Page last updated: 2024-08-21

pyrazines and glycine

pyrazines has been researched along with glycine in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.16)18.7374
1990's3 (6.12)18.2507
2000's13 (26.53)29.6817
2010's22 (44.90)24.3611
2020's7 (14.29)2.80

Authors

AuthorsStudies
Bowman, Z; Cooper, CM; Stanton, HC1
von Bruchhausen, F1
Devik, OG; Kadar, R1
Dorman, DE; Engel, GL; Indelicato, JM1
Cugola, A; Donati, D; Micheli, F; Missio, A; Pecunioso, A; Reggiani, A; Tarzia, G1
Hiramoto, K; Ishihara, T; Kato, T; Kikugawa, K; Maeda, Y; Takada, C; Tanaka, M1
Boireau, A; Chevé, M; Damour, D; Genevois-Borella, A; Imperato, A; Jimonet, P; Mignani, S; Pratt, J; Randle, JC; Ribeill, Y; Stutzmann, JM1
Hiramoto, K; Kato, T; Kikugawa, K; Yanagawa, H1
Brady, CS; FitzGerald, MX; Mackarel, AJ; O'Connor, CM; Russell, KJ1
Boireau, A; Bordier, F; Imperato, A; Meunier, M; Monterrat, C1
Avendaño, C; Corzo-Suárez, R; Espada, M; Gago, F; García-Granda, S; Martín-Santamaría, S; Rzepa, HS1
Adams, A; De Kimpe, N; Kersiene, M; Tehrani, KA; Venskutonis, R1
Burkoth, TS; Charych, DH; Connolly, MD; Fafarman, AT; Zuckermann, RN1
Kashman, Y; Lang, S; Pappo, D; Vartanian, M1
Haffenden, LJ; Yaylayan, VA1
Heinzl, S1
Amano, S; Ehama, R; Matsunaga, Y; Nishiyama, T; Ogura, Y; Tagami, H1
Noda, Y; Peterson, DG1
Low, MY; Mottram, DS; Parker, JK1
Haldoupis, Y; Koutsidis, G; Mojica-Lazaro, J; Mottram, DS; Simons, SP; Thong, YH; Wedzicha, BL1
Bannerman, B; Berger, A; Blank, J; Bolen, J; Bruzzese, F; Cao, Y; Dick, L; Fitzgerald, M; Fleming, P; Garcia, K; Hales, P; Kupperman, E; Lee, EC; Liu, J; Manfredi, M; Rolfe, M; Tsu, C; Yang, Y; Yu, J; Yu, L1
Dickschat, JS; Kunze, B; Nawrath, T; Schulz, S1
Guerra, PV; Yaylayan, VA2
Belmonte, C; Morenilla-Palao, C; Valero, M; Viana, F1
Anderson, KC; Chauhan, D; Kuhn, D; Orlowski, R; Raje, N; Richardson, P; Tian, Z; Zhou, B1
Bannerman, B; Bano, K; Berger, AJ; Bolen, JB; Bradley, DP; Carsillo, M; Donelan, J; Fitzgerald, M; Hales, P; Janz, S; Kupperman, E; Lee, EC; Li, P; Li, Z; Liu, R; Manfredi, M; Neppalli, VT; Pickard, M; Silva, MD; Subakan, O; Tayber, O; Terkelsen, J; Van Ness, B1
Appel, A1
Abe, M; Fujii, S1
Hu, Y; Wu, P; Zhang, J1
Cavallo, F; Genadieva-Stavric, S; Palumbo, A1
Itoh, K; Liu, T; Maruyama, A; Mimura, J; Ohyama, C; Okada, T; Sato, H; Ye, P1
Yagi, H1
D'Arrigo, P; Molla, G; Motta, P; Nardini, M; Panzeri, W; Pollegioni, L1
Mitsiades, CS1
Anderson, DR; Buisson, B; Fagiolini, M; Fanger, CM; Gleyzes, M; Gordon, E; Menniti, FS; Mierau, SB; Paschetto, K; Sirivolu, VR; Steidl, E; Virginio, C; Volkmann, RA1
Arihara, K; Ohata, M; Zhou, L1
Dorsett, KN; Hansen, KB; Menniti, FS; Mou, TC; Sprang, SR; Volkmann, RA; Yi, F1
Heffley, W; Hughes, MA; Hull, C; Joshua, M; McKinney, A; Song, EY; Taylor, BN; Xu, Z1
Tiong, IS; Wei, AH1
Eskazan, AE; Kucukyurt, S1
Cao, Y; Tong, J; Xu, Y; Zhang, L1
DiNardo, CD; Wei, AH1
Arihara, K; Ohata, M; Yada, Y; Yokoyama, I; Zhou, L1
Dutta, R; Jeng, MY; Mannis, GN; Tan, IT; Zhang, TY1
Berg, G; Cernava, T; Erschen, S; Grube, M; Kusstatscher, P; Reisenhofer-Graber, T; Wicaksono, WA1
Thol, F1
Cui, H; Hayat, K; Ho, CT; Ma, M; Wang, Z; Zhang, X1
Hayat, K; Ho, CT; Liu, M; Xu, H; Yu, J; Zhang, X; Zhou, T1

