Page last updated: 2024-08-21

pyrazines and omeprazole

pyrazines has been researched along with omeprazole in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elm, G; Helander, HF; Mattsson, H; Ottosson, S1
Castrovilly, L; Scott, CK; Sundell, E1
Kim, JW; Lee, DY; Lee, MG1
Acharya, M; Britten, CD; Chan, K; Cohen, N; Dudov, A; Fuloria, J; Gabrail, N; Nemunaitis, J; Quinn, DI; Yee, L1

Trials

1 trial(s) available for pyrazines and omeprazole

ArticleYear
Effect of the cytochrome P450 2C19 inhibitor omeprazole on the pharmacokinetics and safety profile of bortezomib in patients with advanced solid tumours, non-Hodgkin's lymphoma or multiple myeloma.
    Clinical pharmacokinetics, 2009, Volume: 48, Issue:3

    Topics: Aged; Anti-Ulcer Agents; Antineoplastic Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Boronic Acids; Bortezomib; Cross-Over Studies; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Interactions; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Neoplasms; Omeprazole; Proton Pump Inhibitors; Pyrazines

2009

Other Studies

3 other study(ies) available for pyrazines and omeprazole

ArticleYear
Structure and function of rat parietal cells during treatment with omeprazole, SCH 28080, SCH 32651, or ranitidine.
    Scandinavian journal of gastroenterology, 1990, Volume: 25, Issue:8

    Topics: Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Female; H(+)-K(+)-Exchanging ATPase; Imidazoles; Microscopy, Electron; Omeprazole; Parietal Cells, Gastric; Pyrazines; Ranitidine; Rats; Rats, Inbred Strains; Time Factors

1990
Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080.
    Biochemical pharmacology, 1987, Jan-01, Volume: 36, Issue:1

    Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Bucladesine; Dithiothreitol; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Imidazoles; Mercaptoethanol; Microsomes; Omeprazole; Pyrazines; Rabbits

1987
Pharmacokinetic interaction between oltipraz and omeprazole in rats: Competitive inhibition of metabolism of oltipraz by omeprazole via CYP1A1 and 3A2, and of omeprazole by oltipraz via CYP1A1/2, 2D1/2, and 3A1/2.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2007, Volume: 32, Issue:4-5

    Topics: Administration, Oral; Alcohol Oxidoreductases; Animals; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P450 Family 2; Cytochromes; Drug Interactions; Enzyme Inhibitors; Injections, Intravenous; Intestine, Small; Liver; Male; Membrane Proteins; Microsomes; Omeprazole; Pyrazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiones; Thiophenes; Time Factors; Tissue Distribution

2007