Page last updated: 2024-08-21

pyrazines and mocetinostat

pyrazines has been researched along with mocetinostat in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.85)18.7374
1990's6 (23.08)18.2507
2000's8 (30.77)29.6817
2010's10 (38.46)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Arimori, S; Fehér, J; Hiramatsu, K; Ichimori, K; Nakazawa, H; Ohkubo, T; Prónai, L; Saigusa, Y1
Hori, K; Koga, S; Nakano, M; Uehara, K1
Goto, T; Nakano, M; Sugioka, K; Ushijima, Y1
Uetrecht, JP; Whitfield, D; Zahid, N1
Koga, S; Nakano, M1
Kashima, K; Mori, M; Sato, N; Shimizu, H; Shimomura, Y; Uehara, Y1
Aizawa, S; Handa, H; Imai, T; Kaidow, A; Nabeshima, R; Nakano, M; Sugimoto, K; Toyama, K1
Chabrier, PE; Croci, N; Ding-Zhou, L; Marchand-Verrecchia, C; Margaill, I; Palmier, B; Plotkine, M1
Hasegawa, T; Kambayashi, Y; Kuwano, H; Nagamoto, H; Nakano, M; Sakurai, K; Saniabadi, AR; Takahashi, A; Tsukada, K1
Chen, XL; Han, ZX; Wang, SY; Xu, QL; Zhang, Z; Zheng, H1
Chen, XL; Chen, ZW; Han, ZX; Wang, SY; Zheng, H1
Dang, SC; Qu, JG; Wang, XQ; Zhang, JX1
Dang, SC; Zhang, JX1
Dang, SC; Fan, X; Qu, JG; Wang, XQ; Zhang, JX1
Fishbein, JC; McCraken, J; Muthukumaran, RB; Sostaric, JZ; Velayutham, M; Zweier, JL1
Cheng, F; Feng, L; Guo, Y; Ke, N; Li, Q; Li, S; Li, Y1
Bhalodia, Y; Manek, R; Sheth, N; Vaghasiya, J1
Besterman, J; Brady, H; Buglio, D; Heise, C; Khaskhely, NM; MacBeth, K; Mamidipudi, V; Martell, RE; Younes, A1
Bontscho, J; Kettritz, R; Luft, FC; Manz, RA; Schneider, W; Schreiber, A1
Dang, X; Die, J; Fan, L; Shi, Z; Wang, C; Wang, K1
Chen, Q; Dong, S; Li, J; Li, Y; Yang, X; Zhang, G; Zhang, Y; Zhao, S1
Hu, DH; Lu, CY; Peng, XM; Xi, L; Zheng, ZX1
Atsumi, T; Ishizu, A; Kusunoki, Y; Miyoshi, A; Miyoshi, H; Nakamura, A; Nakazawa, D; Shida, H; Tomaru, U; Yamada, M1
Cao, W; Chen, J; Cui, M; Shi, Q; Wang, C; Wang, X; Zhang, B; Zhang, G; Zhao, Y1
Hara, A; Hattori, M; Kazumura, K; Miwa, T; Morishita, N; Osawa, T; Takeuchi, K; Tsuchiya, H; Wu, Y1
Kang, B; Kuse, M; Moriguchi, M; Takahashi, R1

Other Studies

26 other study(ies) available for pyrazines and mocetinostat

ArticleYear
Time course of superoxide generation by leukocytes--the MCLA chemiluminescence system.
    Inflammation, 1992, Volume: 16, Issue:5

    Topics: Cell Separation; Cell Survival; Cytochrome c Group; Electron Spin Resonance Spectroscopy; Humans; Imidazoles; Leukocytes; Luminescent Measurements; Luminol; Peroxidase; Pyrazines; Superoxides

1992
Highly sensitive chemiluminescence method for determining myeloperoxidase in human polymorphonuclear leukocytes.
    Analytical biochemistry, 1991, Volume: 199, Issue:2

    Topics: Deferoxamine; Free Radicals; Humans; Hydrogen Peroxide; Imidazoles; Neutrophils; Oxygen; Peroxidase; Pyrazines; Sensitivity and Specificity; Subcellular Fractions; Substrate Specificity; Superoxide Dismutase

1991
Chemiluminescence probe with Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, for estimating the ability of human granulocytes to generate O2-.
    Analytical biochemistry, 1986, Volume: 159, Issue:2

    Topics: Granulocytes; Humans; Hydrogen Peroxide; Luminescent Measurements; Peroxidase; Phagocytosis; Pyrazines; Superoxides; Xanthine Oxidase; Zymosan

1986
Metabolism of vesnarinone by activated neutrophils: implications for vesnarinone-induced agranulocytosis.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3

    Topics: Agranulocytosis; Albumins; Cardiotonic Agents; Chromatography, High Pressure Liquid; Glutathione; Humans; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Influenza Vaccines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Binding; Pyrazines; Quinolines