Reviews

6 review(s) available for pyrazines and glycine

ArticleYear
[Dipeptidylpeptidase IV inhibitors and dual action PPAR-agonists].
    Medizinische Monatsschrift fur Pharmazeuten, 2006, Volume: 29, Issue:3

    Topics: Adamantane; Adenosine Deaminase Inhibitors; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Glycine; Glycoproteins; Humans; Hypoglycemic Agents; Nitriles; Oxazoles; Peroxisome Proliferator-Activated Receptors; Protease Inhibitors; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Vildagliptin

2006
Clinical and marketed proteasome inhibitors for cancer treatment.
    Current medicinal chemistry, 2013, Volume: 20, Issue:20

    Topics: Boron Compounds; Boronic Acids; Bortezomib; Glycine; Humans; Lactones; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Pyrroles; Structure-Activity Relationship; Threonine

2013
New approaches to management of multiple myeloma.
    Current treatment options in oncology, 2014, Volume: 15, Issue:2

    Topics: Adult; Age Factors; Aged; Antibodies, Monoclonal; Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Depsipeptides; Frail Elderly; Glycine; Humans; Lenalidomide; Middle Aged; Multiple Myeloma; Oligopeptides; Phosphorylcholine; Proteasome Inhibitors; Pyrazines; Quality of Life; Recurrence; Thalidomide; Treatment Outcome

2014
[Proteasome inhibitor].
    Nihon rinsho. Japanese journal of clinical medicine, 2014, Volume: 72, Issue:6

    Topics: Boron Compounds; Boronic Acids; Bortezomib; Glycine; Humans; Molecular Targeted Therapy; Neoplasms; Proteasome Inhibitors; Pyrazines; Ubiquitin

2014
New drugs creating new challenges in acute myeloid leukemia.
    Genes, chromosomes & cancer, 2019, Volume: 58, Issue:12

    Topics: Aminopyridines; Aniline Compounds; Cytarabine; Daunorubicin; fms-Like Tyrosine Kinase 3; Gemtuzumab; Glycine; Humans; Leukemia, Myeloid, Acute; Pyrazines; Pyridines; Staurosporine; Triazines; United States; United States Food and Drug Administration

2019
New drugs approved for acute myeloid leukaemia in 2018.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:12

    Topics: Aniline Compounds; Antineoplastic Agents; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Clinical Trials as Topic; Disease-Free Survival; Glycine; Humans; Leukemia, Myeloid, Acute; Phenylurea Compounds; Progression-Free Survival; Pyrazines; Pyridines; Remission Induction; Sulfonamides

