pyrazines has been researched along with mocetinostat in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 6 (23.08) | 18.2507 |
| 2000's | 8 (30.77) | 29.6817 |
| 2010's | 10 (38.46) | 24.3611 |
| 2020's | 1 (3.85) | 2.80 |
| Authors | Studies |
|---|---|
| Arimori, S; Fehér, J; Hiramatsu, K; Ichimori, K; Nakazawa, H; Ohkubo, T; Prónai, L; Saigusa, Y | 1 |
| Hori, K; Koga, S; Nakano, M; Uehara, K | 1 |
| Goto, T; Nakano, M; Sugioka, K; Ushijima, Y | 1 |
| Uetrecht, JP; Whitfield, D; Zahid, N | 1 |
| Koga, S; Nakano, M | 1 |
| Kashima, K; Mori, M; Sato, N; Shimizu, H; Shimomura, Y; Uehara, Y | 1 |
| Aizawa, S; Handa, H; Imai, T; Kaidow, A; Nabeshima, R; Nakano, M; Sugimoto, K; Toyama, K | 1 |
| Chabrier, PE; Croci, N; Ding-Zhou, L; Marchand-Verrecchia, C; Margaill, I; Palmier, B; Plotkine, M | 1 |
| Hasegawa, T; Kambayashi, Y; Kuwano, H; Nagamoto, H; Nakano, M; Sakurai, K; Saniabadi, AR; Takahashi, A; Tsukada, K | 1 |
| Chen, XL; Han, ZX; Wang, SY; Xu, QL; Zhang, Z; Zheng, H | 1 |
| Chen, XL; Chen, ZW; Han, ZX; Wang, SY; Zheng, H | 1 |
| Dang, SC; Qu, JG; Wang, XQ; Zhang, JX | 1 |
| Dang, SC; Zhang, JX | 1 |
| Dang, SC; Fan, X; Qu, JG; Wang, XQ; Zhang, JX | 1 |
| Fishbein, JC; McCraken, J; Muthukumaran, RB; Sostaric, JZ; Velayutham, M; Zweier, JL | 1 |
| Cheng, F; Feng, L; Guo, Y; Ke, N; Li, Q; Li, S; Li, Y | 1 |
| Bhalodia, Y; Manek, R; Sheth, N; Vaghasiya, J | 1 |
| Besterman, J; Brady, H; Buglio, D; Heise, C; Khaskhely, NM; MacBeth, K; Mamidipudi, V; Martell, RE; Younes, A | 1 |
| Bontscho, J; Kettritz, R; Luft, FC; Manz, RA; Schneider, W; Schreiber, A | 1 |
| Dang, X; Die, J; Fan, L; Shi, Z; Wang, C; Wang, K | 1 |
| Chen, Q; Dong, S; Li, J; Li, Y; Yang, X; Zhang, G; Zhang, Y; Zhao, S | 1 |
| Hu, DH; Lu, CY; Peng, XM; Xi, L; Zheng, ZX | 1 |
| Atsumi, T; Ishizu, A; Kusunoki, Y; Miyoshi, A; Miyoshi, H; Nakamura, A; Nakazawa, D; Shida, H; Tomaru, U; Yamada, M | 1 |
| Cao, W; Chen, J; Cui, M; Shi, Q; Wang, C; Wang, X; Zhang, B; Zhang, G; Zhao, Y | 1 |
| Hara, A; Hattori, M; Kazumura, K; Miwa, T; Morishita, N; Osawa, T; Takeuchi, K; Tsuchiya, H; Wu, Y | 1 |
| Kang, B; Kuse, M; Moriguchi, M; Takahashi, R | 1 |
26 other study(ies) available for pyrazines and mocetinostat
| Article | Year |
|---|---|
Time course of superoxide generation by leukocytes--the MCLA chemiluminescence system.
Topics: Cell Separation; Cell Survival; Cytochrome c Group; Electron Spin Resonance Spectroscopy; Humans; Imidazoles; Leukocytes; Luminescent Measurements; Luminol; Peroxidase; Pyrazines; Superoxides | 1992 |
Highly sensitive chemiluminescence method for determining myeloperoxidase in human polymorphonuclear leukocytes.
Topics: Deferoxamine; Free Radicals; Humans; Hydrogen Peroxide; Imidazoles; Neutrophils; Oxygen; Peroxidase; Pyrazines; Sensitivity and Specificity; Subcellular Fractions; Substrate Specificity; Superoxide Dismutase | 1991 |
Chemiluminescence probe with Cypridina luciferin analog, 2-methyl-6-phenyl-3,7-dihydroimidazo[1,2-a]pyrazin-3-one, for estimating the ability of human granulocytes to generate O2-.
Topics: Granulocytes; Humans; Hydrogen Peroxide; Luminescent Measurements; Peroxidase; Phagocytosis; Pyrazines; Superoxides; Xanthine Oxidase; Zymosan | 1986 |
Metabolism of vesnarinone by activated neutrophils: implications for vesnarinone-induced agranulocytosis.