1994
Luciferin derivative for assay of myeloperoxidase and dopamine metabolism.
    Methods in enzymology, 1994, Volume: 233

    Topics: Basidiomycota; Dopamine; Electron Spin Resonance Spectroscopy; Humans; Imidazoles; Indicators and Reagents; Luminescent Measurements; Monophenol Monooxygenase; Neutrophils; Oxygen; Peroxidase; Photochemistry; Pyrazines; Singlet Oxygen; Superoxides

1994
Hypertonic glucose inhibits the production of oxygen-derived free radicals by rat neutrophils.
    Life sciences, 1993, Volume: 52, Issue:18

    Topics: Animals; Cytochrome c Group; Free Radicals; Glucose Solution, Hypertonic; Hypertonic Solutions; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Peroxidase; Pyrazines; Rats; Rats, Wistar; Reactive Oxygen Species; Sucrose; Superoxides; Time Factors

1993
Effects of vesnarinone on the bone marrow stromal cell-dependent proliferation and differentiation of HL60 cells in vitro.
    Experimental hematology, 1997, Volume: 25, Issue:6

    Topics: Bone Marrow; Bone Marrow Cells; Cardiotonic Agents; Cell Differentiation; Cell Division; Cells, Cultured; Gene Expression; HL-60 Cells; Humans; Macrophage-1 Antigen; Muramidase; Oxidation-Reduction; Peroxidase; Pyrazines; Quinolines

1997
Neuroprotective effects of (S)-N-[4-[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)carbonyl]-1-piperazinyl]phenyl]-2-thiophenecarboximid-amide (BN 80933), an inhibitor of neuronal nitric-oxide synthase and an antioxidant, in model of
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 306, Issue:2

    Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Edema; Brain Infarction; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Mice; Nervous System Diseases; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peroxidase; Pyrazines; Thiophenes

2003
Effects of OPC-6535 on lipopolysaccharide-induced acute liver injury in the rat: involvement of superoxide and tumor necrosis factor-alpha from hepatic macrophages.
    Surgery, 2003, Volume: 134, Issue:5

    Topics: Animals; Chemokine CXCL1; Chemokines, CXC; Imidazoles; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Liver; Luminescent Measurements; Macrophages; Male; Nitroblue Tetrazolium; Perfusion; Peroxidase; Pyrazines; Rats; Rats, Wistar; Superoxides; Thiazoles; Tumor Necrosis Factor-alpha

2003
Ligustrazine attenuates acute lung injury after burn trauma.
    Burns : journal of the International Society for Burn Injuries, 2005, Volume: 31, Issue:4

    Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Capillary Permeability; Interleukin-8; Lung; Male; Models, Animal; Peroxidase; Pyrazines; Random Allocation; Rats; Rats, Wistar; Respiratory Distress Syndrome

2005
Effect of Ligustrazine on liver injury after burn trauma.
    Burns : journal of the International Society for Burn Injuries, 2006, Volume: 32, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Liver; Male; NF-kappa B; Peroxidase; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley

2006
Preventive effect of tetramethylpyrazine on intestinal mucosal injury in rats with acute necrotizing pancreatitis.
    World journal of gastroenterology, 2006, Oct-21, Volume: 12, Issue:39

    Topics: Animals; Female; Gene Expression Regulation, Enzymologic; Intestinal Mucosa; Male; Microcirculation; Neutrophils; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Pyrazines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasodilator Agents

2006
Ligustrazine alleviates acute lung injury in a rat model of acute necrotizing pancreatitis.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2006, Volume: 5, Issue:4

    Topics: Animals; Female; Fibrinolytic Agents; Ligusticum; Lung; Male; Microcirculation; Pancreatitis, Acute Necrotizing; Peroxidase; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome

2006
Ligustrazine alleviates gastric mucosal injury in a rat model of acute necrotizing pancreatitis.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2007, Volume: 6, Issue:2

    Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Female; Gastric Mucosa; Inflammation Mediators; Interleukin-1beta; Ligusticum; Male; Microcirculation; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Phytotherapy; Pyrazines; Rats; Rats, Sprague-Dawley; Regional Blood Flow

2007
Interactions of the major metabolite of the cancer chemopreventive drug oltipraz with cytochrome c: a novel pathway for cancer chemoprevention.
    Free radical biology & medicine, 2007, Oct-01, Volume: 43, Issue:7

    Topics: Animals; Anticarcinogenic Agents; Antioxidants; Chemoprevention; Cytochromes c; Electron Spin Resonance Spectroscopy; Electron Transport; Heart; Horses; Mass Spectrometry; Mitochondria; Neoplasms; Oxidation-Reduction; Peroxidase; Pyrazines; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Thiones; Thiophenes

