pyrazines has been researched along with glycerol in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.09) | 18.7374 |
| 1990's | 21 (63.64) | 18.2507 |
| 2000's | 5 (15.15) | 29.6817 |
| 2010's | 4 (12.12) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alberti, KG; Catalano, C; Farrer, M; Fulcher, GR; Walker, M | 1 |
| Agius, L; Alberti, KG; Catalano, C; Fulcher, GR; Walker, M | 1 |
| Guglielmone, C; Lanzi, R; Monzani, M; Musatti, L; Pontiroli, AE; Pozza, G | 1 |
| Alberti, KG; Farrer, M; Fulcher, GR; Johnson, AJ; Record, CO | 1 |
| Duanmu, C; Hamel, E; Lin, CM | 1 |
| Betteridge, DJ; Campbell, RR; Foster, K; McAleer, M; Mundy, D; Reckless, JP; Stirling, C | 1 |
| Mandel, LR | 1 |
| Andreotti, AC; Caumo, A; Lanzi, R; Manzoni, MF; Moreschi, A; Pontiroli, AE | 1 |
| Cathelineau, G; Gautier, JF; Jandrain, B; Lacroix, M; Lefèbvre, PJ; Mosora, F; Pirnay, F; Scheen, AJ | 1 |
| Bolli, GB; Brunetti, P; Ciofetta, M; Di Vincenzo, A; Epifano, L; Fanelli, C; Lepore, M; Modarelli, F; Pampanelli, S | 1 |
| Ekstrand, A; Eriksson, J; Franssila-Kallunki, A; Groop, L; Saloranta, C; Taskinen, MR | 1 |
| Groop, L; Härkönen, M; Melander, A; Saloranta, C; Taskinen, MR; Widen, E | 1 |
| Braatvedt, G; Corrall, RJ; Newrick, PG; Stansbie, D | 1 |
| Alberti, KG; Berrish, TS; Cooper, BG; Elliott, C; Orskov, H; Reed, JW; Walker, M | 1 |
| Alberti, KG; Farrer, M; Fulcher, GR; Johnson, AS; Walker, M | 1 |
| Akanji, AO; Hockaday, TD; Kirk, M; Osifo, E | 1 |
| Alberti, KG; Christie, AW; Emmison, N; Kraemer, FB; McCormick, DK; Yeaman, SJ | 1 |
| Alberti, KG; Brown, MD; Conti, M; Davis, SN; Monti, LD; Piatti, PM; Pozza, G | 1 |
| Anh-Le, N; Bodkin, NL; Hannah, JS; Hansen, BC; Howard, BV; Paidi, MS | 1 |
| A-Rahim, YI; Beyer, KH; Vesell, ES | 1 |
| Emery, PW; Obeid, OA | 1 |
| Andreotti, AC; Bianchi, E; Caumo, A; Lanzi, R; Luzi, L; Malighetti, ME; Manzoni, MF; Pontiroli, AE; Sereni, LP | 1 |
| Bolli, GB | 1 |
| Brouwer, EM; Saris, WH; Schiffelers, SL; van Baak, MA | 1 |
| Guo, W; Han, J; Wang-Fisher, YL | 1 |
| Christiansen, JS; Jørgensen, JO; Møller, N; Nielsen, S; Nørrelund, H | 1 |
| Andrews, GP; Donnelly, RF; McCarron, PA; Woolfson, AD | 1 |
| Carey, PE; Cline, GW; Cobelli, C; Dalla Man, C; English, PT; Firbank, MJ; Gerrard, J; Taylor, R | 1 |
| Cameron-Smith, D; Hargreaves, M; McAinch, AJ; Tunstall, RJ; van Loon, LJ | 1 |
| Hainer, V; Hill, M; Nedvidkova, J; Papezova, H; Smitka, K; Vondra, K | 1 |
| Kim, JO; Li, G; Marasini, N; Quan, Q; Wei, L; Yong, CS | 1 |
| Ding, X; Huang, J; Sun, J; Wang, P | 1 |
| Elliott, JAW; Hahn, J; Jomha, NM; Korbutt, GS; Laouar, L | 1 |
14 trial(s) available for pyrazines and glycerol
| Article | Year |
|---|---|
Acute metabolic and hormonal responses to the inhibition of lipolysis in non-obese patients with non-insulin-dependent (type 2) diabetes mellitus: effects of acipimox.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Diabetes Mellitus, Type 2; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glycerol; Humans; Hydrocortisone; Hydroxybutyrates; Hypolipidemic Agents; Lipolysis; Male; Middle Aged; Norepinephrine; Pyrazines | 1992 |
Metabolic effects of suppression of nonesterified fatty acid levels with acipimox in obese NIDDM subjects.
