pyrazines has been researched along with nsc 181928 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chi, DM; Hamel, E; Ho, HH; Shahrik, LK | 1 |
| Duanmu, C; Hamel, E; Lin, CM | 1 |
| Gupta, RS | 1 |
| Bowdon, BJ; Dansby, L; Hain, R; Temple, C; Waud, WR; Wheeler, GP | 1 |
| Adamson, DJ; Bowdon, BJ; Temple, C; Webster, J; Wheeler, GP | 1 |
| Adamson, DJ; Bowdon, BJ; Temple, CG; Werline, JA; Wheeler, GP | 1 |
| Bowdon, BJ; Temple, C; Werline, JA; Wheeler, GP | 1 |
7 other study(ies) available for pyrazines and nsc 181928
| Article | Year |
|---|---|
Tubulin-dependent hydrolysis of guanosine triphosphate as a screening test to identify new antitubulin compounds with potential as antimitotic agents: application to carbamates of aromatic amines.
Topics: Antineoplastic Agents; Benzimidazoles; GTP Phosphohydrolases; Guanosine Triphosphate; Hydrolysis; Mitosis; Nocodazole; Pyrazines; Quinazolines; Structure-Activity Relationship; Tubulin Modulators | 1989 |
Tubulin polymerization with ATP is mediated through the exchangeable GTP site.
Topics: Adenosine Triphosphate; Animals; Cattle; Cyclic AMP; Glycerol; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Maytansine; Pyrazines; Tubulin | 1986 |
Cross-resistance of nocodazole-resistant mutants of CHO cells toward other microtubule inhibitors: similar mode of action of benzimidazole carbamate derivatives and NSC 181928 and TN-16.
Topics: Animals; Benzimidazoles; Carbamates; Cell Line; Cricetinae; Drug Resistance; Female; Microtubules; Mutation; Nocodazole; Ovary; Podophyllotoxin; Pyrazines; Pyrrolidinones | 1986 |
Comparison of 1,2-dihydropyrido[3,4-b]pyrazines (1-deaza-7,8-dihydropteridines) with several other inhibitors of mitosis.
Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Survival; Colchicine; Mitosis; Pyrazines; Structure-Activity Relationship; Swine; Tubulin; Vincristine | 1987 |
Biological effects and structure-activity relationships of 1,2-dihydropyrido[3,4-b]pyrazines.
Topics: Animals; Benzimidazoles; Binding, Competitive; Cell Division; Cell Survival; Colchicine; Drug Synergism; Leukemia L1210; Leukemia P388; Leukemia, Experimental; Mice; Nocodazole; Pyrazines; Structure-Activity Relationship; Tubulin; Vincristine | 1983 |
Inhibition of mitosis and anticancer activity against experimental neoplasms by ethyl 5-amino-1,2-dihydro-3-[(N-methylanilino)methyl]-pyrido[3,4-b]pyrazin-7-ylcarbamate (NSC 181928).
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; DNA; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Methotrexate; Mice; Mice, Inbred BALB C; Mitosis; Neoplasm Transplantation; Neoplasms, Experimental; Pyrazines | 1982 |
1-Deaza-7,8-dihydropteridines, a new class of mitotic inhibitors with anticancer activity.
Topics: Antineoplastic Agents; Cells, Cultured; Mitosis; Pyrazines | 1981 |