pyrazines has been researched along with isoniazid in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (59.09) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Bowman, Z; Cooper, CM; Stanton, HC | 1 |
| Lucchesi, M; Mancini, P; Matzeu, M | 1 |
| Leiber, DL; Verhagen, AR | 1 |
| Freerksen, E; Rosenfeld, M | 1 |
| Blenska, W; Kolakowska, E | 1 |
| Verhagen, AR | 1 |
| Eule, H | 1 |
| Pavlov, EP; Soloviev, VN | 1 |
| Freerksen, E; Hokama, S; Rosenfeld, M | 1 |
| Görgényi-Göttche, O; Vass, E | 1 |
| Pasargiklian, M | 1 |
| Daddi, G | 1 |
| Corda, M | 1 |
| Heifets, L; Higgins, M; Simon, B | 1 |
| Bu, S; Kim, S; Kim, Y; Lee, M | 1 |
| Teyssier, L | 1 |
| Abrigo, C; Calvino, R; Gennaro, MC | 1 |
| Bae, SK; Kim, T; Kim, YH; Lee, MG; Lee, SJ | 1 |
| Baykam, N; Celikbaş, AK; Dokuzoguz, B; Eren, S; Ergönül, O; Ulu, A | 1 |
| Arshad, N; Khan, M; Mirza, B; Rashid, N; Razzque, S; Saleem, S; Yunus, U | 1 |
| Özkaya, E | 1 |
| Bi, J; Chan, CK; Chen, S; Cui, Y; Guo, Q; Hu, S; Kaneko, T; Pan, M; Wang, H; Xiao, G; Yuan, Y; Zhang, G; Zhang, Y | 1 |
1 review(s) available for pyrazines and isoniazid
| Article | Year |
|---|---|
[Current status of chemotherapy of pulmonary tuberculosis and its further prospectives].
Topics: Aminosalicylic Acids; Antitubercular Agents; Chemical and Drug Induced Liver Injury; Cycloserine; Drug Resistance, Microbial; Drug Synergism; Drug Tolerance; Hemorrhagic Disorders; Humans; Isoniazid; Kanamycin; Phenylthiourea; Purpura, Thrombocytopenic; Pyrazines; Recurrence; Rifampin; Streptomycin; Tuberculosis, Pulmonary | 1971 |
1 trial(s) available for pyrazines and isoniazid
| Article | Year |
|---|---|
[On therapeutic effects of morphazinamide, used alone and in association, in recent and chronic pulmonary tuberculosis].
Topics: Antitubercular Agents; Clinical Trials as Topic; Cycloserine; Humans; Isoniazid; Pyrazines; Tuberculosis, Pulmonary | 1965 |
20 other study(ies) available for pyrazines and isoniazid
| Article | Year |
|---|---|
Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in rats.
Topics: Animals; Carbon Isotopes; Cardiomegaly; DNA; Female; Glycine; Isocarboxazid; Isoniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardium; Nialamide; Nucleic Acids; Pargyline; Phenelzine; Piperidines; Pyrazines; Rats; RNA; Tranylcypromine | 1970 |
[Drug sensitivity of the so-called atypical mycobacteria].
Topics: Aminosalicylic Acids; Antitubercular Agents; Cycloserine; Drug Resistance, Microbial; Ethambutol; Ethionamide; In Vitro Techniques; Isoniazid; Kanamycin; Microbial Sensitivity Tests; Morpholines; Mycobacterium; Pyrazinamide; Pyrazines; Rifampin; Streptomycin; Viomycin | 1968 |
Assessment of the bacteriological effect of combined treatment with rifadin, sulfamethoxypyrazine, and isoniazide in lepromatous leprosy.
Topics: Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Microbial Sensitivity Tests; Muscle, Smooth; Mycobacterium leprae; Pyrazines; Rifampin; Skin; Sulfanilamides; Time Factors | 1973 |
A new analogous model for the detection and evaluation of chemotherapeutic products effective in leprosy.
Topics: Aniline Compounds; Animals; Dapsone; Disease Models, Animal; Drug Combinations; Ethionamide; Humans; Isoniazid; Leprosy; Mice; Models, Biological; Mycobacterium Infections; Phenazines; Pyrazines; Rabbits; Rifampin; Sulfonamides; Trimethoprim | 1972 |
A pilot study of leprosy treatment with a combination of various antileprosy drugs. Preliminary report.
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Humans; Isoniazid; Leprosy; Male; Pilot Projects; Pyrazines; Rifampin; Sulfanilamides; Sulfonamides; Time Factors; Trimethoprim; Uganda | 1973 |
[Administration of a new antimycobacterial combined therapy in leprosy in East Africa].
Topics: Africa, Eastern; Antitubercular Agents; Dapsone; Drug Therapy, Combination; Female; Humans; Isoniazid; Leprosy; Male; Prognosis; Pyrazines; Rifampin; Sulfanilamides; Time Factors | 1973 |
Significance of intracellular medium for antimycobacterial activity of some pyrazin-2-carbonic acid derivatives.