Topics: 3-Hydroxybutyric Acid; Alanine; Blood Glucose; Cholesterol; Diabetes Mellitus; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glycerol; Humans; Hydroxybutyrates; Hypolipidemic Agents; Insulin; Lactates; Male; Middle Aged; Obesity; Pyrazines; Pyruvates; Triglycerides | 1992 |
Plasma free fatty acids and serum insulin in subjects feeding at 12-hour intervals; effects of methionyl growth hormone and of acipimox, an inhibitor of lipolysis.
Topics: Circadian Rhythm; Double-Blind Method; Fatty Acids, Nonesterified; Food; Glycerol; Growth Hormone; Hormones; Human Growth Hormone; Humans; Insulin; Lipolysis; Male; Pyrazines | 1992 |
Effect of acute inhibition of lipolysis on operation of the glucose-fatty acid cycle in hepatic cirrhosis.
Topics: 3-Hydroxybutyric Acid; Aged; Blood Glucose; Fatty Acids; Fatty Acids, Nonesterified; Glucose Tolerance Test; Glycerol; Humans; Hydroxybutyrates; Hypolipidemic Agents; Insulin Resistance; Lipolysis; Liver Cirrhosis; Male; Middle Aged; Pyrazines; Reference Values | 1992 |
Acute pharmacologic blockade of lipolysis normalizes nocturnal growth hormone levels and pulsatility in obese subjects.
Topics: Administration, Oral; Adult; Blood Glucose; Body Mass Index; Circadian Rhythm; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Fatty Acids, Nonesterified; Female; Glycerol; Growth Hormone; Humans; Hypolipidemic Agents; Insulin; Insulin-Like Growth Factor I; Lipolysis; Male; Middle Aged; Obesity; Pulsatile Flow; Pyrazines | 1994 |
Availability of glucose ingested during muscle exercise performed under acipimox-induced lipolysis blockade.
Topics: Administration, Oral; Adult; Blood Glucose; C-Peptide; Calorimetry, Indirect; Carbohydrate Metabolism; Energy Metabolism; Glucagon; Glucose; Glycerol; Humans; Hypolipidemic Agents; Insulin; Lipid Metabolism; Lipolysis; Male; Oxidation-Reduction; Physical Exertion; Pyrazines | 1994 |
Metabolic consequences of sustained suppression of free fatty acids by acipimox in patients with NIDDM.
Topics: Blood Glucose; Calorimetry; Chromatography, High Pressure Liquid; Circadian Rhythm; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Fatty Acids, Nonesterified; Female; Glucagon; Glucose; Glycerol; Growth Hormone; Humans; Hydrocortisone; Hypolipidemic Agents; Insulin; Liver; Male; Middle Aged; Pyrazines; Time Factors | 1993 |
Suppression of lipolysis in normal man does not inhibit recovery from insulin-induced hypoglycaemia.