Topics: Agranulocytosis; Albumins; Cardiotonic Agents; Chromatography, High Pressure Liquid; Glutathione; Humans; Hydrogen Peroxide; Hypochlorous Acid; In Vitro Techniques; Influenza Vaccines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Neutrophil Activation; Neutrophils; Oxidation-Reduction; Peroxidase; Protein Binding; Pyrazines; Quinolines | 1994 |
Luciferin derivative for assay of myeloperoxidase and dopamine metabolism.
Topics: Basidiomycota; Dopamine; Electron Spin Resonance Spectroscopy; Humans; Imidazoles; Indicators and Reagents; Luminescent Measurements; Monophenol Monooxygenase; Neutrophils; Oxygen; Peroxidase; Photochemistry; Pyrazines; Singlet Oxygen; Superoxides | 1994 |
Hypertonic glucose inhibits the production of oxygen-derived free radicals by rat neutrophils.
Topics: Animals; Cytochrome c Group; Free Radicals; Glucose Solution, Hypertonic; Hypertonic Solutions; Luminescent Measurements; Luminol; Male; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidation-Reduction; Peroxidase; Pyrazines; Rats; Rats, Wistar; Reactive Oxygen Species; Sucrose; Superoxides; Time Factors | 1993 |
Effects of vesnarinone on the bone marrow stromal cell-dependent proliferation and differentiation of HL60 cells in vitro.
Topics: Bone Marrow; Bone Marrow Cells; Cardiotonic Agents; Cell Differentiation; Cell Division; Cells, Cultured; Gene Expression; HL-60 Cells; Humans; Macrophage-1 Antigen; Muramidase; Oxidation-Reduction; Peroxidase; Pyrazines; Quinolines | 1997 |
Neuroprotective effects of (S)-N-[4-[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)carbonyl]-1-piperazinyl]phenyl]-2-thiophenecarboximid-amide (BN 80933), an inhibitor of neuronal nitric-oxide synthase and an antioxidant, in model of
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Edema; Brain Infarction; Infarction, Middle Cerebral Artery; Ischemic Attack, Transient; Male; Mice; Nervous System Diseases; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Peroxidase; Pyrazines; Thiophenes | 2003 |
Effects of OPC-6535 on lipopolysaccharide-induced acute liver injury in the rat: involvement of superoxide and tumor necrosis factor-alpha from hepatic macrophages.
Topics: Animals; Chemokine CXCL1; Chemokines, CXC; Imidazoles; Intercellular Signaling Peptides and Proteins; Lipopolysaccharides; Liver; Luminescent Measurements; Macrophages; Male; Nitroblue Tetrazolium; Perfusion; Peroxidase; Pyrazines; Rats; Rats, Wistar; Superoxides; Thiazoles; Tumor Necrosis Factor-alpha | 2003 |
Ligustrazine attenuates acute lung injury after burn trauma.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Capillary Permeability; Interleukin-8; Lung; Male; Models, Animal; Peroxidase; Pyrazines; Random Allocation; Rats; Rats, Wistar; Respiratory Distress Syndrome | 2005 |
Effect of Ligustrazine on liver injury after burn trauma.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Burns; Liver; Male; NF-kappa B; Peroxidase; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley | 2006 |
Preventive effect of tetramethylpyrazine on intestinal mucosal injury in rats with acute necrotizing pancreatitis.
Topics: Animals; Female; Gene Expression Regulation, Enzymologic; Intestinal Mucosa; Male; Microcirculation; Neutrophils; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Pyrazines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Vasodilator Agents | 2006 |
Ligustrazine alleviates acute lung injury in a rat model of acute necrotizing pancreatitis.
Topics: Animals; Female; Fibrinolytic Agents; Ligusticum; Lung; Male; Microcirculation; Pancreatitis, Acute Necrotizing; Peroxidase; Plant Extracts; Pyrazines; Rats; Rats, Sprague-Dawley; Respiratory Distress Syndrome | 2006 |
Ligustrazine alleviates gastric mucosal injury in a rat model of acute necrotizing pancreatitis.
Topics: Animals; Calcium Channel Blockers; Disease Models, Animal; Female; Gastric Mucosa; Inflammation Mediators; Interleukin-1beta; Ligusticum; Male; Microcirculation; Pancreas; Pancreatitis, Acute Necrotizing; Peroxidase; Phytotherapy; Pyrazines; Rats; Rats, Sprague-Dawley; Regional Blood Flow | 2007 |
Interactions of the major metabolite of the cancer chemopreventive drug oltipraz with cytochrome c: a novel pathway for cancer chemoprevention.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Chemoprevention; Cytochromes c; Electron Spin Resonance Spectroscopy; Electron Transport; Heart; Horses; Mass Spectrometry; Mitochondria; Neoplasms; Oxidation-Reduction; Peroxidase; Pyrazines; Reactive Oxygen Species; Spectrophotometry, Ultraviolet; Thiones; Thiophenes | 2007 |
The protective mechanism of ligustrazine against renal ischemia/reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Disease Models, Animal; Gene Expression; Intercellular Adhesion Molecule-1; Kidney; Kidney Diseases; Kidney Transplantation; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neutrophils; Oxidative Stress; Peroxidase; Pyrazines; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2011 |
Sitagliptin protects renal ischemia reperfusion induced renal damage in diabetes.
