'Sullivan, S; Rodriguez, A; Torres, A	1
Cheng, YH; Fang, QQ; Huang, WJ; Li, XY; Liu, J; Meng, Y; Tan, MJ; Wang, DY; Wei, HJ	1
Duan, Y; Zhou, C; Zhu, HL	1
Cutrell, JB; Jodlowski, TZ; Monogue, ML; Sanders, JM	1
Abed, Y; Baz, M; Boivin, G; Checkmahomed, L; Padey, B; Pizzorno, A; Rosa-Calatrava, M; Terrier, O	1
Wen, S; Xu, X; Yadav, AK; Yu, L	1
Dabbous, HM; Ebeid, FFS; El Assal, G; El-Sayed, MH; Elgaafary, M; Elghazaly, H; Fawzy, E; Hassany, SM; Riad, AR; Sherief, AF; TagelDin, MA	1
Berk, H; Demir Önder, K; Öztoprak, N; Seremet Keskin, A; Seyman, D	1

Reviews

5 review(s) available for pyrazines and oseltamivir

Article	Year
Antiviral therapy in seasonal influenza and 2009 H1N1 pandemic influenza: Korean experiences and perspectives. Expert review of anti-infective therapy, 2015, Volume: 13, Issue:11 Topics: Acids, Carbocyclic; Amides; Antiviral Agents; Clinical Trials as Topic; Cyclopentanes; Drug Resistance, Viral; Guanidines; Hospitalization; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Oseltamivir; Pyrans; Pyrazines; Republic of Korea; Sialic Acids; Zanamivir	2015
Antivirals targeting the polymerase complex of influenza viruses. Antiviral research, 2019, Volume: 169 Topics: Amides; Antiviral Agents; Dibenzothiepins; DNA-Directed RNA Polymerases; Drug Combinations; Drug Resistance, Viral; Enzyme Inhibitors; Humans; Influenza A virus; Influenza B virus; Morpholines; Neuraminidase; Orthomyxoviridae; Oseltamivir; Oxazines; Pyrazines; Pyridines; Pyridones; Serine Endopeptidases; Thiepins; Triazines	2019
Influenza management with new therapies. Current opinion in pulmonary medicine, 2020, Volume: 26, Issue:3 Topics: Adrenal Cortex Hormones; Amides; Antiviral Agents; Critical Care; Critical Illness; Dibenzothiepins; Enzyme Inhibitors; Humans; Influenza, Human; Morpholines; Neuraminidase; Oseltamivir; Pyrazines; Pyridines; Pyridones; Pyrimidines; Pyrroles; Respiration, Artificial; Triazines; Zanamivir	2020
Pharmacologic Treatments for Coronavirus Disease 2019 (COVID-19): A Review. JAMA, 2020, May-12, Volume: 323, Issue:18 Topics: Adenosine Monophosphate; Adrenal Cortex Hormones; Alanine; Amides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Azithromycin; Betacoronavirus; Chloroquine; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Humans; Hydroxychloroquine; Immunoglobulins; Immunologic Factors; Indoles; Lopinavir; Oseltamivir; Pandemics; Pneumonia, Viral; Pyrazines; Ribavirin; Ritonavir; SARS-CoV-2; Withholding Treatment	2020
Antiviral treatment in COVID-19: which is the most promising?-a narrative review. Annals of palliative medicine, 2021, Volume: 10, Issue:1 Topics: Adenosine Monophosphate; Alanine; Amides; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azetidines; Chloroquine; COVID-19; COVID-19 Serotherapy; Drug Combinations; Humans; Hydroxychloroquine; Immunization, Passive; Indoles; Interferons; Ivermectin; Lopinavir; Nitro Compounds; Oseltamivir; Purines; Pyrazines; Pyrazoles; Ribavirin; Ritonavir; Sulfonamides; Thiazoles	2021

Trials

1 trial(s) available for pyrazines and oseltamivir

Article	Year
Safety and efficacy of favipiravir versus hydroxychloroquine in management of COVID-19: A randomised controlled trial. Scientific reports, 2021, 03-31, Volume: 11, Issue:1 Topics: Adult; Amides; Antiviral Agents; COVID-19; COVID-19 Drug Treatment; Female; Ferritins; Fibrin Fibrinogen Degradation Products; Humans; Hydroxychloroquine; Male; Middle Aged; Oseltamivir; Pyrazines; Treatment Outcome	2021