Topics: Acetoacetates; Adult; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Fatty Acids, Nonesterified; Female; Glycerol; Humans; Hyperlipidemias; Hypoglycemia; Hypolipidemic Agents; Insulin; Lipolysis; Male; Pyrazines | 1993 |
The role of plasma non-esterified fatty acids during exercise in type 2 diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; C-Peptide; Calorimetry; Carbon Dioxide; Diabetes Mellitus, Type 2; Energy Metabolism; Exercise; Fatty Acids, Nonesterified; Female; Glucagon; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Hypolipidemic Agents; Insulin; Lactates; Male; Middle Aged; Nitrogen; Oxygen Consumption; Pyrazines; Reference Values | 1993 |
Acipimox increases glucose disposal in normal man independent of changes in plasma nonesterified fatty acid concentration and whole-body lipid oxidation rate.
Topics: Adult; Alanine; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Growth Hormone; Humans; Hydroxybutyrates; Hypolipidemic Agents; Insulin; Lactates; Lipid Metabolism; Male; Oxidation-Reduction; Pyrazines; Pyruvates; Radioimmunoassay; Time Factors | 1993 |
The effects of changes in plasma nonesterified fatty acid levels on oxidative metabolism during moderate exercise in patients with non-insulin-dependent diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Blood Glucose; Calorimetry, Indirect; Diabetes Mellitus, Type 2; Exercise; Fatty Acids, Nonesterified; Glycerol; Growth Hormone; Heparin; Humans; Hydroxybutyrates; Hypolipidemic Agents; Insulin; Ketone Bodies; Male; Middle Aged; Norepinephrine; Pyrazines; Triglycerides | 1993 |
Effects of an acute decrease in non-esterified fatty acid levels on muscle glucose utilization and forearm indirect calorimetry in lean NIDDM patients.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Forearm; Glucose; Glucose Tolerance Test; Glycerol; Glycogen; Humans; Hydroxybutyrates; Hypolipidemic Agents; Kinetics; Middle Aged; Muscle, Skeletal; Pyrazines; Regional Blood Flow; Thinness; Time Factors | 1996 |
Evidence for an inhibitory effect of physiological levels of insulin on the growth hormone (GH) response to GH-releasing hormone in healthy subjects.
Topics: Adult; Cross-Over Studies; Fatty Acids, Nonesterified; Female; Glycerol; Growth Hormone; Growth Hormone-Releasing Hormone; Humans; Hypolipidemic Agents; Insulin; Male; Pyrazines; Single-Blind Method; Time Factors | 1997 |
Reduced plasma free fatty acid availability during exercise: effect on gene expression.
Topics: Administration, Oral; Animals; Carnitine O-Palmitoyltransferase; Cell Line; Cross-Over Studies; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Gene Expression; Glycerol; Heat-Shock Proteins; Humans; Hypolipidemic Agents; Ion Channels; Lipid Metabolism; Male; Mitochondrial Proteins; Muscle Fibers, Skeletal; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Physical Endurance; Protein Kinases; Pyrazines; Rats; RNA-Binding Proteins; RNA, Messenger; Time Factors; Transcription Factors; Uncoupling Protein 3 | 2007 |
19 other study(ies) available for pyrazines and glycerol
| Article | Year |
|---|---|
Tubulin polymerization with ATP is mediated through the exchangeable GTP site.
Topics: Adenosine Triphosphate; Animals; Cattle; Cyclic AMP; Glycerol; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Maytansine; Pyrazines; Tubulin | 1986 |
Effects of acipimox, a nicotinic acid derivative, on lipolysis in human adipose tissue and on cholesterol synthesis in human jejunal mucosa.
Topics: Adipose Tissue; Cholesterol; Fatty Acids; Glycerol; Humans; Hypolipidemic Agents; In Vitro Techniques; Intestinal Mucosa; Isoproterenol; Jejunum; Lipolysis; Pyrazines | 1985 |
Inhibition of cyclic 3',5'-adenosine monophosphate phosphodiesterase by substituted imidazopyrazines.
