pyrazines has been researched along with omeprazole in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elm, G; Helander, HF; Mattsson, H; Ottosson, S | 1 |
| Castrovilly, L; Scott, CK; Sundell, E | 1 |
| Kim, JW; Lee, DY; Lee, MG | 1 |
| Acharya, M; Britten, CD; Chan, K; Cohen, N; Dudov, A; Fuloria, J; Gabrail, N; Nemunaitis, J; Quinn, DI; Yee, L | 1 |
1 trial(s) available for pyrazines and omeprazole
| Article | Year |
|---|---|
Effect of the cytochrome P450 2C19 inhibitor omeprazole on the pharmacokinetics and safety profile of bortezomib in patients with advanced solid tumours, non-Hodgkin's lymphoma or multiple myeloma.
Topics: Aged; Anti-Ulcer Agents; Antineoplastic Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Boronic Acids; Bortezomib; Cross-Over Studies; Cytochrome P-450 CYP2C19; Drug Administration Schedule; Drug Interactions; Female; Humans; Lymphoma, Non-Hodgkin; Male; Middle Aged; Multiple Myeloma; Neoplasms; Omeprazole; Proton Pump Inhibitors; Pyrazines | 2009 |
3 other study(ies) available for pyrazines and omeprazole
| Article | Year |
|---|---|
Structure and function of rat parietal cells during treatment with omeprazole, SCH 28080, SCH 32651, or ranitidine.
Topics: Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Female; H(+)-K(+)-Exchanging ATPase; Imidazoles; Microscopy, Electron; Omeprazole; Parietal Cells, Gastric; Pyrazines; Ranitidine; Rats; Rats, Inbred Strains; Time Factors | 1990 |
Studies on the mechanism of action of the gastric microsomal (H+ + K+)-ATPase inhibitors SCH 32651 and SCH 28080.
Topics: Adenosine Triphosphatases; Aminopyrine; Animals; Bucladesine; Dithiothreitol; Gastric Mucosa; H(+)-K(+)-Exchanging ATPase; Histamine; Imidazoles; Mercaptoethanol; Microsomes; Omeprazole; Pyrazines; Rabbits | 1987 |
Pharmacokinetic interaction between oltipraz and omeprazole in rats: Competitive inhibition of metabolism of oltipraz by omeprazole via CYP1A1 and 3A2, and of omeprazole by oltipraz via CYP1A1/2, 2D1/2, and 3A1/2.
Topics: Administration, Oral; Alcohol Oxidoreductases; Animals; Aryl Hydrocarbon Hydroxylases; Binding, Competitive; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP1A2 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P450 Family 2; Cytochromes; Drug Interactions; Enzyme Inhibitors; Injections, Intravenous; Intestine, Small; Liver; Male; Membrane Proteins; Microsomes; Omeprazole; Pyrazines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Thiones; Thiophenes; Time Factors; Tissue Distribution | 2007 |