pyrazines has been researched along with kd 5170 in 1 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Feng, R; Hager, JH; Hassig, CA; Lentzsch, S; Ma, H; Mapara, MY; Payne, JE; Smith, ND | 1 |
1 other study(ies) available for pyrazines and kd 5170
Article | Year |
---|---|
KD5170, a novel mercaptoketone-based histone deacetylase inhibitor, exerts antimyeloma effects by DNA damage and mitochondrial signaling.
Topics: Acetylation; Animals; Antineoplastic Agents; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Boronic Acids; Bortezomib; Caspases; Cell Line, Tumor; DNA Damage; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; Enzyme Inhibitors; Histone Deacetylase Inhibitors; Histones; Humans; Ketones; Membrane Potential, Mitochondrial; Mice; Mitochondria; Multiple Myeloma; Oxidative Stress; Protein Transport; Pyrazines; Pyridines; Signal Transduction; Sulfonamides; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays | 2008 |