Compounds > pyrazines
Page last updated: 2024-08-21

pyrazines and ku 55933

pyrazines has been researched along with ku 55933 in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Durišová, K; Lukášová, E; Novotná, E; Pejchal, J; Řezáčová, M; Sinkorová, Z; Tichý, A; Vávrová, J; Zárybnická, L1
Ali, S; Buluwela, L; Farzan, R; Meek, DW; Saurin, AT; Smith, L1
Freire, R; Kim, D; Liu, Y; Oberly, S; Smolka, MB1
da Silva, RB; Machado, CR; Pedrosa, AL; Rodrigues, ARA1
Badura, J; Becker, H; Fahrer, J; Heylmann, D; Kaina, B1
Moolmuang, B; Ruchirawat, M1
Gondhowiardjo, S; Gu, W; Kakoti, S; Kato, R; Ohno, T; Oike, T; Permata, TBM; Sato, H; Sato, I; Shibata, A; Suzuki, K; Tsushima, Y; Uchihara, Y; Yamauchi, M; Yasuhara, T; Yoshimatsu, Y1

Other Studies

7 other study(ies) available for pyrazines and ku 55933

ArticleYear
Inhibition of ATR kinase with the selective inhibitor VE-821 results in radiosensitization of cells of promyelocytic leukaemia (HL-60).
    Radiation and environmental biophysics, 2013, Volume: 52, Issue:4

    Topics: Apoptosis; Ataxia Telangiectasia Mutated Proteins; DNA Repair; G2 Phase Cell Cycle Checkpoints; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; Morpholines; Protein Kinase Inhibitors; Pyrazines; Pyrones; Radiation Tolerance; Sulfones

2013
The responses of cancer cells to PLK1 inhibitors reveal a novel protective role for p53 in maintaining centrosome separation.
    Scientific reports, 2017, 11-23, Volume: 7, Issue:1

    Topics: Benzimidazoles; Cell Cycle Proteins; Cell Survival; Centrosome; Fluorescent Antibody Technique; Gene Silencing; HCT116 Cells; Humans; Mitosis; Morpholines; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyrazines; Pyrones; Sulfones; Thiophenes; Tumor Suppressor Protein p53

2017
ATR-mediated proteome remodeling is a major determinant of homologous recombination capacity in cancer cells.
    Nucleic acids research, 2018, 09-19, Volume: 46, Issue:16

    Topics: Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Cell Cycle; Cell Line, Tumor; Checkpoint Kinase 1; Humans; Morpholines; Neoplasm Proteins; Poly(ADP-ribose) Polymerase Inhibitors; Protein Stability; Proteome; Pyrazines; Pyrones; Recombinational DNA Repair; Signal Transduction; Sulfones; Transcription, Genetic

2018
Selective human inhibitors of ATR and ATM render Leishmania major promastigotes sensitive to oxidative damage.
    PloS one, 2018, Volume: 13, Issue:9

    Topics: Ataxia Telangiectasia Mutated Proteins; Humans; Leishmania major; Life Cycle Stages; Morpholines; Oxidative Stress; Pyrazines; Pyrones; Signal Transduction; Sulfones

2018
Sensitivity of CD3/CD28-stimulated versus non-stimulated lymphocytes to ionizing radiation and genotoxic anticancer drugs: key role of ATM in the differential radiation response.
    Cell death & disease, 2018, 10-15, Volume: 9, Issue:11

    Topics: Amino Acid Chloromethyl Ketones; Antibodies; Ataxia Telangiectasia Mutated Proteins; Caspases; CD28 Antigens; CD3 Complex; Cell Proliferation; Chromones; DNA-Activated Protein Kinase; Drug Resistance; Gamma Rays; Gene Expression Regulation; Humans; Isoxazoles; Lymphocyte Activation; Morpholines; MRE11 Homologue Protein; Primary Cell Culture; Pyrazines; Pyrones; Radiation Tolerance; Signal Transduction; T-Lymphocytes, Cytotoxic; T-Lymphocytes, Regulatory; Thiophenes; Thioxanthenes

2018
The antiproliferative effects of ataxia-telangiectasia mutated and ATM- and Rad3-related inhibitions and their enhancements with the cytotoxicity of DNA damaging agents in cholangiocarcinoma cells.
    The Journal of pharmacy and pharmacology, 2021, Mar-01, Volume: 73, Issue:1

    Topics: Antineoplastic Agents; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; Bile Duct Neoplasms; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; DNA Damage; Humans; Morpholines; Protein Kinase Inhibitors; Pyrazines; Pyrones; Sulfones; Tumor Suppressor Protein p53

2021
High linear energy transfer carbon-ion irradiation upregulates PD-L1 expression more significantly than X-rays in human osteosarcoma U2OS cells.
    Journal of radiation research, 2021, Sep-13, Volume: 62, Issue:5

    Topics: Ataxia Telangiectasia Mutated Proteins; B7-H1 Antigen; Bone Neoplasms; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Heavy Ion Radiotherapy; Humans; Imaging, Three-Dimensional; Interferon Regulatory Factor-1; Linear Energy Transfer; Morpholines; Neoplasm Proteins; Osteosarcoma; Phosphorylation; Protein Processing, Post-Translational; Pyrazines; Pyrones; RNA, Messenger; RNA, Neoplasm; STAT1 Transcription Factor; Sulfones; Up-Regulation; X-Rays

2021