Other Studies

18 other study(ies) available for pyrazines and oseltamivir

Article	Year
In vitro and in vivo activities of T-705 and oseltamivir against influenza virus. Antiviral chemistry & chemotherapy, 2003, Volume: 14, Issue:5 Topics: Acetamides; Amides; Animals; Antiviral Agents; Drug Evaluation, Preclinical; Influenza A virus; Mice; Orthomyxoviridae Infections; Oseltamivir; Pyrazines; Survival Rate; Time Factors	2003
Efficacy of orally administered T-705 on lethal avian influenza A (H5N1) virus infections in mice. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:3 Topics: Amides; Animals; Antiviral Agents; Cells, Cultured; Cytopathogenic Effect, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Lung; Mice; Mice, Inbred BALB C; Oseltamivir; Oxygen; Pyrazines; Survival Analysis; Virus Replication	2007
Effects of the combination of favipiravir (T-705) and oseltamivir on influenza A virus infections in mice. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:1 Topics: Amides; Animals; Antiviral Agents; Cell Line; Drug Combinations; Drug Interactions; Influenza A virus; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Influenza A Virus, H5N1 Subtype; Mice; Mice, Inbred BALB C; Neuraminidase; Orthomyxoviridae Infections; Oseltamivir; Pyrazines	2010
T-705 (favipiravir) activity against lethal H5N1 influenza A viruses. Proceedings of the National Academy of Sciences of the United States of America, 2010, Jan-12, Volume: 107, Issue:2 Topics: Aged; Amides; Animals; Antiviral Agents; Cell Line; Child; DNA Replication; DNA-Directed DNA Polymerase; Dogs; Drug Resistance, Viral; Humans; Influenza A Virus, H5N1 Subtype; Influenza, Human; Kidney; Kinetics; Lung; Oseltamivir; Pyrazines; Ribavirin	2010
Inhibition of novel reassortant avian influenza H7N9 virus infection in vitro with three antiviral drugs, oseltamivir, peramivir and favipiravir. Antiviral chemistry & chemotherapy, 2014, Dec-16, Volume: 23, Issue:6 Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; Cyclopentanes; Dogs; Drug Resistance, Viral; Guanidines; Influenza A Virus, H7N9 Subtype; Madin Darby Canine Kidney Cells; Oseltamivir; Pyrazines; Reassortant Viruses	2014
In vitro activity of favipiravir and neuraminidase inhibitor combinations against oseltamivir-sensitive and oseltamivir-resistant pandemic influenza A (H1N1) virus. Archives of virology, 2014, Volume: 159, Issue:6 Topics: Amides; Animals; Antiviral Agents; Cell Line; Dogs; Drug Resistance, Viral; Drug Synergism; Enzyme Inhibitors; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Microbial Sensitivity Tests; Oseltamivir; Pyrazines	2014
Combination effects of peramivir and favipiravir against oseltamivir-resistant 2009 pandemic influenza A(H1N1) infection in mice. PloS one, 2014, Volume: 9, Issue:7 Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; Body Weight; Cyclopentanes; Dogs; Drug Resistance, Viral; Drug Synergism; Drug Therapy, Combination; Female; Guanidines; Influenza A Virus, H1N1 Subtype; Lung; Madin Darby Canine Kidney Cells; Mice; Mice, Inbred DBA; Orthomyxoviridae Infections; Oseltamivir; Pyrazines; Survival Rate	2014
Combinations of Oseltamivir and T-705 Extend the Treatment Window for Highly Pathogenic Influenza A(H5N1) Virus Infection in Mice. Scientific reports, 2016, 05-25, Volume: 6 Topics: Amides; Animals; Dogs; Drug Therapy, Combination; Female; Influenza A Virus, H5N1 Subtype; Madin Darby Canine Kidney Cells; Mice; Mice, Inbred BALB C; Orthomyxoviridae Infections; Oseltamivir; Pyrazines	2016
The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution. Genome biology and evolution, 2017, 07-01, Volume: 9, Issue:7 Topics: Amides; Animals; Antiviral Agents; Biological Evolution; Cell Line; Dogs; Genetics, Population; Influenza A virus; Mutation Rate; Orthomyxoviridae Infections; Oseltamivir; Pyrazines	2017
Pharmacokinetics of favipiravir during continuous venovenous haemofiltration in a critically ill patient with influenza. Antiviral therapy, 2018, Volume: 23, Issue:5 Topics: Amides; Antiviral Agents; Critical Illness; Fatal Outcome; Hemofiltration; Humans; Influenza, Human; Intensive Care Units; Male; Middle Aged; Netherlands; Oseltamivir; Pyrazines; Tertiary Care Centers	2018