2019

Trials

1 trial(s) available for pyrazines and glycine

ArticleYear
Improved outcomes of octogenarians and nonagenarians with acute myeloid leukemia in the era of novel therapies.
    American journal of hematology, 2020, Volume: 95, Issue:11

    Topics: Aged, 80 and over; Aniline Compounds; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bridged Bicyclo Compounds, Heterocyclic; Cyclopentanes; Disease-Free Survival; Female; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Pyrazines; Pyridines; Pyrimidines; Retrospective Studies; Sulfonamides; Survival Rate

2020

Other Studies

42 other study(ies) available for pyrazines and glycine

ArticleYear
Effects of monoamine oxidase inhibitors on isoproterenol-induced cardiomegaly in rats.
    Toxicology and applied pharmacology, 1970, Volume: 16, Issue:1

    Topics: Animals; Carbon Isotopes; Cardiomegaly; DNA; Female; Glycine; Isocarboxazid; Isoniazid; Isoproterenol; Monoamine Oxidase Inhibitors; Myocardium; Nialamide; Nucleic Acids; Pargyline; Phenelzine; Piperidines; Pyrazines; Rats; RNA; Tranylcypromine

1970
[Biosynthesis of the basement membrane. Utilization of proline and glucose for the formation of components of the glomerular basement membrane in vitro].
    Naunyn-Schmiedebergs Archiv fur Pharmakologie, 1971, Volume: 268, Issue:1

    Topics: Animals; Basement Membrane; Carbon Isotopes; Cattle; Chromatography, Gel; Chromatography, Thin Layer; Cycloheximide; Depression, Chemical; Diuretics; Glucose; Glycine; Glycoproteins; Hydroxyproline; In Vitro Techniques; Kidney Glomerulus; Leucine; Microbial Collagenase; Peptide Hydrolases; Phlorhizin; Proline; Puromycin; Pyrazines; Rats

1971
Pyrazines as interfering substances in the determination of nitrosamines in roasted foods.
    Acta chemica Scandinavica, 1970, Volume: 24, Issue:8

    Topics: Chromatography, Gas; Food Analysis; Food Handling; Glucose; Glycine; Hot Temperature; Nitrosamines; Polarography; Pyrazines; Spectrum Analysis

1970
2-Hydroxy-3-aryl-6-methylpyrazines-fluorophores formed from the reaction of formaldehyde with cyclic enamine degradation products common to beta-lactam antibiotics with aryl glycine side chains.
    The Journal of pharmacy and pharmacology, 1981, Volume: 33, Issue:2

    Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactams; Cephalexin; Chemical Phenomena; Chemistry; Formaldehyde; Glycine; Hydrolysis; Pyrazines; Spectrometry, Fluorescence

1981
2,3-Dihydro-6,7-dichloro-pyrido[2,3-b]pyrazine-8-oxide as selective glycine antagonist with in vivo activity.
    Bioorganic & medicinal chemistry, 1997, Volume: 5, Issue:12

    Topics: Animals; Avoidance Learning; Binding Sites; Cyclic N-Oxides; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Mice; Motor Activity; N-Methylaspartate; Neuroprotective Agents; Pyrazines; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Stereotyped Behavior; Strychnine

1997
Participation of the pyrazine cation radical in the formation of mutagens in the reaction of glucose/glycine/creatinine.
    Mutation research, 1999, Jul-21, Volume: 444, Issue:1

    Topics: Cations; Creatinine; Electron Spin Resonance Spectroscopy; Food Analysis; Free Radicals; Glucose; Glycine; Hot Temperature; Maillard Reaction; Mutagenicity Tests; Mutagens; Pyrazines; Salmonella typhimurium

1999
Spiro-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives are mixed AMPA and NMDA glycine-site antagonists active in vivo.
    Bioorganic & medicinal chemistry letters, 1999, Oct-18, Volume: 9, Issue:20

    Topics: Animals; Binding Sites; Excitatory Amino Acid Antagonists; Glycine; Mice; Pyrazines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Spiro Compounds; Structure-Activity Relationship

