pyrazines has been researched along with k 7174 in 1 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Akutsu, M; Furukawa, Y; Izumi, T; Kano, Y; Kikuchi, J; Koyama, D; Nobuyoshi, M; Wada, T; Yamada, S | 1 |
1 trial(s) available for pyrazines and k 7174
Article | Year |
---|---|
The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.
Topics: Administration, Oral; Animals; Anisoles; Antineoplastic Agents; Azepines; Boronic Acids; Bortezomib; Cell Line, Tumor; Down-Regulation; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Multiple Myeloma; Pyrazines | 2013 |