pyrazines has been researched along with opc 15161 in 6 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kawaguchi, T; Kido, M; Nakano, Y; Sugawara, M; Sumitomo, J; Takizawa, T; Uetsuki, S | 1 |
| Nakano, Y; Ozawa, T | 1 |
| Hamada, N; Nagase, M | 1 |
| Higuchi, C; Nakano, Y; Nihei, H; Nishimura, H; Omata, M; Sanaka, T; Shinobe, M; Sugino, N | 1 |
| Inuzuka, S; Sugawara, H; Tanikawa, K; Torimura, T; Ueno, T | 1 |
| Kao, WW; Kawashima, Y; Kimura, M; Nakano, Y; Ohkawa, K; Ohnishi, Y; Ooshima, A; Saika, S; Yamanaka, O | 1 |
6 other study(ies) available for pyrazines and opc 15161
| Article | Year |
|---|---|
Novel inhibitors of superoxide anion generation, OPC-15160 and OPC-15161. Taxonomy, fermentation, isolation, physico-chemical properties, biological characteristics and structure determination.
Topics: Animals; Ascomycota; Cells, Cultured; Dose-Response Relationship, Drug; Fermentation; Guinea Pigs; Macrophages; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure; Pyrazines; Solubility; Superoxides; X-Ray Diffraction | 1991 |
The radical scavenging abilities of a new anti-nephritic drug, OPC-15161.
Topics: Bepridil; Biphenyl Compounds; Electron Spin Resonance Spectroscopy; Free Radical Scavengers; Hydroxyl Radical; Picrates; Pyrazines; Superoxides | 1996 |
In vivo effect of OPC15161, a superoxide scavenger, on anti-Thy1 nephritis.
Topics: Albuminuria; Animals; Free Radical Scavengers; Glomerulonephritis; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Pyrazines; Rats; Rats, Wistar; Superoxides; Thy-1 Antigens | 1996 |
Therapeutic effect of a newly developed antioxidative agent (OPC-15161) on experimental immune complex nephritis.
Topics: Animals; Antioxidants; Dipyridamole; Free Radical Scavengers; Immune Complex Diseases; Kidney; Kidney Cortex; Lipid Peroxidation; Male; Malondialdehyde; Nephritis; Phosphatidylcholines; Prednisolone; Proteinuria; Pyrazines; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides | 1997 |
Inhibitory effect of OPC-15161, a component of fungus Thielavia minor, on proliferation and extracellular matrix production of rat cultured hepatic stellate cells.
Topics: Animals; Aspergillus; Calcium; Cell Division; Cells, Cultured; Extracellular Matrix; Growth Inhibitors; Hydroxyproline; Inositol 1,4,5-Trisphosphate; Liver; Male; Pyrazines; Rats; Rats, Wistar | 1998 |
OPC-15161 suppresses the proliferation of Tenon's capsule fibroblasts and the production of type I collagen and fibronectin stimulated by TGF-beta1 in vitro.
Topics: Adult; Cell Count; Cell Division; Cells, Cultured; Connective Tissue; DNA Replication; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fibronectins; Humans; Laminin; Male; Middle Aged; Procollagen; Pyrazines; Tetrazolium Salts; Thiazoles; Transforming Growth Factor beta | 1998 |