2007
The protective mechanism of ligustrazine against renal ischemia/reperfusion injury.
    The Journal of surgical research, 2011, Volume: 166, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Disease Models, Animal; Gene Expression; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; Kidney Transplantation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neutrophils; Oxidative Stress; Peroxidase; Pyrazines; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2011
Sitagliptin protects renal ischemia reperfusion induced renal damage in diabetes.
    Regulatory peptides, 2011, Jan-17, Volume: 166, Issue:1-3

    Topics: Animals; Apoptosis; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; DNA Fragmentation; Female; Glutathione; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Peroxidase; Pyrazines; Rats; Rats, Wistar; Reperfusion Injury; Sitagliptin Phosphate; Superoxide Dismutase; Triazoles; Xanthine Oxidase

2011
The class-I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6-independent mechanism.
    British journal of haematology, 2010, Volume: 151, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Benzamides; Boronic Acids; Bortezomib; Cytokines; Drug Screening Assays, Antitumor; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Hodgkin Disease; Humans; NF-kappa B; Protease Inhibitors; Pyrazines; Pyrimidines; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation

2010
Myeloperoxidase-specific plasma cell depletion by bortezomib protects from anti-neutrophil cytoplasmic autoantibodies-induced glomerulonephritis.
    Journal of the American Society of Nephrology : JASN, 2011, Volume: 22, Issue:2

    Topics: Animals; Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Bone Marrow Cells; Boronic Acids; Bortezomib; Enzyme-Linked Immunospot Assay; Glomerulonephritis; Macrophages; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Peroxidase; Plasma Cells; Protease Inhibitors; Pyrazines; Spleen

2011
Tetramethylpyrazine protects spinal cord and reduces inflammation in a rat model of spinal cord ischemia-reperfusion injury.
    Journal of vascular surgery, 2011, Volume: 54, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Male; Neurologic Examination; Neuroprotective Agents; Neutrophil Infiltration; NF-kappa B; Peroxidase; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spinal Cord; Spinal Cord Ischemia; Time Factors; Tumor Necrosis Factor-alpha

2011
A modified "double-hit" induced acute lung injury model in rats and protective effects of tetramethylpyrazine on the injury via Rho/ROCK pathway.
    International journal of clinical and experimental pathology, 2015, Volume: 8, Issue:5

    Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cytoprotection; Down-Regulation; Injections, Intraperitoneal; Lipopolysaccharides; Lung; Male; Neutrophil Infiltration; Neutrophils; Peroxidase; Pyrazines; Rats, Wistar; Respiratory Rate; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction

2015
[Protective effects of perfluorocarbon combined with ligustrazine against lung ischemia-reperfusion injury in rats].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2016, Volume: 36, Issue:2

    Topics: Animals; Cytokines; Fluorocarbons; Lung Injury; Malondialdehyde; Peroxidase; Protective Agents; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2016
Circulating Neutrophil Extracellular Trap Levels in Well-Controlled Type 2 Diabetes and Pathway Involved in Their Formation Induced by High-Dose Glucose.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 2016, Volume: 83, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; DNA; Dose-Response Relationship, Drug; Extracellular Traps; Glucose; Humans; Hypoglycemic Agents; Middle Aged; Neutrophils; Peroxidase; Polymers; Pyrazines; Pyrroles; Quinazolines; Risk Factors; Spiro Compounds; Time Factors

2016
Ligustrazine alleviates acute pancreatitis by accelerating acinar cell apoptosis at early phase via the suppression of p38 and Erk MAPK pathways.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2016, Volume: 82

    Topics: Acinar Cells; Acute Disease; Amylases; Animals; Apoptosis; Cell Line; Cytokines; Disease Models, Animal; Down-Regulation; Inflammation Mediators; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pancreatitis; Peroxidase; Phosphorylation; Pyrazines; Rats, Sprague-Dawley

2016
Rapid on-site dual optical system to measure specific reactive oxygen species (O2-• and OCl-) in a tiny droplet of whole blood.
    PloS one, 2018, Volume: 13, Issue:8

    Topics: Aniline Compounds; Area Under Curve; Diet; Exercise; Fluoresceins; HL-60 Cells; Humans; Hypochlorous Acid; Imidazoles; Luminescent Measurements; Neutrophils; Peroxidase; Pyrazines; ROC Curve; Singlet Oxygen

2018
Expression of recombinant apopholasin using a baculovirus-silkworm multigene expression system and activation via dehydrocoelenterazine.
    Bioorganic & medicinal chemistry letters, 2020, 06-15, Volume: 30, Issue:12

    Topics: Animals; Baculoviridae; Bombyx; Dithiothreitol; Firefly Luciferin; Gene Expression Regulation; Hydrogen Peroxide; Imidazoles; Luminescent Measurements; Luminescent Proteins; Mollusca; Peroxidase; Pyrazines; Recombinant Proteins; Structure-Activity Relationship

2020