Compounds > pyrazines
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pyrazines and mg 262

pyrazines has been researched along with mg 262 in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bennink, JR; Chen, W; Crews, CM; Myung, J; Princiotta, MF; Schubert, U; Yewdell, JW1
Chagin, AS; Chrysis, D; Dantuma, NP; Eriksson, E; Fadeel, B; Menendez-Benito, V; Sävendahl, L; Takigawa, M; Zaman, F1
Fadeel, B; Sävendahl, L; Zaman, F1
Baumann, G; Fechner, M; Grimbo, N; Ludwig, A; Meiners, S; Stangl, K; Stangl, V; Wilck, N1
Horak, KM; Huang, W; Li, J; Liang, Q; Molkentin, JD; Su, H; Tang, M; Tian, Z; Wang, X1

Other Studies

5 other study(ies) available for pyrazines and mg 262

ArticleYear
Cells adapted to the proteasome inhibitor 4-hydroxy- 5-iodo-3-nitrophenylacetyl-Leu-Leu-leucinal-vinyl sulfone require enzymatically active proteasomes for continued survival.
    Proceedings of the National Academy of Sciences of the United States of America, 2001, Jan-16, Volume: 98, Issue:2

    Topics: Amino Acid Chloromethyl Ketones; Aminopeptidases; Animals; Antigen Presentation; Antigens; Boronic Acids; Bortezomib; CD8-Positive T-Lymphocytes; Cell Survival; Cysteine Endopeptidases; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Drug Resistance; Endopeptidases; Enzyme Activation; H-2 Antigens; Leupeptins; Lymphoma, T-Cell; Mice; Multienzyme Complexes; Neoplasm Proteins; Oligopeptides; Peptide Fragments; Phenols; Protease Inhibitors; Proteasome Endopeptidase Complex; Protein Processing, Post-Translational; Pyrazines; Selection, Genetic; Serine Endopeptidases; Sulfones; Thymus Neoplasms; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tyramine; Ubiquitins

2001
Proteasome inhibition up-regulates p53 and apoptosis-inducing factor in chondrocytes causing severe growth retardation in mice.
    Cancer research, 2007, Oct-15, Volume: 67, Issue:20

    Topics: Animals; Apoptosis; Apoptosis Inducing Factor; Boronic Acids; Bortezomib; Chondrocytes; Growth Disorders; Humans; Male; Mice; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Rats; Tumor Suppressor Protein p53; Ubiquitin; Up-Regulation

2007
Proteasome inhibition therapies in childhood cancer.
    Leukemia, 2008, Volume: 22, Issue:4

    Topics: Animals; Bone Development; Boronic Acids; Bortezomib; Child; Chondrocytes; Humans; Mice; Neoplasms; Protease Inhibitors; Pyrazines

2008
Potent anti-inflammatory effects of low-dose proteasome inhibition in the vascular system.
    Journal of molecular medicine (Berlin, Germany), 2009, Volume: 87, Issue:8

    Topics: Animals; Anti-Inflammatory Agents; Boronic Acids; Bortezomib; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Endothelial Cells; Enzyme Inhibitors; Gene Expression Regulation; Humans; Leupeptins; Male; Monocytes; NF-kappa B; Oxidative Stress; Proteasome Inhibitors; Pyrazines; Rats; Rats, Inbred Dahl; Reactive Oxygen Species; Tumor Necrosis Factor-alpha; Vascular Cell Adhesion Molecule-1

2009
Proteasome functional insufficiency activates the calcineurin-NFAT pathway in cardiomyocytes and promotes maladaptive remodelling of stressed mouse hearts.
    Cardiovascular research, 2010, Dec-01, Volume: 88, Issue:3

    Topics: Animals; Boronic Acids; Bortezomib; Calcineurin; Cells, Cultured; Desmin; Heart Failure; Mice; Mice, Transgenic; Models, Animal; Myocytes, Cardiac; NFATC Transcription Factors; Protease Inhibitors; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Signal Transduction; Stress, Physiological

2010