Page last updated: 2024-08-21

pyrazines and hydrazine

pyrazines has been researched along with hydrazine in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19904 (14.81)18.7374
1990's1 (3.70)18.2507
2000's7 (25.93)29.6817
2010's15 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Foks, H; Janowiec, M2
Zinner, G1
Heinisch, G; Holzer, W; Kunz, F; Langer, T; Lukavsky, P; Pechlaner, C; Weissenberger, H1
SAIKACHI, H; TAGAMI, S1
Butini, S; Campiani, G; Chiasserini, L; Fattorusso, C; Gemma, S; Kukreja, G; Locatelli, GA; Maga, G; Nacci, V; Novellino, E; Persico, M; Romano, MP; Savini, L; Spadari, S1
Davis, M; Donovan, JL; Hamdy, FC; Lane, JA; Metcalfe, C; Mills, N; Neal, DE; Peters, TJ; Ronsmans, C; Sterne, JA1
Bayne, R; Bréchot, C; Christa, L; Cortes, A; Hunt, SP; Kebede, M; Lieu, HT; Nguyen-Khoa, T; Simon, MT; Smith, AJ; Tebar, L1
Funaki, T; Ichijo, N; Kon, S; Natsume, W; Satake, M; Tanabe, K; Watanabe, T1
Mao, H; Schnellmann, RG; Xing, J; Zhang, Z; Zhuang, S1
Birgens, H; Brown, Pde N; Dalseg, AM; Dufva, IH; Hasselbalch, HC; Jensen, MK; Vangsted, A1
Chaintreau, A; Egger, J; Rochat, S1
Hata, K; Ikeda, F; Matsubara, T; Nakanishi, M; Nishimura, R; Okada, M; Yasuda, H; Yoneda, T1
Abdel-Aziz, M; Abdel-Rahman, HM1
Borrelli, G; Brindisi, M; Butini, S; Campiani, G; Fiorini, I; Gemma, S; Maga, G; Novellino, E; Romano, MP; Savini, L; Tripaldi, P; Zanoli, S1
Gupta, AK; Gupta, RA; Kaskhedikar, SG; Soni, LK1
Bezerra, FA; Candéa, AL; de Souza, MV; Ferreira, ML; Henriques, MG; Kaiser, CR; Lima, CH; Lourenço, MC1
Foks, H; Gobis, K; Gołka, J; Główka, ML; Olczak, A; Szczesio, M1
Arshad, N; Khan, M; Mirza, B; Rashid, N; Razzque, S; Saleem, S; Yunus, U1
Foks, H; Gobis, K; Główka, ML; Olczak, A; Szczesio, M1
Ahmad, M; Aslam, S; Detorio, M; Montero, C; Parvez, M; Schinazi, RF; Zia-Ur-Rehman, M1
Aravinda, S; Gupta, VK; Kant, R; Rai, R; Wani, NA1
Karapetian, R; Krasavin, M; Lakontseva, E1
Baloglu, E; Cao, Q; Chu, P; Doan, N; Forscher, C; Gery, S; Guo, X; Koeffler, HP; Lee, VK; Lim, HJ; Lin, DC; Marijon, H; Mayakonda, A; Pang, B; Rajalingam, R; Said, JW; Shacham, S; Sun, H; Thomas, T; Xu, L; Yang, H; Zhao, Z1
Ahmad, M; Anwar, M; Din, G; Hameed, S; Israr, M; Khan, SA; Shah, MA; Tahir, MN1
Dömling, A; Kalinowska-Tluscik, J; Kurpiewska, K; Patil, P; Wang, Y1
Estey, EH; Percival, MM1

Reviews

2 review(s) available for pyrazines and hydrazine

ArticleYear
[Novel medical treatment modalities in hematology].
    Ugeskrift for laeger, 2008, Jun-09, Volume: 170, Issue:24

    Topics: Aminoglycosides; Anemia, Hemolytic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Agents; Benzamides; Benzoates; Boronic Acids; Bortezomib; Carbazoles; Carrier Proteins; Cyclophosphamide; Dasatinib; Furans; Gemtuzumab; Hematologic Diseases; Humans; Hydrazines; Imatinib Mesylate; Immunologic Factors; Indoles; Lenalidomide; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Lymphoma; Multiple Myeloma; Myelodysplastic Syndromes; Piperazines; Purpura, Thrombocytopenic; Pyrazines; Pyrazoles; Pyrimidines; Receptors, Fc; Recombinant Fusion Proteins; Rituximab; Thalidomide; Thiazoles; Thrombopoietin; Vidarabine