Topics: Animals; Antitubercular Agents; Culture Media; Culture Techniques; Hydrogen-Ion Concentration; Isoniazid; Mice; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines | 1966 |
Systemic chemotherapy in mice experimentally infected with Mycobacterium marinum.
Topics: Administration, Oral; Animals; Dapsone; Demeclocycline; Ethionamide; Female; Isoniazid; Mice; Mice, Inbred Strains; Mycobacterium Infections; Phenylthiourea; Pyrazines; Rifampin; Sulfonamides | 1971 |
[Treatment of tuberculosis of children in the age of puberty (isoniazid and morfazinamide)].
Topics: Adolescent; Antitubercular Agents; Child; Child, Preschool; Female; Humans; Isoniazid; Male; Morpholines; Pyrazines; Streptomycin; Thiosemicarbazones; Tuberculosis, Pulmonary | 1968 |
[Experience with te new antitubercular agents isoxyl, ethambutol, morphazinamid and rifomycin].
Topics: Culture Techniques; Cycloserine; Ethambutol; Humans; Isoniazid; Monocytes; Phenylthiourea; Pyrazines; Rifampin; Tuberculosis, Pulmonary | 1967 |
[Problems of post-sanatorial antimycobacterial treatment].
Topics: Antitubercular Agents; Cycloserine; Ethionamide; Follow-Up Studies; Humans; Isoniazid; Pyrazines; Tuberculosis, Pulmonary | 1965 |
Pyrazinamide is not active against Mycobacterium tuberculosis residing in cultured human monocyte-derived macrophages.
Topics: Antitubercular Agents; Cells, Cultured; Humans; Isoniazid; Macrophages; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines | 2000 |
Effects of enzyme inducers and inhibitor on the pharmacokinetics of intravenous 2-(allylthio)pyrazine, a new chemoprotective agent, in rats.
Topics: Amines; Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Drug Interactions; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Phenobarbital; Proadifen; Pyrazines; Rats; Rats, Sprague-Dawley | 2000 |
Higher activity of morphazinamide over pyrazinamide against intracellular.
Topics: Antitubercular Agents; Humans; Isoniazid; Macrophages; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrazinamide; Pyrazines; Sensitivity and Specificity | 2001 |
Ion interaction reagent reversed-phase high-performance liquid chromatography determination of anti-tuberculosis drugs and metabolites in biological fluids.
Topics: Aminosalicylic Acid; Animals; Antitubercular Agents; Calibration; Chromatography, High Pressure Liquid; Ethionamide; Humans; Isoniazid; Isonicotinic Acids; Niacin; Pyrazinamide; Pyrazines; Quality Control; Rats | 2001 |
Effect of enzyme inducers and inhibitors on the pharmacokinetics of oltipraz in rats.
Topics: Animals; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Enzyme Inhibitors; Isoenzymes; Isoniazid; Male; Metabolic Clearance Rate; Methylcholanthrene; Microsomes, Liver; Models, Animal; Phenobarbital; Pyrazines; Rats; Rats, Sprague-Dawley; Thiones; Thiophenes | 2005 |
[Case report: cutaneous tuberculosis and tuberculous osteomyelitis].
Topics: Adult; Antitubercular Agents; Drug Therapy, Combination; Humans; Immunocompetence; Isoniazid; Male; Osteomyelitis; Pyrazines; Rifampin; Tibia; Tomography, X-Ray Computed; Tuberculosis, Cutaneous; Tuberculosis, Osteoarticular | 2005 |
Electrochemical and spectroscopic investigations of isoniazide and its analogs with ds.DNA at physiological pH: evaluation of biological activities.
Topics: Animals; Anti-Bacterial Agents; Binding Sites; DNA; DNA Damage; Electrochemistry; Free Radical Scavengers; Hydrazines; Hydrogen-Ion Concentration; Hydroxyl Radical; Isoniazid; Oxidative Stress; Pyrazines; Spectrum Analysis; Temperature | 2012 |
Eczematous-type multiple drug allergy from isoniazid and ethambutol with positive patch test results.
Topics: Antitubercular Agents; Drug Eruptions; Drug Therapy, Combination; Eczema; Ethambutol; Follow-Up Studies; Humans; Isoniazid; Male; Middle Aged; Patch Tests; Pyrazines; Rifampin | 2013 |
Human Kinase IGF1R/IR Inhibitor Linsitinib Controls the In Vitro and Intracellular Growth of
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Glutamine; Humans; Imidazoles; Isoniazid; Lipids; Mycobacterium tuberculosis; Protein Kinase Inhibitors; Pyrazines; Receptor, IGF Type 1; TOR Serine-Threonine Kinases; Tuberculosis | 2022 |