1999
Effect of food reductones on the generation of the pyrazine cation radical and on the formation of the mutagens in the reaction of glucose, glycine and creatinine.
    Mutation research, 2000, Feb-16, Volume: 465, Issue:1-2

    Topics: Animals; Antioxidants; Ascorbic Acid; Cations; Creatinine; Electron Spin Resonance Spectroscopy; Food Analysis; Food Contamination; Free Radicals; Glucose; Glycine; In Vitro Techniques; Maillard Reaction; Microsomes, Liver; Mutagenicity Tests; Mutagens; Pyrazines; Rats; Salmonella typhimurium

2000
Interleukin-8 and leukotriene-B(4), but not formylmethionyl leucylphenylalanine, stimulate CD18-independent migration of neutrophils across human pulmonary endothelial cells in vitro.
    American journal of respiratory cell and molecular biology, 2000, Volume: 23, Issue:2

    Topics: CD11 Antigens; CD18 Antigens; Cell Line; Cell Movement; Chemotactic Factors; Dose-Response Relationship, Drug; Endothelium, Vascular; Glycine; Humans; Hydroxamic Acids; Interleukin-8; L-Selectin; Leukotriene B4; Lung; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Permeability; Phenylalanine; Protease Inhibitors; Pyrazines; Sulfonamides; Thiophenes

2000
Effects of RPR 118723, a novel antagonist at the glycine site of the NMDA receptor, in vitro.
    European journal of pharmacology, 2000, Aug-04, Volume: 401, Issue:2

    Topics: Animals; Binding, Competitive; Cerebral Cortex; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; In Vitro Techniques; Male; Membranes; Mice; N-Methylaspartate; Phencyclidine; Pyrazines; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Tritium

2000
Diastereoselective reactions in glycine templates containing an ent-ardeemin fragment.
    The Journal of organic chemistry, 2002, Apr-05, Volume: 67, Issue:7

    Topics: Alkylation; Chemistry, Organic; Crystallography, X-Ray; Glycine; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Pyrazines; Pyrimidinones; Quinazolines; Stereoisomerism

2002
Thermal degradation studies of glucose/glycine melanoidins.
    Journal of agricultural and food chemistry, 2002, Jul-03, Volume: 50, Issue:14

    Topics: Furans; Gas Chromatography-Mass Spectrometry; Glucose; Glycine; Hot Temperature; Molecular Weight; Polymers; Pyrazines; Pyrroles; Volatilization

2002
Incorporation of unprotected heterocyclic side chains into peptoid oligomers via solid-phase submonomer synthesis.
    Journal of the American Chemical Society, 2003, Jul-23, Volume: 125, Issue:29

    Topics: Acylation; Biomimetic Materials; Glycine; Imidazoles; Indoles; Peptides; Pyrazines; Pyridines; Quinolines

2003
Synthesis of cyclic endiamino peptides.
    Journal of the American Chemical Society, 2005, Jun-01, Volume: 127, Issue:21

    Topics: Alanine; Amino Acids, Diamino; Glycine; Peptides, Cyclic; Pyrazines

2005
Mechanism of formation of redox-active hydroxylated benzenes and pyrazine in 13C-labeled glycine/D-glucose model systems.
    Journal of agricultural and food chemistry, 2005, Dec-14, Volume: 53, Issue:25

    Topics: Benzene; Carbon Isotopes; Gas Chromatography-Mass Spectrometry; Glucose; Glycine; Hydroxylation; Maillard Reaction; Pyrazines

2005
Establishment of a mouse skin model of the lichenification in human chronic eczematous dermatitis.
    The British journal of dermatology, 2007, Volume: 156, Issue:5

    Topics: Animals; Disease Models, Animal; Eczema; Epidermis; Glycine; Glycine Agents; Humans; Hydroxamic Acids; Male; Metalloendopeptidases; Mice; Mice, Hairless; Pyrazines; Skin Aging; Sulfonamides