2008
Current treatment strategies for measurable residual disease in patients with acute myeloid leukemia.
    Cancer, 2019, Sep-15, Volume: 125, Issue:18

    Topics: Aminopyridines; Aniline Compounds; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Immunological; Azacitidine; Cytogenetic Analysis; Decitabine; Enzyme Inhibitors; Flow Cytometry; Hematopoietic Stem Cell Transplantation; Humans; Hydrazines; Immunologic Factors; In Situ Hybridization, Fluorescence; Lenalidomide; Leukemia, Myeloid, Acute; Molecular Diagnostic Techniques; Neoplasm, Residual; Nivolumab; para-Aminobenzoates; Protein Kinase Inhibitors; Pyrazines; Pyrrolidines; Recombinant Fusion Proteins; Remission Induction; Transplantation, Homologous; Triazines; Triazoles

2019

Other Studies

25 other study(ies) available for pyrazines and hydrazine

ArticleYear
[Studies on pyrazine derivatives. XIV. Synthesis and the tuberculostatic effect of pyrazinoamidrazones].
    Acta poloniae pharmaceutica, 1979, Volume: 36, Issue:2

    Topics: Antitubercular Agents; Chemical Phenomena; Chemistry; Hydrazines; In Vitro Techniques; Mycobacterium tuberculosis; Pyrazines

1979
[Condensation of pyrazinehydrazide and its 4-N-oxide with phenylglyoxalic acids].
    Acta poloniae pharmaceutica, 1977, Volume: 34, Issue:6

    Topics: Antitubercular Agents; Chemical Phenomena; Chemistry; Cyclic N-Oxides; Glyoxylates; Hydrazines; Pyrazines

1977
[On the Michael type addition of cyclic hydrazides to activated vinyl groups].
    Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1966, Volume: 299, Issue:4

    Topics: Chemical Phenomena; Chemistry; Hydrazines; Pyrazines; Pyrazoles; Triazoles

1966
On the bioisosteric potential of diazines: diazine analogues of the combined thromboxane A2 receptor antagonist and synthetase inhibitor Ridogrel.
    Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20

    Topics: Blood Platelets; Bridged Bicyclo Compounds, Heterocyclic; Collagen; Enzyme Inhibitors; Fatty Acids, Unsaturated; Humans; Hydrazines; Molecular Structure; Pentanoic Acids; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazines; Pyridazines; Pyridines; Pyrimidines; Receptors, Thromboxane; Structure-Activity Relationship; Thromboxane-A Synthase; Tritium

1996
[Studies on compounds related to pyrazine. IV. The reaction of 3-substituted 2-hydrazinoquinoxalines with carbonyl compounds. (2)].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1962, Volume: 82

    Topics: Heterocyclic Compounds; Hydrazines; Organic Chemicals; Pyrazines

1962
Specific targeting of hepatitis C virus NS3 RNA helicase. Discovery of the potent and selective competitive nucleotide-mimicking inhibitor QU663.
    Biochemistry, 2005, Jul-19, Volume: 44, Issue:28

    Topics: Adenosine Triphosphate; Antiviral Agents; Binding Sites; Binding, Competitive; DNA, Viral; Enzyme Inhibitors; Hepacivirus; Hydrazines; Hydrolysis; Molecular Mimicry; Pyrazines; Quinolines; Quinoxalines; RNA Helicases; Substrate Specificity; Viral Nonstructural Proteins

2005
A comparison of socio-demographic and psychological factors between patients consenting to randomisation and those selecting treatment (the ProtecT study).
    Contemporary clinical trials, 2006, Volume: 27, Issue:5

    Topics: Aged; Anxiety; Depression; Follow-Up Studies; Humans; Hydrazines; Male; Middle Aged; Patient Satisfaction; Patient Selection; Prostatic Neoplasms; Pyrazines; Quinolines; Randomized Controlled Trials as Topic; Socioeconomic Factors

