pyrazines has been researched along with mk 2206 in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deavers, MT; Gershenson, DM; King, ER; Malpica, A; Mok, SC; Tsang, YT; Wong, KK; Zu, Z | 1 |
| Brown, S; Cosulich, SC; Crafter, C; Davies, BR; Dudley, P; Fairley, G; Faulder, P; Fillery, S; Greenwood, H; Hawkins, J; James, M; Johnson, K; Kettle, JG; Lane, CD; Pass, M; Pink, JH; Plant, H | 1 |
| Gleyzer, N; Scarpulla, RC | 1 |
| Davaadelger, B; Duan, L; Gitelis, S; Maki, CG; Perez, RE; Zhou, Y | 1 |
4 other study(ies) available for pyrazines and mk 2206
| Article | Year |
|---|---|
The insulin-like growth factor 1 pathway is a potential therapeutic target for low-grade serous ovarian carcinoma.
Topics: Cell Growth Processes; Cell Line, Tumor; Cystadenocarcinoma, Serous; Female; Gene Expression Profiling; Gene Knockdown Techniques; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Insulin-Like Growth Factor I; Molecular Targeted Therapy; Ovarian Neoplasms; Proto-Oncogene Proteins c-akt; Pyrazines; Receptor, IGF Type 1; Signal Transduction; Up-Regulation | 2011 |
Diverse heterocyclic scaffolds as allosteric inhibitors of AKT.
Topics: Allosteric Regulation; Animals; Biological Availability; Biomarkers; Cell Line, Tumor; Drug Screening Assays, Antitumor; Heterocyclic Compounds, 3-Ring; Heterocyclic Compounds, 4 or More Rings; Humans; Imidazoles; Mice; Mice, Nude; Models, Molecular; Neoplasm Transplantation; Proto-Oncogene Proteins c-akt; Pyrazines; Pyrazoles; Pyridazines; Pyridines; Quinazolines; Rats; Structure-Activity Relationship; Transplantation, Heterologous | 2012 |
Concerted Action of PGC-1-related Coactivator (PRC) and c-MYC in the Stress Response to Mitochondrial Dysfunction.
Topics: Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Tumor; Glycogen Synthase Kinase 3 beta; Heterocyclic Compounds, 3-Ring; Humans; Mitochondria; Phosphorylation; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Pyrazines; Signal Transduction; Stress, Physiological; Sulfonamides; Thiazoles; Transcription Factors | 2016 |
The IGF-1R/AKT pathway has opposing effects on Nutlin-3a-induced apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Drug Synergism; Heterocyclic Compounds, 3-Ring; Humans; Imidazoles; Osteosarcoma; Piperazines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrazines; Receptor, IGF Type 1; Receptors, Somatomedin | 2017 |