2007
Structure-reactivity relationships of flavan-3-ols on product generation in aqueous glucose/glycine model systems.
    Journal of agricultural and food chemistry, 2007, May-02, Volume: 55, Issue:9

    Topics: Catechin; Flavonoids; Glucose; Glycine; Maillard Reaction; Phenols; Pyrazines; Structure-Activity Relationship

2007
Mechanisms of alkylpyrazine formation in a potato model system containing added glycine.
    Journal of agricultural and food chemistry, 2007, May-16, Volume: 55, Issue:10

    Topics: Acrylamides; Alkylation; Amino Acids; Glycine; Hot Temperature; Isotopes; Pyrazines; Solanum tuberosum

2007
Investigations on the effect of amino acids on acrylamide, pyrazines, and Michael addition products in model systems.
    Journal of agricultural and food chemistry, 2009, Oct-14, Volume: 57, Issue:19

    Topics: Acrylamide; Amino Acids; Asparagine; Glucose; Glycine; Hot Temperature; Maillard Reaction; Models, Chemical; Pyrazines

2009
Evaluation of the proteasome inhibitor MLN9708 in preclinical models of human cancer.
    Cancer research, 2010, Mar-01, Volume: 70, Issue:5

    Topics: Animals; Boron Compounds; Boronic Acids; Bortezomib; Cysteine Proteinase Inhibitors; Drug Screening Assays, Antitumor; Female; Glycine; HCT116 Cells; HT29 Cells; Humans; Lymphoma; Mice; Mice, SCID; Neoplasms; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Xenograft Model Antitumor Assays

2010
The biosynthesis of branched dialkylpyrazines in myxobacteria.
    Chemistry & biodiversity, 2010, Volume: 7, Issue:9

    Topics: Aldehydes; Bacteriological Techniques; Carbohydrate Sequence; Culture Media; Gas Chromatography-Mass Spectrometry; Glycine; Isomerism; Myxococcales; Pyrazines; Valine; Volatilization

2010
Dimerization of azomethine ylides: an alternate route to pyrazine formation in the Maillard reaction.
    Journal of agricultural and food chemistry, 2010, Dec-08, Volume: 58, Issue:23

    Topics: Azo Compounds; Dimerization; Glycine; Maillard Reaction; Models, Chemical; Oxidation-Reduction; Pyrazines; Thiosemicarbazones

2010
Pharmacological and functional properties of TRPM8 channels in prostate tumor cells.
    Pflugers Archiv : European journal of physiology, 2011, Volume: 461, Issue:1

    Topics: Arginine; Calcium; Cell Line; Cell Line, Tumor; Cell Membrane; Clotrimazole; Cold Temperature; Endoplasmic Reticulum; Glycine; Humans; Male; Menthol; Prostate; Prostatic Neoplasms; Pyrazines; Pyridines; Pyrimidinones; TRPM Cation Channels

2011
In vitro and in vivo selective antitumor activity of a novel orally bioavailable proteasome inhibitor MLN9708 against multiple myeloma cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Aug-15, Volume: 17, Issue:16

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Biological Availability; Blotting, Western; Boron Compounds; Boronic Acids; Bortezomib; Caspase 3; Caspase 8; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dexamethasone; Drug Synergism; Enzyme Activation; Glycine; Humans; Lenalidomide; Mice; Mice, SCID; Multiple Myeloma; NF-kappa B; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Thalidomide; Xenograft Model Antitumor Assays

2011
Antitumor activity of the investigational proteasome inhibitor MLN9708 in mouse models of B-cell and plasma cell malignancies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Dec-01, Volume: 17, Issue:23

    Topics: Animals; Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Cell Line, Tumor; Glycine; Humans; Lymphoma, B-Cell; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Mice, Transgenic; Neoplasms, Plasma Cell; Osteolysis; Protease Inhibitors; Proteasome Inhibitors; Pyrazines; Xenograft Model Antitumor Assays