2006
Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Chemical and Drug Induced Liver Injury; DNA; Extracellular Signal-Regulated MAP Kinases; fas Receptor; Hepatectomy; Humans; Hydrazines; Interleukin-6; Lectins, C-Type; Liver Regeneration; Mice; Mice, Transgenic; Oncogene Protein v-akt; Pancreatitis-Associated Proteins; Proteins; Pyrazines; Quinolines; Signal Transduction; Tumor Necrosis Factor-alpha

2006
A SMAP gene family encoding ARF GTPase-activating proteins and its implication in membrane trafficking.
    Methods in enzymology, 2008, Volume: 438

    Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Cadherins; Chlorocebus aethiops; COS Cells; GTPase-Activating Proteins; Humans; Hydrazines; Interleukin-2 Receptor alpha Subunit; Membrane Glycoproteins; Membrane Proteins; Mice; Molecular Sequence Data; Protein Transport; Pyrazines; Quinolines; Sequence Alignment; Small Ubiquitin-Related Modifier Proteins; Transferrin; Two-Hybrid System Techniques

2008
Src regulates cell cycle protein expression and renal epithelial cell proliferation via PI3K/Akt signaling-dependent and -independent mechanisms.
    American journal of physiology. Renal physiology, 2008, Volume: 295, Issue:1

    Topics: Cell Line; Cell Proliferation; Chromones; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinase Inhibitor p57; Epithelial Cells; Hydrazines; Kidney; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Morpholines; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Pyrazines; Quinolines; Signal Transduction; src-Family Kinases; Up-Regulation

2008
Strategy for the identification of key odorants: application to shrimp aroma.
    Journal of chromatography. A, 2009, Sep-04, Volume: 1216, Issue:36

    Topics: Analytic Sample Preparation Methods; Animals; Atlantic Ocean; Databases, Factual; Gas Chromatography-Mass Spectrometry; Head; Humans; Hydrazines; Indicators and Reagents; Methylamines; Molecular Structure; Odorants; Pandalidae; Polymers; Pyrazines; Pyrroles; Shellfish; Software; Volatilization

2009
Cbp recruitment of Csk into lipid rafts is critical to c-Src kinase activity and bone resorption in osteoclasts.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010, Volume: 25, Issue:5

    Topics: Actins; Animals; Apoptosis; Bone Resorption; Cell Differentiation; Cell Line; CSK Tyrosine-Protein Kinase; Hydrazines; Macrophages; Membrane Microdomains; Membrane Proteins; Mice; Osteoclasts; Phosphoproteins; Protein-Tyrosine Kinases; Pyrazines; Quinolines; Signal Transduction; src-Family Kinases

2010
Synthesis and anti-mycobacterial evaluation of some pyrazine-2-carboxylic acid hydrazide derivatives.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Chlorocebus aethiops; Hydrazines; Mycobacterium tuberculosis; Pyrazines; Structure-Activity Relationship; Vero Cells

2010
Discovery of potent nucleotide-mimicking competitive inhibitors of hepatitis C virus NS3 helicase.
    Bioorganic & medicinal chemistry letters, 2011, May-01, Volume: 21, Issue:9

    Topics: Binding, Competitive; Drug Discovery; Hepacivirus; Hydrazines; Protein Binding; Pyrazines; Quinolines; Viral Nonstructural Proteins

2011
2-(pyrazin-2-yloxy)acetohydrazide analogs QSAR Study: An insight into the structural basis of antimycobacterial activity.
    Chemical biology & drug design, 2010, Volume: 76, Issue:5

    Topics: Anti-Bacterial Agents; Antitubercular Agents; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Pyrazines; Quantitative Structure-Activity Relationship; Thermodynamics

2010
Synthesis and antimycobacterial evaluation of N'-(E)-heteroaromaticpyrazine-2-carbohydrazide derivatives.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2011, Volume: 7, Issue:3

    Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Hydrazines; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrazines; Stereoisomerism

2011
Planarity of heteroaryldithiocarbazic acid derivatives showing tuberculostatic activity. III. Mono- and diesters of 3-(pyrazin-2-ylcarbonyl)dithiocarbazic acid.
    Acta crystallographica. Section C, Crystal structure communications, 2011, Volume: 67, Issue:Pt 7

