Page last updated: 2024-08-21

pyrazines and leptin

pyrazines has been researched along with leptin in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (10.00)18.2507
2000's5 (50.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Casanueva, FF; Considine, RV; Cordido, F; Dieguez, C; Fernández Alvarez, J; Peinò, R; Peñalva, A; Rodriguez-Garcia, J; Rodriguez-Segade, S1
Fritsche, A; Häring, H; Lehmann, R; Renn, W; Stumvoll, M; Tschritter, O; Wahl, HG1
Beck-Nielsen, H; Henriksen, JE; Vaag, A; Vinten, J; Worm, D1
Guo, W; Han, J; Wang-Fisher, YL1
Christiansen, JS; Hansen, TK; Jorgensen, JO; Moller, N; Nielsen, S; Vestergaard, ET1
Bae, EJ; Kim, JW; Kim, SG; Yang, YM1
Li, S; Lu, B; Si, S; Yu, L; Zeng, Y1
Cao, HJ; Hu, HJ; Li, SG; Liu, J; Lv, B; Zhong, JH; Zhou, J; Zhu, L1
Sekhar, RV1
Konishi, H; Kyohara, M; Okuyama, T; Shirakawa, J; Tajima, K; Terauchi, Y; Togashi, Y; Yamazaki, S1

Reviews

1 review(s) available for pyrazines and leptin

ArticleYear
Treatment of dyslipidemia in HIV.
    Current atherosclerosis reports, 2015, Volume: 17, Issue:4

    Topics: Anti-HIV Agents; Anticholesteremic Agents; Azetidines; Cholesterol, HDL; Cholesterol, LDL; Diet Therapy; Dyslipidemias; Exercise Therapy; Ezetimibe; Fatty Acids, Nonesterified; Fatty Acids, Omega-3; Fibric Acids; Glutathione; Growth Hormone-Releasing Hormone; HIV Infections; Human Growth Hormone; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Leptin; Niacin; Pyrazines; Thiazolidinediones; Triglycerides

2015

Trials

3 trial(s) available for pyrazines and leptin

ArticleYear
Acute changes in free-fatty acids (FFA) do not alter serum leptin levels.
    Journal of endocrinological investigation, 1998, Volume: 21, Issue:8

    Topics: Adult; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Heparin; Humans; Hypolipidemic Agents; Kinetics; Leptin; Male; Obesity; Placebos; Proteins; Pyrazines

1998
The nicotinic acid analogue acipimox increases plasma leptin and decreases free fatty acids in type 2 diabetic patients.
    European journal of endocrinology, 2000, Volume: 143, Issue:3

    Topics: Area Under Curve; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Fatty Acids, Nonesterified; Female; Humans; Hypolipidemic Agents; Insulin; Leptin; Male; Middle Aged; Niacin; Pyrazines; Triglycerides

2000
Effects of GH replacement therapy in adults on serum levels of leptin and ghrelin: the role of lipolysis.
    European journal of endocrinology, 2005, Volume: 153, Issue:4

    Topics: Adult; Drug Combinations; Fasting; Fatty Acids, Nonesterified; Female; Ghrelin; Growth Hormone; Hormone Replacement Therapy; Human Growth Hormone; Humans; Hypolipidemic Agents; Insulin Resistance; Leptin; Lipolysis; Male; Middle Aged; Peptide Hormones; Pyrazines; Steroid Metabolism, Inborn Errors; Sterol Esterase

2005

Other Studies

6 other study(ies) available for pyrazines and leptin

ArticleYear
Leptin levels in humans are acutely suppressed by isoproterenol despite acipimox-induced inhibition of lipolysis, but not by free fatty acids.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:3

    Topics: Adult; Blood Glucose; Fat Emulsions, Intravenous; Fatty Acids, Nonesterified; Female; Heparin; Humans; Hypolipidemic Agents; Insulin; Isoproterenol; Leptin; Lipolysis; Male; Pyrazines; Reference Values; Time Factors

2000
Acipimox stimulates leptin production from isolated rat adipocytes.
    The Journal of endocrinology, 2002, Volume: 174, Issue:2

    Topics: Adipocytes; Animals; Bucladesine; Cells, Cultured; Female; Glycerol; Hypolipidemic Agents; Insulin; Leptin; Lipolysis; Niacin; Norepinephrine; Pyrazines; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

2002
Identification of a novel class of dithiolethiones that prevent hepatic insulin resistance via the adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway.
    Hepatology (Baltimore, Md.), 2007, Volume: 46, Issue:3

    Topics: AMP-Activated Protein Kinases; Animals; Cell Line; Glucose; Hypoglycemia; Insulin; Insulin Resistance; Leptin; Liver; Mice; Mice, Mutant Strains; Multienzyme Complexes; Phosphorylation; Protein Serine-Threonine Kinases; Pyrazines; Ribosomal Protein S6 Kinases, 70-kDa; Thiones; Thiophenes; Transfection; Transforming Growth Factor alpha

2007
Alleviation of CCl4-induced cirrhosis in rats by tetramethylpyrazine is associated with downregulation of leptin and TGF-beta1 pathway.
    Drug and chemical toxicology, 2010, Volume: 33, Issue:3

    Topics: Animals; Blotting, Western; Carbon Tetrachloride; Down-Regulation; Fibrinolytic Agents; Histocytochemistry; Leptin; Liver Cirrhosis; Male; Pyrazines; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Leptin; Receptors, Transforming Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Smad3 Protein; Smad7 Protein; Transforming Growth Factor beta1

2010
Effects of miR-9 and tetramethylpyrazine on activation of hepatic stellate cells.
    Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:3

    Topics: Actins; Collagen Type I; Gene Expression Regulation; Hepatic Stellate Cells; Humans; Janus Kinase 1; Leptin; Ligusticum; Liver Cirrhosis; MicroRNAs; Phosphorylation; Phytotherapy; Plant Extracts; Pyrazines; Real-Time Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Transfection; Up-Regulation

2015
Metabolic recovery of lipodystrophy, liver steatosis, and pancreatic β cell proliferation after the withdrawal of OSI-906.
    Scientific reports, 2017, 06-23, Volume: 7, Issue:1

    Topics: Animals; Cell Proliferation; Dietary Supplements; Energy Metabolism; Fatty Liver; Hyperglycemia; Hyperinsulinism; Hyperlipidemias; Imidazoles; Insulin-Secreting Cells; Leptin; Lipodystrophy; Mice; Pyrazines; Safety-Based Drug Withdrawals; Time Factors; Tomography, X-Ray Computed

2017