Topics: Adenylyl Cyclases; Adipose Tissue; Animals; Bronchodilator Agents; Carbon Isotopes; Cattle; Cyclic AMP; Female; Glycerol; Heart; Imidazoles; In Vitro Techniques; Lung; Myocardium; Norepinephrine; Pancreas; Phosphoric Monoester Hydrolases; Pyrazines; Rabbits; Rats; Structure-Activity Relationship; Theophylline; Uterus; Vasodilator Agents | 1971 |
Post-hypoglycaemic hyperketonaemia does not contribute to brain metabolism during insulin-induced hypoglycaemia in humans.
Topics: 3-Hydroxybutyric Acid; Adult; Alanine; Brain; Cognition; Diabetes Mellitus, Type 1; Female; Glycerol; Homeostasis; Hormones; Humans; Hydroxybutyrates; Hypoglycemia; Hypolipidemic Agents; Insulin; Insulinoma; Ketone Bodies; Lactates; Lipolysis; Male; Pancreatic Neoplasms; Pyrazines; Reaction Time | 1993 |
Different acute and chronic effects of acipimox treatment on glucose and lipid metabolism in patients with type 2 diabetes.
Topics: Blood Glucose; Cholesterol; Cholesterol, HDL; Circadian Rhythm; Diabetes Mellitus, Type 2; Fasting; Fatty Acids, Nonesterified; Female; Glucose; Glucose Clamp Technique; Glycerol; Humans; Hypolipidemic Agents; Infusions, Intravenous; Insulin; Lipids; Liver; Male; Middle Aged; Pyrazines; Time Factors; Triglycerides | 1993 |
Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes.
Topics: Adenosine Deaminase; Adipocytes; Animals; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Glycerol; Hypolipidemic Agents; Isoproterenol; Kinetics; Lipase; Lipolysis; Male; Pyrazines; Rats; Rats, Wistar; Subcellular Fractions | 1996 |
Effects of Acipimox on the metabolism of free fatty acids and very low lipoprotein triglyceride.
Topics: Animals; Blood Glucose; Cholesterol, LDL; Cholesterol, VLDL; Eating; Fatty Acids, Nonesterified; Glucose Clamp Technique; Glycerol; Humans; Hypolipidemic Agents; Infusions, Intravenous; Insulin; Lipoproteins, VLDL; Macaca mulatta; Male; Pyrazines; Reference Values; Triglycerides; Tritium | 1995 |
Studies on pyrazinoylguanidine. 3. Downregulation of lipolysis in isolated adipocytes.
Topics: Adipocytes; Adrenergic beta-Agonists; Animals; Colforsin; Cyclic AMP; Down-Regulation; Glycerol; Guanidines; Hypoglycemic Agents; In Vitro Techniques; Isoproterenol; Lipase; Lipolysis; Male; Pertussis Toxin; Pyrazines; Rats; Rats, Sprague-Dawley; Virulence Factors, Bordetella | 1996 |
Effect of acute acipimox administration on the rates of lipid and glycogen synthesis in cachectic tumor-bearing rats.
Topics: Animals; Blood Glucose; Cachexia; Gluconeogenesis; Glucose; Glycerol; Glycogen; Hypolipidemic Agents; Leydig Cell Tumor; Lipids; Lipolysis; Male; Pyrazines; Rats; Rats, Inbred F344; Testicular Neoplasms | 1997 |
Importance of catecholamines in defense against insulin hypoglycemia in humans.
Topics: Blood Glucose; Epinephrine; Fatty Acids, Nonesterified; Glucagon; Glucose; Glycerol; Heparin; Homeostasis; Human Growth Hormone; Humans; Hydrocortisone; Hypoglycemia; Hypolipidemic Agents; Insulin; Lipolysis; Phentolamine; Propranolol; Pyrazines | 1998 |
Inhibition of lipolysis reduces beta1-adrenoceptor-mediated thermogenesis in man.