Combination Therapy With Neuraminidase and Polymerase Inhibitors in Nude Mice Infected With Influenza Virus. The Journal of infectious diseases, 2018, 03-05, Volume: 217, Issue:6 Topics: Amides; Animals; Antiviral Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Female; Guanidines; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Lung; Mice; Mice, Inbred BALB C; Mice, Nude; Neuraminidase; Nucleic Acid Synthesis Inhibitors; Orthomyxoviridae Infections; Oseltamivir; Pyrans; Pyrazines; Sialic Acids; Zanamivir	2018
Combination Therapy with Oseltamivir and Favipiravir Delays Mortality but Does Not Prevent Oseltamivir Resistance in Immunodeficient Mice Infected with Pandemic A(H1N1) Influenza Virus. Viruses, 2018, 11-03, Volume: 10, Issue:11 Topics: Amides; Animals; Antiviral Agents; Cytokines; Disease Models, Animal; Drug Resistance, Viral; Drug Therapy, Combination; Female; Immunocompromised Host; Influenza A Virus, H1N1 Subtype; Mice; Orthomyxoviridae Infections; Oseltamivir; Pyrazines	2018
Growth activation of influenza virus by trypsin and effect of T-705 (favipiravir) on trypsin-optimized growth condition. Acta virologica, 2019, Volume: 63, Issue:3 Topics: Amides; Antiviral Agents; Cell Line; Gene Expression Regulation, Viral; Humans; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Oseltamivir; Pyrazines; RNA, Viral; Trypsin	2019
Comparative Effectiveness of Combined Favipiravir and Oseltamivir Therapy Versus Oseltamivir Monotherapy in Critically Ill Patients With Influenza Virus Infection. The Journal of infectious diseases, 2020, 04-27, Volume: 221, Issue:10 Topics: Aged; Amides; Antiviral Agents; Critical Illness; Drug Therapy, Combination; Female; Humans; Influenza, Human; Male; Middle Aged; Oseltamivir; Pyrazines; Retrospective Studies	2020
Effectiveness of favipiravir (T-705) against wild-type and oseltamivir-resistant influenza B virus in mice. Virology, 2020, Volume: 545 Topics: Amides; Animals; Antiviral Agents; Drug Resistance, Viral; Female; Humans; Influenza B virus; Influenza, Human; Mice; Mice, Inbred C57BL; Oseltamivir; Pyrazines	2020
Advance of promising targets and agents against COVID-19 in China. Drug discovery today, 2020, Volume: 25, Issue:5 Topics: Adenine; Adenosine Monophosphate; Alanine; Amides; Antimalarials; Antiviral Agents; Betacoronavirus; China; Chloroquine; Clinical Trials as Topic; Cobicistat; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; COVID-19 Drug Treatment; Cysteine Endopeptidases; Dibenzothiepins; Drug Combinations; Drug Discovery; Drug Therapy, Combination; Emtricitabine; Humans; Hydroxychloroquine; Indoles; Lopinavir; Medicine, Chinese Traditional; Morpholines; Oseltamivir; Oxazines; Pandemics; Pneumonia, Viral; Pyrazines; Pyridines; Pyridones; Ritonavir; RNA-Dependent RNA Polymerase; SARS-CoV-2; Spike Glycoprotein, Coronavirus; Tenofovir; Thiepins; Triazines; Viral Nonstructural Proteins	2020
In Vitro Combinations of Baloxavir Acid and Other Inhibitors against Seasonal Influenza A Viruses. Viruses, 2020, 10-08, Volume: 12, Issue:10 Topics: Acids, Carbocyclic; Amides; Animals; Antiviral Agents; Cell Line; Dibenzothiepins; Dogs; Drug Combinations; Drug Resistance, Viral; Drug Synergism; Guanidines; Influenza A Virus, H1N1 Subtype; Influenza A Virus, H3N2 Subtype; Madin Darby Canine Kidney Cells; Morpholines; Neuraminidase; Nucleic Acid Synthesis Inhibitors; Orthomyxoviridae Infections; Oseltamivir; Pyrazines; Pyridones; Ribavirin; Triazines; Viral Proteins; Virus Replication; Zanamivir	2020
Retrospective evaluation of seven different treatment protocols in hospitalized COVID-19 patients Turkish journal of medical sciences, 2021, 12-13, Volume: 51, Issue:6 Topics: Adenosine Monophosphate; Adolescent; Adult; Aged; Aged, 80 and over; Alanine; Amides; Antiviral Agents; Clinical Protocols; COVID-19; COVID-19 Nucleic Acid Testing; Female; Humans; Hydroxychloroquine; Length of Stay; Male; Middle Aged; Oseltamivir; Pandemics; Pyrazines; Respiration, Artificial; Retrospective Studies; SARS-CoV-2; Treatment Outcome; Young Adult	2021