    Topics: Antitubercular Agents; Crystallography, X-Ray; Hydrazines; Hydrogen Bonding; Molecular Structure; Mycobacterium tuberculosis; Pyrazines

2011
Electrochemical and spectroscopic investigations of isoniazide and its analogs with ds.DNA at physiological pH: evaluation of biological activities.
    European journal of medicinal chemistry, 2012, Volume: 47, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Binding Sites; DNA; DNA Damage; Electrochemistry; Free Radical Scavengers; Hydrazines; Hydrogen-Ion Concentration; Hydroxyl Radical; Isoniazid; Oxidative Stress; Pyrazines; Spectrum Analysis; Temperature

2012
Planarity of heteroaryldithiocarbazic acid derivatives showing tuberculostatic activity. IV. Diesters of benzoylcarbonohydrazonodithioic acid.
    Acta crystallographica. Section C, Crystal structure communications, 2012, Volume: 68, Issue:Pt 3

    Topics: Antitubercular Agents; Crystallography, X-Ray; Esters; Hydrazines; Hydrogen Bonding; Molecular Structure; Mycobacterium tuberculosis; Pyrazines

2012
Synthesis and anti-HIV-1 screening of novel N'-(1-(aryl)ethylidene)-2-(5,5-dioxido-3-phenylbenzo[e]pyrazolo[4,3-c][1,2]thiazin-4(1H)-yl)acetohydrazides.
    Archives of pharmacal research, 2014, Volume: 37, Issue:11

    Topics: Animals; Anti-HIV Agents; Chlorocebus aethiops; Crystallography, X-Ray; HIV-1; Humans; Hydrazines; Leukocytes, Mononuclear; Molecular Structure; Pyrazines; Thiazines; Vero Cells; Virus Replication

2014
An unusual conformation of gabapentin (Gpn) in Pyr-Gpn-NH-NH-Pyr stabilized by weak interactions.
    Acta crystallographica. Section C, Structural chemistry, 2014, Volume: 70, Issue:Pt 8

    Topics: Amines; Crystallography, X-Ray; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobutyric Acid; Hydrazines; Hydrogen Bonding; Molecular Conformation; Molecular Structure; Pyrazines; Stereoisomerism

2014
New Antimycobacterial Leads from Multicomponent Hydrazino-Ugi Reaction.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2016, Volume: 12, Issue:2

    Topics: Animals; Antitubercular Agents; HEK293 Cells; Humans; Hydrazines; Hydrolysis; Isonicotinic Acids; Mycobacterium tuberculosis; Pyrazines; Rats, Sprague-Dawley; Structure-Activity Relationship

2016
CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1-Dependent IGF-1 Signaling.
    Cancer research, 2016, 05-01, Volume: 76, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Survival; Drug Synergism; Exportin 1 Protein; Female; Gene Knockdown Techniques; Humans; Hydrazines; Imidazoles; Immunoblotting; Immunohistochemistry; Insulin-Like Growth Factor I; Karyopherins; Mice; Mice, Nude; Oncogene Proteins, Fusion; Proto-Oncogene Protein c-fli-1; Pyrazines; Real-Time Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; RNA-Binding Protein EWS; Sarcoma, Ewing; Signal Transduction; Triazoles; Xenograft Model Antitumor Assays

2016
Synthesis, characterization and biological evaluation of some 5-methylpyrazine carbohydrazide based hydrazones.
    Pakistan journal of pharmaceutical sciences, 2016, Volume: 29, Issue:3

    Topics: Anti-Infective Agents; Antioxidants; Carbon-13 Magnetic Resonance Spectroscopy; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Hydrazines; Hydrazones; Mass Spectrometry; Models, Molecular; Molecular Structure; Proton Magnetic Resonance Spectroscopy; Pyrazines; Spectrophotometry, Infrared; Structure-Activity Relationship; Urease

2016
Two Cycles with One Catch: Hydrazine in Ugi 4-CR and Its Postcyclizations.
    ACS combinatorial science, 2017, 03-13, Volume: 19, Issue:3

    Topics: Combinatorial Chemistry Techniques; Cyanides; Cyclization; Hydrazines; Models, Molecular; Pyrazines; Tetrazoles

2017