Compounds > pyrazines
Page last updated: 2024-08-21

pyrazines and hbx 41108

pyrazines has been researched along with hbx 41108 in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aushev, VN; Bianchi, J; Boissy, G; Borg-Capra, C; Calabrese, A; Camonis, J; Colland, F; Collura, V; Conrath, S; Daviet, L; Delansorne, R; Formstecher, E; Guedat, P; Jacq, X; Planquette, C; Rain, JC; Reverdy, C; Sippl, W; Trouplin, V1
Nicholson, B; Suresh Kumar, KG1
Ahn, BY; Baek, KH; Cho, JG; Chung, SS; Kang, AY; Kim, CM; Kim, M; Lee, KW; Lim, KH; Park, KS; Park, SG; Sung, JH1
Ge, W; Jiang, Y; Li, W; Lv, L; Tang, Y; Zhang, X; Zhou, Y1
Dobner, T; Heim, A; Kosulin, K; Lam, E; Rodríguez, E1
Gu, W; Sun, H; Tavana, O1

Reviews

1 review(s) available for pyrazines and hbx 41108

ArticleYear
The multifaceted roles of USP7: new therapeutic opportunities.
    Cell biochemistry and biophysics, 2011, Volume: 60, Issue:1-2

    Topics: Apoptosis; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Indenes; Protease Inhibitors; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitin-Specific Peptidase 7

2011

Other Studies

5 other study(ies) available for pyrazines and hbx 41108

ArticleYear
Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:8

    Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Indenes; Protease Inhibitors; Pyrazines; Tumor Suppressor Protein p53; Ubiquitin Thiolesterase; Ubiquitin-Specific Peptidase 7

2009
Herpesvirus-associated ubiquitin-specific protease (HAUSP) modulates peroxisome proliferator-activated receptor γ (PPARγ) stability through its deubiquitinating activity.
    The Journal of biological chemistry, 2013, Nov-15, Volume: 288, Issue:46

    Topics: Adenoviridae; Amino Acid Substitution; Animals; Biological Transport, Active; Blood Glucose; Chlorocebus aethiops; COS Cells; Fatty Acids; Gene Knockdown Techniques; HeLa Cells; Hep G2 Cells; Humans; Indenes; Male; Mice; Mutagenesis, Site-Directed; Mutation, Missense; PPAR gamma; Protein Stability; Pyrazines; Transcription, Genetic; Transduction, Genetic; Ubiquitin Thiolesterase; Ubiquitin-Specific Peptidase 7; Ubiquitin-Specific Proteases; Ubiquitination

2013
Protein deubiquitinase USP7 is required for osteogenic differentiation of human adipose-derived stem cells.
    Stem cell research & therapy, 2017, 08-14, Volume: 8, Issue:1

    Topics: Adipogenesis; Adipose Tissue; Cell Differentiation; Gene Knockdown Techniques; Humans; Indenes; Mesenchymal Stem Cells; Osteogenesis; Pyrazines; Stem Cells; Ubiquitin-Specific Peptidase 7

2017
Broad-spectrum antiviral activity of the deubiquitinase inhibitor HBX against human adenoviruses
    Antiviral therapy, 2018, Volume: 23, Issue:6

    Topics: A549 Cells; Adenoviruses, Human; Antiviral Agents; Enzyme Inhibitors; Gene Expression Regulation; Genome, Viral; Host-Pathogen Interactions; Humans; Indenes; Inhibitory Concentration 50; Pyrazines; Signal Transduction; Ubiquitin-Specific Peptidase 7; Viral Load; Virion; Virus Replication

2018
Targeting HAUSP in both p53 wildtype and p53-mutant tumors.
    Cell cycle (Georgetown, Tex.), 2018, Volume: 17, Issue:7

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; HCT116 Cells; Humans; Imidazoles; Indenes; Molecular Targeted Therapy; N-Myc Proto-Oncogene Protein; Neurons; Piperazines; Protease Inhibitors; Protein Stability; Proto-Oncogene Proteins c-mdm2; Pyrazines; RNA, Small Interfering; Signal Transduction; Thiophenes; Tumor Suppressor Protein p53; Ubiquitin-Specific Peptidase 7

2018