Compounds > pyrazines
Page last updated: 2024-08-21

pyrazines and oleanolic acid

pyrazines has been researched along with oleanolic acid in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19901 (11.11)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Bullock, G; Eakins, MN; Sawyer, BC; Slater, TF1
Anderson, KC; Catley, L; Chauhan, D; Gribble, GW; Hideshima, T; Honda, T; Li, G; Mitsiades, C; Munshi, N; Podar, K; Richardson, P; Schlossman, R; Shringarpure, R; Sporn, MB; Suh, N; Tai, YT1
Cai, Z; Cao, S; Hou, P; Lei, H; Ni, J; Tan, Q; Yu, F; Zhang, T1
Cai, Z; Cao, S; Hou, P; Lei, H; Liu, J; Liu, Y; Ni, J; Wang, P; Wang, Y; Zhang, T1
Chu, F; Gong, Y; Gu, S; Lei, H; Li, G; Wang, M; Wang, P; Xu, B; Xu, K; Xu, X; Zhang, H; Zhang, Y1
Bi, S; Chu, F; Guo, W; Lei, H; Li, B; Mao, P; Ren, L; Wang, M; Wang, P; Xu, L; Zhang, H; Zhang, Y1
Dong, XX; Fu, J; Li, FW; Ni, J; Yin, XB; Zeng, ZP1
Cai, DS; Chen, M; Fang, K; Guo, WB; Han, YT; Lei, HM; Ma, T; Wang, H; Wang, PL; Wu, GR; Xue, NN; Yang, YQ; Zhang, XH; Zhang, XY1
Chen, F; Jin, S; Lei, X; Li, G; Li, S; Song, N; Wang, P; Wang, X1

Other Studies

9 other study(ies) available for pyrazines and oleanolic acid

ArticleYear
Studies on bile secretion with the aid of the isolated perfused rat liver. I. Inhibitory action of sporidesmin and icterogenin.
    Proceedings of the Royal Society of London. Series B, Biological sciences, 1974, Jul-30, Volume: 186, Issue:1085

    Topics: Animals; Bile; Bile Ducts, Intrahepatic; Carboxylic Acids; Cholestasis; Female; Indoles; Liver; Mycotoxins; Oleanolic Acid; Perfusion; Pyrazines; Pyrroles; Rats; Secretory Rate; Triterpenes

1974
The bortezomib/proteasome inhibitor PS-341 and triterpenoid CDDO-Im induce synergistic anti-multiple myeloma (MM) activity and overcome bortezomib resistance.
    Blood, 2004, Apr-15, Volume: 103, Issue:8

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Marrow Cells; Boronic Acids; Bortezomib; Cell Division; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Genes, bcl-2; Humans; Imidazoles; Insulin-Like Growth Factor I; Interleukin-6; Lymphocytes; Membrane Potentials; Mitochondria; Multiple Myeloma; Mutation; NF-kappa B; Oleanolic Acid; Protease Inhibitors; Pyrazines; Recombinant Proteins; Transfection

2004
Preparation and evaluation of solid dispersions of a new antitumor compound based on early-stage preparation discovery concept.
    AAPS PharmSciTech, 2013, Volume: 14, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Biological Availability; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Drug Carriers; Drug Discovery; Male; Microscopy, Electron, Scanning; Oleanolic Acid; Povidone; Pyrazines; Rats; Rats, Sprague-Dawley; Solubility; Spectroscopy, Fourier Transform Infrared; Technology, Pharmaceutical; X-Ray Diffraction

2013
In-vitro and in-vivo comparison of T-OA microemulsions and solid dispersions based on EPDC.
    Drug development and industrial pharmacy, 2015, Volume: 41, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Drug Discovery; Electric Conductivity; Emulsions; In Vitro Techniques; Male; Microscopy, Electron, Transmission; Oleanolic Acid; Oleic Acid; Particle Size; Pyrazines; Rats; Rats, Sprague-Dawley; Solubility; Solutions; Viscosity

2015
Amino acid derivatives of ligustrazine-oleanolic acid as new cytotoxic agents.
    Molecules (Basel, Switzerland), 2014, Nov-07, Volume: 19, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Cytotoxins; HeLa Cells; Hep G2 Cells; Humans; Neoplasms; Oleanolic Acid; Pyrazines; Structure-Activity Relationship; Vasodilator Agents

2014
Ligustrazine-Oleanolic Acid Glycine Derivative, G-TOA, Selectively Inhibited the Proliferation and Induced Apoptosis of Activated HSC-T6 Cells.
    Molecules (Basel, Switzerland), 2016, Nov-23, Volume: 21, Issue:11

    Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Cell Survival; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Membrane Potential, Mitochondrial; Oleanolic Acid; Pyrazines; Rats; Signal Transduction

2016
Preparation and physicochemical characterization of T-OA PLGA microspheres.
    Chinese journal of natural medicines, 2017, Volume: 15, Issue:12

    Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Oleanolic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrazines; Solubility; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2017
Design, Synthesis, and Cytotoxic Analysis of Novel Hederagenin⁻Pyrazine Derivatives Based on Partial Least Squares Discriminant Analysis.
    International journal of molecular sciences, 2018, Sep-30, Volume: 19, Issue:10

    Topics: Apoptosis; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Shape; Cluster Analysis; Discriminant Analysis; Drug Design; Humans; Inhibitory Concentration 50; Least-Squares Analysis; Oleanolic Acid; Principal Component Analysis; Pyrazines; Staining and Labeling; Structure-Activity Relationship

2018
Intestinal lymphatic transport study of antitumor lead compound T-OA with liposomes.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; Intestinal Absorption; Liposomes; Lymphatic Vessels; Male; Oleanolic Acid; Pyrazines; Rats; Rats, Sprague-Dawley

2020