Topics: Adrenergic beta-Agonists; Adult; Blood Chemical Analysis; Blood Pressure; Body Temperature Regulation; Carbohydrate Metabolism; Dobutamine; Energy Metabolism; Fatty Acids, Nonesterified; Glycerol; Heart Rate; Humans; Hypolipidemic Agents; Lipid Metabolism; Lipolysis; Male; Pyrazines; Receptors, Adrenergic, beta-1; Respiration | 1998 |
Acipimox stimulates leptin production from isolated rat adipocytes.
Topics: Adipocytes; Animals; Bucladesine; Cells, Cultured; Female; Glycerol; Hypolipidemic Agents; Insulin; Leptin; Lipolysis; Niacin; Norepinephrine; Pyrazines; Rats; Rats, Sprague-Dawley; Stimulation, Chemical | 2002 |
Modulation of basal glucose metabolism and insulin sensitivity by growth hormone and free fatty acids during short-term fasting.
Topics: Adult; Amino Acids; Blood Flow Velocity; Blood Glucose; Calorimetry, Indirect; Fasting; Fatty Acids, Nonesterified; Forearm; Glucagon; Glucose Clamp Technique; Glycerol; Human Growth Hormone; Humans; Insulin; Insulin Resistance; Lactic Acid; Lipolysis; Male; Microdialysis; Plethysmography; Pyrazines; Somatostatin | 2004 |
Stability of 5-aminolevulinic acid in novel non-aqueous gel and patch-type systems intended for topical application.
Topics: Aminolevulinic Acid; Chemistry, Pharmaceutical; Dimerization; Drug Stability; Drug Storage; Gels; Glycerol; Photosensitizing Agents; Polyethylene Glycols; Pyrazines; Temperature; Time Factors; Tissue Adhesives | 2005 |
Acute inhibition of lipolysis does not affect postprandial suppression of endogenous glucose production.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Female; Food; Glucagon; Glucose; Glycerol; Humans; Hypolipidemic Agents; Insulin; Kinetics; Lipolysis; Liver; Magnetic Resonance Spectroscopy; Male; Middle Aged; Oxidation-Reduction; Placebos; Pyrazines; Triglycerides | 2005 |
Acipimox during exercise points to an inhibitory feedback of GH on ghrelin secretion in bulimic and healthy women.
Topics: Adult; Body Mass Index; Bulimia Nervosa; Case-Control Studies; Exercise; Fatty Acids, Nonesterified; Feedback, Physiological; Female; Gastric Mucosa; Ghrelin; Glycerol; Human Experimentation; Human Growth Hormone; Humans; Hypolipidemic Agents; Neuropeptide Y; Pituitary Gland; Pyrazines; Stomach | 2011 |
Development of ligustrazine-loaded lipid emulsion: formulation optimization, characterization and biodistribution.
Topics: Animals; Cells, Cultured; Chemistry, Pharmaceutical; Drug Delivery Systems; Drug Stability; Emulsions; Erythrocytes; Glycerol; Hemolysis; Lecithins; Male; Oleic Acid; Poloxamer; Pyrazines; Rabbits; Rats; Rats, Sprague-Dawley; Soybean Oil; Tissue Distribution | 2012 |
Efficient Enantioselective Biocatalytic Production of a Chiral Intermediate of Sitagliptin by a Newly Filamentous Fungus Isolate.
Topics: Biocatalysis; Chromatography, High Pressure Liquid; Fungi; Glycerol; Hydrogen-Ion Concentration; Phylogeny; Pyrazines; Sitagliptin Phosphate; Stereoisomerism; Temperature | 2016 |
The effect of additive compounds on glycerol-induced damage to human chondrocytes.
Topics: Aged; Aged, 80 and over; Ascorbic Acid; Cartilage, Articular; Cell Survival; Chondrocytes; Chondroitin Sulfates; Cryopreservation; Cryoprotective Agents; Glucosamine; Glycerol; Humans; Middle Aged; Pyrazines; Vitrification | 2017 |