Topics: Animals; Apoptosis; Catalase; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; DNA Fragmentation; Female; Glutathione; Glutathione Peroxidase; Kidney; Kidney Diseases; Lipid Peroxidation; Male; Oxidative Stress; Peroxidase; Pyrazines; Rats; Rats, Wistar; Reperfusion Injury; Sitagliptin Phosphate; Superoxide Dismutase; Triazoles; Xanthine Oxidase | 2011 |
The class-I HDAC inhibitor MGCD0103 induces apoptosis in Hodgkin lymphoma cell lines and synergizes with proteasome inhibitors by an HDAC6-independent mechanism.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Boronic Acids; Bortezomib; Cytokines; Drug Screening Assays, Antitumor; Drug Synergism; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Histone Deacetylases; Hodgkin Disease; Humans; NF-kappa B; Protease Inhibitors; Pyrazines; Pyrimidines; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Up-Regulation | 2010 |
Myeloperoxidase-specific plasma cell depletion by bortezomib protects from anti-neutrophil cytoplasmic autoantibodies-induced glomerulonephritis.
Topics: Animals; Antibodies, Antineutrophil Cytoplasmic; Autoantibodies; Bone Marrow Cells; Boronic Acids; Bortezomib; Enzyme-Linked Immunospot Assay; Glomerulonephritis; Macrophages; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; Peroxidase; Plasma Cells; Protease Inhibitors; Pyrazines; Spleen | 2011 |
Tetramethylpyrazine protects spinal cord and reduces inflammation in a rat model of spinal cord ischemia-reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Inflammation Mediators; Interleukin-10; Interleukin-1beta; Male; Neurologic Examination; Neuroprotective Agents; Neutrophil Infiltration; NF-kappa B; Peroxidase; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Spinal Cord; Spinal Cord Ischemia; Time Factors; Tumor Necrosis Factor-alpha | 2011 |
A modified "double-hit" induced acute lung injury model in rats and protective effects of tetramethylpyrazine on the injury via Rho/ROCK pathway.
Topics: Acute Lung Injury; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; Cytoprotection; Down-Regulation; Injections, Intraperitoneal; Lipopolysaccharides; Lung; Male; Neutrophil Infiltration; Neutrophils; Peroxidase; Pyrazines; Rats, Wistar; Respiratory Rate; rho-Associated Kinases; rhoA GTP-Binding Protein; RNA, Messenger; Signal Transduction | 2015 |
[Protective effects of perfluorocarbon combined with ligustrazine against lung ischemia-reperfusion injury in rats].
Topics: Animals; Cytokines; Fluorocarbons; Lung Injury; Malondialdehyde; Peroxidase; Protective Agents; Pyrazines; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Tumor Necrosis Factor-alpha | 2016 |
Circulating Neutrophil Extracellular Trap Levels in Well-Controlled Type 2 Diabetes and Pathway Involved in Their Formation Induced by High-Dose Glucose.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathies; DNA; Dose-Response Relationship, Drug; Extracellular Traps; Glucose; Humans; Hypoglycemic Agents; Middle Aged; Neutrophils; Peroxidase; Polymers; Pyrazines; Pyrroles; Quinazolines; Risk Factors; Spiro Compounds; Time Factors | 2016 |
Ligustrazine alleviates acute pancreatitis by accelerating acinar cell apoptosis at early phase via the suppression of p38 and Erk MAPK pathways.
Topics: Acinar Cells; Acute Disease; Amylases; Animals; Apoptosis; Cell Line; Cytokines; Disease Models, Animal; Down-Regulation; Inflammation Mediators; MAP Kinase Signaling System; p38 Mitogen-Activated Protein Kinases; Pancreatitis; Peroxidase; Phosphorylation; Pyrazines; Rats, Sprague-Dawley | 2016 |
Rapid on-site dual optical system to measure specific reactive oxygen species (O2-• and OCl-) in a tiny droplet of whole blood.
Topics: Aniline Compounds; Area Under Curve; Diet; Exercise; Fluoresceins; HL-60 Cells; Humans; Hypochlorous Acid; Imidazoles; Luminescent Measurements; Neutrophils; Peroxidase; Pyrazines; ROC Curve; Singlet Oxygen | 2018 |
Expression of recombinant apopholasin using a baculovirus-silkworm multigene expression system and activation via dehydrocoelenterazine.
Topics: Animals; Baculoviridae; Bombyx; Dithiothreitol; Firefly Luciferin; Gene Expression Regulation; Hydrogen Peroxide; Imidazoles; Luminescent Measurements; Luminescent Proteins; Mollusca; Peroxidase; Pyrazines; Recombinant Proteins; Structure-Activity Relationship | 2020 |