2011
Drugs: More shots on target.
    Nature, 2011, Dec-14, Volume: 480, Issue:7377

    Topics: Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Clinical Trials as Topic; Drug Resistance, Neoplasm; Glycine; Humans; Immunologic Factors; Lenalidomide; Multiple Myeloma; Oligopeptides; Protease Inhibitors; Pyrazines; Survival Rate; Thalidomide; Threonine

2011
Double Schiff base adducts of 2,3-butanedione with glycine: formation of pyrazine rings with the participation of amino acid carbon atoms.
    Journal of agricultural and food chemistry, 2012, Nov-14, Volume: 60, Issue:45

    Topics: Amino Acids; Diacetyl; Glycine; Maillard Reaction; Molecular Structure; Pyrazines; Schiff Bases

2012
[Molecular targeting agents for multiple myeloma].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70 Suppl 8

    Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Glycine; Histone Deacetylases; Humans; Immunologic Factors; Lactones; Lenalidomide; Molecular Targeted Therapy; Multiple Myeloma; Oligopeptides; Proteasome Inhibitors; Pyrazines; Pyrroles; Thalidomide

2012
Nrf2- and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition.
    Molecular and cellular biology, 2014, Sep-15, Volume: 34, Issue:18

    Topics: Activating Transcription Factor 4; Amino Acid Transport System y+; Antineoplastic Agents; Boronic Acids; Bortezomib; Cell Line, Tumor; Cysteine; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutathione; Glycine; HEK293 Cells; HeLa Cells; Humans; Leupeptins; NF-E2-Related Factor 2; Oligopeptides; Proteasome Endopeptidase Complex; Pyrazines; RNA, Small Interfering; Sulfasalazine; Urinary Bladder Neoplasms

2014
Aminoacetone oxidase from Streptococcus oligofermentans belongs to a new three-domain family of bacterial flavoproteins.
    The Biochemical journal, 2014, Dec-15, Volume: 464, Issue:3

    Topics: Acetone; Crystallography, X-Ray; Enzyme Activation; Flavoproteins; Glycine; Models, Molecular; Multigene Family; Oxidoreductases Acting on CH-NH Group Donors; Polyamine Oxidase; Protein Structure, Tertiary; Pyrazines; Streptococcus

2014
Therapeutic landscape of carfilzomib and other modulators of the ubiquitin-proteasome pathway.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015, Mar-01, Volume: 33, Issue:7

    Topics: Antineoplastic Agents; Boron Compounds; Boronic Acids; Bortezomib; Cell Line, Tumor; Clinical Trials as Topic; Glycine; Hematologic Neoplasms; Humans; Neoplasms; Oligopeptides; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Pyrazines; Signal Transduction; Ubiquitin

2015
MPX-004 and MPX-007: New Pharmacological Tools to Study the Physiology of NMDA Receptors Containing the GluN2A Subunit.
    PloS one, 2016, Volume: 11, Issue:2

    Topics: Animals; CA1 Region, Hippocampal; Calcium; Cells, Cultured; Dogs; Excitatory Postsynaptic Potentials; Female; Glutamic Acid; Glycine; Humans; Ion Channel Gating; Madin Darby Canine Kidney Cells; Male; Neurons; Oocytes; Protein Subunits; Pyrazines; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Sulfonamides; Xenopus

2016
Effects of odor generated from the glycine/glucose Maillard reaction on human mood and brainwaves.
    Food & function, 2016, Jun-15, Volume: 7, Issue:6

    Topics: Adult; Affect; Brain Waves; Evaluation Studies as Topic; Female; Furans; Glucose; Glycine; Humans; Hydrogen-Ion Concentration; Maillard Reaction; Male; Models, Biological; Odorants; Olfactory Perception; Pilot Projects; Pyrazines; Taste; Temperature; Volatile Organic Compounds; Young Adult

2016
Structural Basis for Negative Allosteric Modulation of GluN2A-Containing NMDA Receptors.
    Neuron, 2016, Sep-21, Volume: 91, Issue:6

    Topics: Allosteric Regulation; Allosteric Site; Animals; Crystallography; Glycine; Models, Molecular; Pyrazines; Receptors, N-Methyl-D-Aspartate; Sulfonamides; Xenopus laevis

2016
Coordinated cerebellar climbing fiber activity signals learned sensorimotor predictions.
    Nature neuroscience, 2018, Volume: 21, Issue:10

    Topics: Action Potentials; Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cerebellum; Excitatory Amino Acid Agents; Glycine; Guanine Nucleotide Exchange Factors; Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Nerve Fibers; Neural Pathways; Neurons; Neuropeptides; Principal Component Analysis; Pyrazines; Reaction Time; Synaptic Transmission

2018
An Alkylpyrazine Synthesis Mechanism Involving l-Threonine-3-Dehydrogenase Describes the Production of 2,5-Dimethylpyrazine and 2,3,5-Trimethylpyrazine by Bacillus subtilis.
    Applied and environmental microbiology, 2019, 12-15, Volume: 85, Issue:24

    Topics: Acetone; Acetyl Coenzyme A; Acetyltransferases; Alcohol Oxidoreductases; Bacillus subtilis; Catalysis; Flavoring Agents; Glycine; Pyrazines; Threonine

2019
How I treat acute myeloid leukemia in the era of new drugs.
    Blood, 2020, 01-09, Volume: 135, Issue:2

    Topics: Adult; Aged; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Biomarkers, Tumor; Bridged Bicyclo Compounds, Heterocyclic; Cytarabine; Daunorubicin; Female; fms-Like Tyrosine Kinase 3; Glycine; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Molecular Targeted Therapy; Mutation; Prognosis; Pyrazines; Pyridines; Sialic Acid Binding Ig-like Lectin 3; Staurosporine; Sulfonamides; Triazines

2020
2,3-Dimethylpyrazine (3DP) and 2,5-dimethyl-4-hydroxy-3(2
    Bioscience, biotechnology, and biochemistry, 2020, Volume: 84, Issue:9

    Topics: Anger; Anxiety; Autonomic Nervous System; Central Nervous System; Female; Food; Furans; Glucose; Glycine; Humans; Maillard Reaction; Male; Odorants; Pyrazines; Young Adult

2020
Antimicrobial-specific response from resistance gene carriers studied in a natural, highly diverse microbiome.
    Microbiome, 2021, 01-27, Volume: 9, Issue:1

    Topics: Anti-Infective Agents; Ascomycota; Colistin; Drug Resistance, Microbial; Glycine; Glyphosate; Microbiota; Pyrazines; RNA, Ribosomal, 16S; Tetracycline

2021
What to use to treat AML: the role of emerging therapies.
    Hematology. American Society of Hematology. Education Program, 2021, 12-10, Volume: 2021, Issue:1

    Topics: Aged; Aminopyridines; Aniline Compounds; Antineoplastic Agents; Cytarabine; Daunorubicin; Drug Approval; Drug Discovery; Glycine; Humans; Leukemia, Myeloid, Acute; Male; Neoplasm Recurrence, Local; Pyrazines; Pyridines; Triazines

2021
Controlled Formation of Pyrazines: Inhibition by Ellagic Acid Interaction with
    Journal of agricultural and food chemistry, 2022, Feb-09, Volume: 70, Issue:5

    Topics: Ellagic Acid; Glycine; Maillard Reaction; Oxidation-Reduction; Pyrazines

2022
Formation Priority of Pyrazines and 2-Acetylthiazole Dependent on the Added Cysteine and Fragments of Deoxyosones during the Thermal Process of the Glycine-Ribose Amadori Compound.
    Journal of agricultural and food chemistry, 2022, Sep-21, Volume: 70, Issue:37

    Topics: Cysteamine; Cysteine; Glycine; Glyoxal; Magnesium Oxide; Maillard Reaction; Pyrazines; Pyruvaldehyde; Ribose; Thiazoles

2022